Grants per year
Personal profile
Research Interests
My current research includes the following: 1. Evaluation of new treatments for Opioid Related Constipation 2. Therapeutic trials for the treatment of constipation in adults with cystic fibrosis 3. Prevalence and quality of life assessments in individuals with refractory constipation and fecal incontinence 4. Use of newer pharmaceuticals and endoscopic modalities for treating gastroparesis 5. Use of virtual reality for treating functional GI disorders 6. Phase II/III pharmaceutical trials for functional GI disorders--predominately IBS
Gastrointestinal motility disorders and pelvic floor disorders including but not limited to Constipation/Fecal Incontinence/Irritable Bowel Syndrome/Dyspepsia/Gastroparesis/Opioid related bowel dysfunction as well as complications of systemic motility disorders with an emphasis on Scleroderma.
Certifications and Licenses
| Gastroenterology | |
| Internal Medicine |
Training Experience
| 2005 | Residency, University of Michigan Health System |
| 2008 | Fellowship, University of Michigan Health System |
Education/Academic qualification
MD, University of Chicago
… → 2002
Research interests
- Pelvic Floor Disorders and Surgery
Fingerprint Dive into the research topics where Darren M Brenner is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
- 2 Similar Profiles
Irritable Bowel Syndrome
Medicine & Life Sciences
Constipation
Medicine & Life Sciences
Opioid Analgesics
Medicine & Life Sciences
Placebos
Medicine & Life Sciences
Therapeutics
Medicine & Life Sciences
Cognitive Therapy
Medicine & Life Sciences
Randomized Controlled Trials
Medicine & Life Sciences
Systemic Scleroderma
Medicine & Life Sciences
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Grants 2008 2015
- 2 Finished
Antidepressent Therapy for Functional Dyspepsia
Mayo Clinic, National Institute of Diabetes, Digestive and Kidney Diseases
8/1/10 → 7/31/11
Project: Research project
Self-administered CBT for IBS: A Multicenter Trial
State University of New York at Buffalo, National Institute of Diabetes, Digestive and Kidney Diseases
5/15/08 → 4/30/15
Project: Research project
Research Output 2000 2019
A Randomized, Multicenter, Prospective, Crossover, Open-Label Study of Factors Associated with Patient Preferences for Naloxegol or PEG 3350 for Opioid-Induced Constipation
Brenner, D. M., Hu, Y., Datto, C., Creanga, D. & Camilleri, M., Jun 1 2019, In : American Journal of Gastroenterology. 114, 6, p. 954-963 10 p.Research output: Contribution to journal › Article
Patient Preference
Constipation
Opioid Analgesics
Therapeutics
Laxatives
3
Citations
(Scopus)
Durability and Decay of Treatment Benefit of Cognitive Behavioral Therapy for Irritable Bowel Syndrome: 12-Month Follow-Up
Lackner, J. M., Jaccard, J., Radziwon, C. D., Firth, R. S., Gudleski, G. D., Hamilton, F., Katz, L. A., Keefer, L., Krasner, S. S., Ma, C. X., Sitrin, M. D. & Brenner, D. M., Feb 1 2019, In : American Journal of Gastroenterology. 114, 2, p. 330-338 9 p.Research output: Contribution to journal › Article
Irritable Bowel Syndrome
Cognitive Therapy
Therapeutics
Education
Maintenance
1
Citation
(Scopus)
Efficacy and Safety of Eluxadoline in Patients With Irritable Bowel Syndrome With Diarrhea Who Report Inadequate Symptom Control With Loperamide: RELIEF Phase 4 Study
Brenner, D. M., Sayuk, G. S., Gutman, C. R., Jo, E., Elmes, S. J. R., Liu, L. W. C. & Cash, B. D., Sep 1 2019, In : American Journal of Gastroenterology. 114, 9, p. 1502-1511 10 p.Research output: Contribution to journal › Article
Loperamide
Irritable Bowel Syndrome
Diarrhea
Safety
Abdominal Pain
7
Citations
(Scopus)
Efficacy of pharmacological therapies for the treatment of opioid-induced constipation: Systematic review and network meta-analysis
Luthra, P., Burr, N. E., Brenner, D. M. & Ford, A. C., Mar 1 2019, In : Gut. 68, 3, p. 434-444 11 p.Research output: Contribution to journal › Article
Constipation
Opioid Analgesics
Pharmacology
Naloxone
Therapeutics
Factors Associated With Efficacy of Cognitive Behavior Therapy vs Education for Patients With Irritable Bowel Syndrome
IBS Outcome Study Research Group, Jul 1 2019, In : Clinical Gastroenterology and Hepatology. 17, 8, p. 1500-1508.e3Research output: Contribution to journal › Article
Irritable Bowel Syndrome
Cognitive Therapy
Patient Education
Anxiety
Education