Grants per year
Personal profile
Research Interests
My research interests focus on the neurobiological mechanism of epilepsy, examining the functional consequences of mutations in genes encoding voltage gated sodium channels. Additionally, mouse models are employed to examine underlying neurophysiological consequences epilepsy.
Education/Academic qualification
Biology, PhD, Georgia Tech
… → 2008
Research interests
- Biophysics
- Epilepsy
- Neurobiology
- Pharmacology
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Dive into the research topics where Christopher Hal Thompson is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Rescuing Neuronal Function by Gene Therapy in Alternating Hemiplegia of Childhood
George Jr., A. L. & Thompson, C. H.
3/1/21 → 12/31/21
Project: Research project
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Anticodon Edited tRNA Rescue of Nonsense SCN1A mutations
George Jr., A. L., Thompson, C. H. & Vanoye, C. G.
3/1/21 → 11/30/21
Project: Research project
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High-throughput functional evaluation of ion channel variants in epilepsy
George Jr., A. L., Thompson, C. H. & Vanoye, C. G.
National Institute of Neurological Disorders and Stroke
9/30/18 → 8/31/23
Project: Research project
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Development and investigation of murine models of channelopathy-associated epilepsy
Hawkins, N. A., Thompson, C. H. & Kearney, J. A.
National Institute of Neurological Disorders and Stroke
9/30/18 → 8/31/23
Project: Research project
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Cryptic prokaryotic promoters explain instability of recombinant neuronal sodium channels in bacteria
DeKeyser, J. M., Thompson, C. H. & George, A. L., Jan 1 2021, In: Journal of Biological Chemistry. 296, 100298.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Functional evaluation of human ion channel variants using automated electrophysiology
Vanoye, C. G., Thompson, C. H., Desai, R. R., DeKeyser, J. M., Chen, L., Rasmussen-Torvik, L. J., Welty, L. J. & George, A. L., Jan 2021, Ion Channels: Channel Chemical Biology, Engineering, and Physiological Function. Minor, D. L. & Colecraft, H. M. (eds.). Academic Press Inc, p. 383-405 23 p. (Methods in Enzymology; vol. 654).Research output: Chapter in Book/Report/Conference proceeding › Chapter
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Alternative splicing potentiates dysfunction of early-onset epileptic encephalopathy SCN2A variants
Thompson, C. H., Ben-Shalom, R., Bender, K. J. & George, A. L., Mar 2 2020, In: Journal of General Physiology. 152, 3, 201912442.Research output: Contribution to journal › Article › peer-review
Open Access8 Scopus citations -
Functional and pharmacological evaluation of a novel SCN2A variant linked to early-onset epilepsy
Adney, S. K., Millichap, J. J., DeKeyser, J. M., Abramova, T., Thompson, C. H. & George, A. L., Sep 1 2020, In: Annals of clinical and translational neurology. 7, 9, p. 1488-1501 14 p.Research output: Contribution to journal › Article › peer-review
Open Access -
SCN3A-Related Neurodevelopmental Disorder: A Spectrum of Epilepsy and Brain Malformation
Zaman, T., Helbig, K. L., Clatot, J., Thompson, C. H., Kang, S. K., Stouffs, K., Jansen, A. E., Verstraete, L., Jacquinet, A., Parrini, E., Guerrini, R., Fujiwara, Y., Miyatake, S., Ben-Zeev, B., Bassan, H., Reish, O., Marom, D., Hauser, N., Vu, T. A., Ackermann, S. & 16 others, , Aug 1 2020, In: Annals of neurology. 88, 2, p. 348-362 15 p.Research output: Contribution to journal › Article › peer-review
10 Scopus citations