Grants per year
Personal profile
Research Interests
The goal of regenerative rehabilitation is to boost innate repair processes and/or to replace tissues in order to improve function. This is the focus of my career as a physiatrist-scientist with expertise in neuromuscular medicine, rehabilitation, gene therapy, and disease modeling with induced pluripotent stem cells (iPSCs). In the clinic, I see patients with nerve injuries, neuromuscular disease, as well as perform electromyography testing. In the laboratory, I use a combination of molecular, biochemical, and electrophysiological assays to study neurotrauma, axon regeneration and motor neuron disease with a priority on human pre-clinical models involving neurons generated from patient-specific iPSCs.
1. Axon regeneration 2. Peripheral nerve diseases 3. Motor neuron disease 4. Neurotrauma 5. Nerve repair biomarkers
1. Diagnostic electrophysiology including electromyography and nerve conduction studies 2. Peripheral nerve injuries, nerve repair and nerve transfers 3. Amyotrophic lateral sclerosis/motor neuron diseases 4. Peripheral neuropathy 5. Neuromuscular ultrasound
Certifications and Licenses
Physical Medicine & Rehabilitation | |
Neuromuscular Medicine |
Training Experience
2007 | Postdoctoral Fellowship, Emory University |
2012 | Postdoctoral Fellowship, University of Calgary Faculty of Medicine, Canada |
2013 | Internship, Northwestern University, McGaw Medical Center (Northwestern Memorial Hospital) |
2017 | Residency, Northwestern University, McGaw Medical Center (Rehabilitation Institute of Chicago) |
2018 | Fellowship, Northwestern University, McGaw Medical Center |
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
MD, University of Calgary Faculty of Medicine
… → 2012
PhD, Dalhousie University
… → 2007
Research interests
- ALS
- Clinical Research
- EMG
- Neuromuscular Disorders
- Peripheral Neuropathy
- Regenerative Medicine
- Rehabilitation/Therapy
- Stem Cells
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Network
Grants
- 2 Finished
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Exercise in a Dish: Studying the Effects of Activity Based Treatments for Neuromuscular Disorders with Human Induced Pluripotent Stem Cells and Optogenetics
Franz, C. K., Heckman, C. & Kiskinis, E.
Rehabilitation Institute of Chicago, Craig H. Neilsen Foundation
6/1/16 → 3/31/18
Project: Research project
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Diaphragm and Phrenic Nerve Ultrasound in COVID-19 Patients and Beyond: Imaging Technique, Findings, and Clinical Applications
Patel, Z., Franz, C. K., Bharat, A., Walter, J. M., Wolfe, L. F., Koralnik, I. J. & Deshmukh, S., Feb 2022, In: Journal of Ultrasound in Medicine. 41, 2, p. 285-299 15 p.Research output: Contribution to journal › Review article › peer-review
1 Scopus citations -
Advanced Materials in Wireless, Implantable Electrical Stimulators that Offer Rapid Rates of Bioresorption for Peripheral Axon Regeneration
Guo, H., D'Andrea, D., Zhao, J., Xu, Y., Qiao, Z., Janes, L. E., Murthy, N. K., Li, R., Xie, Z., Song, Z., Meda, R., Koo, J., Bai, W., Choi, Y. S., Jordan, S. W., Huang, Y., Franz, C. K. & Rogers, J. A., Jul 16 2021, In: Advanced Functional Materials. 31, 29, 2102724.Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
Author Correction: Stretchable, dynamic covalent polymers for soft, long-lived bioresorbable electronic stimulators designed to facilitate neuromuscular regeneration (Nature Communications, (2020), 11, 1, (5990), 10.1038/s41467-020-19660-6)
Choi, Y. S., Hsueh, Y. Y., Koo, J., Yang, Q., Avila, R., Hu, B., Xie, Z., Lee, G., Ning, Z., Liu, C., Xu, Y., Lee, Y. J., Zhao, W., Fang, J., Deng, Y., Lee, S. M., Vázquez-Guardado, A., Stepien, I., Yan, Y., Song, J. W. & 13 others, , Dec 2021, In: Nature communications. 12, 1, 415.Research output: Contribution to journal › Comment/debate › peer-review
Open Access1 Scopus citations -
Biofidelic dynamic compression of human cortical spheroids reproduces neurotrauma phenotypes
Shoemaker, A. R., Jones, I. E., Jeffris, K. D., Gabrielli, G., Togliatti, A. G., Pichika, R., Martin, E., Kiskinis, E., Franz, C. K. & Finan, J. D., Dec 2021, In: DMM Disease Models and Mechanisms. 14, 12, dmm048916.Research output: Contribution to journal › Article › peer-review
Open Access -
Diaphragm dysfunction in severe COVID-19 as determined by neuromuscular ultrasound
Farr, E., Wolfe, A. R., Deshmukh, S., Rydberg, L., Soriano, R., Walter, J. M., Boon, A. J., Wolfe, L. F. & Franz, C. K., Aug 2021, In: Annals of clinical and translational neurology. 8, 8, p. 1745-1749 5 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations