Colin Thomas Gillespie

  • 531 Citations
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Personal profile

Research Interests

Dr. Gillespie's clinical interest includes the treatment of thoracic malignancies, specifically with regard to the application of novel technologies in Interventional Pulmonology to improve the diagnosis and treat thoracic malignancies with minimal invasiveness. He also has extensive experience in the bronchoscopic management of tracheal stenosis and the airway complications associated with Lung Transplantation. Dr Gillespie has advanced training in the following techniques: flexible and rigid bronchoscopy, balloon bronchoplasty, endobronchial stent placement (silicon, hybrid, and metallic), electrosurgery (including argon plasma coagulation, lasers, and cautery tools), endobronchial brachytherapy, photodynamic therapy, endobronchial ultrasound (both convex and radial imaging), navigational bronchoscopy, auto-fluorescence bronchoscopy (LIFE), multiple biopsy tools, percutaneous tracheotomy, and pleuroscopy. His academic focus is on clinical research and education. He was the principle investigator on a Phase III study looking at the placement of bilateral Intrabronchial Valves for the treatment of patients with heterogeneous emphysema. Dr. Gillespie has also been involved in projects aimed to utilize advanced bronchoscopic techniques to improve diagnostic yield of lung nodules and masses, treat diseases such as tracheomalacia and severe asthma, as well as banking tissue samples for basic research. As an educator, he has a keen interest in simulation based learning. He has been working to develop simulations designed to accelerate the acquisition of advanced bronchoscopic and procedural skills.

Certifications and Licenses

Critical Care Medicine
Pulmonary Disease
Internal Medicine

Training Experience

2001Internship, University of Pennsylvania Hospitals
2003Residency, University of Pennsylvania Hospitals
2006Fellowship, University of Pennsylvania Hospitals

Education/Academic qualification

MD, Chicago Medical School

… → 2000


  • Airway Obstruction
  • Aspirated Foreign Bodies
  • Interventional Pulmonology
  • Lung Cancer / Chest Cancer
  • Lungs / Breathing Problems
  • Mediastinal Adenopathy
  • Pleural Effusion
  • Tracheal Stenosis

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Grants 2016 2021

Research Output 2006 2018

  • 531 Citations
  • 29 Article
  • 2 Review article
  • 1 Comment/debate
  • 1 Editorial

A young man with fevers and an invasive mediastinal mass

Sala, M. A., Celli, D., Yeldandi, A. V., Gillespie, C. T. & Argento, A. C., Dec 1 2018, In : Annals of the American Thoracic Society. 15, 12, p. 1477-1482 6 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Robotic Endoscopic Airway Challenge: REACH Assessment

Chen, A. C. & Gillespie, C. T., Jul 1 2018, In : Annals of Thoracic Surgery. 106, 1, p. 293-297 5 p.

Research output: Contribution to journalArticle


Single-Cell Transcriptomic Analysis of Human Lung Provides Insights into the Pathobiology of Pulmonary Fibrosis

Reyfman, P. A., Walter, J. M., Joshi, N., Anekalla, K. R., McQuattie-Pimentel, A. C., Chiu, S., Fernandez, R., Akbarpour, M., Chen, C-I., Ren, Z., Verma, R., Abdala-Valencia, H., Nam, K., Chi, M., Han, S., Gonzalez-Gonzalez, F. J., Soberanes, S., Watanabe, S., Williams, K. J. N., Flozak, A. S. & 29 othersNicholson, T. T., Morgan, V. K., Winter, D. R., Hinchcliff, M., Hrusch, C. L., Guzy, R. D., Bonham, C. A., Sperling, A. I., Bag, R., Hamanaka, R. B., Mutlu, G. M., Yeldandi, A. V., Marshall, S. A., Shilatifard, A., Amaral, L. A. N., Perlman, H., Sznajder, J. I., Argento, A. C., Gillespie, C. T., Dematte, J., Jain, M., Singer, B. D., Ridge, K. M., Lam, A. P., Bharat, A., Bhorade, S. M., Gottardi, C. J., Budinger, G. R. S. & Misharin, A. V., Dec 15 2018, In : American Journal of Respiratory and Critical Care Medicine.

Research output: Contribution to journalArticle

Single-Cell Analysis
Pulmonary Fibrosis
RNA Sequence Analysis
Alveolar Macrophages
8 Citations (Scopus)

Bronchial effects of cryoballoon ablation for atrial fibrillation

Verma, N., Gillespie, C. T., Argento, A. C., Tomson, T., Dandamudi, S., Piña, P., Ringwala, S., Lin, A. C., Chicos, A. B., Kim Koss, S. S., Arora, R. K., Passman, R. S. & Knight, B. P., Jan 1 2017, In : Heart Rhythm. 14, 1, p. 12-16 5 p.

Research output: Contribution to journalArticle

Pulmonary Veins
Atrial Fibrillation
22 Citations (Scopus)

Interventional Pulmonology Fellowship Accreditation Standards: Executive Summary of the Multisociety Interventional Pulmonology Fellowship Accreditation Committee

Mullon, J. J., Burkart, K. M., Silvestri, G., Hogarth, D. K., Almeida, F., Berkowitz, D., Eapen, G. A., Feller-Kopman, D., Fessler, H. E., Folch, E., Gillespie, C. T., Haas, A., Islam, S. U., Lamb, C., Levine, S. M., Majid, A., Maldonado, F., Musani, A. I., Piquette, C., Ray, C. & 5 othersReddy, C. B., Rickman, O., Simoff, M., Wahidi, M. M. & Lee, H., May 1 2017, In : Chest. 151, 5, p. 1114-1121 8 p.

Research output: Contribution to journalArticle

Pulmonary Medicine
Graduate Medical Education