• 481 Citations

Research output per year

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Personal profile

Research Interests

The goal of regenerative rehabilitation is to boost innate repair processes and/or to replace tissues in order to improve function. This is the focus of my career as a physiatrist-scientist with expertise in neuromuscular medicine, rehabilitation, gene therapy, and disease modeling with induced pluripotent stem cells (iPSCs). In the clinic, I see patients with nerve injuries, neuromuscular disease, as well as perform electromyography testing. In the laboratory, I use a combination of molecular, biochemical, and electrophysiological assays to study neurotrauma, axon regeneration and motor neuron disease with a priority on human pre-clinical models involving neurons generated from patient-specific iPSCs.

1. Axon regeneration 2. Peripheral nerve diseases 3. Motor neuron disease 4. Neurotrauma 5. Nerve repair biomarkers

1. Diagnostic electrophysiology including electromyography and nerve conduction studies 2. Peripheral nerve injuries, nerve repair and nerve transfers 3. Amyotrophic lateral sclerosis/motor neuron diseases 4. Peripheral neuropathy 5. Neuromuscular ultrasound

Certifications and Licenses

Physical Medicine & Rehabilitation
Neuromuscular Medicine

Training Experience

2007Postdoctoral Fellowship, Emory University
2012Postdoctoral Fellowship, University of Calgary Faculty of Medicine, Canada
2013Internship, Northwestern University, McGaw Medical Center (Northwestern Memorial Hospital)
2017Residency, Northwestern University, McGaw Medical Center (Rehabilitation Institute of Chicago)
2018Fellowship, Northwestern University, McGaw Medical Center

Education/Academic qualification

MD, University of Calgary Faculty of Medicine

… → 2012

PhD, Dalhousie University

… → 2007

Research interests

  • ALS
  • Clinical Research
  • EMG
  • Neuromuscular Disorders
  • Peripheral Neuropathy
  • Regenerative Medicine
  • Rehabilitation/Therapy
  • Stem Cells

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Research Output

  • 481 Citations
  • 15 Article
  • 3 Review article
  • 1 Comment/debate

ALS: Management Problems

Brent, J. R., Franz, C. K., Coleman, J. M. & Ajroud-Driss, S., Aug 2020, In : Neurologic clinics. 38, 3, p. 565-575 11 p.

Research output: Contribution to journalReview article

  • Influence of limb position on assessment of nerve mechanical properties by using shear wave ultrasound elastography

    Rugel, C. L., Franz, C. K. & Lee, S. S. M., May 1 2020, In : Muscle and Nerve. 61, 5, p. 616-622 7 p.

    Research output: Contribution to journalArticle

  • Impact of traumatic brain injury on amyotrophic lateral sclerosis: From bedside to bench

    Franz, C. K., Joshi, D., Daley, E. L., Grant, R. A., Dalamagkas, K., Leung, A., Finan, J. D. & Kiskinis, E., Jan 1 2019, In : Journal of neurophysiology. 122, 3, p. 1174-1185 12 p.

    Research output: Contribution to journalReview article

  • 2 Scopus citations

    Botulinum Toxin Conditioning Enhances Motor Axon Regeneration in Mouse and Human Preclinical Models

    Franz, C. K., Puritz, A., Jordan, L. A., Chow, J., Ortega, J. A., Kiskinis, E. & Heckman, C. J., Aug 1 2018, In : Neurorehabilitation and Neural Repair. 32, 8, p. 735-745 11 p.

    Research output: Contribution to journalArticle

  • 1 Scopus citations

    Soft tissue sarcoma affecting the right shoulder of a man with paraplegia from a remote traumatic spinal cord injury: a case report

    Franz, C. K., Dalamagkas, K., Jordan, L. A. & Ephraim, G. R., Jun 26 2018, In : Spinal cord series and cases. 4, 55.

    Research output: Contribution to journalArticle

    Open Access