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Colby S Thaxton

  • 7679 Citations
20032023

Research output per year

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Personal profile

Research Interests

Nanotechnology is the study of the fabrication, directed self-assembly, and characterization of materials that have size dimensions between 1 and 100 nanometers. In the context of biological nanostructures, this is the size regime of the molecular machinery that constitutes, for example, functional viruses, bacteria, and human cells. The challenge of bio-nanotechnology and the focus of our lab is to control the synthesis of structures that naturally interface with biological systems to develop exquisitely targeted, practical, safe, and effective nanoparticle therapeutics, imaging agents, and biosensors.

Education/Academic qualification

PhD, Northwestern University Feinberg School of Medicine

… → 2007

MD, Northwestern University Feinberg School of Medicine

… → 2004

Research interests

  • Atherosclerosis
  • Bioengineering
  • Cancer Biology
  • Nanotechnology
  • Radiology

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Grants

The role of A-to-I RNA editing in advanced prostate cancer

Thaxton, C. S. & Cao, Q.

U.S. Army Medical Research and Materiel Command

9/30/19 → 9/29/22

Project: Research project

    • The Role of MicroRNAs in Corneal Epithelial Homeostasis

    Batlle, D., Lavker, R. M., Peng, H. & Thaxton, C. S.

    Kennedy Institute - National Eye Clinic

    7/1/19 → 7/31/23

    Project: Research project

    • Highly Functional Organic Core Templated High-Density Lipoproteins to Reverse Vascular Disease

    Dementieva, I. S., Thaxton, C. S. & Nguyen, S.

    National Institute on Aging

    4/1/19 → 12/31/20

    Project: Research project

    • Lipoteichoic acid mediated immune modulation of chronic pain

    Murphy, S. F., Schaeffer, A. J., Thaxton, C. S. & Thumbikat, P.

    National Institute of Diabetes, Digestive and Kidney Diseases

    8/1/16 → 7/31/20

    Project: Research project

    • Thaxton - Synthetic, Bioprogrammable Lipid and Lipoprotein Particles for Phospolid and Cholesterol Metabolism

    Schatz, G. C., Thaxton, C. S. & Thaxton, C. S.

    Air Force Research Laboratory

    6/8/15 → 6/7/20

    Project: Research project

    • Research Output

    An update on synthetic high-density lipoprotein-like nanoparticles for cancer therapy

    Henrich, S. E. & Thaxton, C. S., Jun 3 2019, In : Expert review of anticancer therapy. 19, 6, p. 515-528 14 p.

    Research output: Contribution to journal › Review article

    • Biomimetic Magnetic Nanostructures: A Theranostic Platform Targeting Lipid Metabolism and Immune Response in Lymphoma

    Singh, A., Nandwana, V., Rink, J. S., Ryoo, S. R., Chen, T. H., Allen, S. D., Scott, E. A., Gordon, L. I., Thaxton, C. S. & Dravid, V. P., Sep 24 2019, In : ACS nano. 13, 9, p. 10301-10311 11 p.

    Research output: Contribution to journal › Article

    • 1 Scopus citations

    Supramolecular Assembly of High-Density Lipoprotein Mimetic Nanoparticles Using Lipid-Conjugated Core Scaffolds

    Henrich, S. E., Hong, B. J., Rink, J. S., Nguyen, S. B. T. & Thaxton, C. S., Jun 26 2019, In : Journal of the American Chemical Society. 141, 25, p. 9753-9757 5 p.

    Research output: Contribution to journal › Article

    • 2 Scopus citations

    A Targeted, Differential Top-Down Proteomic Methodology for Comparison of ApoA-I Proteoforms in Individuals with High and Low HDL Efflux Capacity

    Seckler, H. D. S., Fornelli, L., Mutharasan, R. K., Thaxton, C. S., Fellers, R., Daviglus, M., Sniderman, A., Rader, D., Kelleher, N. L., Lloyd-Jones, D. M., Compton, P. D. & Wilkins, J. T., Jun 1 2018, In : Journal of Proteome Research. 17, 6, p. 2156-2164 9 p.

    Research output: Contribution to journal › Article

    • 12 Scopus citations

    HDL nanoparticles targeting sonic hedgehog subtype medulloblastoma

    Bell, J. B., Rink, J. S., Eckerdt, F., Clymer, J., Goldman, S., Thaxton, C. S. & Platanias, L. C., Dec 1 2018, In : Scientific reports. 8, 1, 1211.

    Research output: Contribution to journal › Article

    • 10 Scopus citations