Grants per year
Personal profile
Research Interests
Multiphoton Microscopy of living cells and tissues. See NINDS P-30 grant.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
PhD, University of Texas
… → 2004
Research interests keywords
- Biophysics
- Microscopy
- Physiology
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Dive into the research topics where David L Wokosin is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Distributed circuit dysfunction underlying motor and sleep deficits in a progressive mouse model of Parkinson’s disease (Renewal)
Surmeier Jr, D. J. (PD/PI), Clarke, V. (Other), Ilijic, E. (Other), Wokosin, D. L. (Other) & Zhai, S. (Other)
Michael J. Fox Foundation for Parkinson's Research
11/1/24 → 10/31/26
Project: Research project
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Bevan Subproject
Bevan, M. D. (Co-Investigator) & Wokosin, D. L. (Other)
Michael J. Fox Foundation for Parkinson's Research
11/1/24 → 10/31/26
Project: Research project
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Molecular and Cellular Mechanisms of Parkinson's Disease
Surmeier Jr, D. J. (PD/PI), Guzman-Lucero, J. N. (Other), Ilijic, E. (Other), Shen, W. (Other), Tkatch, T. (Other), Wokosin, D. L. (Other) & Zampese, E. (Other)
10/1/24 → 9/30/27
Project: Research project
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Dopaminergic and Muscarinic Signaling in the Striatum
Surmeier Jr, D. J. (PD/PI), Cui, Q. (Other), Shen, W. (Other) & Wokosin, D. L. (Other)
National Institute of Neurological Disorders and Stroke
7/1/24 → 6/30/27
Project: Research project
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Resilience, Dysregulation, and Rescue of Basal Ganglia Indirect Pathway Function in Progressive Parkinsonism
Bevan, M. D. (PD/PI), Bevan, M. D. (PD/PI), Atherton, J. F. (Co-Investigator), Atherton, J. F. (Co-Investigator), Atherton, J. F. (Co-Investigator), Solla, S. A. (Co-Investigator), Wokosin, D. L. (Co-Investigator) & Wokosin, D. L. (Co-Investigator)
National Institute of Neurological Disorders and Stroke
3/1/22 → 4/30/27
Project: Research project
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Ca2+-dependent phosphodiesterase 1 regulates the plasticity of striatal spiny projection neuron glutamatergic synapses
Zhai, S., Otsuka, S., Xu, J., Clarke, V. R. J., Tkatch, T., Wokosin, D., Xie, Z., Tanimura, A., Agarwal, H. K., Ellis-Davies, G. C. R., Contractor, A. & Surmeier, D. J., Aug 27 2024, In: Cell reports. 43, 8, 114540.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
GABAergic regulation of striatal spiny projection neurons depends upon their activity state
Day, M., Belal, M., Surmeier, W. C., Melendez, A., Wokosin, D., Tkatch, T., Clarke, V. R. J. & Surmeier, D. J., Jan 2024, In: PLoS biology. 22, 1Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
α-Synuclein pathology disrupts mitochondrial function in dopaminergic and cholinergic neurons at-risk in Parkinson’s disease
Geibl, F. F., Henrich, M. T., Xie, Z., Zampese, E., Ueda, J., Tkatch, T., Wokosin, D. L., Nasiri, E., Grotmann, C. A., Dawson, V. L., Dawson, T. M., Chandel, N. S., Oertel, W. H. & Surmeier, D. J., Dec 2024, In: Molecular neurodegeneration. 19, 1, 69.Research output: Contribution to journal › Article › peer-review
6 Scopus citations -
Cholinergic deficits selectively boost cortical intratelencephalic control of striatum in male Huntington’s disease model mice
Pancani, T., Day, M., Tkatch, T., Wokosin, D. L., González-Rodríguez, P., Kondapalli, J., Xie, Z., Chen, Y., Beaumont, V. & Surmeier Jr, D. J., Dec 2023, In: Nature communications. 14, 1, 1398.Research output: Contribution to journal › Article › peer-review
Open Access11 Scopus citations -
Acute and protracted abstinence from methamphetamine bidirectionally changes intrinsic excitability of indirect pathway spiny projection neurons in the dorsomedial striatum
Choi, S., Du, Y., Wokosin, D. L. & Graves, S. M., Dec 2022, In: Scientific reports. 12, 1, 12116.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations
Datasets
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Source data for "Ca2+ channels couple spiking to mitochondrial metabolism in substantia nigra dopaminergic neurons"
Zampese, E. (Contributor), Wokosin, D. L. (Contributor), Guzman, J. N. (Contributor), Tkatch, T. (Contributor), Kondapalli, J. (Contributor), Surmeier, W. C. (Contributor), D'Alessandro, K. B. (Contributor), De Stefani, D. (Contributor), Rizzuto, R. (Contributor), Iino, M. (Contributor), Molkentin, J. D. (Contributor), Chandel, N. S. (Contributor), Schumacker, P. T. (Contributor) & Surmeier, D. J. (Contributor), ZENODO, Aug 8 2022
DOI: 10.5281/zenodo.6949450, https://zenodo.org/records/6949450
Dataset
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α-Synuclein pathology disrupts mitochondrial function in dopaminergic and cholinergic neurons at-risk in Parkinson’s disease
Chandel, N. S. (Creator), Grotmann, C. A. (Creator), Wokosin, D. L. (Creator), Xie, Z. (Creator), Nasiri, E. (Creator), Öertel, W. H. (Contributor) & Dawson, V. L. (Creator), figshare, 2024
DOI: 10.6084/m9.figshare.c.7485396.v1, https://springernature.figshare.com/collections/_-Synuclein_pathology_disrupts_mitochondrial_function_in_dopaminergic_and_cholinergic_neurons_at-risk_in_Parkinson_s_disease/7485396/1
Dataset
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The role of intra-articular neuronal CCR2 receptors in knee joint pain associated with experimental osteoarthritis in mice
Ishihara, S. (Creator), Obeidat, A. M. (Creator), Wokosin, D. L. (Creator), Ren, D. (Contributor), Miller, R. J. (Creator), Malfait, A.-M. (Creator) & Miller, R. E. (Creator), figshare, 2021
DOI: 10.6084/m9.figshare.c.5368555, https://springernature.figshare.com/collections/The_role_of_intra-articular_neuronal_CCR2_receptors_in_knee_joint_pain_associated_with_experimental_osteoarthritis_in_mice/5368555
Dataset