David O Walterhouse

  • 2543 Citations
1984 …2020

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Article
2020

Impact of local control and surgical lymph node evaluation in localized paratesticular rhabdomyosarcoma: A report from the Children's Oncology Group Soft Tissue Sarcoma Committee

Routh, J. C., Dasgupta, R., Chi, Y. Y., Shnorhavorian, M., Tian, J., Walterhouse, D. O., Breneman, J., Wolden, S. L., Arndt, C. A., Hawkins, D. S. & Rodeberg, D. A., 2020, (Accepted/In press) In : International Journal of Cancer.

Research output: Contribution to journalArticle

Survival of Patients With Non-Rhabdomyosarcoma Soft Tissue Sarcomas of the Head and Neck

Rastatter, J. C., Sinard, R. N., Dilger, A., Reichek, J., Walterhouse, D. O. & Patel, U., 2020, (Accepted/In press) In : Laryngoscope.

Research output: Contribution to journalArticle

Up-regulation of GLI1 in vincristine-resistant rhabdomyosarcoma and Ewing sarcoma

Yoon, J. W., Lamm, M., Chandler, C., Iannaccone, P. M. & Walterhouse, D. O., Jun 3 2020, In : BMC cancer. 20, 1, 511.

Research output: Contribution to journalArticle

Open Access
2019

Cardiac-Sparing Whole Lung IMRT in Patients With Pediatric Tumors and Lung Metastasis: Final Report of a Prospective Multicenter Clinical Trial

Kalapurakal, J. A., Gopalakrishnan, M., Walterhouse, D. O., Rigsby, C. K., Rademaker, A. W., Helenowski, I., Kessel, S., Morano, K., Laurie, F., Ulin, K., Esiashvili, N., Katzenstein, H., Marcus, K., Followill, D. S., Wolden, S. L., Mahajan, A. & Fitzgerald, T. J., Jan 1 2019, In : International Journal of Radiation Oncology Biology Physics. 103, 1, p. 28-37 10 p.

Research output: Contribution to journalArticle

3 Scopus citations

Regulation of GLI1 by cis DNA elements and epigenetic marks

Taylor, R., Long, J., Yoon, J. W., Childs, R., Sylvestersen, K. B., Nielsen, M. L., Leong, K. F., Iannaccone, S., Walterhouse, D. O., Robbins, D. J. & Iannaccone, P., Jul 2019, In : DNA Repair. 79, p. 10-21 12 p.

Research output: Contribution to journalArticle

Open Access
6 Scopus citations

Risk-based treatment for patients with first relapse or progression of rhabdomyosarcoma: A report from the Children's Oncology Group

Mascarenhas, L., Lyden, E. R., Breitfeld, P. P., Walterhouse, D. O., Donaldson, S. S., Rodeberg, D. A., Parham, D. M., Anderson, J. R., Meyer, W. H. & Hawkins, D. S., Aug 1 2019, In : Cancer. 125, 15, p. 2602-2609 8 p.

Research output: Contribution to journalArticle

4 Scopus citations

Treatment Approach and Outcomes in Infants With Localized Rhabdomyosarcoma: A Report From the Soft Tissue Sarcoma Committee of the Children's Oncology Group

Bradley, J. A., Kayton, M. L., Chi, Y. Y., Hawkins, D. S., Tian, J., Breneman, J., Wolden, S. L., Walterhouse, D., Rodeberg, D. A. & Donaldson, S. S., Jan 1 2019, In : International Journal of Radiation Oncology Biology Physics. 103, 1, p. 19-27 9 p.

Research output: Contribution to journalArticle

6 Scopus citations
2018

Demographic and treatment variables influencing outcome for localized paratesticular rhabdomyosarcoma: Results from a pooled analysis of North American and European cooperative groups

Walterhouse, D. O., Barkauskas, D. A., Hall, D., Ferrari, A., De Salvo, G. L., Koscielniak, E., Stevens, M. C. G., Martelli, H., Seitz, G., Rodeberg, D. A., Shnorhavorian, M., Dasgupta, R., Breneman, J. C., Anderson, J. R., Bergeron, C., Bisogno, G., Meyer, W. H., Hawkins, D. S. & Minard-Colin, V., Dec 10 2018, In : Journal of Clinical Oncology. 36, 35, p. 3466-3476 11 p.

Research output: Contribution to journalArticle

7 Scopus citations

Localized vaginal/uterine rhabdomyosarcoma—results of a pooled analysis from four international cooperative groups

International Society of Pediatric Oncology Sarcoma Committee, the Children's Oncology Group, the Italian Cooperative Soft Tissue Sarcoma Group, and the European pediatric Soft tissue sarcoma Study Group, Sep 2018, In : Pediatric Blood and Cancer. 65, 9, e27096.

Research output: Contribution to journalArticle

4 Scopus citations

Prolonged response to sorafenib in a patient with refractory metastatic osteosarcoma and a somatic PDGFRA D846V mutation

Armstrong, A. E., Walterhouse, D. O., Leavey, P. J., Reichek, J. & Walz, A. L., Jan 1 2018, (Accepted/In press) In : Pediatric Blood and Cancer. 66, 1, e27493.

Research output: Contribution to journalArticle

2 Scopus citations
2017

45 Gy is not sufficient radiotherapy dose for Group III orbital embryonal rhabdomyosarcoma after less than complete response to 12 weeks of ARST0331 chemotherapy: A report from the Soft Tissue Sarcoma Committee of the Children's Oncology Group

Ermoian, R. P., Breneman, J., Walterhouse, D. O., Chi, Y. Y., Meza, J., Anderson, J., Hawkins, D. S., Hayes-Jordan, A. A., Parham, D. M., Yock, T. I., Donaldson, S. S. & Wolden, S. L., Sep 2017, In : Pediatric Blood and Cancer. 64, 9, e26540.

Research output: Contribution to journalArticle

12 Scopus citations

Reduction of cyclophosphamide dose for patients with subset 2 low-risk rhabdomyosarcoma is associated with an increased risk of recurrence: A report from the Soft Tissue Sarcoma Committee of the Children's Oncology Group

Walterhouse, D. O., Pappo, A. S., Meza, J. L., Breneman, J. C., Hayes-Jordan, A., Parham, D. M., Cripe, T. P., Anderson, J. R., Meyer, W. H. & Hawkins, D. S., Jun 15 2017, In : Cancer. 123, 12, p. 2368-2375 8 p.

Research output: Contribution to journalArticle

31 Scopus citations

Sonic hedgehog regulation of Foxf2 promotes cranial neural crest mesenchyme proliferation and is disrupted in cleft lip morphogenesis

Everson, J. L., Fink, D. M., Yoon, J. W., Leslie, E. J., Kietzman, H. W., Ansen-Wilson, L. J., Chung, H. M., Walterhouse, D. O., Marazita, M. L. & Lipinski, R. J., 2017, In : Development (Cambridge). 144, 11, p. 2082-2091 10 p.

Research output: Contribution to journalArticle

21 Scopus citations
2016

Histology, Fusion Status, and Outcome in Alveolar Rhabdomyosarcoma With Low-Risk Clinical Features: A Report From the Children's Oncology Group

Arnold, M. A., Anderson, J. R., Gastier-Foster, J. M., Barr, F. G., Skapek, S. X., Hawkins, D. S., Raney, R. B., Parham, D. M., Teot, L. A., Rudzinski, E. R. & Walterhouse, D. O., Apr 1 2016, In : Pediatric blood & cancer. 63, 4, p. 634-639 6 p.

Research output: Contribution to journalArticle

25 Scopus citations
2 Scopus citations
12 Scopus citations
2015

P53 modulates the activity of the GLI1 oncogene through interactions with the shared coactivator TAF9

Yoon, J. W., Lamm, M. L. G., Iannaccone, S., Higashiyama, N., Leong, K. F., Iannaccone, P. M. & Walterhouse, D. O., Oct 1 2015, In : DNA Repair. 34, p. 9-17 9 p.

Research output: Contribution to journalArticle

12 Scopus citations

Treatment of neuroblastoma in congenital central hypoventilation syndrome with a PHOX2B polyalanine repeat expansion mutation: New twist on a neurocristopathy syndrome

Armstrong, A. E., Weese-Mayer, D. E., Mian, A., Maris, J. M., Batra, V., Gosiengfiao, Y., Reichek, J., Madonna, M. B., Bush, J. W., Shore, R. M. & Walterhouse, D. O., Nov 1 2015, In : Pediatric Blood and Cancer. 62, 11, p. 2007-2010 4 p.

Research output: Contribution to journalArticle

5 Scopus citations
2014

Cost minimization analysis of two treatment regimens for low-risk rhabdomyosarcoma in children: A report from the Children's Oncology Group

Russell, H., Swint, J. M., Lal, L., Meza, J., Walterhouse, D., Hawkins, D. S. & Okcu, M. F., Jun 2014, In : Pediatric Blood and Cancer. 61, 6, p. 970-976 7 p.

Research output: Contribution to journalArticle

13 Scopus citations

Irinotecan and temozolomide for treatment of neuroblastoma in a patient with renal failure on hemodialysis

Armstrong, A. E., Dargart, J., Reichek, J., Walterhouse, D. O., Matossian, D., Cohn, R. A. & Gosiengfiao, Y., May 2014, In : Pediatric Blood and Cancer. 61, 5, p. 949-950 2 p.

Research output: Contribution to journalArticle

4 Scopus citations

Shorter-duration therapy using vincristine, dactinomycin, and lower-dose cyclophosphamide with or without radiotherapy for patients with newly diagnosed low-risk rhabdomyosarcoma: A report from the soft tissue sarcoma committee of the Children's Oncology Group

Walterhouse, D. O., Pappo, A. S., Meza, J. L., Breneman, J. C., Hayes-Jordan, A. A., Parham, D. M., Cripe, T. P., Anderson, J. R., Meyer, W. H. & Hawkins, D. S., Nov 1 2014, In : Journal of Clinical Oncology. 32, 31, p. 3547-3552 6 p.

Research output: Contribution to journalArticle

55 Scopus citations
2013

Histologic and clinical characteristics can guide staging evaluations for children and adolescents with rhabdomyosarcoma: A report from the children's oncology group soft tissue sarcoma committee

Weiss, A. R., Lyden, E. R., Anderson, J. R., Hawkins, D. S., Spunt, S. L., Walterhouse, D. O., Wolden, S. L., Parham, D. M., Rodeberg, D. A., Kao, S. C. & Womer, R. B., Sep 10 2013, In : Journal of Clinical Oncology. 31, 26, p. 3226-3232 7 p.

Research output: Contribution to journalArticle

40 Scopus citations

Noncanonical regulation of the hedgehog mediator GLI1 by c-MYC in Burkitt lymphoma

Yoon, J. W., Gallant, M., Lamm, M. L. G., Iannaccone, S., Vieux, K. F., Proytcheva, M., Hyjek, E., Iannaccone, P. M. & Walterhouse, D. O., Jun 1 2013, In : Molecular Cancer Research. 11, 6, p. 604-615 12 p.

Research output: Contribution to journalArticle

27 Scopus citations
2012
10 Scopus citations

Local control with reduced-dose radiotherapy for low-risk rhabdomyosarcoma: A report from the Children'S Oncology Group D9602 study

Breneman, J., Meza, J., Donaldson, S. S., Raney, R. B., Wolden, S., Michalski, J., Laurie, F., Rodeberg, D. A., Meyer, W., Walterhouse, D. & Hawkins, D. S., Jun 1 2012, In : International Journal of Radiation Oncology Biology Physics. 83, 2, p. 720-726 7 p.

Research output: Contribution to journalArticle

50 Scopus citations
13 Scopus citations

Three dimensional visualization and fractal analysis of mosaic patches in rat chimeras: Cell assortment in liver, adrenal cortex and cornea

Iannaccone, S., Zhou, Y., Walterhouse, D., Taborn, G., Landini, G. & Iannaccone, P., Feb 7 2012, In : PloS one. 7, 2, e31609.

Research output: Contribution to journalArticle

13 Scopus citations
2011

Local control and outcome in children with localized vaginal rhabdomyosarcoma: A report from the Soft Tissue Sarcoma committee of the Children's Oncology Group

Walterhouse, D. O., Meza, J. L., Breneman, J. C., Donaldson, S. S., Hayes-Jordan, A., Pappo, A. S., Arndt, C., Raney, R. B., Meyer, W. H. & Hawkins, D. S., Jul 15 2011, In : Pediatric Blood and Cancer. 57, 1, p. 76-83 8 p.

Research output: Contribution to journalArticle

44 Scopus citations
98 Scopus citations
2010

Randomized phase II window trial of two schedules of irinotecan with vincristine in patients with first relapse or progression of rhabdomyosarcoma: A report from the Children's Oncology Group

Mascarenhas, L., Lyden, E. R., Breitfeld, P. P., Walterhouse, D. O., Donaldson, S. S., Paidas, C. N., Parham, D. M., Anderson, J. R., Meyer, W. H. & Hawkins, D. S., Oct 20 2010, In : Journal of Clinical Oncology. 28, 30, p. 4658-4663 6 p.

Research output: Contribution to journalArticle

48 Scopus citations
2009

Defining a role for Sonic hedgehog pathway activation in desmoplastic medulloblastoma by identifying GLI1 target genes

Yoon, J. W., Gilbertson, R., Iannaccone, S., Iannaccone, P. & Walterhouse, D., Jan 1 2009, In : International Journal of Cancer. 124, 1, p. 109-119 11 p.

Research output: Contribution to journalArticle

55 Scopus citations

GLI1 genotypes do not predict basal cell carcinoma risk: A case control study

Watson, A., Kent, P., Alam, M., Paller, A. S., Umbach, D. M., Yoon, J. W., Iannaccone, P. M. & Walterhouse, D. O., Nov 30 2009, In : Molecular Cancer. 8, 113.

Research output: Contribution to journalArticle

3 Scopus citations

Paracrine sonic hedgehog signalling by prostate cancer cells induces osteoblast differentiation

Zunich, S. M., Douglas, T., Valdovinos, M., Chang, T., Bushman, W., Walterhouse, D. O., Iannaccone, P. M. & Lamm, M. L. G., Mar 2 2009, In : Molecular Cancer. 8, 12.

Research output: Contribution to journalArticle

31 Scopus citations

Sonic Hedgehog-responsive genes in the fetal prostate

Yu, M., Gipp, J., Yoon, J. W., Iannaccone, P., Walterhouse, D. & Bushman, W., Feb 27 2009, In : Journal of Biological Chemistry. 284, 9, p. 5620-5629 10 p.

Research output: Contribution to journalArticle

36 Scopus citations
2008

Quantification of vincristine and its major metabolite in human plasma by high-performance liquid chromatography/tandem mass spectrometry

Dennison, J. B., Renbarger, J. L., Walterhouse, D. O., Jones, D. R. & Hall, S. D., Jun 1 2008, In : Therapeutic drug monitoring. 30, 3, p. 357-364 8 p.

Research output: Contribution to journalArticle

25 Scopus citations
2007

Androgen and c-Kit receptors in desmoplastic small round cell tumors resistant to chemotherapy: Novel targets for therapy

Fine, R. L., Shah, S. S., Moulton, T. A., Yu, I. R., Fogelman, D. R., Richardson, M., Burris, H. A., Samuels, B. L., Assanasen, C., Gorroochurn, P., Hibshoosh, H., Orjuela, M., Garvin, J., Goldman, F. D., Dubovsky, D., Walterhouse, D. & Halligan, G., Mar 1 2007, In : Cancer Chemotherapy and Pharmacology. 59, 4, p. 429-437 9 p.

Research output: Contribution to journalArticle

22 Scopus citations

Distinguishing undifferentiated embryonal sarcoma of the liver from biliary tract rhabdomyosarcoma: A children's oncology group study

Nicol, K., Savell, V., Moore, J., Teot, L., Spunt, S. L., Qualman, S., Andrassy, R. J., Arndt, C. A. S., Baker, K. S., Barr, F. G., Bleyer, W. A., Breitfeld, P., Breneman, J. C., Bridge, J., Brown, K., Donaldson, S. S., Grier, H. E., Hawkins, D., Houghton, P. J., Link, M. & 18 others, Lobe, T. L., Maurer, H. M., Meyer, W. H., Michalski, J., Paidas, C. N., Pappo, A. S., Parham, D. M., Raney, R. B., Robison, L., Sandler, E., Skapek, S., Smith, L., Sorenson, P. H. B., Walterhouse, D., Wharam, M., Wiener, E. S., Wolden, S. & Womer, R., Mar 2007, In : Pediatric and Developmental Pathology. 10, 2, p. 89-97 9 p.

Research output: Contribution to journalArticle

39 Scopus citations
23 Scopus citations
2006

N-myc can substitute for insulin-like growth factor signaling in a mouse model of Sonic hedgehog-induced medulloblastoma

Browd, S. R., Kenney, A. M., Gottfried, O. N., Yoon, J. W., Walterhouse, D., Pedone, C. A. & Fults, D. W., Mar 1 2006, In : Cancer Research. 66, 5, p. 2666-2672 7 p.

Research output: Contribution to journalArticle

71 Scopus citations
2005

Clear cell sarcoma of the kidney: Up-regulation of neural markers with activation of the sonic hedgehog and Akt pathways

Cutcliffe, C., Kersey, D., Huang, C. C., Zeng, Y., Walterhouse, D. & Perlman, E. J., Nov 15 2005, In : Clinical Cancer Research. 11, 22, p. 7986-7994 9 p.

Research output: Contribution to journalArticle

90 Scopus citations

STAR proteins quaking-6 and GLD-1 regulate translation of the homologues GLI1 and tra-1 through a conserved RNA 3′UTR-based mechanism

Lakiza, O., Frater, L., Yoo, Y., Villavicencio, E., Walterhouse, D., Goodwin, E. B. & Iannaccone, P., Nov 1 2005, In : Developmental Biology. 287, 1, p. 98-110 13 p.

Research output: Contribution to journalArticle

19 Scopus citations
2004

Efficacy of topotecan and cyclophosphamide given in a phase II window trial in children with newly diagnosed metastatic rhabdomyosarcoma: A children's oncology group study

Walterhouse, D. O., Lyden, E. R., Breitfeld, P. P., Qualman, S. J., Wharam, M. D. & Meyer, W. H., Dec 1 2004, In : Journal of Clinical Oncology. 22, 8, p. 1398-1403 6 p.

Research output: Contribution to journalArticle

68 Scopus citations
2003

Sonic hedgehog signaling and Gli gene activation is essential for prostate ductal bud formation

Lamm, M. L., Catbagan, W. S., Laciak, R. J., Barnett, D. H., Hebner, C. M., Gaffield, W., Walterhouse, D., Iannaccone, P. & Bushman, W., Sep 1 2003, In : European Urology, Supplements. 2, 6, p. XCV

Research output: Contribution to journalArticle

2002

Cooperative E-box regulation of human GLI1 by TWIST and USF

Villavicencio, E. H., Yoon, J. W., Frank, D. J., Füchtbauer, E. M., Walterhouse, D. O. & Iannaccone, P. M., May 9 2002, In : Genesis. 32, 4, p. 247-258 12 p.

Research output: Contribution to journalArticle

31 Scopus citations

Gene expression profiling leads to identification of GLI1-binding elements in target genes and a role for multiple downstream pathways in GLI1-induced cell transformation

Yoon, J. W., Kita, Y., Frank, D. J., Majewski, R. R., Konicek, B. A., Nobrega, M. A., Jacob, H., Walterhouse, D. O. & Iannaccone, P. M., Feb 15 2002, In : Journal of Biological Chemistry. 277, 7, p. 5548-5555 8 p.

Research output: Contribution to journalArticle

258 Scopus citations

Long-term (15 years) outcome in an infant with metastatic adrenocortical carcinoma

De León, D. D., Lange, B. J., Walterhouse, D. O. & Moshang, T., Oct 1 2002, In : Journal of Clinical Endocrinology and Metabolism. 87, 10, p. 4452-4456 5 p.

Research output: Contribution to journalArticle

31 Scopus citations

Sonic hedgehog activates mesenchymal Gli1 expression during prostate ductal bud formation

Lamm, M. L. G., Catbagan, W. S., Laciak, R. J., Barnett, D. H., Hebner, C. M., Gaffield, W., Walterhouse, D., Iannaccone, P. & Bushman, W., Jan 1 2002, In : Developmental Biology. 249, 2, p. 349-366 18 p.

Research output: Contribution to journalArticle

132 Scopus citations
2001
14 Scopus citations
35 Scopus citations

Ifosfamide and etoposide are superior to vincristine and melphalan for pediatric metastatic rhabdomyosarcoma when administered with irradiation and combination chemotherapy: A report from the intergroup rhabdomyosarcoma study group

Breitfeld, P. P., Lyden, E., Beverly Raney, R., Teot, L. A., Wharam, M., Lobe, T., Crist, W. M., Maurer, H. M., Donaldson, S. S., Ruymann, F. B., Anderson, J. R., Andrassy, R. J., Arndt, C. A. S., Scott Baker, K., Barr, F. G., Archie Bleyer, W., Breitfeld, P., Breneman, J. C., Bridge, J., Brown, K. & 23 others, Grier, H. E., Hawkins, D., Houghton, P. J., Link, M., Meyer, W. H., Michalski, J., Murphy, S., Paidas, C. N., Pappo, A. S., Parham, D. M., Qualman, S. J., Robison, L., Sandler, E., Smith, L., Sorensen, P. H. B., Teot, L., Triche, T., Vietti, T. J., Walterhouse, D., Wiener, E. S., Wolden, S., Womer, R. & Leeson, J. L., 2001, In : American Journal of Pediatric Hematology/Oncology. 23, 4, p. 225-233 9 p.

Research output: Contribution to journalArticle

68 Scopus citations