Grants per year
Personal profile
Research Interests
Professor Petersen's lab studies the molecular and cellular mechanisms that underlie animal regeneration. Tissue repair processes are likely ancient, and this ability is highly exaggerated in flatworm planarians, which use adult pluripotent stem cells to regenerate a complex anatomy after any injury, even decapitation. Current work uses this model system for identifying components of spatial control systems that link tissue injury to regulation of identity and extent of regenerative outgrowths.
Education/Academic qualification
Biology, PhD, Massachusetts Institute of Technology
2000 → 2006
Chemistry and History, BA, Grinnell College
1996 → 2000
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Collaborations and top research areas from the last five years
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Regulation of whole-body regeneration
Petersen, C. P. & Petersen, C. P.
National Institute of General Medical Sciences
4/1/23 → 3/31/28
Project: Research project
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Cell signaling in regeneration and tissue scaling
National Institute of General Medical Sciences
4/1/19 → 2/29/24
Project: Research project
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Enhancement of neural regeneration
National Institute of General Medical Sciences
9/1/19 → 7/30/23
Project: Research project
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Regulatory Circuits Controlling Regenerative Growth
National Institute of Dental and Craniofacial Research
9/18/13 → 6/30/18
Project: Research project
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Wnt signaling in whole-body regeneration
Petersen, C. P., Jan 2023, Wnt Signaling in Development and Disease. Yamaguchi, T. P. & Willert, K. (eds.). Academic Press Inc, p. 347-380 34 p. (Current Topics in Developmental Biology; vol. 153).Research output: Chapter in Book/Report/Conference proceeding › Chapter
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A Wnt11 and Dishevelled signaling pathway acts prior to injury to control wound polarization for the onset of planarian regeneration
Gittin, D. I. & Petersen, C. P., Dec 19 2022, In: Current Biology. 32, 24, p. 5262-5273.e2Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Src acts with WNT/FGFRL signaling to pattern the planarian anteroposterior axis
Bonar, N. A., Gittin, D. I. & Petersen, C. P., Apr 1 2022, In: Development (Cambridge, England). 149, 7Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
STRIPAK Limits Stem Cell Differentiation of a WNT Signaling Center to Control Planarian Axis Scaling
Schad, E. G. & Petersen, C. P., Jan 20 2020, In: Current Biology. 30, 2, p. 254-263.e2Research output: Contribution to journal › Article › peer-review
Open Access11 Scopus citations -
Tec-1 kinase negatively regulates regenerative neurogenesis in planarians
Karge, A., Bonar, N. A., Wood, S. & Petersen, C. P., Jan 2020, In: eLife. 9, e47293.Research output: Contribution to journal › Article › peer-review
Open Access10 Scopus citations