Grants per year
Personal profile
Research Interests
My research interests focus on the neurobiological mechanism of epilepsy, examining the functional consequences of mutations in genes encoding voltage gated sodium channels. Additionally, mouse models are employed to examine underlying neurophysiological consequences epilepsy.
Education/Academic qualification
PhD, Georgia Institute of Technology
… → 2008
Biology, PhD, Georgia Tech
… → 2008
Research interests
- Biophysics
- Epilepsy
- Neurobiology
- Pharmacology
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Grants
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Development and investigation of murine models of channelopathy-associated epilepsy
Hawkins, N. A., Kearney, J. A. & Thompson, C. H.
National Institute of Neurological Disorders and Stroke
9/30/18 → 8/31/23
Project: Research project
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High-throughput functional evaluation of ion channel variants in epilepsy
George Jr., A. L., Thompson, C. H. & Vanoye, C. G.
National Institute of Neurological Disorders and Stroke
9/30/18 → 8/31/23
Project: Research project
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Functional Annotation of a Comprehensive Set of SCN2A Variants
George Jr., A. L. & Thompson, C. H.
Broad Institute, Inc., National Institute of Neurological Disorders and Stroke
9/15/18 → 8/31/21
Project: Research project
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Animal Models for SCN2A Neurodevelopmental Disorders
Hawkins, N. A., Kearney, J. A. & Thompson, C. H.
Office of the Director, National Institutes of Health
8/1/18 → 7/31/21
Project: Research project
Research Output
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Alternative splicing potentiates dysfunction of early-onset epileptic encephalopathy SCN2A variants
Thompson, C. H., Ben-Shalom, R., Bender, K. J. & George, A. L., Mar 2 2020, In: Journal of General Physiology. 152, 3, 201912442.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
Functional and pharmacological evaluation of a novel SCN2A variant linked to early-onset epilepsy
Adney, S. K., Millichap, J. J., DeKeyser, J. M., Abramova, T., Thompson, C. H. & George, A. L., Sep 1 2020, In: Annals of clinical and translational neurology. 7, 9, p. 1488-1501 14 p.Research output: Contribution to journal › Article › peer-review
Open Access -
SCN3A-Related Neurodevelopmental Disorder: A Spectrum of Epilepsy and Brain Malformation
Zaman, T., Helbig, K. L., Clatot, J., Thompson, C. H., Kang, S. K., Stouffs, K., Jansen, A. E., Verstraete, L., Jacquinet, A., Parrini, E., Guerrini, R., Fujiwara, Y., Miyatake, S., Ben-Zeev, B., Bassan, H., Reish, O., Marom, D., Hauser, N., Vu, T. A., Ackermann, S. & 16 others, , Aug 1 2020, In: Annals of neurology. 88, 2, p. 348-362 15 p.Research output: Contribution to journal › Article › peer-review
4 Scopus citations -
Functional consequences of a KCNT1 variant associated with status dystonicus and early-onset infantile encephalopathy
Gertler, T. S., Thompson, C. H., Vanoye, C. G., Millichap, J. J. & George, A. L., Sep 1 2019, In: Annals of clinical and translational neurology. 6, 9, p. 1606-1615 10 p.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
Direct evidence of impaired neuronal Na/K-ATPase pump function in alternating hemiplegia of childhood
Simmons, C. Q., Thompson, C. H., Cawthon, B. E., Westlake, G., Swoboda, K. J., Kiskinis, E., Ess, K. C. & George, A. L., Jul 2018, In: Neurobiology of Disease. 115, p. 29-38 10 p.Research output: Contribution to journal › Article › peer-review
9 Scopus citations