Darren M Brenner

Associate Professor, Medicine, Gastroenterology Division
Associate Professor, Surgery, Gastrointestinal/Endocrinology Division

Phone+1 312 695 5620
Emaildarren-brenner@northwestern.edu

Source: Scopus

Research activity per year

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Personal profile

Research Interests

My current research includes the following: 1. Evaluation of new treatments for Opioid Related Constipation 2. Therapeutic trials for the treatment of constipation in adults with cystic fibrosis 3. Prevalence and quality of life assessments in individuals with refractory constipation and fecal incontinence 4. Use of newer pharmaceuticals and endoscopic modalities for treating gastroparesis 5. Use of virtual reality for treating functional GI disorders 6. Phase II/III pharmaceutical trials for functional GI disorders--predominately IBS

Gastrointestinal motility disorders and pelvic floor disorders including but not limited to Constipation/Fecal Incontinence/Irritable Bowel Syndrome/Dyspepsia/Gastroparesis/Opioid related bowel dysfunction as well as complications of systemic motility disorders with an emphasis on Scleroderma.

Certifications and Licenses

	Gastroenterology
	Internal Medicine

Training Experience

2005	Residency, University of Michigan Health System
2008	Fellowship, University of Michigan Health System

Education/Academic qualification

MD, The University of Chicago

… → 2002

Medicine, MD, University of Chicago

… → 2002

Research interests

Pelvic Floor Disorders and Surgery

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1 Active
2 Finished

Open-Label Assessment of the Efficacy of Atrantil in the Treatment of Methane-Predominate Intestinal Bacterial Overgrowth.
Brenner, D. M. & Cai, J. X.
Northwestern Memorial Hospital, Digestive Health Foundation
6/1/20 → 12/31/21
Project: Research project
Antidepressent Therapy for Functional Dyspepsia
Brenner, D. M. & Yun, L. H.
Mayo Clinic, National Institute of Diabetes and Digestive and Kidney Diseases
8/1/10 → 7/31/11
Project: Research project
Self-administered CBT for IBS: A Multicenter Trial
Brenner, D. M.
SUNY Buffalo, National Institute of Diabetes and Digestive and Kidney Diseases
5/15/08 → 4/30/15
Project: Research project

832 Citations
29 Article
8 Review article
5 Letter
3 Comment/debate
More
- 1 Chapter
- 1 Editorial

ACG Clinical Guideline: Management of Irritable Bowel Syndrome
Lacy, B. E., Pimentel, M., Brenner, D. M., Chey, W. D., Keefer, L. A., Long, M. D. & Moshiree, B., Jan 1 2021, In: The American journal of gastroenterology. 116, 1, p. 17-44 28 p.
Research output: Contribution to journal › Article › peer-review

Open Access
1 Scopus citations
Current US Food and Drug Administration-Approved Pharmacologic Therapies for the Treatment of Irritable Bowel Syndrome with Diarrhea
Brenner, D. M. & Sayuk, G. S., Jan 1 2020, In: Advances in Therapy. 37, 1, p. 83-96 14 p.
Research output: Contribution to journal › Review article › peer-review

Open Access
5 Scopus citations
Efficacy and safety of linaclotide for opioid-induced constipation in patients with chronic noncancer pain syndromes from a phase 2 randomized study
Brenner, D. M., Argoff, C. E., Fox, S. M., Bochenek, W., DʼAstoli, P., Blakesley, R. E., Reasner, D. S., OʼDea, C. R. & Cash, B. D., May 1 2020, In: Pain. 161, 5, p. 1027-1036 10 p.
Research output: Contribution to journal › Article › peer-review

Open Access
How to Manage Opioid-Related Constipation in Individuals with Chronic Nonmalignant Pain Syndromes
Brenner, D. M., Barrett-Englert, M. & Cash, B. D., Mar 1 2020, In: American Journal of Gastroenterology. 115, 3, p. 307-310 4 p.
Research output: Contribution to journal › Article › peer-review

Open Access
Major Trends in Gastroenterology and Hepatology between 2010 and 2019: An Overview of Advances from the Past Decade Selected by the Editorial Board of the American Journal of Gastroenterology
Bajaj, J. S., Brenner, D. M., Cai, Q., Cash, B. D., Crowell, M., Dibaise, J., Gallegos-Orozco, J. F., Gardner, T. B., Gyawali, C. P., Ha, C., Holtmann, G., Jamil, L. H., Kaplan, G. G., Karsan, H. A., Kinoshita, Y., Lebwohl, B., Leontiadis, G. I., Lichtenstein, G. R., Longstreth, G. F., Muthusamy, V. R. & 14 others, Oxentenko, A. S., Pimentel, M., Pisegna, J. R., Rubenstein, J. H., Russo, M. W., Saini, S. D., Samadder, N. J., Shaukat, A., Simren, M., Stevens, T., Valdovinos, M., Vargas, H., Spiegel, B. & Lacy, B. E., Jul 1 2020, In: American Journal of Gastroenterology. 115, 7, p. 1007-1018 12 p.
Research output: Contribution to journal › Review article › peer-review

Open Access