Dr. De Ranieri’s clinical interests are diverse. She sees children with a broad range of systemic autoimmune diseases, such as childhood lupus, dermatomyositis, periodic fevers, juvenile arthritis, and vasculitis. Dr. De Ranieri uses Musculoskeletal Ultrasound (MSK US) in her practice to help accurately diagnose, monitor and treat (via guided intervention) joint and tendon disease in children with JIA. She has served on the Examination Development Committee for the Rheumatology MSK US Certification Exam, and she has taught both beginning and advanced musculoskeletal ultrasound courses at national conferences. Dr De Ranieri will be serving as a faculty mentor for USSONAR (Ultrasound School of North American Rheumatologists) during the 2019-2020 academic year. Dr. De Ranieri also enjoys teaching and is the Fellowship Program Director and Director of Medical Education in the division of Rheumatology.

Dr. De Ranieri's research interests are mainly focused on the use of MSK US in JIA, including standardization of the methodology used both for image acquisition and pathology grading in children with JIA, using MSK US to evaluate for subclinical disease in children with JIA, and she is also part of a multicenter study using minimally-invasive ultrasound-guided synovial biopsies to look for biomarkers of disease, which may have a role in both predicting prognosis and directing more targeted therapies in children with JIA. She also participates in studies of new drugs for treating children with JIA.

Dr De Ranieri’s main clinical focus is Juvenile Idiopathic Arthritis, but she also sees patients with a variety of autoimmune disease, including Uveitis, Systemic Lupus Erythematosus, Juvenile Dermatomyositis, Vasculitis, Sjogren’s Syndrome, Sarcoidosis, Periodic Fever Syndromes, etc.