Grants per year
Personal profile
Research Interests
Gastrointestinal motility disorders and pelvic floor disorders including but not limited to Constipation/Fecal Incontinence/Irritable Bowel Syndrome/Dyspepsia/Gastroparesis/Opioid related bowel dysfunction as well as complications of systemic motility disorders with an emphasis on Scleroderma.
My current research includes the following: 1. Evaluation of new treatments for Opioid Related Constipation 2. Therapeutic trials for the treatment of constipation in adults with cystic fibrosis 3. Prevalence and quality of life assessments in individuals with refractory constipation and fecal incontinence 4. Use of newer pharmaceuticals and endoscopic modalities for treating gastroparesis 5. Use of virtual reality for treating functional GI disorders 6. Phase II/III pharmaceutical trials for functional GI disorders--predominately IBS
Certifications and Licenses
| Internal Medicine | |
| Gastroenterology |
Training Experience
| 2005 | Residency, University of Michigan Health System |
| 2008 | Fellowship, University of Michigan Health System |
Education/Academic qualification
MD, University of Chicago
… → 2002
Keywords
- Pelvic Floor Disorders and Surgery
Fingerprint Fingerprint is based on mining the text of the experts' scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.
- 2 Similar Profiles
Irritable Bowel Syndrome
Medicine & Life Sciences
Constipation
Medicine & Life Sciences
Opioid Analgesics
Medicine & Life Sciences
Therapeutics
Medicine & Life Sciences
Randomized Controlled Trials
Medicine & Life Sciences
Placebos
Medicine & Life Sciences
Systemic Scleroderma
Medicine & Life Sciences
Chronic Pain
Medicine & Life Sciences
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Grants 2008 2015
- 2 Finished
Antidepressent Therapy for Functional Dyspepsia
Mayo Clinic, National Institute of Diabetes, Digestive and Kidney Diseases
8/1/10 → 7/31/11
Project: Research project
Self-administered CBT for IBS: A Multicenter Trial
State University of New York at Buffalo, National Institute of Diabetes, Digestive and Kidney Diseases
5/15/08 → 4/30/15
Project: Research project
Research Output 2000 2019
2
Citations
(Scopus)
Efficacy of pharmacological therapies for the treatment of opioid-induced constipation: Systematic review and network meta-analysis
Luthra, P., Burr, N. E., Brenner, D. M. & Ford, A. C., Mar 1 2019, In : Gut. 68, 3, p. 434-444 11 p.Research output: Contribution to journal › Article
Constipation
Opioid Analgesics
Pharmacology
Naloxone
Therapeutics
1
Citation
(Scopus)
(Can't Get No) Patient Satisfaction the Predictive Power of Demographic, GI, and Psychological Factors in IBS Patients
Quigley, B. M., Sova, C. C., Brenner, D. M., Keefer, L. A., Sitrin, M. D., Radziwon, C. D., Krasner, S. S. & Lackner, J. M., Aug 1 2018, In : Journal of Clinical Gastroenterology. 52, 7, p. 614-621 8 p.Research output: Contribution to journal › Article
Irritable Bowel Syndrome
Patient Satisfaction
Demography
Psychology
Routine Diagnostic Tests
1
Citation
(Scopus)
Abnormal esophageal acid exposure on high-dose proton pump inhibitor therapy is common in systemic sclerosis patients
Stern, E. K., Carlson, D. A., Falmagne, S., Hoffmann, A. D., Carns, M., Pandolfino, J. E., Hinchcliff, M. E. & Brenner, D. M., Feb 1 2018, In : Neurogastroenterology and Motility. 30, 2, e13247.Research output: Contribution to journal › Article
Systemic Scleroderma
Proton Pump Inhibitors
Acids
Electric Impedance
Therapeutics
1
Citation
(Scopus)
Durability and Decay of Treatment Benefit of Cognitive Behavioral Therapy for Irritable Bowel Syndrome: 12-Month Follow-Up
Lackner, J. M., Jaccard, J., Radziwon, C. D., Firth, R. S., Gudleski, G. D., Hamilton, F., Katz, L. A., Keefer, L., Krasner, S. S., Ma, C. X., Sitrin, M. D. & Brenner, D. M., Jan 1 2018, (Accepted/In press) In : American Journal of Gastroenterology.Research output: Contribution to journal › Article
Irritable Bowel Syndrome
Cognitive Therapy
Therapeutics
Education
Maintenance
13
Citations
(Scopus)
Efficacy, safety, and tolerability of plecanatide in patients with irritable bowel syndrome with constipation: Results of two phase 3 randomized clinical trials
Brenner, D. M., Fogel, R., Dorn, S. D., Krause, R., Eng, P., Kirshoff, R., Nguyen, A., Crozier, R. A., Magnus, L. & Griffin, P. H., May 1 2018, In : American Journal of Gastroenterology. 113, 5, p. 735-745 11 p.Research output: Contribution to journal › Article
Phase III Clinical Trials
Irritable Bowel Syndrome
Constipation
Randomized Controlled Trials
Placebos