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Chyung-Ru Wang

  • 7640 Citations
1987 …2020

Research output per year

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Personal profile

Research Interests

My research focuses on the immune function of major histocompatibility complex (MHC) class Ib molecules in normal and diseased states. My lab is interested in understanding how MHC class Ib-restricted T cells are selected and regulated during development and how they contribute to the control of autoimmunity, anti-tumor immunity and infectious diseases. My lab is also interested in identifying microbial antigens recognized by MHC class Ib-restricted T cells with the goal of developing new T cell-based vaccines for microbial infection.

Education/Academic qualification

PhD, University of Texas

… → 1987

Research interests

  • Autoimmunity
  • Cancer Biology
  • Immune Regulation
  • Immune System
  • Infectious Diseases
  • Inflammatory Bowel Disease
  • Vaccine-preventable Illnesses

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Grants

Design and characterization of biomimetic nanobiomaterials to elicit CD1-restricted T cell responses during sub-unit vaccination

Wang, C.

National Institute of Allergy and Infectious Diseases

8/1/19 → 7/31/23

Project: Research project

    • The role of non-classical MHC class I molecules in immune responses to Mycobacterium tuberculosis infection

    Wang, C. & Bartom, E. T.

    National Institute of Allergy and Infectious Diseases

    5/14/18 → 4/30/23

    Project: Research project

    • HIV and Mycobacterial Disease in Mali

    Achenbach, C. J., Maiga, M., Murphy, R. L. & Wang, C.

    John E. Fogarty International Center for Advanced Study in the Health Sciences

    4/9/16 → 2/28/21

    Project: Research project

    • The Role of Group 1 CD1-restricted T Cells in Infectious Disease

    Wang, C.

    National Institute of Allergy and Infectious Diseases

    2/1/16 → 1/31/21

    Project: Research project

    • Development of Lipid-based Nanoparticle Vaccines Against Mycobacterium tuberculosis

    Scott, E. A. & Wang, C.

    National Institute of Allergy and Infectious Diseases

    1/25/17 → 12/31/19

    Project: Research project

    • Research Output

    • 7640 Citations
    • 94 Article
    • 5 Review article
    • 1 Comment/debate
    • 1 Short survey

    Group 1 CD1-restricted T cells contribute to control of systemic Staphylococcus aureus infection

    Visvabharathy, L., Genardi, S., Cao, L., He, Y., Alonzo, F., Berdyshev, E. & Wang, C. R., Apr 2020, In : PLoS pathogens. 16, 4, e1008443.

    Research output: Contribution to journal › Article

    Open Access

    • USP22 controls iNKT immunity through MED1 suppression of histone H2A monoubiquitination

    Zhang, Y., Wang, Y., Gao, B., Sun, Y., Cao, L., Genardi, S. M., Wang, C. R., Li, H. B., Sun, Z., Yang, Y. & Fang, D., May 4 2020, In : Journal of Experimental Medicine. 217, 5, e20182218.

    Research output: Contribution to journal › Article

    Open Access

    • Invariant natural killer T-cells and total cd1d restricted cells differentially influence lipid metabolism and atherosclerosis in low density receptor deficient mice

    VanderLaan, P. A., Reardon, C. A., Cabana, V. G., Wang, C. R. & Getz, G. S., Sep 2 2019, In : International journal of molecular sciences. 20, 18, 4566.

    Research output: Contribution to journal › Article

    Open Access

    • Induction of mycobacterium tuberculosislipid-specific t cell responses by pulmonary delivery of mycolic acid-loaded polymeric micellar nanocarriers

    Shang, S., Kats, D., Cao, L., Morgun, E., Velluto, D., He, Y., Xu, Q., Wang, C. R. & Scott, E. A., Nov 27 2018, In : Frontiers in immunology. 9, NOV, 02709.

    Research output: Contribution to journal › Article

    • 6 Scopus citations

    Linking CD1-restricted T cells with autoimmunity and dyslipidemia: Lipid levels matter

    Bagchi, S., Genardi, S. & Wang, C. R., Jul 16 2018, In : Frontiers in immunology. 9, JUL, 1616.

    Research output: Contribution to journal › Review article

    • 2 Scopus citations