• 9010 Citations
1988 …2022
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Research Output 1988 2019

2019
6 Citations (Scopus)

Efferocytosis Fuels Requirements of Fatty Acid Oxidation and the Electron Transport Chain to Polarize Macrophages for Tissue Repair

Zhang, S., Weinberg, S., DeBerge, M., Gainullina, A., Schipma, M. J., Kinchen, J. M., Ben-Sahra, I., Gius, D. R., Yvan-Charvet, L., Chandel, N., Schumacker, P. T. & Thorp, E. B., Feb 5 2019, In : Cell Metabolism. 29, 2, p. 443-456.e5

Research output: Contribution to journalArticle

Electron Transport
Fatty Acids
Macrophages
Interleukin-10
NAD

Homeostatic roles of STING in cell proliferation and chromosomal instability

Gius, D. R. & Zhu, Y., Jan 1 2019, In : Cancer Research. 79, 7, p. 1295-1296 2 p.

Research output: Contribution to journalArticle

Chromosomal Instability
Cell Proliferation
Genes
Neoplasms
Cell Cycle
1 Citation (Scopus)

Lysine 68 acetylation directs MnSOD as a tetrameric detoxification complex versus a monomeric tumor promoter

Zhu, Y., Zou, X., Dean, A. E., Brien, J. O., Gao, Y., Tran, E. L., Park, S. H., Liu, G., Kieffer, M. B., Jiang, H., Stauffer, M. E., Hart, R., Quan, S., Satchell, K. J. F., Horikoshi, N., Bonini, M. & Gius, D. R., Dec 1 2019, In : Nature communications. 10, 1, 2399.

Research output: Contribution to journalArticle

Open Access
acetylation
Acetylation
Detoxification
inorganic peroxides
lysine
1 Citation (Scopus)

Sirtuin 2–mediated deacetylation of cyclin-dependent kinase 9 promotes STAT1 signaling in type I interferon responses

Kosciuczuk, E. M., Mehrotra, S., Nora Vaz Saleiro, D., Kroczynska, B., Majchrzak-Kita, B., Lisowski, P., Driehaus, C., Rogalska, A., Turner, A., Lienhoop, T., Gius, D. R., Fish, E. N., Vasilopoulos, A. & Platanias, L. C., Jan 1 2019, In : Journal of Biological Chemistry. 294, 3, p. 827-837 11 p.

Research output: Contribution to journalArticle

Cyclin-Dependent Kinase 9
Interferon Type I
Sirtuin 2
Interferons
Transcription
2018
13 Citations (Scopus)

Emerging evidence for targeting mitochondrial metabolic dysfunction in cancer therapy

Zhu, Y., Dean, A. E., Horikoshi, N., Heer, C., Spitz, D. R. & Gius, D. R., Aug 31 2018, In : Journal of Clinical Investigation. 128, 9, p. 3682-3691 10 p.

Research output: Contribution to journalReview article

Oxidation-Reduction
Neoplasms
Therapeutics
Electron Transport
NADP
10 Citations (Scopus)

Exosomes as a Drug Delivery System in Cancer Therapy: Potential and Challenges

Kibria, G., Ramos, E. K., Wan, Y., Gius, D. R. & Liu, H., Sep 4 2018, In : Molecular Pharmaceutics. 15, 9, p. 3625-3633 9 p.

Research output: Contribution to journalReview article

Exosomes
Drug Delivery Systems
Neoplasms
Therapeutics
Pharmaceutical Preparations

Glycogen phosphorylase: A novel biomarker in doxorubicin-induced cardiac injury

Zhu, Y. & Gius, D. R., Apr 1 2018, In : Clinical Cancer Research. 24, 7, p. 1516-1517 2 p.

Research output: Contribution to journalArticle

Glycogen Phosphorylase
Doxorubicin
Biomarkers
Drug Therapy
Wounds and Injuries
6 Citations (Scopus)

Inhibition of sirtuin 6 induces neuroblastoma differentiation

Song, H. Y., Rellinger, E. J., Park, S. H., Paul, P., Qiao, J., Vasilopoulos, A., Ozden, O., Gius, D. R. & Chung, D. H., Feb 1 2018, In : Anticancer research. 38, 2, p. 647-654 8 p.

Research output: Contribution to journalArticle

Sirtuins
Neuroblastoma
Niacinamide
G1 Phase Cell Cycle Checkpoints
Genomic Instability
1 Citation (Scopus)

Loss of Sirt2 increases and prolongs a caerulein-induced pancreatitis permissive phenotype and induces spontaneous oncogenic Kras mutations in mice

Quan, S., Principe, D. R., Dean, A. E., Park, S. H., Grippo, P. J., Gius, D. R. & Horikoshi, N., Dec 1 2018, In : Scientific reports. 8, 1, 16501.

Research output: Contribution to journalArticle

Ceruletide
Pancreatitis
Phenotype
Mutation
Pancreas

SIRT2 knockout exacerbates insulin resistance in high fat-fed mice

Lantier, L., Williams, A. S., Hughey, C. C., Bracy, D. P., James, F. D., Ansari, M. A., Gius, D. R. & Wasserman, D. H., Dec 1 2018, In : PloS one. 13, 12, e0208634.

Research output: Contribution to journalArticle

Acetylation
insulin resistance
Knockout Mice
Insulin Resistance
Fats
2017
27 Citations (Scopus)

Loss of NAD-Dependent Protein Deacetylase Sirtuin-2 Alters Mitochondrial Protein Acetylation and Dysregulates Mitophagy

Liu, G., Park, S. H., Imbesi, M., Nathan, W. J., Zou, X., Zhu, Y., Jiang, H., Parisiadou, L. & Gius, D. R., May 20 2017, In : Antioxidants and Redox Signaling. 26, 15, p. 846-863 18 p.

Research output: Contribution to journalArticle

Sirtuin 2
Mitochondrial Degradation
Acetylation
Mitochondrial Proteins
NAD
6 Citations (Scopus)

Loss of Nrf2 promotes alveolar type 2 cell loss in irradiated, fibrotic lung

Traver, G., Mont, S., Gius, D. R., Lawson, W. E., Ding, G. X., Sekhar, K. R. & Freeman, M. L., Nov 1 2017, In : Free Radical Biology and Medicine. 112, p. 578-586 9 p.

Research output: Contribution to journalArticle

Alveolar Epithelial Cells
Radiation
Lung
Fibrosis
Myofibroblasts
23 Citations (Scopus)

Manganese superoxide dismutase (SOD2): is there a center in the universe of mitochondrial redox signaling?

Zou, X., Ratti, B. A., O’Brien, J. G., Lautenschlager, S. O., Gius, D. R., Bonini, M. G. & Zhu, Y., Aug 1 2017, In : Journal of Bioenergetics and Biomembranes. 49, 4, p. 325-333 9 p.

Research output: Contribution to journalReview article

Superoxide Dismutase
Oxidation-Reduction
Mitochondria
Selenocysteine
Methionine
20 Citations (Scopus)

Prolonged fasting suppresses mitochondrial NLRP3 inflammasome assembly and activation via SIRT3-mediated activation of superoxide dismutase 2

Traba, J., Geiger, S. S., Kwarteng-Siaw, M., Han, K., Ra, O. H., Siegel, R. M., Gius, D. R. & Sack, M. N., Jan 1 2017, In : Journal of Biological Chemistry. 292, 29, p. 12153-12164 12 p.

Research output: Contribution to journalArticle

Inflammasomes
Fasting
Chemical activation
Macrophages
Knockout Mice
16 Citations (Scopus)

SIRT3 deficiency promotes lung fibrosis by augmenting alveolar epithelial cell mitochondrial DNA damage and apoptosis

Jablonski, R. P., Kim, S., Cheresh, P., Williams, D. B., Morales-Nebreda, L., Cheng, Y., Yeldandi, A. V., Bhorade, S. M., Pardo, A., Selman, M., Ridge, K. M., Gius, D. R., Budinger, GR. S. & Kamp, D. W., Jun 1 2017, In : FASEB Journal. 31, 6, p. 2520-2532 13 p.

Research output: Contribution to journalArticle

Sirtuin 3
Alveolar Epithelial Cells
Mitochondrial DNA
DNA Damage
Fibrosis
14 Citations (Scopus)

SIRT3-mediated dimerization of IDH2 directs cancer cell metabolism and tumor growth

Zou, X., Zhu, Y., Park, S. H., Liu, G., O'Brien, J., Jiang, H. & Gius, D. R., Aug 1 2017, In : Cancer Research. 77, 15, p. 3990-3999 10 p.

Research output: Contribution to journalArticle

Dimerization
Acetylation
Growth
Neoplasms
Phenotype
19 Citations (Scopus)

Sirt3 protects dopaminergic neurons from mitochondrial oxidative stress

Shi, H., Deng, H-X., Gius, D. R., Schumacker, P. T., Surmeier Jr, D. J. & Ma, Y., May 15 2017, In : Human molecular genetics. 26, 10, p. 1915-1926 12 p.

Research output: Contribution to journalArticle

Sirtuin 3
Dopaminergic Neurons
Oxidative Stress
Superoxide Dismutase
Acetylation
26 Citations (Scopus)

Sirtuin 2 regulates cellular iron homeostasis via deacetylation of transcription factor NRF2

Yang, X., Park, S. H., Chang, H. C., Shapiro, J. S., Vasilopoulos, A., Sawicki, K. T., Chen, C., Shang, M., Burridge, P., Epting, C. L., Wilsbacher, L. D., Jenkitkasemwong, S., Knutson, M., Gius, D. R. & Ardehali, H., Apr 3 2017, In : Journal of Clinical Investigation. 127, 4, p. 1505-1516 12 p.

Research output: Contribution to journalArticle

Sirtuin 2
Homeostasis
Transcription Factors
Iron
Lysine
2016
17 Citations (Scopus)

ATRIP Deacetylation by SIRT2 Drives ATR Checkpoint Activation by Promoting Binding to RPA-ssDNA

Zhang, H., Head, P. S. E., Daddacha, W., Park, S. H., Li, X., Pan, Y., Madden, M. Z., Duong, D. M., Xie, M., Yu, B., Warren, M. D., Liu, E. A., Dhere, V. R., Li, C., Pradilla, I., Torres, M. A., Wang, Y., Dynan, W. S., Doetsch, P. W., Deng, X. & 3 others, Seyfried, N. T., Gius, D. R. & Yu, D. S., Feb 16 2016, In : Cell reports. 14, 6, p. 1435-1447 13 p.

Research output: Contribution to journalArticle

Sirtuin 2
Replication Protein A
Ataxia Telangiectasia
Single-Stranded DNA
Chemical activation
7 Citations (Scopus)
Leiomyoma
Superoxide Dismutase
Oxidation-Reduction
Myometrium
Cell Survival
34 Citations (Scopus)

G protein-coupled bile acid receptor TGR5 activation inhibits kidney disease in obesity and diabetes

Wang, X. X., Edelstein, M. H., Gafter, U., Qiu, L., Luo, Y., Dobrinskikh, E., Lucia, S., Adorini, L., D'Agati, V. D., Levi, J., Rosenberg, A., Kopp, J. B., Gius, D. R., Saleem, M. A. & Levi, M., May 1 2016, In : Journal of the American Society of Nephrology. 27, 5, p. 1362-1378 17 p.

Research output: Contribution to journalArticle

Kidney Diseases
Bile Acids and Salts
GTP-Binding Proteins
Obesity
Kidney
17 Citations (Scopus)

Manganese Superoxide Dismutase Acetylation and Dysregulation, Due to Loss of SIRT3 Activity, Promote a Luminal B-Like Breast Carcinogenic-Permissive Phenotype

Zou, X., Santa-Maria, C. A., O'Brien, J., Gius, D. R. & Zhu, Y., Aug 20 2016, In : Antioxidants and Redox Signaling. 25, 6, p. 326-336 11 p.

Research output: Contribution to journalReview article

Acetylation
Superoxide Dismutase
Breast
Breast Neoplasms
Phenotype
8 Citations (Scopus)

SIRT2 deletion enhances KRAS-induced tumorigenesis in vivo by regulating K147 acetylation status

Song, H. Y., Biancucci, M., Kang, H. J., O'Callaghan, C., Park, S. H., Principe, D. R., Jiang, H., Yan, Y., Satchell, K. F., Raparia, K., Gius, D. & Vassilopoulos, A., Jan 1 2016, In : Oncotarget. 7, 49, p. 80336-80349 14 p.

Research output: Contribution to journalArticle

Acetylation
Carcinogenesis
Phenotype
Post Translational Protein Processing
Mass Spectrometry
30 Citations (Scopus)

SIRT2-mediated deacetylation and tetramerization of pyruvate kinase directs glycolysis and tumor growth

Park, S. H., Ozden, O., Liu, G., Song, H. Y., Zhu, Y., Yan, Y., Zou, X., Kang, H. J., Jiang, H., Principe, D. R., Cha, Y. I., Roh, M., Vasilopoulos, A. & Gius, D. R., Jul 1 2016, In : Cancer Research. 76, 13, p. 3802-3812 11 p.

Research output: Contribution to journalArticle

Pyruvate Kinase
Glycolysis
Sirtuins
Acetylation
Growth
2015
4 Citations (Scopus)

Antioxidant inhibition of steady-state reactive oxygen species and cell growth in neuroblastoma

Zhu, Y., Paul, P., Lee, S., Craig, B. T., Rellinger, E. J., Qiao, J., Gius, D. R. & Chung, D. H., Sep 1 2015, In : Surgery (United States). 158, 3, p. 827-836 10 p.

Research output: Contribution to journalArticle

Neuroblastoma
Reactive Oxygen Species
Antioxidants
Growth
Hypoxia-Inducible Factor 1
32 Citations (Scopus)

CDK1-mediated SIRT3 activation enhances mitochondrial function and tumor radioresistance

Liu, R., Fan, M., Candas, D., Qin, L., Zhang, X., Eldridge, A., Zou, J. X., Zhang, T., Juma, S., Jin, C., Li, R. F., Perks, J., Sun, L. Q., Vaughan, A. T. M., Hai, C. X., Gius, D. R. & Li, J. J., Sep 1 2015, In : Molecular cancer therapeutics. 14, 9, p. 2090-2102 13 p.

Research output: Contribution to journalArticle

Neoplasms
Radiation
Mitochondria
Mitochondrial Proteins
Phosphorylation

Changes in gene expression in SIRT3 knockout liver cells

Tao, R., Leclerc, J., Yildiz, K., Park, S. H., Jung, B., Gius, D. R. & Özden, Ö., Jan 1 2015, In : Turkish Journal of Biology. 39, 3, p. 380-387 8 p.

Research output: Contribution to journalArticle

hepatocytes
Breast Neoplasms
Oncogenes
Transcriptome
Gene Expression
123 Citations (Scopus)

Honokiol blocks and reverses cardiac hypertrophy in mice by activating mitochondrial Sirt3

Pillai, V. B., Samant, S., Sundaresan, N. R., Raghuraman, H., Kim, G., Bonner, M. Y., Arbiser, J. L., Walker, D. I., Jones, D. P., Gius, D. R. & Gupta, M. P., Apr 14 2015, In : Nature communications. 6, 6656.

Research output: Contribution to journalArticle

Cardiomegaly
mice
acetylation
oxygen consumption
mitochondria
49 Citations (Scopus)

SIRT3 is crucial for maintaining skeletal muscle insulin action and protects against severe insulin resistance in high-fat-fed mice

Lantier, L., Williams, A. S., Williams, I. M., Yang, K. K., Bracy, D. P., Goelzer, M., James, F. D., Gius, D. R. & Wasserman, D. H., Sep 1 2015, In : Diabetes. 64, 9, p. 3081-3092 12 p.

Research output: Contribution to journalArticle

Sirtuin 3
Insulin Resistance
Skeletal Muscle
Fats
Insulin
23 Citations (Scopus)

Site-specific processing of Ras and Rap1 Switch i by a MARTX toxin effector domain

Antic, I., Biancucci, M., Zhu, Y., Gius, D. R. & Satchell, K. J. F., Jun 8 2015, In : Nature communications. 6, 7396.

Research output: Contribution to journalArticle

effectors
Sarcoma
rats
Rats
switches
12 Citations (Scopus)

The Makes Caterpillars Floppy (MCF)-like domain of Vibrio vulnificus induces mitochondrion-mediated apoptosis

Agarwal, S., Zhu, Y., Gius, D. R. & Satchell, K. J. F., Jan 1 2015, In : Infection and Immunity. 83, 11, p. 4392-4403 12 p.

Research output: Contribution to journalArticle

Vibrio vulnificus
Mitochondria
Apoptosis
Cysteine Proteases
Poly(ADP-ribose) Polymerases
7 Citations (Scopus)

WEE1 murine deficiency induces hyper-activation of APC/C and results in genomic instability and carcinogenesis

Vasilopoulos, A., Tominaga, Y., Kim, H. S., Lahusen, T., Li, B., Yu, H., Gius, D. R. & Deng, C. X., Jun 4 2015, In : Oncogene. 34, 23, p. 3023-3035 13 p.

Research output: Contribution to journalArticle

Genomic Instability
Mitosis
Carcinogenesis
Breast
Anaphase-Promoting Complex-Cyclosome
2014
45 Citations (Scopus)

Aberrant IKKα and IKKβ cooperatively activate NF-κB and induce EGFR/AP1 signaling to promote survival and migration of head and neck cancer

Nottingham, L. K., Yan, C. H., Yang, X., Si, H., Coupar, J., Bian, Y., Cheng, T. F., Allen, C., Arun, P., Gius, D., Dang, L., Van Waes, C. & Chen, Z., Feb 27 2014, In : Oncogene. 33, 9, p. 1135-1147 13 p.

Research output: Contribution to journalArticle

Head and Neck Neoplasms
Transcription Factor AP-1
Epidermal Growth Factor Receptor
Cell Movement
Transcription Factors
84 Citations (Scopus)

Cell type-restricted activity of hnRNPM promotes breast cancer metastasis via regulating alternative splicing

Xu, Y., Gao, X. D., Lee, J. H., Huang, H., Tan, H., Ahn, J., Reinke, L. M., Peter, M. E., Feng, Y., Gius, D., Siziopikou, K. P., Peng, J., Xiao, X. & Cheng, C., Jun 1 2014, In : Genes and Development. 28, 11, p. 1191-1203 13 p.

Research output: Contribution to journalArticle

Heterogeneous-Nuclear Ribonucleoprotein Group M
Alternative Splicing
Breast Neoplasms
Neoplasm Metastasis
Epithelial-Mesenchymal Transition
33 Citations (Scopus)

Decreased mitochondrial SIRT3 expression is a potential molecular biomarker associated with poor outcome in breast cancer

Desouki, M. M., Doubinskaia, I., Gius, D. & Abdulkadir, S. A., Jan 1 2014, In : Human Pathology. 45, 5, p. 1071-1077 7 p.

Research output: Contribution to journalArticle

Biomarkers
Breast Neoplasms
Tumor Suppressor Proteins
Epithelium
Recurrence
70 Citations (Scopus)
Superoxide Dismutase
Carcinogenesis
Aging of materials
Mitochondria
Proteins
75 Citations (Scopus)

SIRT3 deacetylates and increases pyruvate dehydrogenase activity in cancer cells

Ozden, O., Park, S. H., Wagner, B. A., Song, H. Y., Zhu, Y., Vasilopoulos, A., Jung, B., Buettner, G. R. & Gius, D. R., Jan 1 2014, In : Free Radical Biology and Medicine. 76, p. 163-172 10 p.

Research output: Contribution to journalArticle

Pyruvate Dehydrogenase (Lipoamide)
Pyruvic Acid
Oxidoreductases
Cells
Acetylation
72 Citations (Scopus)

SIRT3 deacetylates ATP synthase F1 complex proteins in response to nutrient-and exercise-induced stress

Vasilopoulos, A., Pennington, J. D., Andresson, T., Rees, D. M., Bosley, A. D., Fearnley, I. M., Ham, A., Flynn, C. R., Hill, S., Rose, K. L., Kim, H. S., Deng, C. X., Walker, J. E. & Gius, D. R., Aug 1 2014, In : Antioxidants and Redox Signaling. 21, 4, p. 551-564 14 p.

Research output: Contribution to journalArticle

Nutrients
Adenosine Triphosphate
Food
Proteins
Homeostasis
8 Citations (Scopus)

Strategies of dose escalation in the treatment of locally advanced non-small cell lung cancer: Image guidance and beyond

Chi, A., Nguyen, N. P., Welsh, J. S., Tse, W., Monga, M., Oduntan, O., Almubarak, M., Rogers, J., Remick, S. C. & Gius, D. R., Jan 1 2014, In : Frontiers in Oncology. 4 JUN, 156.

Research output: Contribution to journalReview article

Non-Small Cell Lung Carcinoma
Radiation
Conformal Radiotherapy
Positron-Emission Tomography
Radiotherapy
18 Citations (Scopus)

Superoxide mediates acute liver injury in irradiated mice lacking Sirtuin 3

Coleman, M. C., Olivier, A. K., Jacobus, J. A., Mapuskar, K. A., Mao, G., Martin, S. M., Riley, D. P., Gius, D. R. & Spitz, D. R., Mar 20 2014, In : Antioxidants and Redox Signaling. 20, 9, p. 1423-1435 13 p.

Research output: Contribution to journalArticle

Sirtuin 3
Superoxides
Liver
Wounds and Injuries
Whole-Body Irradiation
2013
35 Citations (Scopus)

Bioenergetic and autophagic control by Sirt3 in response to nutrient deprivation in mouse embryonic fibroblasts

Liang, Q., Benavides, G. A., Vasilopoulos, A., Gius, D. R., Darley-Usmar, V. & Zhang, J., Sep 1 2013, In : Biochemical Journal. 454, 2, p. 249-257 9 p.

Research output: Contribution to journalArticle

Sirtuin 3
Fibroblasts
Energy Metabolism
Nutrients
Food
3 Citations (Scopus)

Cancer of the Lung: Non-Small Cell Lung Cancer and Small Cell Lung Cancer

Horn, L., Eisenberg, R., Gius, D. R., Kimmelshue, K. N., Massion, P. P., Putnam, J. B., Robinson, C. G. & Carbone, D. P., Oct 22 2013, Abeloff's Clinical Oncology: Fifth Edition. Elsevier Inc, p. 1143-1192 50 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

281 Citations (Scopus)

Circadian clock NAD+ cycle drives mitochondrial oxidative metabolism in mice

Bien, C., Affinati, A. H., Ramsey, K. M., Kuo, H. Y., Yu, W., Sena, L. A., Ilkayeva, O., Marcheva, B., Kobayashi, Y., Omura, C., Levine, D. C., Bacsik, D. J., Gius, D. R., Newgard, C. B., Goetzman, E., Chandel, N., Denu, J. M., Mrksich, M. & Bass, J., Jan 1 2013, In : Science. 342, 6158, 1243417.

Research output: Contribution to journalArticle

Circadian Clocks
NAD
Acetylation
Sirtuin 3
Fasting
23 Citations (Scopus)

Genotype and tumor locus determine expression profile of pseudohypoxic pheochromocytomas and paragangliomas

Shankavaram, U., Fliedner, S. M. J., Elkahloun, A. G., Barb, J. J., Munson, P. J., Huynh, T. T., Matro, J. C., Turkova, H., Marston Linehan, W., Timmers, H. J., Tischler, A. S., Powers, J. F., de Krijger, R., Baysal, B. E., Takacova, M., Pastorekova, S., Gius, D. R., Lehnert, H., Camphausen, K. & Pacak, K., Jan 1 2013, In : Neoplasia (United States). 15, 4, p. 435-447 13 p.

Research output: Contribution to journalArticle

Paraganglioma
Pheochromocytoma
Genotype
Neoplasms
Neck
2 Citations (Scopus)

Low-dose radiation-induced enhancement of thymic lymphomagenesis in lck-bax mice is dependent on LET and gender

Jacobus, J. A., Duda, C. G., Coleman, M. C., Martin, S. M., Mapuskar, K., Mao, G., Smith, B. J., Aykin-Burns, N., Guida, P., Gius, D. R., Domann, F. E., Knudson, C. M. & Spitz, D. R., Aug 1 2013, In : Radiation Research. 180, 2, p. 156-165 10 p.

Research output: Contribution to journalArticle

Linear Energy Transfer
Superoxides
Sirtuin 3
mice
inorganic peroxides
8 Citations (Scopus)

Metabolic regulation of Sirtuins upon fasting and the implication for cancer

Zhu, Y., Yan, Y., Gius, D. R. & Vasilopoulos, A., Nov 1 2013, In : Current Opinion in Oncology. 25, 6, p. 630-636 7 p.

Research output: Contribution to journalReview article

Sirtuins
Fasting
Neoplasms
Carcinogenesis
Glycolysis
41 Citations (Scopus)

SIRT2 directs the replication stress response through CDK9 deacetylation

Zhang, H., Park, S. H., Pantazides, B. G., Karpiuk, O., Warren, M. D., Hardy, C. W., Duong, D. M., Park, S. J., Kim, H. S., Vasilopoulos, A., Seyfried, N. T., Johnsen, S. A., Gius, D. R. & Yu, D. S., Aug 13 2013, In : Proceedings of the National Academy of Sciences of the United States of America. 110, 33, p. 13546-13551 6 p.

Research output: Contribution to journalArticle

Sirtuin 2
Cyclin-Dependent Kinase 9
Cyclin T
Replication Protein A
Genome
2012
34 Citations (Scopus)

Exploring the electrostatic repulsion model in the role of Sirt3 in directing MnSOD acetylation status and enzymatic activity

Zhu, Y., Park, S. H., Ozden, O., Kim, H. S., Jiang, H., Vassilopoulos, A., Spitz, D. R. & Gius, D., Aug 15 2012, In : Free Radical Biology and Medicine. 53, 4, p. 828-833 6 p.

Research output: Contribution to journalReview article

Acetylation
Static Electricity
Superoxide Dismutase
Electrostatics
Reactive Oxygen Species
3 Citations (Scopus)

Oxidative stress in cancer biology and therapy

Spitz, D. R., Dornfeld, K. J., Krishnan, K. & Gius, D., Jan 1 2012, Humana Press Inc. 460 p.

Research output: Book/ReportBook

Oxidative stress
Oxidative Stress
Neoplasms
Tissue
Free Radicals
42 Citations (Scopus)

Pim1 kinase is required to maintain tumorigenicity in MYC-expressing prostate cancer cells

Wang, J., Anderson, P. D., Luo, W., Gius, D., Roh, M. & Abdulkadir, S. A., Apr 5 2012, In : Oncogene. 31, 14, p. 1794-1803 10 p.

Research output: Contribution to journalArticle

Prostatic Neoplasms
Phosphotransferases
Prostate
cdc Genes
myc Genes