Grants per year
Personal profile
Research Interests
My research focuses on the immune function of major histocompatibility complex (MHC) class Ib molecules in normal and diseased states. My lab is interested in understanding how MHC class Ib-restricted T cells are selected and regulated during development and how they contribute to the control of autoimmunity, anti-tumor immunity and infectious diseases. My lab is also interested in identifying microbial antigens recognized by MHC class Ib-restricted T cells with the goal of developing new T cell-based vaccines for microbial infection.
Education/Academic qualification
PhD, University of Texas
… → 1987
Keywords
- Autoimmunity
- Cancer Biology
- Immune Regulation
- Immune System
- Infectious Diseases
- Inflammatory Bowel Disease
- Vaccine-preventable Illnesses
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Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Grants 2008 2023
The role of non-classical MHC class I molecules in immune responses to Mycobacterium tuberculosis infection
National Institute of Allergy and Infectious Diseases
5/14/18 → 4/30/23
Project: Research project
Mycobacterium Infections
Mycobacterium tuberculosis
T-Lymphocytes
NK Cell Lectin-Like Receptor Subfamily C
Vaccination
Development of Lipid-based Nanoparticle Vaccines Against Mycobacterium tuberculosis
National Institute of Allergy and Infectious Diseases
1/25/17 → 12/31/19
Project: Research project
Mycolic Acids
Mycobacterium tuberculosis
Nanoparticles
Vaccines
Lipids
HIV and Mycobacterial Disease in Mali
Achenbach, C. J., Maiga, M., Murphy, R. L. & Wang, C.
John E. Fogarty International Center for Advanced Study in the Health Sciences
4/9/16 → 2/28/21
Project: Research project
Mali
HIV
Research
National Institute of Allergy and Infectious Diseases (U.S.)
Mycobacterium
The Role of Group 1 CD1-restricted T Cells in Infectious Disease
National Institute of Allergy and Infectious Diseases
2/1/16 → 1/31/21
Project: Research project
Communicable Diseases
T-Lymphocytes
Mycobacterium tuberculosis
Mycobacterium Infections
Lipids
The regulation and function of CD1d-restricted T cells
National Institute of Allergy and Infectious Diseases
6/11/14 → 5/31/19
Project: Research project
Natural Killer T-Cells
T-Lymphocytes
T-Lymphocyte Subsets
Galactosylceramides
Research Output 1987 2018
1
Citation
(Scopus)
Induction of mycobacterium tuberculosislipid-specific t cell responses by pulmonary delivery of mycolic acid-loaded polymeric micellar nanocarriers
Shang, S., Kats, D., Cao, L., Morgun, E., Velluto, D., He, Y., Xu, Q., Wang, C-R. & Scott, E. A., Nov 27 2018, In : Frontiers in immunology. 9, NOV, 02709.Research output: Contribution to journal › Article
Mycolic Acids
Mycobacterium
Lung
T-Lymphocytes
Mycobacterium tuberculosis
1
Citation
(Scopus)
Linking CD1-restricted T cells with autoimmunity and dyslipidemia: Lipid levels matter
Bagchi, S., Genardi, S. & Wang, C-R., Jul 16 2018, In : Frontiers in immunology. 9, JUL, 1616.Research output: Contribution to journal › Review article
Dyslipidemias
Autoimmunity
T-Lymphocytes
Lipids
Autoimmune Diseases
33
Citations
(Scopus)
Non-classical Immunity Controls Microbiota Impact on Skin Immunity and Tissue Repair
Linehan, J. L., Harrison, O. J., Han, S. J., Byrd, A. L., Vujkovic-Cvijin, I., Villarino, A. V., Sen, S. K., Shaik, J., Smelkinson, M., Tamoutounour, S., Collins, N., Bouladoux, N., Dzutsev, A., Rosshart, S. P., Arbuckle, J. H., Wang, C-R., Kristie, T. M., Rehermann, B., Trinchieri, G., Brenchley, J. M. & 2 others, Feb 8 2018, In : Cell. 172, 4, p. 784-796.e18Research output: Contribution to journal › Article
Microbiota
Immunity
Skin
Repair
T-cells
18
Citations
(Scopus)
CD1b-autoreactive T cells contribute to hyperlipidemia-induced skin inflammation in mice
Bagchi, S., He, Y., Zhang, H., Cao, L., Rhijn, I. V., Moody, D. B., Gudjonsson, J. E. & Wang, C-R., Jun 1 2017, In : Journal of Clinical Investigation. 127, 6, p. 2339-2352 14 p.Research output: Contribution to journal › Article
Hyperlipidemias
Inflammation
T-Lymphocytes
Skin
Apolipoproteins E
8
Citations
(Scopus)
Crosstalk between type II NKT cells and T cells leads to spontaneous chronic inflammatory liver disease
Weng, X., He, Y., Visvabharathy, L., Liao, C. M., Tan, X., Balakumar, A. & Wang, C-R., Oct 1 2017, In : Journal of Hepatology. 67, 4, p. 791-800 10 p.Research output: Contribution to journal › Article
Natural Killer T-Cells
Liver Diseases
T-Lymphocytes
Autoimmune Hepatitis
Liver