Grants per year
Personal profile
Research Interests
My group is interested in controlling the movement of materials across biological membranes, with a goal of enabling and enhancing the production of pharmaceuticals, biofuels, and materials in microbes. Manipulating the transport of electrons, small molecules, and even signals across these cellular boundaries is a vital component of most synthetic biology applications, and we are developing the tools and methods to engineer membrane proteins and other protein superstructures to meet this grand challenge.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Chemical Engineering, PhD, University of Texas at Austin
… → 2006
Chemical Engineering, Illinois Institute of Technology
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Collaborations and top research areas from the last five years
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DMREF: High-Throughput Design of Protein-based Biomaterials through SimulationInformed Directed Evolution
Wang, M. (PD/PI), Keten, S. (Co-Investigator) & Tullman-Ercek, D. (Co-Investigator)
10/1/24 → 9/30/27
Project: Research project
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Chemical and Biological Engineering
Dunn, J. B. (Co-Investigator), Lucks, J. B. (Co-Investigator) & Tullman-Ercek, D. (Co-Investigator)
7/1/24 → 6/30/29
Project: Research project
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APTO: Measuring, Understanding, Predicting, and Accelerating Technology Outcomes
Wang, D. (PD/PI), Cao, J. (Co-PD/PI), Cao, J. (Co-PD/PI), Jones, B. (Co-PD/PI), Dunn, J. B. (Other), Dunn, J. B. (Other), Eskreis-Winkler, L. (Other), Hersam, M. (Other), Hersam, M. (Other), Lucks, J. B. (Other), Lucks, J. B. (Other), Sangwan, V. K. (Other), Tullman-Ercek, D. (Other) & Tullman-Ercek, D. (Other)
7/1/24 → 6/30/29
Project: Research project
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Tullman-Ercek: Northwestern University Materials Research Science and Engineering Center
Tullman-Ercek, D. (Co-PD/PI) & Tullman-Ercek, D. (Co-PD/PI)
9/1/23 → 8/31/29
Project: Research project
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The Army Synthetic Biology Center for Predictive Materials Design (PreMaDe)
Tullman-Ercek, D. (PD/PI), Tullman-Ercek, D. (PD/PI), Tullman-Ercek, D. (PD/PI), Gianneschi, N. (Co-PD/PI), Gianneschi, N. (Co-PD/PI), Gianneschi, N. (Co-PD/PI), Kamat, N. P. (Co-PD/PI), Kamat, N. P. (Co-PD/PI), Kamat, N. P. (Co-PD/PI), Lucks, J. B. (Co-PD/PI), Lucks, J. B. (Co-PD/PI), Lucks, J. B. (Co-PD/PI) & Jewett, M. C. (Co-Investigator)
9/30/22 → 9/29/27
Project: Research project
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Encapsulation of Select Violacein Pathway Enzymes in the 1,2-Propanediol Utilization Bacterial Microcompartment to Divert Pathway Flux
Palmero, B. J., Gamero, E., Mangan, N. M. & Tullman-Ercek, D., Sep 2025, In: Metabolic Engineering. 91, p. 91-102Research output: Contribution to journal › Article › peer-review
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Engineering bacterial microcompartments to enable sustainable microbial bioproduction from C1 greenhouse gases
Johnson, E. R., Joseph, M. R. & Tullman-Ercek, D., Jun 2025, In: Current Opinion in Biotechnology. 93, 103299.Research output: Contribution to journal › Review article › peer-review
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Signal sequences target enzymes and structural proteins to bacterial microcompartments and are critical for microcompartment formation
Johnson, E. R., Kennedy, N. W., Mills, C. E., Liang, S., Chandrasekar, S., Nichols, T. M., Rybnicky, G. A., Tullman-Ercek, D. & Ellermeier, C. D. (Editor), Apr 16 2025, In: mSphere.Research output: Contribution to journal › Article › peer-review
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Characterization and engineering of the type 3 secretion system needle monomer from Salmonella through the construction and screening of a comprehensive mutagenesis library
Burdette, L. A., Leach, S. A., Kennedy, N., Ikwuagwu, B. C., Summers, J. S. & Tullman-Ercek, D., Aug 2024, In: mSphere. 9, 8Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Deconstructing synthetic biology across scales: a conceptual approach for training synthetic biologists
Karim, A. S., Brown, D. M., Archuleta, C. M., Grannan, S., Aristilde, L., Goyal, Y., Leonard, J. N., Mangan, N. M., Prindle, A., Rocklin, G. J., Tyo, K. J., Zoloth, L. S., Jewett, M. C., Calkins, S. C., Kamat, N. P., Tullman-Ercek, D. & Lucks, J. B., Dec 2024, In: Nature communications. 15, 1, 5425.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations
Datasets
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An optimized growth medium for increased recombinant protein secretion titer via the type III secretion system
Burdette, L. A. (Creator), Wong, H. T. (Creator) & Tullman-Ercek, D. (Creator), figshare, 2021
DOI: 10.6084/m9.figshare.c.5306002, https://springernature.figshare.com/collections/An_optimized_growth_medium_for_increased_recombinant_protein_secretion_titer_via_the_type_III_secretion_system/5306002
Dataset
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MOESM1 of A Pseudomonas putida efflux pump acts on short-chain alcohols
Basler, G. (Creator), Thompson, M. (Creator), Tullman-Ercek, D. (Creator) & Keasling, J. (Creator), figshare, 2018
DOI: 10.6084/m9.figshare.6254279, https://springernature.figshare.com/articles/MOESM1_of_A_Pseudomonas_putida_efflux_pump_acts_on_short-chain_alcohols/6254279
Dataset
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MOESM3 of A Pseudomonas putida efflux pump acts on short-chain alcohols
Basler, G. (Creator), Thompson, M. (Creator), Tullman-Ercek, D. (Creator) & Keasling, J. (Creator), figshare, 2018
DOI: 10.6084/m9.figshare.6254315, https://springernature.figshare.com/articles/MOESM3_of_A_Pseudomonas_putida_efflux_pump_acts_on_short-chain_alcohols/6254315
Dataset
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The structure of the S37P MS2 viral capsid assembly.
Asensio, M. A. (Contributor), Morella, N. M. (Contributor), Jakobson, C. M. (Contributor), Hartman, E. C. (Contributor), Glasgow, J. E. (Contributor), Sankaran, B. (Contributor), Zwart, P. H. (Contributor) & Tullman-Ercek, D. (Contributor), Protein Data Bank (PDB), Sep 7 2016
DOI: 10.2210/pdb4ZOR/pdb, https://www.wwpdb.org/pdb?id=pdb_00004zor
Dataset
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A Pseudomonas putida efflux pump acts on short-chain alcohols
Basler, G. (Creator), Thompson, M. (Creator), Tullman-Ercek, D. (Creator) & Keasling, J. (Creator), figshare, 2018
DOI: 10.6084/m9.figshare.c.4097201.v1, https://springernature.figshare.com/collections/A_Pseudomonas_putida_efflux_pump_acts_on_short-chain_alcohols/4097201/1
Dataset