Danielle Tullman Ercek

  • 1401 Citations
20032023
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Personal profile

Research Interests

My group is interested in controlling the movement of materials across biological membranes, with a goal of enabling and enhancing the production of pharmaceuticals, biofuels, and materials in microbes. Manipulating the transport of electrons, small molecules, and even signals across these cellular boundaries is a vital component of most synthetic biology applications, and we are developing the tools and methods to engineer membrane proteins and other protein superstructures to meet this grand challenge.

Education/Academic qualification

Chemical Engineering, PhD, The University of Texas at Austin

… → 2006

Chemical Engineering, Illinois Institute of Technology

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Grants 2016 2023

Metabolic Networks and Pathways
Propylene Glycols
Synthetic Biology
Metabolic Engineering
Bioengineering
Biofuels
Metabolism
Recycling
Enzymes
Metabolic engineering
Metabolic Networks and Pathways
Synthetic Biology
Metabolic Engineering
1-Butanol
Terpenes
biology
networking
student
engineering
communication

Research Output 2003 2019

Cargo encapsulation in bacterial microcompartments: Methods and analysis

Nichols, T. M., Kennedy, N. W. & Ercek, D. T., Jan 1 2019, Methods in Enzymology. Academic Press Inc., p. 155-186 32 p. (Methods in Enzymology; vol. 617).

Research output: Chapter in Book/Report/Conference proceedingChapter

Propylene Glycol
Encapsulation
Scaffolds
Organizations
Metabolic engineering
2 Citations (Scopus)

Experimental Evaluation of Coevolution in a Self-Assembling Particle

Hartman, E. C., Lobba, M. J., Favor, A. H., Robinson, S. A., Francis, M. B. & Ercek, D. T., Mar 19 2019, In : Biochemistry. 58, 11, p. 1527-1538 12 p.

Research output: Contribution to journalArticle

Viruses
Virion
Self assembly
Mutation
Proteins

Learning from protein fitness landscapes: a review of mutability, epistasis, and evolution

Hartman, E. C. & Ercek, D. T., Apr 1 2019, In : Current Opinion in Systems Biology. 14, p. 25-31 7 p.

Research output: Contribution to journalReview article

Epistasis
Fitness Landscape
Learning
Proteins
Protein
1 Citation (Scopus)

Systematic Engineering of a Protein Nanocage for High-Yield, Site-Specific Modification

Brauer, D. D., Hartman, E. C., Bader, D. L. V., Merz, Z. N., Ercek, D. T. & Francis, M. B., Mar 6 2019, In : Journal of the American Chemical Society. 141, 9, p. 3875-3884 10 p.

Research output: Contribution to journalArticle

Protein Engineering
Proteins
Virion
Libraries
Levivirus

An estimate is worth about a thousand experiments: Using order-of-magnitude estimates to identify cellular engineering targets

Metcalf, K. J., Slininger Lee, M. F., Jakobson, C. M. & Ercek, D. T., Aug 30 2018, In : Microbial Cell Factories. 17, 1, 135.

Research output: Contribution to journalReview article

Cell Engineering
Intuition
Biological systems
Drug products
Glucose