Grants per year
Personal profile
Research Interests
Nanotechnology is the study of the fabrication, directed self-assembly, and characterization of materials that have size dimensions between 1 and 100 nanometers. In the context of biological nanostructures, this is the size regime of the molecular machinery that constitutes, for example, functional viruses, bacteria, and human cells. The challenge of bio-nanotechnology and the focus of our lab is to control the synthesis of structures that naturally interface with biological systems to develop exquisitely targeted, practical, safe, and effective nanoparticle therapeutics, imaging agents, and biosensors.
Education/Academic qualification
PhD, Northwestern University, Feinberg School of Medicine
… → 2007
MD, Northwestern University, Feinberg School of Medicine
… → 2004
Research interests
- Atherosclerosis
- Bioengineering
- Cancer Biology
- Nanotechnology
- Radiology
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Grants
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The role of A-to-I RNA editing in advanced prostate cancer
U.S. Army Medical Research and Materiel Command
9/30/19 → 9/29/22
Project: Research project
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The Role of MicroRNAs in Corneal Epithelial Homeostasis
Batlle, D., Lavker, R. M., Peng, H. & Thaxton, C. S.
Kennedy Institute - National Eye Clinic
7/1/19 → 7/31/23
Project: Research project
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Highly Functional Organic Core Templated High-Density Lipoproteins to Reverse Vascular Disease
Dementieva, I. S., Nguyen, S. & Thaxton, C. S.
4/1/19 → 12/31/21
Project: Research project
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Lipoteichoic acid mediated immune modulation of chronic pain
Murphy, S. F., Schaeffer, A. J., Thaxton, C. S. & Thumbikat, P.
National Institute of Diabetes and Digestive and Kidney Diseases
8/1/16 → 7/31/21
Project: Research project
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Thaxton - Synthetic, Bioprogrammable Lipid and Lipoprotein Particles for Phospolid and Cholesterol Metabolism
Schatz, G. C., Thaxton, C. S. & Thaxton, C. S.
6/8/15 → 6/7/21
Project: Research project
Research Output
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Interparticle Molecular Exchange of Surface Chemical Components of Native High-Density Lipoproteins to Complementary Nanoparticle Scaffolds
McMahon, K. M., Calvert, A. E., Dementieva, I. S., Hussain, S., Wilkins, J. T. & Thaxton, C. S., Oct 23 2020, In: ACS Sensors. 5, 10, p. 3019-3024 6 p.Research output: Contribution to journal › Article › peer-review
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Tri-ethylene glycol modified class B and class C CpG conjugated gold nanoparticles for the treatment of lymphoma
Lin, A. Y., Rink, J. S., Karmali, R., Xu, J., Kocherginsky, M., Thaxton, C. S. & Gordon, L. I., Nov 2020, In: Nanomedicine: Nanotechnology, Biology, and Medicine. 30, 102290.Research output: Contribution to journal › Article › peer-review
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An update on synthetic high-density lipoprotein-like nanoparticles for cancer therapy
Henrich, S. E. & Thaxton, C. S., Jun 3 2019, In: Expert review of anticancer therapy. 19, 6, p. 515-528 14 p.Research output: Contribution to journal › Review article › peer-review
3 Scopus citations -
Biomimetic Magnetic Nanostructures: A Theranostic Platform Targeting Lipid Metabolism and Immune Response in Lymphoma
Singh, A., Nandwana, V., Rink, J. S., Ryoo, S. R., Chen, T. H., Allen, S. D., Scott, E. A., Gordon, L. I., Thaxton, C. S. & Dravid, V. P., Sep 24 2019, In: ACS nano. 13, 9, p. 10301-10311 11 p.Research output: Contribution to journal › Article › peer-review
3 Scopus citations -
Supramolecular Assembly of High-Density Lipoprotein Mimetic Nanoparticles Using Lipid-Conjugated Core Scaffolds
Henrich, S. E., Hong, B. J., Rink, J. S., Nguyen, S. B. T. & Thaxton, C. S., Jun 26 2019, In: Journal of the American Chemical Society. 141, 25, p. 9753-9757 5 p.Research output: Contribution to journal › Article › peer-review
6 Scopus citations