Grants per year
Personal profile
Research Interests
My current research includes the following: 1. Evaluation of new treatments for Opioid Related Constipation 2. Therapeutic trials for the treatment of constipation in adults with cystic fibrosis 3. Prevalence and quality of life assessments in individuals with refractory constipation and fecal incontinence 4. Use of newer pharmaceuticals and endoscopic modalities for treating gastroparesis 5. Use of virtual reality for treating functional GI disorders 6. Phase II/III pharmaceutical trials for functional GI disorders--predominately IBS
Gastrointestinal motility disorders and pelvic floor disorders including but not limited to Constipation/Fecal Incontinence/Irritable Bowel Syndrome/Dyspepsia/Gastroparesis/Opioid related bowel dysfunction as well as complications of systemic motility disorders with an emphasis on Scleroderma.
Certifications and Licenses
| Gastroenterology | |
| Internal Medicine |
Training Experience
| 2005 | Residency, University of Michigan Health System |
| 2008 | Fellowship, University of Michigan Health System |
Education/Academic qualification
MD, The University of Chicago
… → 2002
Research interests
- Pelvic Floor Disorders and Surgery
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Grants
Open-Label Assessment of the Efficacy of Atrantil in the Treatment of Methane-Predominate Intestinal Bacterial Overgrowth.
7/1/20 → 6/30/21
Project: Research project
Antidepressent Therapy for Functional Dyspepsia
Mayo Clinic, National Institute of Diabetes and Digestive and Kidney Diseases
8/1/10 → 7/31/11
Project: Research project
Self-administered CBT for IBS: A Multicenter Trial
SUNY Buffalo, National Institute of Diabetes and Digestive and Kidney Diseases
5/15/08 → 4/30/15
Project: Research project
Research Output
Current US Food and Drug Administration-Approved Pharmacologic Therapies for the Treatment of Irritable Bowel Syndrome with Diarrhea
Brenner, D. M. & Sayuk, G. S., Jan 1 2020, In : Advances in Therapy. 37, 1, p. 83-96 14 p.Research output: Contribution to journal › Review article
Open Access
3
Scopus
citations
Efficacy and safety of linaclotide for opioid-induced constipation in patients with chronic noncancer pain syndromes from a phase 2 randomized study
Brenner, D. M., Argoff, C. E., Fox, S. M., Bochenek, W., DʼAstoli, P., Blakesley, R. E., Reasner, D. S., OʼDea, C. R. & Cash, B. D., May 1 2020, In : Pain. 161, 5, p. 1027-1036 10 p.Research output: Contribution to journal › Article
Open Access
How to Manage Opioid-Related Constipation in Individuals with Chronic Nonmalignant Pain Syndromes
Brenner, D. M., Barrett-Englert, M. & Cash, B. D., Mar 1 2020, In : American Journal of Gastroenterology. 115, 3, p. 307-310 4 p.Research output: Contribution to journal › Article
Open Access
Response to Black et al.
Brenner, D. M., Sayuk, G. S., Gutman, C. R., Jo, E., Elmes, S. J. R., Liu, L. W. C. & Cash, B. D., Mar 1 2020, In : American Journal of Gastroenterology. 115, 3, p. 484-485 2 p.Research output: Contribution to journal › Letter
A Randomized, Multicenter, Prospective, Crossover, Open-Label Study of Factors Associated with Patient Preferences for Naloxegol or PEG 3350 for Opioid-Induced Constipation
Brenner, D. M., Hu, Y., Datto, C., Creanga, D. & Camilleri, M., Jun 1 2019, In : American Journal of Gastroenterology. 114, 6, p. 954-963 10 p.Research output: Contribution to journal › Article
2
Scopus
citations