Grants per year
Personal profile
Research Interests
My research is focused on the mechanisms underlying Parkinson's disease, Huntington's disease and chronic pain. This pursuit employs a combination of electrophysiological, optical, genetic and behavioral approaches.
Education/Academic qualification
PhD, University of Washington
… → 1983
MS, University of Oregon
… → 1976
Keywords
- Molecular Biology
- Movement Disorders
- Neuroscience
- Parkinson’s Disease
- Physiology
- Schizophrenia
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Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Grants 2000 2023
Molecular and Cellular Mechanisms of Parkinson’s Disease
Guzman-Lucero, J. N., Kondapalli, J., Shen, W., Surmeier Jr, D. J. & Wokosin, D. L.
11/1/18 → 10/31/21
Project: Research project
Parkinson Disease
Levodopa
Dopaminergic Neurons
Dyskinesias
Substantia Nigra
Autism-Associated Mutations in L-Type Ca2+ Channels
U.S. Army Medical Research and Materiel Command
9/30/18 → 9/29/21
Project: Research project
Autistic Disorder
Mutation
Ion Channels
Brain
Neurons
Determinants of Dopaminergic Neuron Degeneration in Parkinson's Disease
Guzman-Lucero, J. N. & Surmeier Jr, D. J.
National Institute of Neurological Disorders and Stroke
9/15/18 → 8/31/19
Project: Research project
Subthalamic Nucleus
Nerve Degeneration
Dopaminergic Neurons
Parkinson Disease
National Institute of Neurological Disorders and Stroke
Chronic Pain
Opioid Analgesics
Opiate Alkaloids
Brain
Back Pain
Center for chronic pain and drug abuse
Apkarian, A., Awatramani, R., Drenan, R. M., Graves, S. M., Griffith, J. W., Huang, L., Jovasevic, V., Martina, M., Miller, R. J., Parrish, T. B., Procissi, D., Radulovic, J., Rodes, M. E., Schnitzer, T. J. & Surmeier Jr, D. J.
National Institute on Drug Abuse
9/1/18 → 6/30/23
Project: Research project
Chronic Pain
Substance-Related Disorders
Opioid Analgesics
Opiate Alkaloids
Brain
Research Output 1985 2019
Cholinergic Interneurons Amplify Thalamostriatal Excitation of Striatal Indirect Pathway Neurons in Parkinson's Disease Models
Tanimura, A., Du, Y., Kondapalli, J., Wokosin, D. L. & Surmeier Jr, D. J., Feb 6 2019, In : Neuron. 101, 3, p. 444-458.e6Research output: Contribution to journal › Article
Intralaminar Thalamic Nuclei
Corpus Striatum
Interneurons
Cholinergic Agents
Parkinson Disease
Characterization of CNTNAP2 nanostructures on interneuronal dendrites
Gao, R., Piguel, N. H., Melendez-Zaidi, A. E., Martin-de-Saavedra, M. D., Yoon, S., Forrest, M. P., Myczek, K., Zhang, G., Russell, T. A., Csernansky, J. G., Surmeier Jr, D. J. & Penzes, P., Sep 1 2018, In : Molecular Psychiatry. 23, 9, 1 p.Research output: Contribution to journal › Article
Nanostructures
Dendrites
CNTNAP2 stabilizes interneuron dendritic arbors through CASK
Gao, R., Piguel, N. H., Melendez-Zaidi, A. E., Martin-de-Saavedra, M. D., Yoon, S., Forrest, M. P., Myczek, K., Zhang, G., Russell, T. A., Csernansky, J. G., Surmeier Jr, D. J. & Penzes, P., Apr 2 2018, (Accepted/In press) In : Molecular Psychiatry. p. 1-19 19 p.Research output: Contribution to journal › Article
Contactins
Calcium-Calmodulin-Dependent Protein Kinases
Protein-Serine-Threonine Kinases
Interneurons
Knockout Mice
Determinants of dopaminergic neuron loss in Parkinson's disease
Surmeier Jr, D. J., Jan 1 2018, (Accepted/In press) In : FEBS Journal.Research output: Contribution to journal › Article
Dopaminergic Neurons
Neurons
Parkinson Disease
Pathology
Synucleins
Striatal cholinergic interneurons and Parkinson's disease
Tanimura, A., Pancani, T., Lim, S. A. O., Tubert, C., Melendez, A. E., Shen, W. & Surmeier Jr, D. J., May 1 2018, In : European Journal of Neuroscience. 47, 10, p. 1148-1158 11 p.Research output: Contribution to journal › Review article
Corpus Striatum
Interneurons
Cholinergic Agents
Parkinson Disease
Optogenetics