Grants per year
Personal profile
Research Interests
The neuronal activity underlying mammalian spatial navigation represents one of the most striking examples of behavioral correlation in the brain. Professor Dombeck is interested in the cellular and circuit mechanisms responsible for the neuronal activity that allows mammals to navigate and find their way to specific destinations. To accomplish this, his research team develops and applies novel optical and genetic techniques to perform cellular and subcellular resolution imaging and manipulation of neuronal population activity in mice navigating in virtual reality environments. By understanding the navigation circuitry, they hope to extract general principles about neuronal population dynamics in behaving mammals.
Education/Academic qualification
Biophysics, PhD, Cornell University
… → 2005
Physics, MS, Cornell University
… → 2003
Physics, BS, University of Illinois at Urbana-Champaign
… → 2000
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Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Predoctoral and Postdoctoral Training Program in Aging and Dementia
Vassar, R. J., Weintraub, S., Allada, R., Bevan, M. D., Caraveo Piso, G., Carvill, G. L., Chan, S., Contractor, A., Disterhoft, J. F., Dombeck, D. A., Dong, H., Ferreira, A. B., Flanagan, M. E., Gefen, T. D., Geula, C., Gratton, C., He, C., Kahnt, T., Kalb, R. G., Kennedy, A., Kessler, J., Kiskinis, E., Klein, W. L., Kozorovitskiy, Y., Krainc, D., Li, L., Mazzulli, J., Mesulam, M., Miller, R. J., Morimoto, R. I., Opal, P., Ozdinler, H., Paller, K., Parisiadou, L., Penzes, P., Pinto, L., Prakriya, M., Reber, P. J., Roberts, A. L., Rogalski, E., Savas, J. N., Surmeier Jr, D. J., Swanson, G. T., Voss, J. L., Zee, P. C. & Zelano, C.
5/1/22 → 4/30/27
Project: Research project
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Interval Timing as a Window into Brainwide Dynamics
Brain & Behavior Research Foundation
1/15/22 → 1/14/24
Project: Research project
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Dombeck Subproject: Redefining PD pathophysiology mechanisms in the context of heterogeneous
Michael J. Fox Foundation for Parkinson's Research
11/1/21 → 10/31/24
Project: Research project
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NCS-FO: The Biology and Technology of Online Planning
MacIver, M. A. & Dombeck, D. A.
9/1/21 → 8/31/25
Project: Research project
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Behavior determines the hippocampal spatial mapping of a multisensory environment
Radvansky, B. A., Oh, J. Y., Climer, J. R. & Dombeck, D. A., Aug 3 2021, In: Cell reports. 36, 5, 109444.Research output: Contribution to journal › Article › peer-review
Open Access8 Scopus citations -
Information theoretic approaches to deciphering the neural code with functional fluorescence imaging
Climer, J. R. & Dombeck, D. A., Sep 1 2021, In: eNeuro. 8, 5, ENEURO.0266-21.2021.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
Sox6 expression distinguishes dorsally and ventrally biased dopamine neurons in the substantia nigra with distinctive properties and embryonic origins
Pereira Luppi, M., Azcorra, M., Caronia-Brown, G., Poulin, J. F., Gaertner, Z., Gatica, S., Moreno-Ramos, O. A., Nouri, N., Dubois, M., Ma, Y. C., Ramakrishnan, C., Fenno, L., Kim, Y. S., Deisseroth, K., Cicchetti, F., Dombeck, D. A. & Awatramani, R., Nov 9 2021, In: Cell reports. 37, 6, 109975.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
The functional organization of excitatory synaptic input to place cells
Adoff, M. D., Climer, J. R., Davoudi, H., Marvin, J. S., Looger, L. L. & Dombeck, D. A., Dec 1 2021, In: Nature communications. 12, 1, 3558.Research output: Contribution to journal › Article › peer-review
Open Access9 Scopus citations -
Inactivation of the Medial Entorhinal Cortex Selectively Disrupts Learning of Interval Timing
Heys, J. G., Wu, Z., Allegra Mascaro, A. L. & Dombeck, D. A., Sep 22 2020, In: Cell reports. 32, 12, 108163.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations