Grants per year
Personal profile
Research Interests
Nanotechnology is the study of the fabrication, directed self-assembly, and characterization of materials that have size dimensions between 1 and 100 nanometers. In the context of biological nanostructures, this is the size regime of the molecular machinery that constitutes, for example, functional viruses, bacteria, and human cells. The challenge of bio-nanotechnology and the focus of our lab is to control the synthesis of structures that naturally interface with biological systems to develop exquisitely targeted, practical, safe, and effective nanoparticle therapeutics, imaging agents, and biosensors.
Education/Academic qualification
PhD, Northwestern University Feinberg School of Medicine
… → 2007
MD, Northwestern University Feinberg School of Medicine
… → 2004
Research interests
- Atherosclerosis
- Bioengineering
- Cancer Biology
- Nanotechnology
- Radiology
Fingerprint Dive into the research topics where Colby S Thaxton is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
- 21 Similar Profiles
Nanoparticles
Medicine & Life Sciences
HDL Lipoproteins
Medicine & Life Sciences
Lipoproteins
Engineering & Materials Science
Gold
Chemical Compounds
Prostatic Neoplasms
Medicine & Life Sciences
Neoplasms
Medicine & Life Sciences
Cholesterol
Medicine & Life Sciences
Prostate-Specific Antigen
Medicine & Life Sciences
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Grants 2006 2023
The Role of MicroRNAs in Corneal Epithelial Homeostasis
Batlle, D., Lavker, R. M., Peng, H. & Thaxton, C. S.
Kennedy Institute - National Eye Clinic
9/1/19 → 7/31/23
Project: Research project
MicroRNAs
Homeostasis
Corneal Epithelium
HDL Lipoproteins
Nanoparticles
Highly Functional Organic Core Templated High-Density Lipoproteins to Reverse Vascular Disease
Dementieva, I. S., Thaxton, C. S. & Nguyen, S.
4/1/19 → 12/31/20
Project: Research project
HDL Lipoproteins
Vascular Diseases
Cholesterol
Atherosclerotic Plaques
Inflammation
Prostatic Neoplasms
Morbidity
Lipoteichoic acid mediated immune modulation of chronic pain
Murphy, S. F., Schaeffer, A. J., Thaxton, C. S. & Thumbikat, P.
National Institute of Diabetes, Digestive and Kidney Diseases
8/1/16 → 7/31/20
Project: Research project
Pelvic Pain
Chronic Pain
Prostatitis
Prostate
Cell Degranulation
Thaxton - Synthetic, Bioprogrammable Lipid and Lipoprotein Particles for Phospolid and Cholesterol Metabolism
Schatz, G. C., Thaxton, C. S. & Thaxton, C. S.
6/8/15 → 6/7/20
Project: Research project
Metabolism
Lipoproteins
Cholesterol
Research laboratories
Lipids
Research Output 2003 2019
An update on synthetic high-density lipoprotein-like nanoparticles for cancer therapy
Henrich, S. E. & Thaxton, C. S., Jun 1 2019, In : Expert review of anticancer therapy. 19, 6, p. 515-528 14 p.Research output: Contribution to journal › Article
HDL Lipoproteins
Nanoparticles
Neoplasms
Therapeutics
Biological Phenomena
Supramolecular Assembly of High-Density Lipoprotein Mimetic Nanoparticles Using Lipid-Conjugated Core Scaffolds
Henrich, S. E., Hong, B. J., Rink, J. S., Nguyen, S. & Thaxton, C. S., Jun 26 2019, In : Journal of the American Chemical Society. 141, 25, p. 9753-9757 5 p.Research output: Contribution to journal › Article
Lipoproteins
HDL Lipoproteins
Scaffolds (biology)
Scaffolds
Nanoparticles
6
Citations
(Scopus)
A Targeted, Differential Top-Down Proteomic Methodology for Comparison of ApoA-I Proteoforms in Individuals with High and Low HDL Efflux Capacity
Seckler, H. D. S., Fornelli, L., Mutharasan, R. K., Thaxton, C. S., Fellers, R., Daviglus, M., Sniderman, A., Rader, D., Kelleher, N. L., Lloyd-Jones, D. M., Compton, P. D. & Wilkins, J. T., Jun 1 2018, In : Journal of Proteome Research. 17, 6, p. 2156-2164 9 p.Research output: Contribution to journal › Article
Apolipoprotein A-I
Proteomics
HDL Cholesterol
Bearings (structural)
Lipoylation
5
Citations
(Scopus)
HDL nanoparticles targeting sonic hedgehog subtype medulloblastoma
Bell, J. B., Rink, J. S., Eckerdt, F., Clymer, J., Goldman, S., Thaxton, C. S. & Platanias, L. C., Dec 1 2018, In : Scientific reports. 8, 1, 1211.Research output: Contribution to journal › Article
Medulloblastoma
Nanoparticles
HDL Lipoproteins
Scavenger Receptors
Ewing's Sarcoma
8
Citations
(Scopus)
Nitric Oxide-Delivering High-Density Lipoprotein-like Nanoparticles as a Biomimetic Nanotherapy for Vascular Diseases
Rink, J. S., Sun, W., Misener, S., Wang, J. J., Zhang, Z. J., Kibbe, M. R., Dravid, V. P., Venkatraman, S. & Thaxton, C. S., Feb 28 2018, In : ACS Applied Materials and Interfaces. 10, 8, p. 6904-6916 13 p.Research output: Contribution to journal › Article
Lipoproteins
Nitric oxide
Biomimetics
HDL Lipoproteins
Nitric Oxide