David James VanderWeele

  • 567 Citations
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Personal profile

Research Interests

Dr. VanderWeele did his medical and research training at the University of Chicago, where he developed a research program characterizing the heterogeneity and evolution of the cancer genome. He moved to the National Cancer Institute in Bethesda, MD, where he continued to seek to improve the treatment of prostate cancer based on patients’ specific genetic changes. He returned to Chicago in 2018 to join the GU cancer team at Northwestern University, where he continues to translate discoveries made at the bench into improved therapies in the clinic.

Training Experience

2009Residency, University of Chicago
2013Fellowship, University of Chicago

Education/Academic qualification

MD, University of Chicago

… → 2007

PhD, University of Chicago

… → 2005

Research interests

  • Bladder Cancer
  • Kidney Cancer / Urinary Tract Cancer
  • Oncology
  • Prostate Cancer

Fingerprint Dive into the research topics where David James VanderWeele is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 17 Similar Profiles
Prostatic Neoplasms Medicine & Life Sciences
Castration Medicine & Life Sciences
Mutation Medicine & Life Sciences
Circulating Neoplastic Cells Medicine & Life Sciences
Cells Chemical Compounds
Prostate Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Sirolimus Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output 2002 2019

  • 567 Citations
  • 16 Article
  • 2 Review article
  • 1 Comment/debate

mpMRI preoperative staging in men treated with antiandrogen and androgen deprivation therapy before robotic prostatectomy

Gold, S. A., VanderWeele, D. J., Harmon, S., Bloom, J. B., Karzai, F., Hale, G. R., Marhamati, S., Rayn, K. N., Mehralivand, S., Merino, M. J., Gulley, J. L., Bilusic, M., Madan, R. A., Choyke, P. L., Turkbey, B., Dahut, W. & Pinto, P. A., Jun 1 2019, In : Urologic Oncology: Seminars and Original Investigations. 37, 6, p. 352.e25-352.e30

Research output: Contribution to journalArticle

Androgen Antagonists
Magnetic Resonance Imaging
15 Citations (Scopus)

Activity of durvalumab plus olaparib in metastatic castration-resistant prostate cancer in men with and without DNA damage repair mutations 11 Medical and Health Sciences 1112 Oncology and Carcinogenesis

Karzai, F., VanderWeele, D. J., Madan, R. A., Owens, H., Cordes, L. M., Hankin, A., Couvillon, A., Nichols, E., Bilusic, M., Beshiri, M. L., Kelly, K., Krishnasamy, V., Lee, S., Lee, M. J., Yuno, A., Trepel, J. B., Merino, M. J., Dittamore, R., Marté, J., Donahue, R. N. & 7 others, Schlom, J., Killian, K. J., Meltzer, P. S., Steinberg, S. M., Gulley, J. L., Lee, J. M. & Dahut, W. L., Dec 4 2018, In : Journal for ImmunoTherapy of Cancer. 6, 1, 141.

Research output: Contribution to journalReview article

Open Access
DNA Repair
DNA Damage
Prostatic Neoplasms
4 Citations (Scopus)

Genomic Heterogeneity Within Individual Prostate Cancer Foci Impacts Predictive Biomarkers of Targeted Therapy

VanderWeele, D. J., Finney, R., Katayama, K., Gillard, M., Paner, G., Imoto, S., Yamaguchi, R., Wheeler, D., Lack, J., Cam, M., Pontier, A., Nguyen, Y. T. M., Maejima, K., Sasaki-Oku, A., Nakano, K., Tanaka, H., Vander Griend, D., Kubo, M., Ratain, M. J., Miyano, S. & 1 others, Nakagawa, H., Jan 1 2018, (Accepted/In press) In : European Urology Focus. 5, 3, p. 416-424 9 p.

Research output: Contribution to journalArticle

Prostatic Neoplasms
2 Citations (Scopus)

Integrative Genomic Analysis of Coincident Cancer Foci Implicates CTNNB1 and PTEN Alterations in Ductal Prostate Cancer

Gillard, M., Lack, J., Pontier, A., Gandla, D., Hatcher, D., Sowalsky, A. G., Rodriguez-Nieves, J., Vander Griend, D., Paner, G. & VanderWeele, D., Jan 1 2018, (Accepted/In press) In : European Urology Focus. 5, 3, p. 433-442 10 p.

Research output: Contribution to journalArticle

Phosphoric Monoester Hydrolases
Prostatic Neoplasms
Phosphatidylinositol 3-Kinases
16 Citations (Scopus)

Circulating tumor cells capture disease evolution in advanced prostate cancer

Lack, J., Gillard, M., Cam, M., Paner, G. P. & VanderWeele, D. J., Feb 23 2017, In : Journal of Translational Medicine. 15, 1, 44.

Research output: Contribution to journalArticle

Circulating Neoplastic Cells
Prostatic Neoplasms