Keyphrases
SCN2A
97%
Nav1.2
90%
Epilepsy
83%
SCN1A
64%
Voltage-gated Sodium Channel
60%
Mouse Model
44%
Functional Consequences
44%
Chloride Channel
42%
Nav1.1
42%
Sodium Current
40%
Antiepileptic Drugs
40%
Neurodevelopmental Disorders
37%
Sodium Channel
37%
Gain-of-function
36%
Functional Assessment
35%
Patch-clamp Recording
33%
Dravet Syndrome
33%
Cystic Fibrosis Transmembrane Conductance Regulator
33%
Persistent Sodium Current
33%
Voltage Dependence
33%
Epileptic Encephalopathy
31%
Alternating Hemiplegia of childhood
31%
ClC-2 Chloride Channel
31%
Sodium Channel Modulator
31%
Scanning mutagenesis
31%
Base Editing
31%
Lamotrigine
30%
Neuronal Excitability
30%
Splice Isoforms
29%
GS967
27%
Channel Function
27%
Functional Properties
27%
Nav Channels
27%
Phenytoin
27%
Peptide Toxin
27%
Loss Function
26%
KCNQ1
25%
Developmental Encephalopathy
23%
Nav1.6
22%
Alternative Splicing
22%
Knock-in Mouse Model
21%
ATP-binding Cassette Transporter A1 (ABCA1)
21%
Neuronal Sodium Channels
21%
Autism Spectrum Disorder
20%
Neurobehavioral Phenotype
20%
Recombinant
20%
Pyramidal Neurons
20%
Epileptic
20%
Infantile Epileptic Encephalopathy
19%
SCN8A
19%
Neuroscience
Brain Disease
82%
Sodium Current
76%
Nav1.2
51%
Action Potential
42%
Anticonvulsant
42%
Sodium Channel
41%
Patch Clamp Technique
38%
Lamotrigine
35%
Sodium Channel Nav1.2
35%
Dravet Syndrome
33%
Voltage Gated Sodium Channel
31%
Neuronal Excitability
31%
Nav1.1
31%
Phenytoin
31%
Chloride Channel
31%
SCN8A
31%
Alternative Splicing
28%
Pervasive Developmental Disorder
23%
Heterologous Expression
20%
Carbamazepine
19%
Ion Channel
18%
Cystic Fibrosis Transmembrane Conductance Regulator
18%
Neurodevelopmental Disorder
18%
Tetrodotoxin
18%
Electrophysiology
17%
Excitability
15%
Behavioral Effect
15%
Hemiplegia
15%
Status Dystonicus
15%
SCN3A
15%
Adenosine Triphosphatase (Potassium Sodium)
15%
Myoclonic Epilepsy
15%
Ion Permeability
15%
KCNB1
15%
Interneuron
15%
Exome Sequencing
15%
Gene Expression System
15%
KCNT1
15%
Protein Kinases
15%
Atrial Fibrillation
15%
Calmodulin
15%
Autism
15%
Sodium Channel Blocker
12%
Familial Atrial Fibrillation
10%
Cardiac Dysrhythmia
10%
Patch Clamp
10%
Electroencephalogram
10%
In Vitro
10%
Channelopathy
9%
Voltage Clamp
9%
Biochemistry, Genetics and Molecular Biology
Electric Potential
100%
Nav1.2
85%
Sodium Channel
63%
Isoform
58%
Wild Type
34%
Patch Clamp Technique
32%
Exome Sequencing
31%
Cystic Fibrosis Transmembrane Conductance Regulator
31%
Channelopathy
22%
Alternative Splicing
22%
Ion Channel
21%
Mouse Model
18%
ABC Transporter
18%
ATP-binding Cassette Transporter
18%
Automated Patch Clamp
18%
Chloride Channel
16%
Mental Retardation
16%
Genetics
16%
Functional Divergence
15%
Mutagenesis
15%
ATP1A3
15%
Nav1.1
15%
Promoter Region
15%
Drug Response
15%
Knockout Mouse
15%
Genetic Evaluation
15%
Heterologous Expression
15%
SCN3A
15%
Evolution
15%
Sodium Current
15%
Gene Expression System
15%
KCNB1
15%
Electrophysiology
15%
SCN8A
15%
Atrial Fibrillation
15%
Missense
13%
Genetic Divergence
12%
Whole Cell
12%
Voltage Clamp
12%
Guide RNA
12%
Plasmid
11%
Whole Cell Patch Clamp
11%
Genotyping
10%
Action Potential
10%
Adenosine Triphosphate
10%
Excitability
9%
Action Potential Duration
9%
KCNE1
9%
Steady State
8%
Complementary DNA
7%