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Denise M Scholtens

  • 2619 Citations
20002020

Research output per year

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Personal profile

Research Interests

Dr. Denise Scholtens is interested in statistical problems arising from high-throughput omics data. She is Chief of the Division of Biostatistics and Associate Director for Biostatistics in the Robert H. Lurie Comprehensive Cancer Center Quantitative Data Sciences Core where she collaborates on a variety of basic science and clinical cancer studies. She also directs the Data Coordinating Center for the international, observational Hyperglycemia and Adverse Pregnancy Outcome (HAPO) Follow-Up Study and serves as the primary statistician for the HAPO Metabolomics and Integrated Omics Studies.

Education/Academic qualification

PhD, Harvard University

… → 2004

Research interests

  • Bioinformatics
  • Biostatistics
  • Computational Biology

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Grants

Northwestern Genomic Risk Assessment and Management Program

Aufox, S. A., Chisholm, R. L., Hoell, C., Kho, A. N., Luo, Y., McNally, E. M., Perera, M., Rasmussen-Torvik, L. J., Roy-Puckelwartz, M. J., Scherr, C. E. L., Scholtens, D. M., Smith, M. E., Starren, J. B., Walunas, T. L., Wehbe, F. & Gordon, A. S.

National Human Genome Research Institute

7/1/20 → 4/30/25

Project: Research project

Glycemic Profile of Pregnancy Consortium Biostatistics Research Center

Scholtens, D. M.

National Institute of Diabetes and Digestive and Kidney Diseases

9/20/19 → 7/31/24

Project: Research project

Central Laboratory Supplement for Glycemic Profile of Pregnancy Consortium Biostatistics Research Center

Scholtens, D. M.

National Institute of Diabetes and Digestive and Kidney Diseases

9/20/19 → 7/31/24

Project: Research project

    • The Kidney-Brain Connection: Role of Uremic Toxins

    Scholtens, D. M.

    University of Pennsylvania, National Institute of Diabetes and Digestive and Kidney Diseases

    9/20/19 → 7/31/20

    Project: Research project

    Aberrant DNA Methylation Underlying Adverse Prenatal Exposures and Increased Newborn and Childhood Adiposity

    Lowe Jr, W. L. & Scholtens, D. M.

    Ann & Robert H. Lurie Children's Hospital of Chicago, National Institute of Diabetes and Digestive and Kidney Diseases

    1/10/19 → 12/31/23

    Project: Research project

    • Research Output

    Bayesian estimation of genetic regulatory effects in high-throughput reporter assays

    Majoros, W. H., Kim, Y. S., Barrera, A., Li, F., Wang, X., Cunningham, S. J., Johnson, G. D., Guo, C., Lowe, W. L., Scholtens, D. M., Hayes, M. G., Reddy, T. E., Allen, A. S. & Berger, B., Jan 15 2020, In : Bioinformatics. 36, 2, p. 331-338 8 p.

    Research output: Contribution to journal › Article

    • Metabolomic and genetic associations with insulin resistance in pregnancy

    for the HAPO Study Cooperative Research Group, Jan 1 2020, (Accepted/In press) In : Diabetologia.

    Research output: Contribution to journal › Article

    • Ribosomal protein S11 influences glioma response to TOP2 poisons

    Awah, C. U., Chen, L., Bansal, M., Mahajan, A., Winter, J., Lad, M., Warnke, L., Gonzalez-Buendia, E., Park, C., Zhang, D., Feldstein, E., Yu, D., Zannikou, M., Balyasnikova, I. V., Martuscello, R., Konerman, S., Győrffy, B., Burdett, K. B., Scholtens, D. M., Stupp, R. & 3 others, Ahmed, A. U., Hsu, P. & Sonabend, A. M., Jul 2 2020, In : Oncogene. 39, 27, p. 5068-5081 14 p.

    Research output: Contribution to journal › Article

    • The Joint Associations of Maternal BMI and Glycemia with Childhood Adiposity

    Josefson, J. L., Catalano, P. M., Lowe, W. L., Scholtens, D. M., Kuang, A., Dyer, A. R., Lowe, L. P. & Metzger, B. E., Jul 1 2020, In : The Journal of clinical endocrinology and metabolism. 105, 7

    Research output: Contribution to journal › Article

    • Commentary: preclinical efficacy of immune-checkpoint monotherapy does not recapitulate corresponding biomarkers-based clinical predictions in glioblastoma by Garg et al. (2017)

    Zhai, L., Ladomersky, E., Lauing, K. L., Wu, M., Scholtens, D. M., Savoor, R., Zhang, B., Wu, J. D., Horbinski, C., Lukas, R. V., Binder, D. C. & Wainwright, D. A., Mar 4 2019, In : OncoImmunology. 8, 3, 1548242.

    Research output: Contribution to journal › Comment/debate