Grants per year
Personal profile
Research Interests
My special interests are focused on peripheral neuropathies, specifically Painful Diabetic Neuropathy, peripheral neuropathies as complication of systemic diseases including rheumatologic conditions, sarcoidosis and amyloidosis, hereditary neuropathies including Charcot-Marie-Tooth Disease, chemotherapy induced neuropathies.
Certifications and Licenses
Neurology |
Training Experience
2008 | Internship, Northwestern University, McGaw Medical Center (Evanston Northwestern Healthcare) |
2011 | Residency, Northwestern University, McGaw Medical Center |
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
PhD, Neuroscience, University of Milan
… → 2003
MD, Medicine, University of Milan
… → 1994
Research interests keywords
- Neuromuscular Disorders
- Peripheral Neuropathy
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Collaborations and top research areas from the last five years
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EN21-01, A Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Assess the Safety and Efficacy of 80 mg daily of NRD135S.E1 Versus Placebo in Adult and Elderly Participants with Painful Diabetic Peripheral Neuropathy (SERENDIPITY-1)
Menichella, D. M. (PD/PI), Menichella, D. M. (PD/PI) & Menichella, D. M. (PD/PI)
Massachusetts General Hospital, National Institute of Neurological Disorders and Stroke
11/1/22 → 1/31/26
Project: Research project
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Menichella Subproject Neuron-Keratinocyte Communication in the Epidermis in Normal and Diabetic Wound Healing
Menichella, D. M. (Subproject PI) & Menichella, D. M. (Subproject PI)
National Institute of Arthritis and Musculoskeletal and Skin Diseases
9/11/20 → 6/30/25
Project: Research project
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Orbitrap Eclipse Mass Spectrometer for Northwestern University Neuroproteomic Collaboration Hub
Savas, J. N. (PD/PI), Caraveo Piso, G. (Other), Contractor, A. (Other), Disterhoft, J. F. (Other), Duncan, F. E. (Other), Foltz, D. R. (Other), Goel, R. (Other), Kafader, J. O. (Other), Kalb, R. G. (Other), Kelleher, N. L. (Other), Kiskinis, E. (Other), Krainc, D. (Other), Mendillo, M. L. (Other), Menichella, D. M. (Other), Penzes, P. (Other), Smith, G. A. (Other), Surmeier Jr, D. J. (Other), Vassar, R. J. (Other), Walsh, D. (Other) & Zelano, C. (Other)
Office of the Director, National Institutes of Health
3/1/23 → 2/29/24
Project: Research project
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Clinical Research Sites for the Network of Excellence in Neuroscience Clinical Trials (NEXT Sites)
Simuni, T. (PD/PI), Roth, E. J. (Co-Investigator), Sorond, F. A. (Co-Investigator), Brent, J. R. (Other), Gertler, T. S. (Other) & Menichella, D. M. (Other)
National Institute of Neurological Disorders and Stroke
7/1/18 → 7/31/23
Project: Research project
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Cellular and Molecular Role of CXCR4 signaling in Painful Diabetic Neuropathy
Menichella, D. M. (PD/PI) & Miller, R. J. (Co-Investigator)
National Institute of Neurological Disorders and Stroke
12/1/17 → 11/30/22
Project: Research project
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A call to action for peripheral neuropathy research funding—Time to consolidate funding under one NIH initiative?
Eid, S. A., Townsend, K. L., Spallone, V., Menichella, D. M., Koubek, E. J. & Feldman, E. L., Mar 2025, In: Journal of the Peripheral Nervous System. 30, 1, e12681.Research output: Contribution to journal › Letter › peer-review
Open Access1 Scopus citations -
Keratinocyte-derived extracellular vesicles in painful diabetic neuropathy
Coy-Dibley, J., Jayaraj, N. D., Ren, D., Pacifico, P., Belmadani, A., Wang, Y. Z., Gebis, K. K., Savas, J. N., Paller, A. S., Miller, R. J. & Menichella, D. M., Jan 1 2025, In: Neurobiology of Pain. 17, 100176.Research output: Contribution to journal › Article › peer-review
Open Access -
Molecular mechanisms of neuropathic pain
Pacifico, P. & Menichella, D. M., Jan 2024, Neuropathic Pain. Rosner, J. & Karlsson, P. (eds.). Academic Press Inc, p. 279-309 31 p. (International Review of Neurobiology; vol. 179).Research output: Chapter in Book/Report/Conference proceeding › Chapter
1 Scopus citations -
The Mas-related G protein-coupled receptor d (Mrgprd) mediates pain hypersensitivity in painful diabetic neuropathy
George, D. S., Jayaraj, N. D., Pacifico, P., Ren, D., Sriram, N., Miller, R. E., Malfait, A. M., Miller, R. J. & Menichella, D. M., May 1 2024, In: Pain. 165, 5, p. 1154-1168 15 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Misregulation of mitochondria lysosome contact dynamics in Charcot Marie Tooth Type 2B disease Rab7 mutant sensory peripheral neurons
Wong, Y. C., Jayaraj, N. D., Belton, T. B., Shum, G. C., Ball, H. E., Ren, D., Tadenev, A. L. D., Krainc, D., Burgess, R. W. & Menichella, D. M., 2023, In: Proceedings of the National Academy of Sciences of the United States of America. 120, 44, e2313010120.Research output: Contribution to journal › Article › peer-review
Open Access11 Scopus citations
Datasets
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Gene Expression in Mutant P0 Cre Dicer Mouse Sciatic Nerves
Yun, B. (Contributor), Anderegg, A. (Contributor), Menichella, D. (Contributor), Wrabetz, L. (Contributor) & Awatramani, R. (Contributor), ArrayExpress, 2010
https://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-16741
Dataset