Grants per year
Search results
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Active
Prot #NKT2152-101: A Phase 1/2, Open Label Dose-Escalation and Expansion Trial of NKT2152, an Orally Administered HIF-2α Inhibitor, to Investigate Safety, Pharmacokinetics, Pharmacodynamics and Clinical Activity in Patients with Advanced Clear Cell Renal
VanderWeele, D. J. (PD/PI)
Medpace Clinical Research LLC, NiKang Therapeutics, Inc.
5/23/25 → 5/23/28
Project: Research project
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Prot #NKT2152-202: A Phase 2 Trial to Evaluate the Safety and Efficacy of NKT2152 in Combination with Palbociclib (Doublet) and with Palbociclib and Sasanlimab (Triplet) in Subjects with Advanced or Metastatic Clear Cell Renal Cell Carcinoma
VanderWeele, D. J. (PD/PI)
Pharmaceutical Research Associates, Inc., NiKang Therapeutics, Inc.
11/1/23 → 11/1/26
Project: Research project
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Prot #CURLu177PSM0001: A Multi-Center, Open-Label, Randomized Phase 3 Trial Comparing the Safety and Efficacy of 177Lu-PSMA-I&T versus Hormone Therapy in Patients with Metastatic Castration-Resistant Prostate Cancer
VanderWeele, D. J. (PD/PI)
Cato Research Ltd., Curium US LLC
1/26/23 → 1/26/26
Project: Research project
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Prot #CAAA617C12301: PSMAddition: An International Prospective Open-label, Randomized, Phase III Study Comparing 177Lu-PSMA-617 in Combination with Standard of Care, Versus Standard of Care Alone, in Adult Male Patients with Metastatic Hormone Sensitive P
VanderWeele, D. J. (PD/PI)
Novartis Pharmaceuticals Corporation
2/9/22 → 11/21/25
Project: Research project
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SPORE in Prostate Cancer
Abdulkadir, S. A. (PD/PI), Abdulkadir, S. A. (PD/PI), Hussain, M. (Co-PD/PI), Hussain, M. (Co-PD/PI), Catalona, W. J. (Co-Investigator), Catalona, W. J. (Co-Investigator), Chakravarti, D. (Co-Investigator), Chakravarti, D. (Co-Investigator), Cooper, L. A. D. (Co-Investigator), Kim, K.-Y. A. (Co-Investigator), Kim, K.-Y. A. (Co-Investigator), Kim, K.-Y. A. (Co-Investigator), Morgans, A. K. (Co-Investigator), Morgans, A. K. (Co-Investigator), Murphy, A. B. (Co-Investigator), Murphy, A. B. (Co-Investigator), Ross, A. E. (Co-Investigator), Schiltz, G. E. (Co-Investigator), Schiltz, G. E. (Co-Investigator), VanderWeele, D. J. (Co-Investigator), Wei, J.-J. (Co-Investigator), Wei, J.-J. (Co-Investigator), Yang, R. (Co-Investigator), Yang, R. (Co-Investigator), Yu, J. (Co-Investigator), Yu, J. (Co-Investigator), Kocherginsky, M. (Other), Kocherginsky, M. (Other), Leikin, R. G. (Other), Leikin, R. G. (Other), Sosman, J. A. (Other), Sosman, J. A. (Other), Wu, J. D. (Other), Wu, J. D. (Other), Yang, X. J. (Other), Yang, X. J. (Other), Yang, R. (Other), Zhao, C. (Other) & Zhao, C. (Other)
9/1/21 → 7/31/26
Project: Research project
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North American Star Consortium
Mahalingam, D. (PD/PI), Mahalingam, D. (PD/PI), Sosman, J. A. (PD/PI), Sosman, J. A. (Co-PD/PI), Sosman, J. A. (Co-PD/PI), Kumthekar, P. U. (Co-Investigator), Kumthekar, P. U. (Co-Investigator), VanderWeele, D. J. (Co-Investigator) & VanderWeele, D. J. (Co-Investigator)
University Health Network (Toronto), National Cancer Institute
3/1/20 → 2/28/26
Project: Research project
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Prot #PCCTC #: c17-191: CASCARA: Castration Sensitive Carboplatin, Cabazitaxel and Abiraterone, A Phase II Study of Carboplatin, Cabazitaxel and Abiraterone in Metastatic Castration Sensitive Prostate Cancer with and without DNA Repair Mutations
VanderWeele, D. J. (PD/PI)
Prostate Cancer Clinical Trials Consortium, LLC, Genzyme Corporation
2/28/20 → 2/28/26
Project: Research project
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Prot #D933RC00001: A Phase III, Randomized, Open-Label, Multi-Center, Global Study to Determine the Efficacy and Safety of Durvalumab in Combination with Gemcitabine+Cisplatin for Neoadjuvant Treatment Followed by Durvalumab Alone for Adjuvant Treatment i
VanderWeele, D. J. (PD/PI)
AstraZeneca Pharmaceuticals LP
11/20/19 → 11/20/25
Project: Research project
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Prot #D933SC00001: A Phase III, Randomized, Open-Label, Controlled, Multi-Center, Global Study of First-Line Durvalumab in Combination with Standard of Care Chemotherapy and Durvalumab in Combination with Tremelimumab and Standard of Care Chemotherapy Ver
VanderWeele, D. J. (PD/PI)
AstraZeneca Pharmaceuticals LP
7/22/19 → 7/22/25
Project: Research project
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Finished
Year 1 award
Serritella, A. V. (PD/PI) & VanderWeele, D. J. (Other)
7/1/23 → 6/30/24
Project: Research project
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Prot #7051-ONC-101: A Phase 1 Study of FT-7051 in Men with Metastatic Castration-Resistant Prostate Cancer
VanderWeele, D. J. (PD/PI)
Novella Clinical, LLC, FORMA Therapeutics, Inc.
4/6/21 → 4/6/24
Project: Research project
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Prot #ARC-6: A Phase 1b/2, Open-Label, Randomized Platform Study Evaluating the Efficacy and Safety of AB928-Based Treatment Combinations in Patients with Metastatic Castrate Resistant Prostate Cancer
VanderWeele, D. J. (PD/PI)
Novella Clinical, LLC, Arcus Biosciences, Inc
11/12/20 → 11/12/24
Project: Research project
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Prot #B9991040: A Phase 1b/2 Study to Evaluate Safety and Clinical Activity of Avelumab in Combination with Bempegaldesleukin (NKTR-214) with or without Talazoparib or Enzalutamide in Participants with Locally Advanced or Metastatic Solid Tumors
VanderWeele, D. J. (PD/PI)
2/10/20 → 2/10/23
Project: Research project