Chi-Hao Luan

  • 1862 Citations
1984 …2021
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Personal profile

Education/Academic qualification

Computer and Information Sciences, MS, University of Alabama at Birmingham

… → 2001

Molecular Biophysics, PhD, University of Alabama at Birmingham

… → 1993

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Elastin Chemical Compounds
Transition Temperature Medicine & Life Sciences
Proteins Medicine & Life Sciences
Hydrophobic and Hydrophilic Interactions Medicine & Life Sciences
Peptides Chemical Compounds
Hydrophobicity Chemical Compounds
Hot Temperature Medicine & Life Sciences
valyl-prolyl-glycyl-valyl-glycine Chemical Compounds

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Grants 2010 2021

Ubiquitin
Recycling
Neurodegenerative Diseases
Pharmaceutical Preparations
Libraries
Cyclic Nucleotides
Antidepressive Agents
Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels
Major Depressive Disorder
Fluorescence Polarization
Cyclic Nucleotides
Antidepressive Agents
Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels
Major Depressive Disorder
Fluorescence Polarization

Research Output 1984 2019

Antibacterial activity of 2-amino-4-hydroxypyrimidine-5-carboxylates and binding to Burkholderia pseudomallei 2-C-methyl-D-erythritol-2,4-cyclodiphosphate synthase

Watkins, S. M., Ghose, D., Blain, J. M., Grote, D. L., Luan, C-H., Clare, M., Meganathan, R., Horn, J. R. & Hagen, T. J., Oct 15 2019, In : Bioorganic and Medicinal Chemistry Letters. 29, 20, 126660.

Research output: Contribution to journalArticle

Burkholderia pseudomallei
Zinc
Epitope Mapping
Mammals
Biosynthesis

Unique structural features of a bacterial autotransporter adhesin suggest mechanisms for interaction with host macromolecules

Paxman, J. J., Lo, A. W., Sullivan, M. J., Panjikar, S., Kuiper, M., Whitten, A. E., Wang, G., Luan, C-H., Moriel, D. G., Tan, L., Peters, K. M., Phan, M. D., Gee, C. L., Ulett, G. C., Schembri, M. A. & Heras, B., Dec 1 2019, In : Nature communications. 10, 1, 1967.

Research output: Contribution to journalArticle

Open Access
Bacterial Adhesins
Macromolecules
macromolecules
proteins
infectious diseases
7 Citations (Scopus)

Aspirin binds to PPARα to stimulate hippocampal plasticity and protect memory

Patel, D., Roy, A., Kundu, M., Jana, M., Luan, C. H., Gonzalez, F. J. & Pahan, K., Jul 31 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 31, p. E7408-E7417

Research output: Contribution to journalArticle

PPAR alpha
Aspirin
Ligands
Cyclic AMP Response Element-Binding Protein
Dendritic Spines
5 Citations (Scopus)

Selective disruption of TLR2/MyD88 interaction inhibits inflammation and attenuates Alzheimer's pathology

Rangasamy, S. B., Jana, M., Roy, A., Corbett, G. T., Kundu, M., Chandra, S., Mondal, S., Dasarathi, S., Mufson, E. J., Mishra, R. K., Luan, C-H., Bennett, D. A. & Pahan, K., Jul 10 2018, In : The Journal of clinical investigation.

Research output: Contribution to journalArticle

Pathology
Inflammation
Peptides
Alzheimer Disease
Hippocampus
2 Citations (Scopus)

Retraction: Structure and mechanism of the essential two-component signal-transduction system WalKR in Staphylococcus aureus (Nature Communications (2016) 7 (11000) DOI: 10.1038/ncomms11000)

Ji, Q., Chen, P. J., Qin, G., Deng, X., Hao, Z., Wawrzak, Z., Yeo, W. S., Quang, J. W., Cho, H., Luo, G. Z., Weng, X., You, Q., Luan, C-H., Yang, X., Bae, T., Yu, K., Jiang, H. & He, C., Feb 6 2017, In : Nature communications. 8, 14331.

Research output: Contribution to journalComment/debate

Signal transduction
staphylococcus
Staphylococcus aureus
Signal Transduction
communication