Grants per year
Grants 2011 2022
Active
Mechanistic insights into the deleterious effects of SIRT2 in the heart under stress conditions
National Heart, Lung, and Blood Institute
12/1/17 → 11/30/21
Project: Research project
Proteins
Developed Countries
Heart Failure
Pressure
Dys-regulation of the MnSOD-Ac-ROS-HIF2a axis promotes IR / Cisplatin resistance phenotype
Abdulkadir, S. A. & Gius, D. R.
4/1/17 → 3/31/22
Project: Research project
Acetylation
Cisplatin
Superoxide Dismutase
Reactive Oxygen Species
Physiological Stress
Loss of Mitochondrial Sirt3, Decreased MnSOD Activity, and IR Induced Genomic Instability
Abdulkadir, S. A. & Gius, D. R.
4/9/15 → 3/31/20
Project: Research project
Genomic Instability
Neoplasms
NAD
CLOCK Proteins
Research
Finished
Avon Foundation for Breast Cancer Research and Care Program at the Robert H. Lurie Comprehensive Cancer Center of Northwestern University
Clare, S. E., Gius, D. R., Gius, D. R., Goel, M., Horikoshi, N., Khan, S. A., Khan, S. A. & Platanias, L. C.
Avon Breast Cancer Crusade LLC
10/1/17 → 12/31/18
Project: Research project
Therapeutic intervention of SIRT3 driven luminal B tumors with SOD
Gius, D. R. & Raparia, K.
Avon Breast Cancer Crusade LLC
10/1/16 → 9/30/17
Project: Research project
Diagnostic Services
Family Health
Mammography
Neoplasms
Breast
ROS and HIFa as molecular targets for chemoprevention in Sirt3 -/- breast cancers
8/1/16 → 7/31/18
Project: Research project
RHLCCC: Program Leaders
Backman, V., Benson III, A. B., Carthew, R. W., Chakravarti, D., Cheng, C., Eklund, E. A., Gius, D. R., Gordon, L. I., Green, K. J., Horvath, C. M., Hou, L., Khan, S. A., Kiyokawa, H., LaBonne, C., Penedo, F. J., Platanias, L. C., Simon, M. A., Spring, B. & Woloschak, G. E.
8/1/16 → 7/31/18
Project: Research project
Avon Foundation for Breast Cancer Research and Care Program at the Robert H. Lurie Comprehensive Cancer Center of Northwestern University
Bulun, S. E., Gius, D. R., Khan, S. A., Platanias, L. C., Wang, J. & Zhao, H.
Avon Products Foundation, Inc.
10/1/15 → 9/30/17
Project: Research project
Breast Neoplasms
Research
Breast
Neoplasms
Estrogens
A MnSOD Acetylation Mutant Mouse for Luminal B Endocrine Resistant Breast Cancer
Northwestern Memorial Hospital
9/1/15 → 8/31/19
Project: Research project
Acetylation
Breast Neoplasms
Neoplasms
Breast
Recurrence
Avon Foundation for Breast Cancer Research and Care Program at the Robert H. Lurie Comprehensive Cancer Center of Northwestern University
Gius, D. R. & Platanias, L. C.
Avon Products Foundation, Inc.
10/1/14 → 9/30/16
Project: Research project
Obesity
Breast Neoplasms
Research
Neoplasms
Therapeutic Intervention of SIRT3 Driven Luminal B Tumors with SOD Mimetics
Gius, D. R. & Raparia, K.
Avon Products Foundation, Inc.
10/1/13 → 9/30/16
Project: Research project
Breast Neoplasms
Neoplasms
Breast
Therapeutics
Early Detection of Cancer
RHLCCC: Program Leaders
Backman, V., Benson III, A. B., Carthew, R. W., Chakravarti, D., Eklund, E. A., Gius, D. R., Gordon, L. I., Green, K. J., Horvath, C. M., Khan, S. A., Kiyokawa, H., LaBonne, C., Penedo, F. J., Peter, M. E., Platanias, L. C., Simon, M. A., Spring, B. & Woloschak, G. E.
9/16/13 → 7/31/16
Project: Research project
Loss of mtSIRT3, Decreased MnSOD Activity, and IR Induced Genomic Instability
1/1/13 → 4/8/15
Project: Research project
GSK3B Mediates Radiation-Induced Cytotoxicity in Hippocampal Neurons
Ohio State University, National Cancer Institute
12/1/12 → 4/30/17
Project: Research project
Research Personnel
Radiation
Neurons
Calendars
ROS and HIFa as molecular targets for chemoprevention in Sirt3 -/- breast cancers
9/21/12 → 7/31/16
Project: Research project
SIRT3 is a Mitochondrial Tumor Suppressor in ER/PR Positive Mammary Tumors
9/19/12 → 7/31/17
Project: Research project
Sirt2 Regulation of KRAS is an Early Event in Pancreas Carcinogenesis.
Hirshberg Foundation for Pancreatic Cancer Research
8/1/12 → 12/31/13
Project: Research project
C-063: Fluorescent probes for live-cell imaging of sirtuin activity: Applications to breast cancer
Searle Funds at The Chicago Community Trust
1/1/11 → 12/31/17
Project: Research project