• 7374 Citations
20032023
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Personal profile

Research Interests

Nanotechnology is the study of the fabrication, directed self-assembly, and characterization of materials that have size dimensions between 1 and 100 nanometers. In the context of biological nanostructures, this is the size regime of the molecular machinery that constitutes, for example, functional viruses, bacteria, and human cells. The challenge of bio-nanotechnology and the focus of our lab is to control the synthesis of structures that naturally interface with biological systems to develop exquisitely targeted, practical, safe, and effective nanoparticle therapeutics, imaging agents, and biosensors.

Education/Academic qualification

PhD, Northwestern University Feinberg School of Medicine

… → 2007

MD, Northwestern University Feinberg School of Medicine

… → 2004

Research interests

  • Atherosclerosis
  • Bioengineering
  • Cancer Biology
  • Nanotechnology
  • Radiology

Fingerprint Dive into the research topics where Colby S Thaxton is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 21 Similar Profiles
Nanoparticles Medicine & Life Sciences
HDL Lipoproteins Medicine & Life Sciences
Lipoproteins Engineering & Materials Science
Gold Chemical Compounds
Prostatic Neoplasms Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Cholesterol Medicine & Life Sciences
Prostate-Specific Antigen Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Grants 2006 2023

MicroRNAs
Homeostasis
Corneal Epithelium
HDL Lipoproteins
Nanoparticles
HDL Lipoproteins
Vascular Diseases
Cholesterol
Atherosclerotic Plaques
Inflammation
Prostatic Neoplasms
Morbidity

Research Output 2003 2019

An update on synthetic high-density lipoprotein-like nanoparticles for cancer therapy

Henrich, S. E. & Thaxton, C. S., Jun 1 2019, In : Expert review of anticancer therapy. 19, 6, p. 515-528 14 p.

Research output: Contribution to journalArticle

HDL Lipoproteins
Nanoparticles
Neoplasms
Therapeutics
Biological Phenomena

Supramolecular Assembly of High-Density Lipoprotein Mimetic Nanoparticles Using Lipid-Conjugated Core Scaffolds

Henrich, S. E., Hong, B. J., Rink, J. S., Nguyen, S. & Thaxton, C. S., Jun 26 2019, In : Journal of the American Chemical Society. 141, 25, p. 9753-9757 5 p.

Research output: Contribution to journalArticle

Lipoproteins
HDL Lipoproteins
Scaffolds (biology)
Scaffolds
Nanoparticles
6 Citations (Scopus)

A Targeted, Differential Top-Down Proteomic Methodology for Comparison of ApoA-I Proteoforms in Individuals with High and Low HDL Efflux Capacity

Seckler, H. D. S., Fornelli, L., Mutharasan, R. K., Thaxton, C. S., Fellers, R., Daviglus, M., Sniderman, A., Rader, D., Kelleher, N. L., Lloyd-Jones, D. M., Compton, P. D. & Wilkins, J. T., Jun 1 2018, In : Journal of Proteome Research. 17, 6, p. 2156-2164 9 p.

Research output: Contribution to journalArticle

Apolipoprotein A-I
Proteomics
HDL Cholesterol
Bearings (structural)
Lipoylation
5 Citations (Scopus)

HDL nanoparticles targeting sonic hedgehog subtype medulloblastoma

Bell, J. B., Rink, J. S., Eckerdt, F., Clymer, J., Goldman, S., Thaxton, C. S. & Platanias, L. C., Dec 1 2018, In : Scientific reports. 8, 1, 1211.

Research output: Contribution to journalArticle

Medulloblastoma
Nanoparticles
HDL Lipoproteins
Scavenger Receptors
Ewing's Sarcoma
8 Citations (Scopus)

Nitric Oxide-Delivering High-Density Lipoprotein-like Nanoparticles as a Biomimetic Nanotherapy for Vascular Diseases

Rink, J. S., Sun, W., Misener, S., Wang, J. J., Zhang, Z. J., Kibbe, M. R., Dravid, V. P., Venkatraman, S. & Thaxton, C. S., Feb 28 2018, In : ACS Applied Materials and Interfaces. 10, 8, p. 6904-6916 13 p.

Research output: Contribution to journalArticle

Lipoproteins
Nitric oxide
Biomimetics
HDL Lipoproteins
Nitric Oxide