Keyphrases
Alternating Hemiplegia of childhood
24%
Alternative Splicing
17%
Antiepileptic Drugs
31%
ATP-binding Cassette Transporter A1 (ABCA1)
16%
Autism Spectrum Disorder
16%
Base Editing
24%
Channel Function
27%
Chloride Channel
33%
ClC-2 Chloride Channel
24%
Cystic Fibrosis Transmembrane Conductance Regulator
25%
Developmental Encephalopathy
19%
Dravet Syndrome
25%
Epilepsy
82%
Epileptic Encephalopathy
26%
Functional Assessment
27%
Functional Consequences
36%
Functional Properties
23%
Gain-of-function
33%
Gain-of-function mutation
21%
GS967
21%
KCNQ1
20%
Knock-in Mouse Model
16%
Lamotrigine
23%
Loss Function
31%
Malformations of Cortical Development
21%
Mouse Model
34%
Nav Channels
21%
Nav1.1
35%
Nav1.2
76%
Nav1.6
17%
Neurobehavioral Phenotype
16%
Neurodevelopmental Disorders
30%
Neuronal Excitability
23%
Neuronal Sodium Channels
16%
Patch-clamp Recording
30%
Peptide Toxin
21%
Persistent Sodium Current
25%
Phenytoin
21%
Pyramidal Neurons
17%
Scanning mutagenesis
24%
SCN1A
61%
SCN2A
100%
Seizure
16%
Sodium Channel
28%
Sodium Channel Modulator
24%
Sodium Current
33%
Splice Isoforms
22%
Variant Function
24%
Voltage Dependence
25%
Voltage-gated Sodium Channel
48%
Neuroscience
Action Potential
33%
Adenosine Triphosphatase (Potassium Sodium)
12%
Alternative Splicing
21%
Anticonvulsant
33%
Atrial Fibrillation
12%
Autism
12%
Behavioral Effect
12%
Brain Disease
64%
Calmodulin
12%
Carbamazepine
15%
Cardiac Dysrhythmia
8%
Channelopathy
7%
Chloride Channel
24%
Cystic Fibrosis Transmembrane Conductance Regulator
14%
Dravet Syndrome
26%
Electroencephalogram
8%
Electrophysiology
13%
Excitability
12%
Exome Sequencing
12%
Familial Atrial Fibrillation
8%
Gene Expression System
12%
Hemiplegia
12%
Heterologous Expression
16%
In Vitro
8%
Interneuron
18%
Ion Channel
14%
Ion Permeability
12%
KCNB1
12%
KCNT1
12%
Lamotrigine
27%
Myoclonic Epilepsy
12%
Nav1.1
30%
Nav1.2
40%
Neurodevelopmental Disorder
14%
Neuronal Excitability
24%
Patch Clamp
8%
Patch Clamp Technique
41%
Pervasive Developmental Disorder
18%
Phenytoin
24%
Protein Kinases
12%
SCN3A
12%
SCN8A
24%
Sodium Channel
32%
Sodium Channel Blocker
10%
Sodium Channel Nav1.2
27%
Sodium Current
65%
Status Dystonicus
12%
Tetrodotoxin
14%
Voltage Clamp
7%
Voltage Gated Sodium Channel
24%
Biochemistry, Genetics and Molecular Biology
ABC Transporter
14%
Action Potential
8%
Action Potential Duration
7%
Adenosine Triphosphate
8%
Allele
8%
Alternative Splicing
17%
ATP-binding Cassette Transporter
14%
ATP1A3
12%
Atrial Fibrillation
12%
Automated Patch Clamp
22%
Channelopathy
17%
Chloride Channel
13%
Cystic Fibrosis Transmembrane Conductance Regulator
24%
Drug Response
12%
Electric Potential
77%
Electrophysiology
12%
Excitability
7%
Exome Sequencing
24%
Functional Divergence
12%
Gene Expression System
12%
Genetic Divergence
10%
Genetic Evaluation
12%
Genetic Screening
15%
Genetics
16%
Genotyping
20%
Guide RNA
9%
Heterologous Expression
12%
Interneuron
8%
Ion Channel
16%
Isoform
45%
KCNB1
12%
KCNE1
7%
Knockout Mouse
12%
Mental Retardation
12%
Missense
10%
Mouse Model
14%
Mutagenesis
12%
Nav1.1
16%
Nav1.2
66%
Patch Clamp Technique
33%
Plasmid
9%
Promoter Region
12%
SCN3A
12%
SCN8A
12%
Sodium Channel
49%
Sodium Current
16%
Voltage Clamp
9%
Whole Cell
9%
Whole Cell Patch Clamp
9%
Wild Type
26%