Grants per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Integrative Biology, PhD, University of Southern California
… → 2015
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Dive into the research topics where David Gate is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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T cell specificity in Parkinson's disease hypothalamus Supplement
Gate, D. (PD/PI)
Michael J. Fox Foundation for Parkinson's Research
12/12/24 → 6/12/25
Project: Research project
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Anatomic, Pathologic, and Molecular Signatures of FTLD-TDP type C
Gefen, T. D. (PD/PI), Geula, C. (PD/PI), Mesulam, M.-M. (PD/PI), Barbieri, E. (Co-Investigator), Castellani, R. (Co-Investigator), Gate, D. (Co-Investigator), Jamshidi, P. (Co-Investigator) & Zhang, H. (Co-Investigator)
12/1/24 → 11/30/29
Project: Research project
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Gate Subproject
Gate, D. (Co-Investigator)
Michael J. Fox Foundation for Parkinson's Research
11/1/24 → 10/31/26
Project: Research project
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CAA-related inflammation as a model for Aβ immunotherapy side effects
Gate, D. (PD/PI) & van Olst, L. (Other)
1/1/24 → 12/31/25
Project: Research project
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Neuroimmunity in Alzheimer's disease
Gate, D. (PD/PI) & van Olst, L. (Other)
1/1/24 → 12/31/25
Project: Research project
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A single-cell atlas to map sex-specific gene-expression changes in blood upon neurodegeneration
Grandke, F., Fehlmann, T., Kern, F., Gate, D. M., Wolff, T. W., Leventhal, O., Channappa, D., Hirsch, P., Wilson, E. N., Meese, E., Liu, C., Shi, Q., Flotho, M., Li, Y., Chen, C., Yu, Y., Xu, J., Junkin, M., Wang, Z. & Wu, T. & 8 others, , Dec 2025, In: Nature communications. 16, 1, 1965.Research output: Contribution to journal › Article › peer-review
Open Access -
Clonally expanded, targetable, natural killer-like NKG7 T cells seed the aged spinal cord to disrupt myeloid-dependent wound healing
Kong, G., Song, Y., Yan, Y., Calderazzo, S. M., Saddala, M. S., De Labastida Rivera, F., Cherry, J. D., Eckman, N., Appel, E. A., Velenosi, A., Swarup, V., Kawaguchi, R., Ng, S. S., Kwon, B. K., Gate, D., Engwerda, C. R., Zhou, L. & Di Giovanni, S., Mar 5 2025, In: Neuron. 113, 5, p. 684-700.e8Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Correction to: Microglial mechanisms drive amyloid-β clearance in immunized patients with Alzheimer’s disease (Nature Medicine, (2025), 10.1038/s41591-025-03574-1)
van Olst, L., Simonton, B., Edwards, A. J., Forsyth, A. V., Boles, J., Jamshidi, P., Watson, T., Shepard, N., Krainc, T., Argue, B. M. R., Zhang, Z., Kuruvilla, J., Camp, L., Li, M., Xu, H., Norman, J. L., Cahan, J., Vassar, R., Chen, J. & Castellani, R. J. & 3 others, , 2025, (Accepted/In press) In: Nature Medicine.Research output: Contribution to journal › Comment/debate › peer-review
Open Access -
Microglial mechanisms drive amyloid-β clearance in immunized patients with Alzheimer’s disease
van Olst, L., Simonton, B., Edwards, A. J., Forsyth, A. V., Boles, J., Jamshidi, P., Watson, T., Shepard, N., Krainc, T., Argue, B. M. R., Zhang, Z., Kuruvilla, J., Camp, L., Li, M., Xu, H., Norman, J. L., Cahan, J., Vassar, R., Chen, J. & Castellani, R. J. & 3 others, , 2025, (Accepted/In press) In: Nature Medicine. 278.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Advancements in APOE and dementia research: Highlights from the 2023 AAIC Advancements: APOE conference
Kloske, C. M., Belloy, M. E., Blue, E. E., Bowman, G. R., Carrillo, M. C., Chen, X., Chiba-Falek, O., Davis, A. A., Paolo, G. D., Garretti, F., Gate, D., Golden, L. R., Heinecke, J. W., Herz, J., Huang, Y., Iadecola, C., Johnson, L. A., Kanekiyo, T., Karch, C. M. & Khvorova, A. & 40 others, , Sep 2024, In: Alzheimer's and Dementia. 20, 9, p. 6590-6605 16 p.Research output: Contribution to journal › Review article › peer-review
Open Access7 Scopus citations
Datasets
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Anti-CD49d Ab treatment ameliorates age-associated inflammatory response and mitigates CD8+ T-cell cytotoxicity after traumatic brain injury
Cui, W. (Creator), Gate, D. (Creator), Schwulst, S. J. (Creator), Weiss, C. (Creator), Islam, M. B. A. R. (Creator), Chen, Z. (Creator), Wang, Y. (Creator), Ramakrishnan, A. (Creator), Davis, B. T. (Creator), Ford, K. P. (Creator), Wan, H. (Creator) & Han, H. (Creator), figshare, 2024
DOI: 10.6084/m9.figshare.c.7501608.v1, https://springernature.figshare.com/collections/Anti-CD49d_Ab_treatment_ameliorates_age-associated_inflammatory_response_and_mitigates_CD8_T-cell_cytotoxicity_after_traumatic_brain_injury/7501608/1
Dataset