Grants per year
Personal profile
Research Interests
My research is focused on the mechanisms underlying Parkinson's disease, Huntington's disease and chronic pain. This pursuit employs a combination of electrophysiological, optical, genetic and behavioral approaches.
Education/Academic qualification
PhD, University of Washington
… → 1983
MS, University of Oregon
… → 1976
Keywords
- Molecular Biology
- Movement Disorders
- Neuroscience
- Parkinson’s Disease
- Physiology
- Schizophrenia
Fingerprint Fingerprint is based on mining the text of the experts' scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.
- 36 Similar Profiles
Neurons
Medicine & Life Sciences
Corpus Striatum
Medicine & Life Sciences
Parkinson Disease
Medicine & Life Sciences
Dopaminergic Neurons
Medicine & Life Sciences
Dopamine
Medicine & Life Sciences
Cholinergic Agents
Medicine & Life Sciences
Interneurons
Medicine & Life Sciences
Calcium
Medicine & Life Sciences
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Grants 2000 2024
Dr. Surmeier Subproject for SP0049303
National Institute of General Medical Sciences
5/1/19 → 4/30/24
Project: Research project
Nitric Oxide Synthase Type I
Melanoma
Nitric Oxide Synthase
Cerebral Palsy
Hydrogen Peroxide
Selective inhibition of nitric oxide synthase for multiple indications
Silverman, R. B. & Surmeier Jr, D. J.
National Institute of General Medical Sciences
5/1/19 → 4/30/24
Project: Research project
Nitric Oxide Synthase Type I
Nitric Oxide Synthase
Melanoma
Cerebral Palsy
Hydrogen Peroxide
Molecular and Cellular Mechanisms of Parkinson’s Disease
Guzman-Lucero, J. N., Kondapalli, J., Shen, W., Surmeier Jr, D. J. & Wokosin, D. L.
11/1/18 → 10/31/21
Project: Research project
Parkinson Disease
Levodopa
Dopaminergic Neurons
Dyskinesias
Substantia Nigra
Autism-Associated Mutations in L-Type Ca2+ Channels
U.S. Army Medical Research and Materiel Command
9/30/18 → 9/29/21
Project: Research project
Autistic Disorder
Mutation
Ion Channels
Brain
Neurons
Determinants of Dopaminergic Neuron Degeneration in Parkinson's Disease
Guzman-Lucero, J. N. & Surmeier Jr, D. J.
National Institute of Neurological Disorders and Stroke
9/15/18 → 8/31/19
Project: Research project
Subthalamic Nucleus
Nerve Degeneration
Dopaminergic Neurons
Parkinson Disease
National Institute of Neurological Disorders and Stroke
Research Output 1985 2019
3
Citations
(Scopus)
Cholinergic Interneurons Amplify Thalamostriatal Excitation of Striatal Indirect Pathway Neurons in Parkinson's Disease Models
Tanimura, A., Du, Y., Kondapalli, J., Wokosin, D. L. & Surmeier Jr, D. J., Feb 6 2019, In : Neuron. 101, 3, p. 444-458.e6Research output: Contribution to journal › Article
Intralaminar Thalamic Nuclei
Corpus Striatum
Interneurons
Cholinergic Agents
Parkinson Disease
2
Citations
(Scopus)
Delayed spine pruning of direct pathway spiny projection neurons in a mouse model of parkinson’s disease
Graves, S. M. & Surmeier Jr, D. J., Jan 29 2019, In : Frontiers in Cellular Neuroscience. 13, 32.Research output: Contribution to journal › Article
Open Access
Parkinson Disease
Spine
Neurons
Oxidopamine
Synapses
1
Citation
(Scopus)
Dopaminergic modulation of striatal function and Parkinson’s disease
Zhai, S., Shen, W., Graves, S. M. & Surmeier Jr, D. J., Jan 1 2019, In : Journal of Neural Transmission.Research output: Contribution to journal › Review article
Corpus Striatum
Parkinson Disease
Dyskinesias
Levodopa
Dopamine
Enhanced striatopallidal gamma-aminobutyric acid (GABA) A receptor transmission in mouse models of huntington's disease
Perez-Rosello, T., Gelman, S., Tombaugh, G., Cachope, R., Beaumont, V. & Surmeier Jr, D. J., Jan 1 2019, In : Movement Disorders.Research output: Contribution to journal › Article
GABA Receptors
Huntington Disease
Synaptic Transmission
Neurons
gamma-Aminobutyric Acid
Mutant huntingtin enhances activation of dendritic Kv4 K + channels in striatal spiny projection neurons
Carrillo-Reid, L., Day, M., Xie, Z., Melendez, A. E., Kondapalli, J., Plotkin, J. L., Wokosin, D. L., Chen, Y., Kress, G. J., Kaplitt, M., Ilijic, E., Guzman-Lucero, J. N., Chan, S. S. & Surmeier Jr, D. J., Apr 24 2019, In : eLife. 8Research output: Contribution to journal › Article
Open Access
Corpus Striatum
Huntington Disease
Neurons
Chemical activation
trkB Receptor