Christopher Hal Thompson

  • 563 Citations
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Personal profile

Research Interests

My research interests focus on the neurobiological mechanism of epilepsy, examining the functional consequences of mutations in genes encoding voltage gated sodium channels. Additionally, mouse models are employed to examine underlying neurophysiological consequences epilepsy.

Education/Academic qualification

PhD, Georgia Institute of Technology

… → 2008

Research interests

  • Biophysics
  • Epilepsy
  • Neurobiology
  • Pharmacology

Fingerprint Dive into the research topics where Christopher Hal Thompson is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

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Grants 2014 2023

Research Output 2005 2020

  • 563 Citations
  • 18 Article
  • 1 Review article

Alternative splicing potentiates dysfunction of early-onset epileptic encephalopathy SCN2A variants

Thompson, C. H., Ben-Shalom, R., Bender, K. J. & George, A. L., Mar 2 2020, In : The Journal of general physiology. 152, 3

Research output: Contribution to journalArticle

Open Access
Alternative Splicing
Brain Diseases
Protein Isoforms
NAV1.2 Voltage-Gated Sodium Channel
Open Access
Brain Diseases
Movement Disorders
5 Citations (Scopus)

Direct evidence of impaired neuronal Na/K-ATPase pump function in alternating hemiplegia of childhood

Simmons, C. Q., Thompson, C. H., Cawthon, B. E., Westlake, G., Swoboda, K. J., Kiskinis, E., Ess, K. C. & George, A. L., Jul 2018, In : Neurobiology of Disease. 115, p. 29-38 10 p.

Research output: Contribution to journalArticle

Induced Pluripotent Stem Cells
Membrane Potentials
Evoked Potentials
7 Citations (Scopus)

SCN1A variants associated with sudden infant death syndrome

Brownstein, C. A., Goldstein, R. D., Thompson, C. H., Haynes, R. L., Giles, E., Sheidley, B., Bainbridge, M., Haas, E. A., Mena, O. J., Lucas, J., Schaber, B., Holm, I. A., George, A. L., Kinney, H. C. & Poduri, A. H., Apr 2018, In : Epilepsia. 59, 4, p. e56-e62

Research output: Contribution to journalArticle

Sudden Infant Death
15 Citations (Scopus)

The novel sodium channel modulator GS-458967 (GS967) is an effective treatment in a mouse model of SCN8A encephalopathy

Baker, E. M., Thompson, C. H., Hawkins, N. A., Wagnon, J. L., Wengert, E. R., Patel, M. K., George, A. L., Meisler, M. H. & Kearney, J. A., Jun 2018, In : Epilepsia. 59, 6, p. 1166-1176 11 p.

Research output: Contribution to journalArticle

Sodium Channels
Brain Diseases