Christopher Hal Thompson

  • 602 Citations
20052020

Research output per year

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Personal profile

Research Interests

My research interests focus on the neurobiological mechanism of epilepsy, examining the functional consequences of mutations in genes encoding voltage gated sodium channels. Additionally, mouse models are employed to examine underlying neurophysiological consequences epilepsy.

Education/Academic qualification

PhD, Georgia Institute of Technology

… → 2008

Research interests

  • Biophysics
  • Epilepsy
  • Neurobiology
  • Pharmacology

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Grants

  • Research Output

    • 602 Citations
    • 18 Article
    • 1 Review article

    Alternative splicing potentiates dysfunction of early-onset epileptic encephalopathy SCN2A variants

    Thompson, C. H., Ben-Shalom, R., Bender, K. J. & George, A. L., Mar 2 2020, In : Journal of General Physiology. 152, 3, 201912442.

    Research output: Contribution to journalArticle

    Open Access
  • 1 Scopus citations
    Open Access
  • 2 Scopus citations

    Direct evidence of impaired neuronal Na/K-ATPase pump function in alternating hemiplegia of childhood

    Simmons, C. Q., Thompson, C. H., Cawthon, B. E., Westlake, G., Swoboda, K. J., Kiskinis, E., Ess, K. C. & George, A. L., Jul 2018, In : Neurobiology of Disease. 115, p. 29-38 10 p.

    Research output: Contribution to journalArticle

  • 9 Scopus citations

    SCN1A variants associated with sudden infant death syndrome

    Brownstein, C. A., Goldstein, R. D., Thompson, C. H., Haynes, R. L., Giles, E., Sheidley, B., Bainbridge, M., Haas, E. A., Mena, O. J., Lucas, J., Schaber, B., Holm, I. A., George, A. L., Kinney, H. C. & Poduri, A. H., Apr 2018, In : Epilepsia. 59, 4, p. e56-e62

    Research output: Contribution to journalArticle

  • 9 Scopus citations

    The novel sodium channel modulator GS-458967 (GS967) is an effective treatment in a mouse model of SCN8A encephalopathy

    Baker, E. M., Thompson, C. H., Hawkins, N. A., Wagnon, J. L., Wengert, E. R., Patel, M. K., George, A. L., Meisler, M. H. & Kearney, J. A., Jun 2018, In : Epilepsia. 59, 6, p. 1166-1176 11 p.

    Research output: Contribution to journalArticle

  • 17 Scopus citations