Christine Marie Hoeman

  • 943 Citations
20082019

Research output per year

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Research Output

  • 943 Citations
  • 19 Article
  • 3 Review article
2019

ACVR1 R206H cooperates with H3.1K27M in promoting diffuse intrinsic pontine glioma pathogenesis

Hoeman, C. M., Cordero, F. J., Hu, G., Misuraca, K., Romero, M. M., Cardona, H. J., Nazarian, J., Hashizume, R., McLendon, R., Yu, P., Procissi, D., Gadd, S. L. & Becher, O. J., Mar 4 2019, In : Nature communications. 10, 1, 1023.

Research output: Contribution to journalArticle

15 Scopus citations

A new IRF-1–driven apoptotic pathway triggered by IL-4/IL-13 kills neonatal Th1 cells and weakens protection against viral infection

Miller, M. M., Barik, S., Cattin-Roy, A. N., Ukah, T. K., Hoeman, C. M. & Zaghouani, H., Jun 1 2019, In : Journal of Immunology. 202, 11, p. 3173-3186 14 p.

Research output: Contribution to journalArticle

2018

CDK4/6 and PDGFRA signaling as therapeutic targets in diffuse intrinsic pontine glioma

Hoeman, C., Shen, C. & Becher, O. J., May 31 2018, In : Frontiers in Oncology. 8, MAY, 191.

Research output: Contribution to journalReview article

5 Scopus citations
2015

A high-throughput in Vitro drug screen in a genetically engineered mouse model of diffuse intrinsic pontine glioma identifies BMS-754807 as a promising therapeutic agent

Halvorson, K. G., Barton, K. L., Schroeder, K., Misuraca, K. L., Hoeman, C., Chung, A., Crabtree, D. M., Cordero, F. J., Singh, R., Spasojevic, I., Berlow, N., Pal, R. & Becher, O. J., Mar 6 2015, In : PloS one. 10, 3, e0118926.

Research output: Contribution to journalArticle

29 Scopus citations
2014

Children are not just little adults: Recent advances in understanding of diffuse intrinsic pontine glioma biology

Schroeder, K. M., Hoeman, C. M. & Becher, O. J., Jan 1 2014, In : Pediatric Research. 75, 1-2, p. 205-209 5 p.

Research output: Contribution to journalReview article

30 Scopus citations

Genomic analysis of diffuse intrinsic pontine gliomas identifies three molecular subgroups and recurrent activating ACVR1 mutations

Buczkowicz, P., Hoeman, C., Rakopoulos, P., Pajovic, S., Letourneau, L., Dzamba, M., Morrison, A., Lewis, P., Bouffet, E., Bartels, U., Zuccaro, J., Agnihotri, S., Ryall, S., Barszczyk, M., Chornenkyy, Y., Bourgey, M., Bourque, G., Montpetit, A., Cordero, F., Castelo-Branco, P. & 32 others, Mangerel, J., Tabori, U., Ho, K. C., Huang, A., Taylor, K. R., Mackay, A., Bendel, A. E., Nazarian, J., Fangusaro, J. R., Karajannis, M. A., Zagzag, D., Foreman, N. K., Donson, A., Hegert, J. V., Smith, A., Chan, J., Lafay-Cousin, L., Dunn, S., Hukin, J., Dunham, C., Scheinemann, K., Michaud, J., Zelcer, S., Ramsay, D., Cain, J., Brennan, C., Souweidane, M. M., Jones, C., Allis, C. D., Brudno, M., Becher, O. & Hawkins, C., May 2014, In : Nature Genetics. 46, 5, p. 451-456 6 p.

Research output: Contribution to journalArticle

284 Scopus citations

IL-13Rα1 is a surface marker for M2 macrophages influencing their differentiation and function

Dhakal, M., Hardaway, J. C., Guloglu, F. B., Miller, M. M., Hoeman, C. M., Zaghouani, A. A., Wan, X., Rowland, L. M., Cascio, J. A., Sherman, M. P. & Zaghouani, H., Jan 1 2014, In : European Journal of Immunology. 44, 3, p. 842-855 14 p.

Research output: Contribution to journalArticle

21 Scopus citations
2013

Antigen-free adjuvant assists late effector CD4 t cells to transit to memory in lymphopenic hosts

Guloglu, F. B., Ellis, J. S., Wan, X., Dhakal, M., Hoeman, C. M., Cascio, J. A. & Zaghouani, H., Aug 1 2013, In : Journal of Immunology. 191, 3, p. 1126-1135 10 p.

Research output: Contribution to journalArticle

3 Scopus citations

Developmental expression of IL-12Rβ2 on murine naive neonatal T cells counters the upregulation of IL-13Rα1 on primary Th1 cells and balances immunity in the newborn

Hoeman, C. M., Dhakal, M., Zaghouani, A. A., Cascio, J. A., Wan, X., Khairallah, M. T., Chen, W. & Zaghouani, H., Jun 15 2013, In : Journal of Immunology. 190, 12, p. 6155-6163 9 p.

Research output: Contribution to journalArticle

8 Scopus citations

Recovery from overt type 1 diabetes ensues when immune tolerance and β-Cell formation are coupled with regeneration of endothelial cells in the pancreatic islets

Wan, X., Guloglu, F. B., VanMorlan, A. M., Rowland, L. M., Zaghouani, S., Cascio, J. A., Dhakal, M., Hoeman, C. M. & Zaghouani, H., Aug 1 2013, In : Diabetes. 62, 8, p. 2879-2889 11 p.

Research output: Contribution to journalArticle

11 Scopus citations
2012

Bone marrow-derived IL-13Ra1-positive thymic progenitors are restricted to the myeloid lineage

Haymaker, C. L., Guloglu, F. B., Cascio, J. A., Hardaway, J. C., Dhakal, M., Wan, X., Hoeman, C. M., Zaghouani, S., Rowland, L. M., Tartar, D. M., VanMorlan, A. M. & Zaghouani, H., Apr 1 2012, In : Journal of Immunology. 188, 7, p. 3208-3216 9 p.

Research output: Contribution to journalArticle

11 Scopus citations

Mechanisms underlying antigen-specific tolerance of stable and convertible Th17 cells during suppression of autoimmune diabetes

Wan, X., Guloglu, F. B., VanMorlan, A. M., Rowland, L. M., Jain, R., Haymaker, C. L., Cascio, J. A., Dhakal, M., Hoeman, C. M., Tartar, D. M. & Zaghouani, H., Aug 1 2012, In : Diabetes. 61, 8, p. 2054-2065 12 p.

Research output: Contribution to journalArticle

15 Scopus citations
2011

T cell dynamics during induction of tolerance and suppression of experimental allergic encephalomyelitis

Divekar, R. D., Haymaker, C. L., Cascio, J. A., Guloglu, B. F., Ellis, J. S., Tartar, D. M., Hoeman, C. M., Franklin, C. L., Zinselmeyer, B. H., Lynch, J. N., Miller, M. J. & Zaghouani, H., Oct 15 2011, In : Journal of Immunology. 187, 8, p. 3979-3986 8 p.

Research output: Contribution to journalArticle

11 Scopus citations
2010

APCs expressing high levels of programmed death ligand 2 sustain the development of CD4 T cell memory

Ellis, J. S., Betul Guloglu, F., Tartar, D. M., Hoeman, C. M., Haymaker, C. L., Cascio, J. A., Wan, X., Dhakal, M., VanMorlan, A., Yahng, S. H. & Zaghouani, H., Sep 15 2010, In : Journal of Immunology. 185, 6, p. 3149-3157 9 p.

Research output: Contribution to journalArticle

5 Scopus citations

FoxP3+RORγt+ T helper intermediates display suppressive function against autoimmune diabetes

Tartar, D. M., VanMorlan, A. M., Wan, X., Guloglu, F. B., Jain, R., Haymaker, C. L., Ellis, J. S., Hoeman, C. M., Cascio, J. A., Dhakal, M., Oukka, M. & Zaghouani, H., Apr 1 2010, In : Journal of Immunology. 184, 7, p. 3377-3385 9 p.

Research output: Contribution to journalArticle

61 Scopus citations

Overcoming dendritic cell tardiness to triumph over IL-13 receptor: a strategy for the development of effective pediatric vaccines.

Hoeman, C., Dhakal, M. & Zaghouani, H., Jan 1 2010, In : Discovery medicine. 9, 49, p. 554-559 6 p.

Research output: Contribution to journalArticle

4 Scopus citations
2009

Neonatal immunity: faulty T-helpers and the shortcomings of dendritic cells

Zaghouani, H., Hoeman, C. M. & Adkins, B., Dec 1 2009, In : Trends in Immunology. 30, 12, p. 585-591 7 p.

Research output: Contribution to journalReview article

165 Scopus citations
2008

Delayed maturation of an IL-12-producing dendritic cell subset explains the early Th2 bias in neonatal immunity

Lee, H. H., Hoeman, C. M., Hardaway, J. C., Guloglu, F. B., Ellis, J. S., Jain, R., Divekar, R., Tartar, D. M., Haymaker, C. L. & Zaghouani, H., Sep 29 2008, In : Journal of Experimental Medicine. 205, 10, p. 2269-2280 12 p.

Research output: Contribution to journalArticle

98 Scopus citations

Early effector T cells producing significant IFN-γ develop into memory

Bell, J. J., Ellis, J. S., Guloglu, F. B., Tartar, D. M., Lee, H. H., Divekar, R. D., Jain, R., Yu, P., Hoeman, C. M. & Zaghouani, H., Jan 1 2008, In : Journal of Immunology. 180, 1, p. 179-187 9 p.

Research output: Contribution to journalArticle

8 Scopus citations

Fetal exposure to high-avidity TCR ligand enhances expansion of peripheral T regulatory cells

Yu, P., Haymaker, C. L., Divekar, R. D., Ellis, J. S., Hardaway, J., Jain, R., Tartar, D. M., Hoeman, C. M., Cascio, J. A., Ostermeier, A. & Zaghouani, H., Jan 1 2008, In : Journal of Immunology. 181, 1, p. 73-80 8 p.

Research output: Contribution to journalArticle

14 Scopus citations

Innocuous IFNγ induced by adjuvant-free antigen restores normoglycemia in NOD mice through inhibition of IL-17 production

Jain, R., Tartar, D. M., Gregg, R. K., Divekar, R. D., Bell, J. J., Lee, H. H., Yu, P., Ellis, J. S., Hoeman, C. M., Franklin, C. L. & Zaghouani, H., Jan 21 2008, In : Journal of Experimental Medicine. 205, 1, p. 207-218 12 p.

Research output: Contribution to journalArticle

142 Scopus citations

In trans T cell tolerance diminishes autoantibody responses and exacerbates experimental allergic encephalomyelitis

Bell, J. J., Divekar, R. D., Ellis, J. S., Cascio, J. A., Haymaker, C. L., Jain, R., Tartar, D. M., Hoeman, C. M., Hardaway, J. C. & Zaghouani, H., Feb 1 2008, In : Journal of Immunology. 180, 3, p. 1508-1516 9 p.

Research output: Contribution to journalArticle

3 Scopus citations