• 22737 Citations
1985 …2024
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Personal profile

Research Interests

My research is focused on the mechanisms underlying Parkinson's disease, Huntington's disease and chronic pain. This pursuit employs a combination of electrophysiological, optical, genetic and behavioral approaches.

Education/Academic qualification

PhD, University of Washington

… → 1983

MS, University of Oregon

… → 1976

Keywords

  • Molecular Biology
  • Movement Disorders
  • Neuroscience
  • Parkinson’s Disease
  • Physiology
  • Schizophrenia

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Grants 2000 2024

Nitric Oxide Synthase Type I
Nitric Oxide Synthase
Melanoma
Cerebral Palsy
Hydrogen Peroxide
Parkinson Disease
Levodopa
Dopaminergic Neurons
Dyskinesias
Substantia Nigra
Autistic Disorder
Mutation
Ion Channels
Brain
Neurons
Subthalamic Nucleus
Nerve Degeneration
Dopaminergic Neurons
Parkinson Disease
National Institute of Neurological Disorders and Stroke
Chronic Pain
Opioid Analgesics
Opiate Alkaloids
Brain
Back Pain

Research Output 1985 2019

1 Citation (Scopus)

Cholinergic Interneurons Amplify Thalamostriatal Excitation of Striatal Indirect Pathway Neurons in Parkinson's Disease Models

Tanimura, A., Du, Y., Kondapalli, J., Wokosin, D. L. & Surmeier Jr, D. J., Feb 6 2019, In : Neuron. 101, 3, p. 444-458.e6

Research output: Contribution to journalArticle

Intralaminar Thalamic Nuclei
Corpus Striatum
Interneurons
Cholinergic Agents
Parkinson Disease
2 Citations (Scopus)
Open Access
Parkinson Disease
Spine
Neurons
Oxidopamine
Synapses

Dopaminergic modulation of striatal function and Parkinson’s disease

Zhai, S., Shen, W., Graves, S. M. & Surmeier Jr, D. J., Jan 1 2019, In : Journal of Neural Transmission.

Research output: Contribution to journalReview article

Corpus Striatum
Parkinson Disease
Dyskinesias
Levodopa
Dopamine

Enhanced striatopallidal gamma-aminobutyric acid (GABA) A receptor transmission in mouse models of huntington's disease

Perez-Rosello, T., Gelman, S., Tombaugh, G., Cachope, R., Beaumont, V. & Surmeier Jr, D. J., Jan 1 2019, In : Movement Disorders.

Research output: Contribution to journalArticle

GABA Receptors
Huntington Disease
Synaptic Transmission
Neurons
gamma-Aminobutyric Acid

Parkinson's disease: Is it a consequence of human brain evolution?

Diederich, N. J., Surmeier Jr, D. J., Uchihara, T., Grillner, S. & Goetz, C. G., Apr 1 2019, In : Movement Disorders. 34, 4, p. 453-459 7 p.

Research output: Contribution to journalArticle

Open Access
Parkinson Disease
Brain