Grants per year
Search results
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Finished
Effects of XPC-5462, NBI921353, NBI921354, and NBI921355 on SCN2A (NaV1.2) gain-of-function (GOF) variants (hereinafter "Project")
George, A. L. (PD/PI) & Thompson, C. H. (Co-Investigator)
3/28/22 → 3/31/23
Project: Research project
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Effects of PRAX-562 on sodium current and excitability of neurons from a Scn2aQ54 gain-of-function mouse
George, A. L. (PD/PI), Kearney, J. A. (Co-Investigator) & Thompson, C. H. (Co-Investigator)
Praxis Precision Medicines, Inc.
10/13/21 → 9/30/22
Project: Research project
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Rescuing Neuronal Function by Gene Therapy in Alternating Hemiplegia of Childhood
George, A. L. (PD/PI), Thompson, C. H. (Co-Investigator) & Simmons, C. (Other)
3/1/21 → 6/30/22
Project: Research project
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Anticodon Edited tRNA Rescue of Nonsense SCN1A mutations
George, A. L. (PD/PI), Thompson, C. H. (Co-Investigator) & Vanoye, C. G. (Co-Investigator)
3/1/21 → 6/30/22
Project: Research project
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Tandem Genetically Encoded Voltage and Calcium Indicator Mice for Optical Physiology of Excitable Cells
Thompson, C. H. (PD/PI)
Office of the Director, National Institutes of Health
2/1/19 → 7/31/23
Project: Research project
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Functional Annotation of a Comprehensive Set of SCN2A Variants
George, A. L. (PD/PI) & Thompson, C. H. (Co-Investigator)
Broad Institute, Inc., National Institute of Neurological Disorders and Stroke
9/15/18 → 8/31/22
Project: Research project
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Animal Models for SCN2A Neurodevelopmental Disorders
Kearney, J. A. (PD/PI), Hawkins, N. A. (Co-Investigator) & Thompson, C. H. (Co-Investigator)
Office of the Director, National Institutes of Health
8/1/18 → 1/31/22
Project: Research project
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Molecular Physiology and Pharmacology of ATP1A3 Mutations
George, A. L. (PD/PI) & Thompson, C. H. (Co-Investigator)
Alternating Hemiplegia of Childhood Foundation
7/1/18 → 5/31/22
Project: Research project
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Molecular Physiology and Pharmacology of ATP1A3 Mutations in AHC
George, A. L. (PD/PI) & Thompson, C. H. (Co-Investigator)
Alternating Hemiplegia of Childhood Foundation
7/1/17 → 6/30/18
Project: Research project
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High Throughput Functional Annotation of Human SCN2A Variants
George, A. L. (PD/PI) & Thompson, C. H. (Co-Investigator)
1/1/17 → 12/31/17
Project: Research project
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Modulation of Dravet Syndrome by Nedd4-2
Kearney, J. A. (PD/PI), Hawkins, N. A. (Other) & Thompson, C. H. (Other)
4/12/16 → 4/12/17
Project: Research project
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Novel Pharmacological Therapy for Dravet Syndrome
George, A. L. (PD/PI), Kearney, J. A. (Co-Investigator) & Thompson, C. H. (Co-Investigator)
Dravet Syndrome Foundation, Inc.
1/1/15 → 12/31/16
Project: Research project
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Efficacy of Selective Sodium Channel Block in Dravet Syndrome
George, A. L. (PD/PI), Contractor, A. (Co-Investigator), Kearney, J. A. (Co-Investigator) & Thompson, C. H. (Co-Investigator)
12/3/14 → 4/3/16
Project: Research project
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Genetic Modifiers of Childhood Epilepsy
Kearney, J. A. (PD/PI), George, A. L. (Co-Investigator) & Thompson, C. H. (Other)
National Institute of Neurological Disorders and Stroke
9/1/14 → 6/30/20
Project: Research project
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Molecular Physiology and Pharmacology of ATP1A3 Mutations in AHC
George, A. L. (PD/PI) & Thompson, C. H. (Co-Investigator)
Vanderbilt University, Alternating Hemiplegia of Childhood Foundation
7/1/14 → 6/30/17
Project: Research project