Grants per year
Personal profile
Research Interests
Dr. Denise Scholtens is interested in statistical problems arising from high-throughput omics data. She is Chief of the Division of Biostatistics and Associate Director for Biostatistics in the Robert H. Lurie Comprehensive Cancer Center Quantitative Data Sciences Core where she collaborates on a variety of basic science and clinical cancer studies. She also directs the Data Coordinating Center for the international, observational Hyperglycemia and Adverse Pregnancy Outcome (HAPO) Follow-Up Study and serves as the primary statistician for the HAPO Metabolomics and Integrated Omics Studies.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
PhD, Biostatistics, Harvard University
… → 2004
Research interests keywords
- Bioinformatics
- Biostatistics
- Computational Biology
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Multi-Institutional Phase 2/3 Trial of Valproic Acid in Patients with Moderate to Severe Traumatic Brain Injury
Alam, H. B. (PD/PI), Hill, V. B. (Co-Investigator), Katsaggelos, A. K. (Co-Investigator), Parrish, T. B. (Co-Investigator), Scholtens, D. M. (Co-Investigator) & Tatebe, L. C. (Co-Investigator)
U.S. Army Medical Research and Materiel Command
5/1/24 → 4/30/29
Project: Research project
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The Neu-Lung Consortium: Neutrophilic Mechanisms of Inflammation, Injury, and Repair in Lung and Airways Diseases
Fourati, S. (Co-Investigator), Luo, Y. (Co-Investigator), Morales-Nebreda, L. (Co-Investigator), Scholtens, D. M. (Co-Investigator), Wunderink, R. G. (Co-Investigator) & Walunas, T. L. (Other)
National Institute of Allergy and Infectious Diseases
4/1/24 → 3/31/29
Project: Research project
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Comparative effective of two aspirin doses for prevention of hypertensive disorders of pregnancy
Scholtens, D. M. (PD/PI) & Gill, N. P. (Co-Investigator)
Ohio State University, Patient-Centered Outcomes Research Institute
3/1/24 → 2/28/25
Project: Research project
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Hyperbaric Oxygen Therapy for Ulcerative Colitis Patients Hospitalized for Moderate to Severe Flares: A Phase 3 Multi-Center, Randomized, Double-Blind, Sham-Controlled Trial
Bonner, L. B. (PD/PI), Bonner, L. B. (PD/PI), Dulai, P. S. (PD/PI), Dulai, P. S. (PD/PI), Hanauer, S. B. (Co-Investigator), Hanauer, S. B. (Co-Investigator), Hanauer, S. B. (Co-Investigator), Hirano, I. (Co-Investigator), Hirano, I. (Co-Investigator), Scholtens, D. M. (Co-Investigator), Scholtens, D. M. (Co-Investigator), Sumagin, R. (Co-Investigator), Sumagin, R. (Co-Investigator), Sumagin, R. (Co-Investigator), Yang, G.-Y. (Co-Investigator), Yang, G.-Y. (Co-Investigator) & Yang, G.-Y. (Co-Investigator)
National Institute of Diabetes and Digestive and Kidney Diseases
3/15/23 → 2/29/28
Project: Research project
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Hyperglycemia and Adverse Pregnancy Outcome Study-
Lloyd-Jones, D. M. (PD/PI), Allen, N. B. (Co-Investigator), Bonner, L. B. (Co-Investigator), Lowe Jr, W. L. (Co-Investigator), Scholtens, D. M. (Co-Investigator), Lowe Jr, W. L. (Other) & Metzger, B. E. (Other)
Ann & Robert H. Lurie Children's Hospital of Chicago, National Heart, Lung, and Blood Institute
3/1/23 → 2/29/28
Project: Research project
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Cohort Profile: Dementia Risk Prediction Project (DRPP)
Krefman, A. E., Stephen, J., Carolan, P., Sedaghat, S., Mansolf, M., Soumare, A., Gross, A. L., Aiello, A. E., Singh-Manoux, A., Ikram, M. A., Helmer, C., Tzourio, C., Satizabal, C., Levine, D. A., Lloyd-Jones, D., Briceño, E. M., Sorond, F. A., Wolters, F. J., Himali, J. & Launer, L. J. & 10 others, , Feb 1 2024, In: International journal of epidemiology. 53, 1, dyae012.Research output: Contribution to journal › Article › peer-review
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Elevated Blood Pressure in Pregnancy and Long-Term Cardiometabolic Health Outcomes
Field, C., Grobman, W. A., Wu, J., Kuang, A., Scholtens, D. M., Lowe, W. L., Shah, N. S., Khan, S. S. & Venkatesh, K. K., Sep 1 2024, In: Obstetrics and gynecology. 144, 3, p. 395-402 8 p.Research output: Contribution to journal › Article › peer-review
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Impact of hypertensive disorders of pregnancy and gestational diabetes mellitus on offspring cardiovascular health in early adolescence
Venkatesh, K. K., Perak, A. M., Wu, J., Catalano, P., Josefon, J. L., Costantine, M. M., Landon, M. B., Lancki, N., Scholtens, D., Lowe, W., Khan, S. S. & Grobman, W. A., 2024, (Accepted/In press) In: American journal of obstetrics and gynecology.Research output: Contribution to journal › Article › peer-review
Open Access -
Integrating multiple lines of evidence to assess the effects of maternal BMI on pregnancy and perinatal outcomes
Borges, M. C., Clayton, G. L., Freathy, R. M., Felix, J. F., Fernández-Sanlés, A., Soares, A. G., Kilpi, F., Yang, Q., McEachan, R. R. C., Richmond, R. C., Liu, X., Skotte, L., Irizar, A., Hattersley, A. T., Bodinier, B., Scholtens, D. M., Nohr, E. A., Bond, T. A., Hayes, M. G. & West, J. & 20 others, , Dec 2024, In: BMC Medicine. 22, 1, 32.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
Leptin and adiposity measures from birth to later childhood: Findings from the Hyperglycemia and Adverse Pregnancy Outcomes Follow-Up Study
DeLacey, S., Gurra, M., Arzu, J., Lowe, L. P., Lowe, W. L., Scholtens, D. M. & Josefson, J. L., Feb 2024, In: Pediatric Obesity. 19, 2, e13087.Research output: Contribution to journal › Article › peer-review
Open Access
Datasets
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Additional file 3: Table S5. of Transversions have larger regulatory effects than transitions
Guo, C. (Creator), McDowell, I. C. (Creator), Nodzenski, M. (Creator), Scholtens, D. M. (Creator), Allen, A. S. (Creator), Lowe, W. L. (Creator) & Reddy, T. E. (Creator), figshare, 2017
DOI: 10.6084/m9.figshare.c.3784286_d3, https://springernature.figshare.com/articles/dataset/Additional_file_3_Table_S5_of_Transversions_have_larger_regulatory_effects_than_transitions/5027078
Dataset
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Synuclein-γ (SNCG) expression in ovarian cancer is associated with high-risk clinicopathologic disease
Strohl, A. (Creator), Mori, K. (Creator), Akers, S. (Creator), Bshara, W. (Contributor), Buttin, B. (Creator), Frederick, P. J. (Creator), Helenowski, I. B. (Creator), Morrison, C. D. (Creator), Odunsi, K. (Contributor), Schink, J. C. (Creator), Scholtens, D. M. (Creator), Wei, J.-J. (Creator) & Kim, J. J. (Contributor), figshare, 2016
DOI: 10.6084/m9.figshare.c.3621737, https://figshare.com/collections/Synuclein-_SNCG_expression_in_ovarian_cancer_is_associated_with_high-risk_clinicopathologic_disease/3621737
Dataset
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Additional file 5: Table S2. of Transversions have larger regulatory effects than transitions
Guo, C. (Creator), McDowell, I. C. (Creator), Nodzenski, M. (Creator), Scholtens, D. M. (Creator), Allen, A. S. (Creator), Lowe, W. L. (Creator) & Reddy, T. E. (Creator), figshare, 2017
DOI: 10.6084/m9.figshare.c.3784286_d5, https://springernature.figshare.com/articles/dataset/Additional_file_5_Table_S2_of_Transversions_have_larger_regulatory_effects_than_transitions/5027114
Dataset
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Transversions have larger regulatory effects than transitions
Guo, C. (Creator), McDowell, I. C. (Creator), Nodzenski, M. (Creator), Scholtens, D. M. (Creator), Allen, A. S. (Creator), Lowe, W. L. (Creator) & Reddy, T. E. (Creator), figshare, 2017
DOI: 10.6084/m9.figshare.c.3784286, https://figshare.com/collections/Transversions_have_larger_regulatory_effects_than_transitions/3784286
Dataset
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Additional file 7: Table S4. of Transversions have larger regulatory effects than transitions
Guo, C. (Creator), McDowell, I. C. (Creator), Nodzenski, M. (Creator), Scholtens, D. M. (Creator), Allen, A. S. (Creator), Lowe, W. L. (Creator) & Reddy, T. E. (Creator), figshare, 2017
DOI: 10.6084/m9.figshare.c.3784286_d7, https://springernature.figshare.com/articles/dataset/Additional_file_7_Table_S4_of_Transversions_have_larger_regulatory_effects_than_transitions/5027144
Dataset