If you made any changes in Pure, your changes will be visible here soon.

Personal profile

Research Interests

My research focuses on the immune function of major histocompatibility complex (MHC) class Ib molecules in normal and diseased states. My lab is interested in understanding how MHC class Ib-restricted T cells are selected and regulated during development and how they contribute to the control of autoimmunity, anti-tumor immunity and infectious diseases. My lab is also interested in identifying microbial antigens recognized by MHC class Ib-restricted T cells with the goal of developing new T cell-based vaccines for microbial infection.

Education/Academic qualification

PhD, University of Texas

… → 1987

Keywords

  • Autoimmunity
  • Cancer Biology
  • Immune Regulation
  • Immune System
  • Infectious Diseases
  • Inflammatory Bowel Disease
  • Vaccine-preventable Illnesses

Fingerprint Fingerprint is based on mining the text of the experts' scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

  • 2 Similar Profiles
Natural Killer T-Cells Medicine & Life Sciences
T-Lymphocytes Medicine & Life Sciences
T-cells Chemical Compounds
Major Histocompatibility Complex Medicine & Life Sciences
Natural Killer Cells Medicine & Life Sciences
Peptides Medicine & Life Sciences
CD1d Antigen Medicine & Life Sciences
Listeria monocytogenes Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Grants 2008 2023

Mycobacterium Infections
Mycobacterium tuberculosis
T-Lymphocytes
NK Cell Lectin-Like Receptor Subfamily C
Vaccination
Mycolic Acids
Mycobacterium tuberculosis
Nanoparticles
Vaccines
Lipids
Mali
HIV
Research
National Institute of Allergy and Infectious Diseases (U.S.)
Mycobacterium
Communicable Diseases
T-Lymphocytes
Mycobacterium tuberculosis
Mycobacterium Infections
Lipids
Natural Killer T-Cells
T-Lymphocytes
T-Lymphocyte Subsets
Galactosylceramides

Research Output 1987 2018

  • 7215 Citations
  • 91 Article
  • 5 Review article
  • 1 Comment/debate
  • 1 Short survey
1 Citation (Scopus)

Induction of mycobacterium tuberculosislipid-specific t cell responses by pulmonary delivery of mycolic acid-loaded polymeric micellar nanocarriers

Shang, S., Kats, D., Cao, L., Morgun, E., Velluto, D., He, Y., Xu, Q., Wang, C-R. & Scott, E. A., Nov 27 2018, In : Frontiers in immunology. 9, NOV, 02709.

Research output: Contribution to journalArticle

Mycolic Acids
Mycobacterium
Lung
T-Lymphocytes
Mycobacterium tuberculosis
1 Citation (Scopus)

Linking CD1-restricted T cells with autoimmunity and dyslipidemia: Lipid levels matter

Bagchi, S., Genardi, S. & Wang, C-R., Jul 16 2018, In : Frontiers in immunology. 9, JUL, 1616.

Research output: Contribution to journalReview article

Dyslipidemias
Autoimmunity
T-Lymphocytes
Lipids
Autoimmune Diseases
33 Citations (Scopus)

Non-classical Immunity Controls Microbiota Impact on Skin Immunity and Tissue Repair

Linehan, J. L., Harrison, O. J., Han, S. J., Byrd, A. L., Vujkovic-Cvijin, I., Villarino, A. V., Sen, S. K., Shaik, J., Smelkinson, M., Tamoutounour, S., Collins, N., Bouladoux, N., Dzutsev, A., Rosshart, S. P., Arbuckle, J. H., Wang, C-R., Kristie, T. M., Rehermann, B., Trinchieri, G., Brenchley, J. M. & 2 othersO'Shea, J. J. & Belkaid, Y., Feb 8 2018, In : Cell. 172, 4, p. 784-796.e18

Research output: Contribution to journalArticle

Microbiota
Immunity
Skin
Repair
T-cells
18 Citations (Scopus)

CD1b-autoreactive T cells contribute to hyperlipidemia-induced skin inflammation in mice

Bagchi, S., He, Y., Zhang, H., Cao, L., Rhijn, I. V., Moody, D. B., Gudjonsson, J. E. & Wang, C-R., Jun 1 2017, In : Journal of Clinical Investigation. 127, 6, p. 2339-2352 14 p.

Research output: Contribution to journalArticle

Hyperlipidemias
Inflammation
T-Lymphocytes
Skin
Apolipoproteins E
8 Citations (Scopus)

Crosstalk between type II NKT cells and T cells leads to spontaneous chronic inflammatory liver disease

Weng, X., He, Y., Visvabharathy, L., Liao, C. M., Tan, X., Balakumar, A. & Wang, C-R., Oct 1 2017, In : Journal of Hepatology. 67, 4, p. 791-800 10 p.

Research output: Contribution to journalArticle

Natural Killer T-Cells
Liver Diseases
T-Lymphocytes
Autoimmune Hepatitis
Liver