• 21720 Citations
1985 …2023
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Personal profile

Research Interests

My research is focused on the mechanisms underlying Parkinson's disease and schizophrenia. This pursuit employs a combination of electrophysiological, optical, genetic and behavioral approaches.

Research Interests

My research is focused on the mechanisms underlying Parkinson's disease, Huntington's disease and chronic pain. This pursuit employs a combination of electrophysiological, optical, genetic and behavioral approaches.

Education/Academic qualification

PhD, University of Washington

… → 1983

MS, University of Oregon

… → 1976

Keywords

  • Molecular Biology
  • Movement Disorders
  • Neuroscience
  • Parkinson’s Disease
  • Physiology
  • Schizophrenia

Fingerprint Fingerprint is based on mining the text of the experts' scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

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Grants 2000 2023

Parkinson Disease
Levodopa
Dopaminergic Neurons
Dyskinesias
Substantia Nigra
Autistic Disorder
Mutation
Ion Channels
Brain
Neurons
Subthalamic Nucleus
Nerve Degeneration
Dopaminergic Neurons
Parkinson Disease
National Institute of Neurological Disorders and Stroke
Chronic Pain
Opioid Analgesics
Opiate Alkaloids
Brain
Back Pain

Research Output 1985 2018

Characterization of CNTNAP2 nanostructures on interneuronal dendrites

Gao, R., Piguel, N. H., Melendez-Zaidi, A. E., Martin-de-Saavedra, M. D., Yoon, S., Forrest, M. P., Myczek, K., Zhang, G., Russell, T. A., Csernansky, J. G., Surmeier Jr, D. J. & Penzes, P., Sep 1 2018, In : Molecular Psychiatry. 23, 9, 1 p.

Research output: Contribution to journalArticle

Nanostructures
Dendrites

CNTNAP2 stabilizes interneuron dendritic arbors through CASK

Gao, R., Piguel, N. H., Melendez-Zaidi, A. E., Martin-de-Saavedra, M. D., Yoon, S., Forrest, M. P., Myczek, K., Zhang, G., Russell, T. A., Csernansky, J. G., Surmeier Jr, D. J. & Penzes, P., Apr 2 2018, (Accepted/In press) In : Molecular Psychiatry. p. 1-19 19 p.

Research output: Contribution to journalArticle

Contactins
Calcium-Calmodulin-Dependent Protein Kinases
Protein-Serine-Threonine Kinases
Interneurons
Knockout Mice
2 Citations

Determinants of dopaminergic neuron loss in Parkinson's disease

Surmeier Jr, D. J., Jan 1 2018, (Accepted/In press) In : FEBS Journal.

Research output: Contribution to journalArticle

Dopaminergic Neurons
Neurons
Parkinson Disease
Pathology
Synucleins
4 Citations

Striatal cholinergic interneurons and Parkinson's disease

Tanimura, A., Pancani, T., Lim, S. A. O., Tubert, C., Melendez, A. E., Shen, W. & Surmeier Jr, D. J., May 1 2018, In : European Journal of Neuroscience. 47, 10, p. 1148-1158 11 p.

Research output: Contribution to journalReview article

Corpus Striatum
Interneurons
Cholinergic Agents
Parkinson Disease
Optogenetics
11 Citations

Striatal synapses, circuits, and Parkinson's disease

Zhai, S., Tanimura, A., Graves, S. M., Shen, W. & Surmeier Jr, D. J., Feb 1 2018, In : Current opinion in neurobiology. 48, p. 9-16 8 p.

Research output: Contribution to journalReview article

Corpus Striatum
Synapses
Parkinson Disease
Aptitude
Basal Ganglia