Grants per year
Personal profile
Research Interests
Professor Petersen's lab studies the molecular and cellular mechanisms that underlie animal regeneration. Tissue repair processes are likely ancient, and this ability is highly exaggerated in flatworm planarians, which use adult pluripotent stem cells to regenerate a complex anatomy after any injury, even decapitation. Current work uses this model system for identifying components of spatial control systems that link tissue injury to regulation of identity and extent of regenerative outgrowths.
Education/Academic qualification
Biology, PhD, Massachusetts Institute of Technology
2000 → 2006
Chemistry and History, BA, Grinnell College
1996 → 2000
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Grants
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Enhancement of neural regeneration
National Institute of General Medical Sciences
9/1/19 → 7/30/23
Project: Research project
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Cell signaling in regeneration and tissue scaling
National Institute of General Medical Sciences
4/1/19 → 2/28/23
Project: Research project
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Regulatory Circuits Controlling Regenerative Growth
National Institute of Dental and Craniofacial Research
9/18/13 → 6/30/18
Project: Research project
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Identification of Genes Involved in Pattern Control During Regeneration
1/1/11 → 12/31/11
Project: Research project
Research Output
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STRIPAK Limits Stem Cell Differentiation of a WNT Signaling Center to Control Planarian Axis Scaling
Schad, E. G. & Petersen, C. P., Jan 20 2020, In: Current Biology. 30, 2, p. 254-263.e2Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Tec-1 kinase negatively regulates regenerative neurogenesis in planarians
Karge, A., Bonar, N. A., Wood, S. & Petersen, C. P., Jan 2020, In: eLife. 9, e47293.Research output: Contribution to journal › Article › peer-review
Open Access -
A small set of conserved genes, including sp5 and Hox, are activated by Wnt signaling in the posterior of planarians and acoels
Tewari, A. G., Owen, J. H., Petersen, C. P., Wagner, D. E. & Reddien, P. W., 2019, In: PLoS genetics. 15, 10, e1008401.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Positional information specifies the site of organ regeneration and not tissue maintenance in planarians
Hill, E. M. & Petersen, C. P., Mar 16 2018, In: eLife. 7, e33680.Research output: Contribution to journal › Article › peer-review
8 Scopus citations -
Activation of planarian TRPA1 by reactive oxygen species reveals a conserved mechanism for animal nociception
Arenas, O. M., Zaharieva, E. E., Para, A., Vásquez-Doorman, C., Petersen, C. P. & Gallio, M., Dec 1 2017, In: Nature neuroscience. 20, 12, p. 1686-1693 8 p.Research output: Contribution to journal › Article › peer-review
39 Scopus citations