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Personal profile

Research Interests

My research focuses on the immune function of major histocompatibility complex (MHC) class Ib molecules in normal and diseased states. My lab is interested in understanding how MHC class Ib-restricted T cells are selected and regulated during development and how they contribute to the control of autoimmunity, anti-tumor immunity and infectious diseases. My lab is also interested in identifying microbial antigens recognized by MHC class Ib-restricted T cells with the goal of developing new T cell-based vaccines for microbial infection.

Education/Academic qualification

PhD, University of Texas

… → 1987

Research interests

  • Autoimmunity
  • Cancer Biology
  • Immune Regulation
  • Immune System
  • Infectious Diseases
  • Inflammatory Bowel Disease
  • Vaccine-preventable Illnesses

Fingerprint Dive into the research topics where Chyung-Ru Wang is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 3 Similar Profiles
Natural Killer T-Cells Medicine & Life Sciences
T-Lymphocytes Medicine & Life Sciences
T-cells Chemical Compounds
Major Histocompatibility Complex Medicine & Life Sciences
Natural Killer Cells Medicine & Life Sciences
Peptides Medicine & Life Sciences
CD1d Antigen Medicine & Life Sciences
Listeria monocytogenes Medicine & Life Sciences

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Grants 2008 2023

Mycobacterium Infections
Mycobacterium tuberculosis
T-Lymphocytes
NK Cell Lectin-Like Receptor Subfamily C
Vaccination
Mycolic Acids
Mycobacterium tuberculosis
Nanoparticles
Vaccines
Lipids
Mali
HIV
Research
National Institute of Allergy and Infectious Diseases (U.S.)
Mycobacterium
Communicable Diseases
T-Lymphocytes
Mycobacterium tuberculosis
Mycobacterium Infections
Lipids

Research Output 1987 2019

  • 7358 Citations
  • 92 Article
  • 5 Review article
  • 1 Comment/debate
  • 1 Short survey
Open Access
lipid metabolism
arteriosclerosis
Natural Killer T-Cells
T-cells
Lipid Metabolism
3 Citations (Scopus)

Induction of mycobacterium tuberculosislipid-specific t cell responses by pulmonary delivery of mycolic acid-loaded polymeric micellar nanocarriers

Shang, S., Kats, D., Cao, L., Morgun, E., Velluto, D., He, Y., Xu, Q., Wang, C-R. & Scott, E. A., Nov 27 2018, In : Frontiers in immunology. 9, NOV, 02709.

Research output: Contribution to journalArticle

Mycolic Acids
Mycobacterium
Lung
T-Lymphocytes
Mycobacterium tuberculosis
1 Citation (Scopus)

Linking CD1-restricted T cells with autoimmunity and dyslipidemia: Lipid levels matter

Bagchi, S., Genardi, S. & Wang, C-R., Jul 16 2018, In : Frontiers in immunology. 9, JUL, 1616.

Research output: Contribution to journalReview article

Dyslipidemias
Autoimmunity
T-Lymphocytes
Lipids
Autoimmune Diseases
52 Citations (Scopus)

Non-classical Immunity Controls Microbiota Impact on Skin Immunity and Tissue Repair

Linehan, J. L., Harrison, O. J., Han, S. J., Byrd, A. L., Vujkovic-Cvijin, I., Villarino, A. V., Sen, S. K., Shaik, J., Smelkinson, M., Tamoutounour, S., Collins, N., Bouladoux, N., Dzutsev, A., Rosshart, S. P., Arbuckle, J. H., Wang, C-R., Kristie, T. M., Rehermann, B., Trinchieri, G., Brenchley, J. M. & 2 others, O'Shea, J. J. & Belkaid, Y., Feb 8 2018, In : Cell. 172, 4, p. 784-796.e18

Research output: Contribution to journalArticle

Microbiota
Immunity
Skin
Repair
T-cells
21 Citations (Scopus)

CD1b-autoreactive T cells contribute to hyperlipidemia-induced skin inflammation in mice

Bagchi, S., He, Y., Zhang, H., Cao, L., Rhijn, I. V., Moody, D. B., Gudjonsson, J. E. & Wang, C-R., Jun 1 2017, In : Journal of Clinical Investigation. 127, 6, p. 2339-2352 14 p.

Research output: Contribution to journalArticle

Hyperlipidemias
Inflammation
T-Lymphocytes
Skin
Apolipoproteins E