Grants per year
Personal profile
Research Interests
Nanotechnology is the study of the fabrication, directed self-assembly, and characterization of materials that have size dimensions between 1 and 100 nanometers. In the context of biological nanostructures, this is the size regime of the molecular machinery that constitutes, for example, functional viruses, bacteria, and human cells. The challenge of bio-nanotechnology and the focus of our lab is to control the synthesis of structures that naturally interface with biological systems to develop exquisitely targeted, practical, safe, and effective nanoparticle therapeutics, imaging agents, and biosensors.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
PhD, Northwestern University Feinberg School of Medicine
… → 2007
Medicine, MD, Northwestern University Feinberg School of Medicine
… → 2004
Research interests keywords
- Atherosclerosis
- Bioengineering
- Cancer Biology
- Nanotechnology
- Radiology
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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P&F Colby Thaxton: High-Density Lipoprotein Receptor Expression and Targeting in Inflammatory Skin Disease
Thaxton, C. S. (Co-Investigator)
National Institute of Arthritis and Musculoskeletal and Skin Diseases
8/1/24 → 6/30/29
Project: Research project
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Liquid Biopsy to Measure Novel Biomarkers of ImmunoMetabolic Cancer Risk (IMCR)
Thaxton, C. S. (PD/PI), Thaxton, C. S. (PD/PI), Abaza, Y. (Co-Investigator), Abaza, Y. (Co-Investigator), Altman, J. K. (Co-Investigator), Altman, J. K. (Co-Investigator), Behdad, A. (Co-Investigator), Behdad, A. (Co-Investigator), Griffith, J. W. (Other) & Griffith, J. W. (Other)
V Foundation for Cancer Research
8/1/22 → 8/1/25
Project: Research project
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Barrier Damage and The Immune Cascade: Northwestern University CounterACT Center of Excellence (NUCCX) *Admin Core A*
Lu, K. (PD/PI), Lu, K. (PD/PI), Lavker, R. M. (Co-PD/PI), Lavker, R. M. (Co-PD/PI), Guitart, J. (Co-Investigator), Guitart, J. (Co-Investigator), Kennedy, M. (Co-Investigator), Kennedy, M. (Co-Investigator), Kim, K.-Y. A. (Co-Investigator), Kim, K.-Y. A. (Co-Investigator), Paller, A. (Co-Investigator), Paller, A. (Co-Investigator), Peng, H. (Co-Investigator), Peng, H. (Co-Investigator), Perez White, B. E. (Co-Investigator), Perez White, B. E. (Co-Investigator), Dravid, V. P. (Other), Dravid, V. P. (Other), Gianneschi, N. (Other), Gianneschi, N. (Other), Goldberg, B. B. (Other), Goldberg, B. B. (Other), Le Poole, I. C. (Other), Le Poole, I. C. (Other), Miller, S. D. (Other), Miller, S. D. (Other), Nguyen, S. (Other), Nguyen, S. (Other), Rangel, S. M. (Other), Rangel, S. M. (Other), Thaxton, C. S. (Other), Thaxton, C. S. (Other), Xu, D. (Other) & Xu, D. (Other)
National Institute of Arthritis and Musculoskeletal and Skin Diseases
9/17/21 → 7/31/25
Project: Research project
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Northwestern University Clinical and Translational Science Institute
D'Aquila, R. T. (PD/PI), D'Aquila, R. T. (PD/PI), D'Aquila, R. T. (PD/PI), Lloyd-Jones, D. M. (PD/PI), Brown, C. H. (Co-PD/PI), Brown, C. H. (Co-PD/PI), Brown, C. H. (Co-PD/PI), Butt, Z. (Co-PD/PI), Butt, Z. (Co-PD/PI), Butt, Z. (Co-PD/PI), Cameron, K. A. (Co-PD/PI), Cameron, K. A. (Co-PD/PI), Cameron, K. A. (Co-PD/PI), Carnethon, M. R. (Co-PD/PI), Carnethon, M. R. (Co-PD/PI), Carnethon, M. R. (Co-PD/PI), Ciolino, J. D. (Co-PD/PI), Ciolino, J. D. (Co-PD/PI), Ciolino, J. D. (Co-PD/PI), Fleming, M. F. (Co-PD/PI), Fleming, M. F. (Co-PD/PI), Fleming, M. F. (Co-PD/PI), Hockberger, P. (Co-PD/PI), Hockberger, P. (Co-PD/PI), Hockberger, P. (Co-PD/PI), Holmes, K. (Co-PD/PI), Holmes, K. (Co-PD/PI), Holmes, K. (Co-PD/PI), Huang, W. (Co-PD/PI), Huang, W. (Co-PD/PI), Huang, W. (Co-PD/PI), Kalhan, R. (Co-PD/PI), Kalhan, R. (Co-PD/PI), Kalhan, R. (Co-PD/PI), Kandula, N. R. (Co-PD/PI), Kandula, N. R. (Co-PD/PI), Kandula, N. R. (Co-PD/PI), Luo, Y. (Co-PD/PI), Luo, Y. (Co-PD/PI), Luo, Y. (Co-PD/PI), Opal, P. (Co-PD/PI), Opal, P. (Co-PD/PI), Opal, P. (Co-PD/PI), Pfammatter, A. F. (Co-PD/PI), Pfammatter, A. F. (Co-PD/PI), Pfammatter, A. F. (Co-PD/PI), Pope, R. M. (Co-PD/PI), Pope, R. M. (Co-PD/PI), Pope, R. M. (Co-PD/PI), Ramsey-Goldman, R. (Co-PD/PI), Ramsey-Goldman, R. (Co-PD/PI), Ramsey-Goldman, R. (Co-PD/PI), Rasmussen-Torvik, L. J. (Co-PD/PI), Rasmussen-Torvik, L. J. (Co-PD/PI), Rasmussen-Torvik, L. J. (Co-PD/PI), Rosenberg, S. R. (Co-PD/PI), Rosenberg, S. R. (Co-PD/PI), Rosenberg, S. R. (Co-PD/PI), Sharma, L. (Co-PD/PI), Sharma, L. (Co-PD/PI), Sharma, L. (Co-PD/PI), Siddique, J. (Co-PD/PI), Siddique, J. (Co-PD/PI), Siddique, J. (Co-PD/PI), Smith, J. D. (Co-PD/PI), Smith, J. D. (Co-PD/PI), Smith, J. D. (Co-PD/PI), Soulakis, N. D. (Co-PD/PI), Soulakis, N. D. (Co-PD/PI), Soulakis, N. D. (Co-PD/PI), Spring, B. (Co-PD/PI), Spring, B. (Co-PD/PI), Spring, B. (Co-PD/PI), Starren, J. (Co-PD/PI), Starren, J. (Co-PD/PI), Starren, J. (Co-PD/PI), Tandon, D. (Co-PD/PI), Tandon, D. (Co-PD/PI), Tandon, D. (Co-PD/PI), Thaxton, C. S. (Co-PD/PI), Thaxton, C. S. (Co-PD/PI), Thaxton, C. S. (Co-PD/PI), Wehbe, F. (Co-PD/PI), Wehbe, F. (Co-PD/PI), Wehbe, F. (Co-PD/PI), Welty, L. J. (Co-PD/PI), Welty, L. J. (Co-PD/PI), Welty, L. J. (Co-PD/PI), Woitowich, N. C. (Co-PD/PI), Gutzman, K. E. (Other), Gutzman, K. E. (Other) & Gutzman, K. E. (Other)
National Center for Advancing Translational Sciences
7/15/19 → 6/30/25
Project: Research project
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Targeting Cholesterol Metabolism in Platinum-Resistant Ovarian Cancer
Matei, D. E. (PD/PI), Matei, D. E. (PD/PI), Matei, D. E. (PD/PI), Thaxton, C. S. (Co-PD/PI), Thaxton, C. S. (Co-PD/PI) & Thaxton, C. S. (Co-PD/PI)
U.S. Army Medical Research and Materiel Command
6/1/21 → 5/31/25
Project: Research project
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A novel therapy to ameliorate nitrogen mustard-induced limbal stem cell deficiency using lipoprotein-like nanoparticles
Kayaalp Nalbant, E., Feliciano, T. J., Mohammadlou, A., Xiong, V. L., Trujillo, J. E., Calvert, A. E., Kaplan, N., Foroozandeh, P., Kim, J., Bai, E. M., Qi, X., Tobias, F., Roth, E. W., Dravid, V. P., Lu, K., Nguyen, S. B. T., Shad Thaxton, C., Peng, H. & Lavker, R. M., Dec 2025, In: npj Regenerative Medicine. 10, 1, 14.Research output: Contribution to journal › Article › peer-review
Open Access -
Encapsulation and Delivery of the Kinase Inhibitor PIK-75 by Organic Core High-Density Lipoprotein-Like Nanoparticles Targeting Scavenger Receptor Class B Type 1
Rink, J. S., Lin, A. Y., Calvert, A. E., Kwon, D., Moxley, A., Henrich, S. E., Mohammadlou, A., Zhang, X. H., Wu, X., Querfeld, C., Griend, D. J. V., Yin, H. H., Horne, D. A., Nguyen, S. B. T., Rosen, S. T., Gordon, L. I. & Thaxton, C. S., Jan 8 2025, In: ACS Applied Materials and Interfaces. 17, 1, p. 363-373 11 p.Research output: Contribution to journal › Article › peer-review
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Keratinocyte SR-B1 expression and targeting in cytokine-driven skin inflammation
Trujillo, J., Calvert, A. E., Rink, J. S., Perez White, B. E., Sepulveda, F., Biyashev, D., Lu, K. Q., Lavker, R. M., Peng, H. & Thaxton, C. S., Dec 2025, In: Communications Medicine. 5, 1, 100.Research output: Contribution to journal › Article › peer-review
Open Access -
Nanoparticle Targeting in Chemo-Resistant Ovarian Cancer Reveals Dual Axis of Therapeutic Vulnerability Involving Cholesterol Uptake and Cell Redox Balance
Wang, Y., Calvert, A. E., Cardenas, H., Rink, J. S., Nahotko, D., Qiang, W., Ndukwe, C. E., Chen, F., Keathley, R., Zhang, Y., Cheng, J. X., Thaxton, C. S. & Matei, D., Apr 3 2024, In: Advanced Science. 11, 13, 2305212.Research output: Contribution to journal › Article › peer-review
Open Access10 Scopus citations -
Highly sensitive and ultra-rapid antigen-based detection of SARS-CoV-2 using nanomechanical sensor platform
Agarwal, D. K., Nandwana, V., Henrich, S. E., Josyula, V. P. V. N., Thaxton, C. S., Qi, C., Simons, L. M., Hultquist, J. F., Ozer, E. A., Shekhawat, G. S. & Dravid, V. P., Jan 1 2022, In: Biosensors and Bioelectronics. 195, 113647.Research output: Contribution to journal › Article › peer-review
Open Access47 Scopus citations