Grants per year
Personal profile
Research Interests
Professor Craig B. Langman, is the Isaac A. Abt, MD, Professor of Kidney Diseases, and Tenured Professor of Pediatrics at the Feinberg School of Medicine, Northwestern University, Head of Kidney Diseases at the Ann and Robert H Lurie Children’s Hospital of Chicago, and director of the two Davita Children’s Dialysis Centers in Chicago. His funded research focuses on the basic and clinical expression of inherited or acquired disorders of calcium, phosphorus vitamin D, and FGF23 metabolism, mechansims of cardiovascular diseases in children with obesity or chronic kidney disease, the proteomics of inherited stone disease, inherited genetic diseases (cystinosis, oxalosis, kidney stones, atypical HUS, hypophosphatasia), and the rehabilitation of patients around the world with chronic kidney disease. Professor Langman has published more than 250 articles, reviews and chapters in his discipline.
The PI has the following major areas of hypothesis-driven research that are studied and supported: urinary proteomics in genetic kidney stone diseases; mechanisms of progression in chronic kidney diseases; rare genetic kidney diseases including atypical HUS, cystinosis, and Alport Syndrome.
Rare genetic kidney diseases Osteoporosis in children Inherited and acquired bone disease in children Disorders of calcification Disorders of phosphorus metabollsim Chronic Kidney Diseases of childhood
Certifications and Licenses
| Pediatrics | |
| Pediatric Nephrology |
Training Experience
| 1979 | Residency, Children's Hospital of Philadelphia |
| 1981 | Fellowship, Children's Hospital of Philadelphia |
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
MD, Medicine, Hahnemann University
… → 1977
Research interests keywords
- Cardiovascular Diseases
- Cytokines
- Genetics
- Inflammation
- Kidney
- Nutritional and Metabolic Diseases
- Osteoporosis
- Physiology
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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The Northwestern Summer Research Program for Medical Students
Ladner, D. P. (PD/PI), Ladner, D. P. (PD/PI), Feinstein, M. J. (Other), Feinstein, M. J. (Other) & Langman, C. (Other)
National Institute of Diabetes and Digestive and Kidney Diseases
9/1/21 → 8/31/26
Project: Research project
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North American Pediatric Renal Transplant Cooperative Study--Cystinosis Registry
Langman, C. (PD/PI)
North American Pediatrics Renal Transplant Case Study
11/14/18 → 8/31/50
Project: Research project
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Fertility Management in Cystinosis: A Clinical Perspective
Langman, C. B., Delos Santos, R. B., Ghossein, C., Atherton, A. M., Levtchenko, E. N. & Servais, A., Feb 2024, In: Kidney International Reports. 9, 2, p. 214-224 11 p.Research output: Contribution to journal › Review article › peer-review
Open Access -
Adherence to the 2017 Clinical Practice Guidelines for Pediatric Hypertension in Safety-Net Clinics
Carroll, A. J., Tedla, Y. G., Padilla, R., Jain, A., Segovia, E., Moin, A., Wallace, A. S., Sanuade, O. A., Langman, C. B., Mohanty, N. & Smith, J. D., Apr 14 2023, In: JAMA network open. 6, 4, p. E237043Research output: Contribution to journal › Article › peer-review
Open Access14 Scopus citations -
Baseline Clinical Characteristics and Complement Biomarkers of Patients with C3 Glomerulopathy Enrolled in Two Phase 2 Studies Investigating the Factor D Inhibitor Danicopan
Podos, S. D., Trachtman, H., Appel, G. B., Bomback, A. S., Dixon, B. P., Wetzels, J. F. M., Cook, H. T., Parikh, S. V., Pickering, M. C., Tumlin, J., Langman, C. B., Lightstone, L., Sperati, C. J., Daina, E., Bouman, K. P., Rice, K., Thanassi, J. A., Huang, M., Nester, C. & Remuzzi, G., Jan 1 2023, In: American Journal of Nephrology. 53, 10, p. 675-686 12 p.Research output: Contribution to journal › Article › peer-review
Open Access10 Scopus citations -
Blood Pressure Classification Status in Children With CKD Following Adoption of the 2017 American Academy of Pediatrics Guideline
CKiD Study Investigators, May 2023, In: American Journal of Kidney Diseases. 81, 5, p. 545-553 9 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Clinical Outcomes of Patients with C3G or IC-MPGN Treated with the Factor D Inhibitor Danicopan: Final Results from Two Phase 2 Studies
Nester, C., Appel, G. B., Bomback, A. S., Bouman, K. P., Cook, H. T., Daina, E., Dixon, B. P., Rice, K., Najafian, N., Hui, J., Podos, S. D., Langman, C. B., Lightstone, L., Parikh, S. V., Pickering, M. C., Sperati, C. J., Trachtman, H., Tumlin, J., De Vries, A. P. J. & Wetzels, J. F. M. & 1 others, , Jan 1 2023, In: American Journal of Nephrology. 53, 10, p. 687-700 14 p.Research output: Contribution to journal › Article › peer-review
Open Access29 Scopus citations
Datasets
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Supplementary Material for: Clinical Outcomes of Patients with C3G or IC-MPGN Treated with the Factor D Inhibitor Danicopan: Final Results from Two Phase 2 Studies
Nester, C. (Contributor), Appel, G. B. (Contributor), Bomback, A. S. (Contributor), Bouman, K. P. (Contributor), Cook, H. T. (Contributor), Daina, E. (Contributor), Dixon, B. P. (Contributor), Rice, K. (Contributor), Najafian, N. (Contributor), Hui, J. (Contributor), Langman, C. B. (Contributor), Lightstone, L. (Contributor), Parikh, S. V. (Contributor), Pickering, M. C. (Contributor), Sperati, C. J. (Contributor), Trachtman, H. (Contributor), Tumlin, J. (Contributor), Wetzels, J. F. M. (Contributor) & Remuzzi, G. (Contributor), Karger Publishers, 2022
DOI: 10.6084/m9.figshare.21617358.v1, https://karger.figshare.com/articles/dataset/Supplementary_Material_for_Clinical_Outcomes_of_Patients_with_C3G_or_IC-MPGN_Treated_with_the_Factor_D_Inhibitor_Danicopan_Final_Results_from_Two_Phase_2_Studies/21617358/1
Dataset
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Structural and non-coding variants increase the diagnostic yield of clinical whole genome sequencing for rare diseases
Maroofian, R. (Creator), Stevenson, M. M. (Creator), Javaid, K. M. (Creator), Marsden, B. D. (Creator), Kelly, D. A. (Creator), Dhalla, F. (Creator), Scott, C. R. (Creator), Dacal, B. D. (Creator), Schuh, A. H. (Creator), Mansour, S. (Creator), Bento, C. (Creator), Cilliers, D. D. (Creator), Dunford, J. E. (Creator), Riva, S. G. (Creator), Lu, X. (Creator), Langman, C. B. (Creator), Thakker, R. V. (Creator), Schilling, K. D. (Creator), Schwessinger, R. (Creator), McGowan, S. J. (Creator), Smith, C. (Creator), Kreins, A. Y. (Creator), Mason, J. (Creator), Pugh, C. W. (Creator), van Wijk, R. H. A. (Creator), Conti, V. (Creator), Mlcochova, H. (Creator), Babbs, C. (Creator), Ben-Ami, T. (Creator), Wilkie, A. O. M. (Creator), Manzur, A. Y. (Creator), Brasch-Andersen, C. (Creator), Patel, S. Y. (Creator), Hashimoto, A. (Creator), Baños-Piñero, B. (Creator), Rad, A. (Creator), Ansorge, O. (Creator), Twigg, S. R. F. (Creator), Harris, A. L. (Creator), Lester, T. (Creator), Sen, A. (Creator), Kelly, D. F. (Creator), Davies, E. G. (Creator), Holländer, G. A. (Contributor), Calpena, E. (Creator), Bull, K. R. (Creator), Palace, J. (Creator), Ramesh, A. (Creator), Murakami, Y. (Creator), Cario, H. (Creator), Wall, S. A. (Creator), Allroggen, H. (Creator), Guerrini, R. (Creator), Mei, D. (Creator), Okoli, S. (Creator), Lord, S. R. (Creator), Hartley, J. L. (Creator), Roy, N. B. A. (Creator), Kane, M. A. (Creator), Wang, J. (Creator), Bennett, D. L. H. (Creator), Ousager, L. B. (Creator) & Hughes, J. R. (Creator), figshare, 2024
DOI: 10.6084/m9.figshare.c.6923686.v1, https://springernature.figshare.com/collections/Structural_and_non-coding_variants_increase_the_diagnostic_yield_of_clinical_whole_genome_sequencing_for_rare_diseases/6923686/1
Dataset
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PowerPoint Slides for: A Double-Blind, Placebo Controlled, Randomized Phase 1 Cross-Over Study with ALLN-177, an Orally Administered Oxalate Degrading Enzyme
Langman, C. B. (Creator), Grujic, D. (Creator), Pease, R. M. (Creator), Easter, L. (Creator), Nezzer, J. (Creator), Margolin, A. (Creator) & Brettman, L. (Creator), Karger Publishers, 2016
DOI: 10.6084/m9.figshare.3635727.v3, https://karger.figshare.com/articles/dataset/PowerPoint_Slides_for_A_Double-Blind_Placebo_Controlled_Randomized_Phase_1_Cross-Over_Study_with_ALLN-177_an_Orally_Administered_Oxalate_Degrading_Enzyme/3635727/3 and one more link, https://karger.figshare.com/articles/dataset/PowerPoint_Slides_for_A_Double-Blind_Placebo_Controlled_Randomized_Phase_1_Cross-Over_Study_with_ALLN-177_an_Orally_Administered_Oxalate_Degrading_Enzyme/3635727 (show fewer)
Dataset
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Additional file 1 of A stakeholder-driven method for selecting implementation strategies: a case example of pediatric hypertension clinical practice guideline implementation
Knapp, A. A. (Creator), Carroll, A. J. (Creator), Mohanty, N. (Creator), Fu, E. (Creator), Powell, B. J. (Creator), Hamilton, A. (Creator), Burton, N. D. (Creator), Coldren, E. (Creator), Hossain, T. (Creator), Limaye, D. P. (Creator), Mendoza, D. (Creator), Sethi, M. (Creator), Padilla, R. (Creator), Price, H. E. (Creator), Villamar, J. A. (Creator), Jordan, N. (Creator), Langman, C. B. (Creator) & Smith, J. D. (Creator), figshare, 2022
DOI: 10.6084/m9.figshare.19320911, https://springernature.figshare.com/articles/dataset/Additional_file_1_of_A_stakeholder-driven_method_for_selecting_implementation_strategies_a_case_example_of_pediatric_hypertension_clinical_practice_guideline_implementation/19320911
Dataset
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Optimizing the implementation of a population panel management intervention in safety-net clinics for pediatric hypertension (The OpTIMISe–Pediatric Hypertension Study)
Smith, J. D. (Creator), Mohanty, N. (Contributor), Davis, M. M. (Creator), Knapp, A. A. (Creator), Tedla, Y. G. (Creator), Carroll, A. J. (Creator), Price, H. E. (Creator), Villamar, J. A. (Creator), Padilla, R. (Creator), Jordan, N. (Creator), Brown, C. H. (Contributor) & Langman, C. B. (Creator), figshare, 2020
DOI: 10.6084/m9.figshare.c.5040209, https://springernature.figshare.com/collections/Optimizing_the_implementation_of_a_population_panel_management_intervention_in_safety-net_clinics_for_pediatric_hypertension_The_OpTIMISe_Pediatric_Hypertension_Study_/5040209
Dataset