Grants per year
Personal profile
Research Interests
Multiphoton Microscopy of living cells and tissues. See NINDS P-30 grant.
Education/Academic qualification
PhD, University of Texas
… → 2004
Research interests keywords
- Biophysics
- Microscopy
- Physiology
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- 1 Similar Profiles
Collaborations and top research areas from the last five years
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Dopaminergic and Muscarinic Signaling in the Striatum
Surmeier Jr, D. J. (PD/PI), Cui, Q. (Other), Shen, W. (Other) & Wokosin, D. L. (Other)
National Institute of Neurological Disorders and Stroke
7/1/24 → 6/30/27
Project: Research project
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Resilience, Dysregulation, and Rescue of Basal Ganglia Indirect Pathway Function in Progressive Parkinsonism
Bevan, M. D. (PD/PI), Bevan, M. D. (PD/PI), Atherton, J. F. (Co-Investigator), Atherton, J. F. (Co-Investigator), Solla, S. A. (Co-Investigator), Wokosin, D. L. (Co-Investigator) & Wokosin, D. L. (Co-Investigator)
National Institute of Neurological Disorders and Stroke
3/1/22 → 4/30/27
Project: Research project
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Neural Adaptations in Huntington's Disease
Surmeier Jr, D. J. (PD/PI), Surmeier Jr, D. J. (PD/PI), Bevan, M. D. (Co-Investigator), Bevan, M. D. (Co-Investigator), Atherton, J. F. (Other), Atherton, J. F. (Other), Callahan, J. W. (Other), Callahan, J. W. (Other), Day, M. (Other), Day, M. (Other), Kondapalli, J. (Other), Kondapalli, J. (Other), Pancani, T. (Other), Pancani, T. (Other), Wokosin, D. L. (Other), Wokosin, D. L. (Other), Xie, Z. (Other) & Xie, Z. (Other)
4/1/18 → 3/31/25
Project: Research project
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Molecular and Cellular Mechanisms of Parkinson's Disease
Surmeier Jr, D. J. (PD/PI), Surmeier Jr, D. J. (PD/PI), Guzman-Lucero, J. N. (Other), Guzman-Lucero, J. N. (Other), Ilijic, E. (Other), Ilijic, E. (Other), Shen, W. (Other), Shen, W. (Other), Wokosin, D. L. (Other), Wokosin, D. L. (Other), Xie, Z. (Other), Xie, Z. (Other) & Zampese, E. (Other)
11/1/21 → 10/31/24
Project: Research project
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Dopaminergic and Muscarinic Signaling in the Striatum
Surmeier Jr, D. J. (PD/PI), Surmeier Jr, D. J. (PD/PI), Shen, W. (Other), Wokosin, D. L. (Other) & Zhai, S. (Other)
National Institute of Neurological Disorders and Stroke
7/1/20 → 6/30/24
Project: Research project
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Ca2+-dependent phosphodiesterase 1 regulates the plasticity of striatal spiny projection neuron glutamatergic synapses
Zhai, S., Otsuka, S., Xu, J., Clarke, V. R. J., Tkatch, T., Wokosin, D., Xie, Z., Tanimura, A., Agarwal, H. K., Ellis-Davies, G. C. R., Contractor, A. & Surmeier, D. J., Aug 27 2024, In: Cell reports. 43, 8, 114540.Research output: Contribution to journal › Article › peer-review
Open Access -
GABAergic regulation of striatal spiny projection neurons depends upon their activity state
Day, M., Belal, M., Surmeier, W. C., Melendez, A., Wokosin, D. L., Tkatch, T., Clarke, V. R. J. & Surmeier Jr, D. J., Jan 2024, In: PLoS biology. 22, 1Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Cholinergic deficits selectively boost cortical intratelencephalic control of striatum in male Huntington’s disease model mice
Pancani, T., Day, M., Tkatch, T., Wokosin, D. L., González-Rodríguez, P., Kondapalli, J., Xie, Z., Chen, Y., Beaumont, V. & Surmeier Jr, D. J., Dec 2023, In: Nature communications. 14, 1, 1398.Research output: Contribution to journal › Article › peer-review
Open Access8 Scopus citations -
Acute and protracted abstinence from methamphetamine bidirectionally changes intrinsic excitability of indirect pathway spiny projection neurons in the dorsomedial striatum
Choi, S., Du, Y., Wokosin, D. L. & Graves, S. M., Dec 2022, In: Scientific reports. 12, 1, 12116.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Author Correction: Disruption of mitochondrial complex I induces progressive parkinsonism (Nature, (2021), 599, 7886, (650-656), 10.1038/s41586-021-04059-0)
González-Rodríguez, P., Zampese, E., Stout, K. A., Guzman, J. N., Ilijic, E., Yang, B., Tkatch, T., Stavarache, M. A., Wokosin, D. L., Gao, L., Kaplitt, M. G., López-Barneo, J., Schumacker, P. T. & Surmeier, D. J., Mar 3 2022, In: Nature. 603, 7899, p. E1Research output: Contribution to journal › Comment/debate › peer-review
Open Access2 Scopus citations
Datasets
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Source data for "Ca2+ channels couple spiking to mitochondrial metabolism in substantia nigra dopaminergic neurons"
Zampese, E. (Contributor), Wokosin, D. L. (Contributor), Guzman, J. N. (Contributor), Tkatch, T. (Contributor), Kondapalli, J. (Contributor), Surmeier, W. C. (Contributor), D'Alessandro, K. B. (Contributor), De Stefani, D. (Contributor), Rizzuto, R. (Contributor), Iino, M. (Contributor), Molkentin, J. D. (Contributor), Chandel, N. S. (Contributor), Schumacker, P. T. (Contributor) & Surmeier, D. J. (Contributor), ZENODO, Aug 8 2022
DOI: 10.5281/zenodo.6949450, https://zenodo.org/records/6949450
Dataset
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The role of intra-articular neuronal CCR2 receptors in knee joint pain associated with experimental osteoarthritis in mice
Ishihara, S. (Creator), Obeidat, A. M. (Creator), Wokosin, D. L. (Creator), Ren, D. (Contributor), Miller, R. J. (Creator), Malfait, A.-M. (Creator) & Miller, R. E. (Creator), figshare, 2021
DOI: 10.6084/m9.figshare.c.5368555, https://springernature.figshare.com/collections/The_role_of_intra-articular_neuronal_CCR2_receptors_in_knee_joint_pain_associated_with_experimental_osteoarthritis_in_mice/5368555
Dataset
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α-Synuclein pathology disrupts mitochondrial function in dopaminergic and cholinergic neurons at-risk in Parkinson’s disease
Chandel, N. S. (Creator), Grotmann, C. A. (Creator), Wokosin, D. L. (Creator), Xie, Z. (Creator), Nasiri, E. (Creator), Öertel, W. H. (Contributor) & Dawson, V. L. (Creator), figshare, 2024
DOI: 10.6084/m9.figshare.c.7485396.v1, https://springernature.figshare.com/collections/_-Synuclein_pathology_disrupts_mitochondrial_function_in_dopaminergic_and_cholinergic_neurons_at-risk_in_Parkinson_s_disease/7485396/1
Dataset