Grants per year
Personal profile
Research Interests
My research focuses on the immune function of major histocompatibility complex (MHC) class Ib molecules in normal and diseased states. My lab is interested in understanding how MHC class Ib-restricted T cells are selected and regulated during development and how they contribute to the control of autoimmunity, anti-tumor immunity and infectious diseases. My lab is also interested in identifying microbial antigens recognized by MHC class Ib-restricted T cells with the goal of developing new T cell-based vaccines for microbial infection.
Education/Academic qualification
PhD, University of Texas
… → 1987
Research interests
- Autoimmunity
- Cancer Biology
- Immune Regulation
- Immune System
- Infectious Diseases
- Inflammatory Bowel Disease
- Vaccine-preventable Illnesses
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Grants
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The Role of Lipid-specific T cells in Mediating Protection Against M. tuberculosis
University of Washington, National Institute of Allergy and Infectious Diseases
6/1/20 → 5/31/25
Project: Research project
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HIV and Mycobacterial Disease in Mali
Achenbach, C. J., Maiga, M., Murphy, R. L. & Wang, C.
John E. Fogarty International Center for Advanced Study in the Health Sciences
4/9/16 → 2/28/21
Project: Research project
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The Role of Group 1 CD1-restricted T Cells in Infectious Disease
National Institute of Allergy and Infectious Diseases
2/1/16 → 1/31/22
Project: Research project
Research Output
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Group 1 CD1-restricted T cells contribute to control of systemic Staphylococcus aureus infection
Visvabharathy, L., Genardi, S., Cao, L., He, Y., Alonzo, F., Berdyshev, E. & Wang, C. R., Apr 2020, In: PLoS pathogens. 16, 4, e1008443.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
USP22 controls iNKT immunity through MED1 suppression of histone H2A monoubiquitination
Zhang, Y., Wang, Y., Gao, B., Sun, Y., Cao, L., Genardi, S. M., Wang, C. R., Li, H. B., Sun, Z., Yang, Y. & Fang, D., May 4 2020, In: Journal of Experimental Medicine. 217, 5, e20182218.Research output: Contribution to journal › Article › peer-review
Open Access -
Invariant natural killer T-cells and total cd1d restricted cells differentially influence lipid metabolism and atherosclerosis in low density receptor deficient mice
VanderLaan, P. A., Reardon, C. A., Cabana, V. G., Wang, C. R. & Getz, G. S., Sep 2 2019, In: International journal of molecular sciences. 20, 18, 4566.Research output: Contribution to journal › Article › peer-review
Open Access -
Induction of mycobacterium tuberculosislipid-specific t cell responses by pulmonary delivery of mycolic acid-loaded polymeric micellar nanocarriers
Shang, S., Kats, D., Cao, L., Morgun, E., Velluto, D., He, Y., Xu, Q., Wang, C. R. & Scott, E. A., Nov 27 2018, In: Frontiers in immunology. 9, NOV, 2709.Research output: Contribution to journal › Article › peer-review
11 Scopus citations -
Linking CD1-restricted T cells with autoimmunity and dyslipidemia: Lipid levels matter
Bagchi, S., Genardi, S. & Wang, C. R., Jul 16 2018, In: Frontiers in immunology. 9, JUL, 1616.Research output: Contribution to journal › Review article › peer-review
4 Scopus citations