Grants per year
Personal profile
Research Interests
Dr. VanderWeele did his medical and research training at the University of Chicago, where he developed a research program characterizing the heterogeneity and evolution of the cancer genome. He moved to the National Cancer Institute in Bethesda, MD, where he continued to seek to improve the treatment of prostate cancer based on patients’ specific genetic changes. He returned to Chicago in 2018 to join the GU cancer team at Northwestern University, where he continues to translate discoveries made at the bench into improved therapies in the clinic.
Training Experience
| 2009 | Residency, University of Chicago |
| 2013 | Fellowship, University of Chicago |
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Medicine, MD, University of Chicago
… → 2007
Cancer Biology, PhD, University of Chicago
… → 2005
Research interests keywords
- Bladder Cancer
- Kidney Cancer / Urinary Tract Cancer
- Oncology
- Prostate Cancer
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Prot #NKT2152-202: A Phase 2 Trial to Evaluate the Safety and Efficacy of NKT2152 in Combination with Palbociclib (Doublet) and with Palbociclib and Sasanlimab (Triplet) in Subjects with Advanced or Metastatic Clear Cell Renal Cell Carcinoma
VanderWeele, D. J. (PD/PI)
Pharmaceutical Research Associates, Inc., NiKang Therapeutics, Inc.
11/1/23 → 11/1/26
Project: Research project
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Prot #CURLu177PSM0001: A Multi-Center, Open-Label, Randomized Phase 3 Trial Comparing the Safety and Efficacy of 177Lu-PSMA-I&T versus Hormone Therapy in Patients with Metastatic Castration-Resistant Prostate Cancer
VanderWeele, D. J. (PD/PI)
Cato Research Ltd., Curium US LLC
1/26/23 → 1/26/26
Project: Research project
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Prot #CAAA617C12301: PSMAddition: An International Prospective Open-label, Randomized, Phase III Study Comparing 177Lu-PSMA-617 in Combination with Standard of Care, Versus Standard of Care Alone, in Adult Male Patients with Metastatic Hormone Sensitive P
VanderWeele, D. J. (PD/PI)
Novartis Pharmaceuticals Corporation
2/9/22 → 11/21/25
Project: Research project
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Durable response to treatment of an atypical desmoplastic small round cell tumor with enfortumab-vedotin
Wang, J. S., Shapiro, J. C., Orlando, S., Al-Marayaty, R., Obeidin, F., VanderWeele, D., Charalambous, H., Pollack, S. M. & de Viveiros, P. H., Feb 2025, In: Journal of Cancer Research and Clinical Oncology. 151, 2, 73.Research output: Contribution to journal › Article › peer-review
Open Access -
Management Decisions for Metastatic Castration-resistant Prostate Cancer in 2024
VanderWeele, D. J. & Hussain, M., Jan 2025, In: European urology. 87, 1, p. 47-48 2 p.Research output: Contribution to journal › Editorial › peer-review
1 Scopus citations -
Phase I, First-in-Human Study of FOR46 (FG-3246), an Immune-Modulating Antibody-Drug Conjugate Targeting CD46, in Patients With Metastatic Castration-Resistant Prostate Cancer
Aggarwal, R. R., Vuky, J., Vanderweele, D., Rettig, M., Heath, E. I., Quigley, D., Huang, J., Chumber, A., Cheung, A., Foye, A., Leung, S., Abbey, J., Dorr, A., Nasoff, M., Hunter, J., Wang, S., Flavell, R. R., Fong, L., Liu, B. & Small, E. J., 2025, (Accepted/In press) In: Journal of Clinical Oncology.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Response to pembrolizumab in advanced prostate cancer with predictive biomarkers
Altomare, N. J., Li, Y., Neill, C., Hussain, M. & VanderWeele, D. J., Mar 1 2025, In: Oncologist. 30, 3, oyaf025.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Large Cell Neuroendocrine Prostate Cancer: Large Is Not Small
Serritella, A. V., Beltran, H., Lotan, T. L., VanderWeele, D. J., Karzai, F., Madan, R. A. & Hussain, M., Mar 2024, In: Oncologist. 29, 3, p. 185-189 5 p.Research output: Contribution to journal › Comment/debate › peer-review
Open Access2 Scopus citations