Grants per year
Personal profile
Research Interests
My current research includes the following: 1. Evaluation of new treatments for Opioid Related Constipation 2. Therapeutic trials for the treatment of constipation in adults with cystic fibrosis 3. Prevalence and quality of life assessments in individuals with refractory constipation and fecal incontinence 4. Use of newer pharmaceuticals and endoscopic modalities for treating gastroparesis 5. Use of virtual reality for treating functional GI disorders 6. Phase II/III pharmaceutical trials for functional GI disorders--predominately IBS
Gastrointestinal motility disorders and pelvic floor disorders including but not limited to Constipation/Fecal Incontinence/Irritable Bowel Syndrome/Dyspepsia/Gastroparesis/Opioid related bowel dysfunction as well as complications of systemic motility disorders with an emphasis on Scleroderma.
Certifications and Licenses
| Gastroenterology | |
| Internal Medicine |
Training Experience
| 2005 | Residency, University of Michigan Health System |
| 2008 | Fellowship, University of Michigan Health System |
Education/Academic qualification
Medicine, MD, University of Chicago
… → 2002
Research interests
- Pelvic Floor Disorders and Surgery
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Network
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Prot# APD371-202: A Phase 2, Multi-Center, Randomized, Double-Blind, Placebo-Controlled Parallel-Group Study to Evaluate the Safety, Tolerability, and Efficacy of Olorinab in Subjects with Irritable Bowel Syndrome Experiencing Abdominal Pain
DrugDev Inc., Arena Pharmaceuticals, Inc.
5/8/20 → 5/8/23
Project: Research project
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Antidepressent Therapy for Functional Dyspepsia
Mayo Clinic, National Institute of Diabetes and Digestive and Kidney Diseases
8/1/10 → 7/31/11
Project: Research project
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Self-administered CBT for IBS: A Multicenter Trial
SUNY Buffalo, National Institute of Diabetes and Digestive and Kidney Diseases
5/15/08 → 4/30/15
Project: Research project
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ACG Clinical Guideline: Management of Irritable Bowel Syndrome
Lacy, B. E., Pimentel, M., Brenner, D. M., Chey, W. D., Keefer, L. A., Long, M. D. & Moshiree, B., Jan 1 2021, In: The American journal of gastroenterology. 116, 1, p. 17-44 28 p.Research output: Contribution to journal › Article › peer-review
Open Access32 Scopus citations -
Baseline Predictors of Discontinuation of Prescription Drug Therapy for IBS-C: Cohort Analysis at an Integrated Healthcare System
Shah, E. D., Brenner, D. M. & Chen, V. L., 2021, (Accepted/In press) In: Digestive diseases and sciences.Research output: Contribution to journal › Article › peer-review
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Efficacy and Safety of Over-the-Counter Therapies for Chronic Constipation: An Updated Systematic Review
Rao, S. S. C. & Brenner, D. M., Jun 1 2021, In: The American journal of gastroenterology. 116, 6, p. 1156-1181 26 p.Research output: Contribution to journal › Article › peer-review
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Focus on Pharmacotherapy for Irritable Bowel Syndrome with Constipation
Liu, J. J. & Brenner, D. M., Sep 2021, In: Gastroenterology Clinics of North America. 50, 3, p. 639-653 15 p.Research output: Contribution to journal › Review article › peer-review
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Improved work productivity and health-related quality of life in patients with irritable bowel syndrome with diarrhea receiving eluxadoline following inadequate response to loperamide
Brenner, D. M., Sayuk, G. S., Abel, J. L. & Burslem, K., Apr 2021, In: Journal of Managed Care and Specialty Pharmacy. 27, 4, p. 469-477 9 p.Research output: Contribution to journal › Article › peer-review