Curt M Horvath

  • 12128 Citations
1990 …2023
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Personal profile

Education/Academic qualification

PhD, Northwestern University

… → 1992

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Interferons Medicine & Life Sciences
Antiviral Agents Medicine & Life Sciences
Proteins Medicine & Life Sciences
Respirovirus Agriculture & Biology
Transcription Chemical Compounds
Viruses Chemical Compounds
Virus Diseases Medicine & Life Sciences
Transducers Medicine & Life Sciences

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Grants 2007 2023

HTAL Shared Resource

Horvath, C. M.

National Cancer Institute

8/10/187/31/23

Project: Research project

Neoplasms
Medicine
Research
Population

Pilot Year 01

Horvath, C. M. & Mirkin, C. A.

National Cancer Institute

9/1/157/31/20

Project: Research project

Nucleic Acids
Nanostructures
Therapeutics
Neoplasms
Nanotechnology

Research Output 1990 2018

Constitutively Active MDA5 Proteins Are Inhibited by Paramyxovirus v Proteins

Mandhana, R., Qian, L. K. & Horvath, C. M., Aug 1 2018, In : Journal of Interferon and Cytokine Research. 38, 8, p. 319-332 14 p.

Research output: Contribution to journalArticle

Interferons
Proteins
Mutation
Antiviral Agents
Gene Expression
16 Citations (Scopus)

Deep sequencing of HIV-1 reverse transcripts reveals the multifaceted antiviral functions of APOBEC3G

Pollpeter, D., Parsons, M., Sobala, A. E., Coxhead, S., Lang, R. D., Bruns, A. M., Papaioannou, S., McDonnell, J. M., Apolonia, L., Chowdhury, J. A., Horvath, C. M. & Malim, M. H., Feb 1 2018, In : Nature Microbiology. 3, 2, p. 220-233 14 p.

Research output: Contribution to journalArticle

High-Throughput Nucleotide Sequencing
Antiviral Agents
HIV-1
Complementary DNA
Uridine
4 Citations (Scopus)

Histone H2A.Z Suppression of Interferon-Stimulated Transcription and Antiviral Immunity Is Modulated by GCN5 and BRD2

Au-Yeung, N. & Horvath, C. M., Aug 31 2018, In : iScience. 6, p. 68-82 15 p.

Research output: Contribution to journalArticle

Open Access
interferons
Allergy and Immunology
transcriptomics
immunology
histones
1 Citation (Scopus)

IFN--inducible antiviral responses require ULK1-mediated activation of MLK3 and ERK5

Nora Vaz Saleiro, D., Blyth, G. T., Kosciuczuk, E. M., Ozark, P. A., Majchrzak-Kita, B., Arslan, A. D., Fischietti, M., Reddy, N. K., Horvath, C. M., Davis, R. J., Fish, E. N. & Platanias, L. C., Nov 20 2018, In : Science Signaling. 11, 557, aap9921.

Research output: Contribution to journalArticle

Interferons
Antiviral Agents
Phosphotransferases
Chemical activation
Autophagy
4 Citations (Scopus)

RNA sensor LGP2 inhibits TRAF ubiquitin ligase to negatively regulate innate immune signaling

Parisien, J. P., Lenoir, J. J., Mandhana, R., Rodriguez, K. R., Qian, K., Bruns, A. M. & Horvath, C. M., Jun 1 2018, In : EMBO Reports. 19, 6, e45176.

Research output: Contribution to journalArticle

Ligases
Ubiquitin
Antiviral Agents
RNA
Sensors