David L Wokosin

  • 2689 Citations
19962021
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Personal profile

Research Interests

Multiphoton Microscopy of living cells and tissues. See NINDS P-30 grant.

Education/Academic qualification

PhD, University of Texas

… → 2004

Keywords

  • Biophysics
  • Microscopy
  • Physiology

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Neurons Medicine & Life Sciences
Photons Medicine & Life Sciences
Imaging techniques Engineering & Materials Science
Microscopic examination Engineering & Materials Science
Lasers Engineering & Materials Science
microscopy Physics & Astronomy
Subthalamic Nucleus Medicine & Life Sciences
Corpus Striatum Medicine & Life Sciences

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Grants 2005 2021

Parkinson Disease
Levodopa
Dopaminergic Neurons
Dyskinesias
Substantia Nigra
Levodopa
Parkinson Disease
Dyskinesias
Dopaminergic Neurons
Muscarinic M4 Receptors

Research Output 1996 2019

1 Citation (Scopus)

Cholinergic Interneurons Amplify Thalamostriatal Excitation of Striatal Indirect Pathway Neurons in Parkinson's Disease Models

Tanimura, A., Du, Y., Kondapalli, J., Wokosin, D. L. & Surmeier Jr, D. J., Feb 6 2019, In : Neuron. 101, 3, p. 444-458.e6

Research output: Contribution to journalArticle

Intralaminar Thalamic Nuclei
Corpus Striatum
Interneurons
Cholinergic Agents
Parkinson Disease

Probing nicotinic acetylcholine receptor function in mouse brain slices via laser flash photolysis of photoactivatable nicotine

Arvin, M. C., Wokosin, D. L., Banala, S., Lavis, L. D. & Drenan, R. M., Jan 1 2019, In : Journal of Visualized Experiments. 2019, 143, e58873.

Research output: Contribution to journalArticle

Nicotine
Photolysis
Nicotinic Receptors
Brain
Lasers
1 Citation (Scopus)

Nicotinic Cholinergic Receptors in VTA Glutamate Neurons Modulate Excitatory Transmission

Yan, Y., Peng, C., Arvin, M. C., Jin, X. T., Kim, V. J., Ramsey, M. D., Wang, Y., Banala, S., Wokosin, D. L., McIntosh, J. M., Lavis, L. D. & Drenan, R. M., May 22 2018, In : Cell reports. 23, 8, p. 2236-2244 9 p.

Research output: Contribution to journalArticle

Ventral Tegmental Area
Nicotinic Receptors
Cholinergic Receptors
Neurons
Glutamic Acid
5 Citations (Scopus)

Photoactivatable drugs for nicotinic optopharmacology

Banala, S., Arvin, M. C., Bannon, N. M., Jin, X. T., Macklin, J. J., Wang, Y., Peng, C., Zhao, G., Marshall, J. J., Gee, K. R., Wokosin, D. L., Kim, V. J., McIntosh, J. M., Contractor, A., Lester, H. A., Kozorovitskiy, Y., Drenan, R. M. & Lavis, L. D., Apr 27 2018, In : Nature Methods. 15, 5, p. 347-350 4 p.

Research output: Contribution to journalArticle

Photons
Nicotinic Receptors
Neurosciences
Nicotine
Ammonium Compounds
9 Citations (Scopus)

Systemic isradipine treatment diminishes calcium-dependent mitochondrial oxidant stress

Guzman-Lucero, J. N., Ilijic, E., Yang, B., Sanchez-Padilla, J., Wokosin, D. L., Galtieri, D., Kondapalli, J., Schumacker, P. T. & Surmeier Jr, D. J., Jun 1 2018, In : Journal of Clinical Investigation. 128, 6, p. 2266-2280 15 p.

Research output: Contribution to journalArticle

Isradipine
Dopaminergic Neurons
Oxidants
Calcium
Mitochondrial Degradation