Grants per year
Personal profile
Research Interests
Dr. Denise Scholtens is interested in statistical problems arising from high-throughput omics data. She is Chief of the Division of Biostatistics and Associate Director for Biostatistics in the Robert H. Lurie Comprehensive Cancer Center Quantitative Data Sciences Core where she collaborates on a variety of basic science and clinical cancer studies. She also directs the Data Coordinating Center for the international, observational Hyperglycemia and Adverse Pregnancy Outcome (HAPO) Follow-Up Study and serves as the primary statistician for the HAPO Metabolomics and Integrated Omics Studies.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
PhD, Biostatistics, Harvard University
… → 2004
Research interests keywords
- Bioinformatics
- Biostatistics
- Computational Biology
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Hyperbaric Oxygen Therapy for Ulcerative Colitis Patients Hospitalized for Moderate to Severe Flares: A Phase 3 Multi-Center, Randomized, Double-Blind, Sham-Controlled Trial
Bonner, L. B., Dulai, P. S., Hanauer, S. B., Hirano, I., Scholtens, D. M., Sumagin, R. & Yang, G.
National Institute of Diabetes and Digestive and Kidney Diseases
3/15/23 → 2/28/28
Project: Research project
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Hyperglycemia and Adverse Pregnancy Outcome Study-
Lloyd-Jones, D. M., Allen, N. B., Bonner, L. B., Lowe Jr, W. L., Scholtens, D. M., Lowe Jr, W. L. & Metzger, B. E.
Ann & Robert H. Lurie Children’s Hospital of Chicago, National Heart, Lung, and Blood Institute
3/1/23 → 2/29/28
Project: Research project
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Successful Clinical Response In Pneumonia Therapy (SCRIPT) Systems Biology Center
Wunderink, R. G., Wunderink, R. G., Abdala-Valencia, H., Budinger, G. S., Budinger, G. S., Etemadi, M., Hartmann, E. M., Hultquist, J. F., Lorenzo Redondo, R., Luo, Y., Misharin, A., Morales-Nebreda, L., Ozer, E. A., Pickens, C. I., Qi, C., Scholtens, D. M., Singer, B., Stoeger, T., Swaminathan, S., Walter, J. M., Wunderink, R. G., Amaral, L. A. N., Budinger, G. S., Hartmann, E. M., Hauser, A. R., Misharin, A., Ozer, E. A., Pickens, C. I., Qi, C., Singer, B., Starren, J., Stoeger, T., Walter, J. M. & Wunderink, R. G.
National Institute of Allergy and Infectious Diseases
1/1/23 → 12/31/27
Project: Research project
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Glycemic Observation Using A1C for Gestational Diabetes Diagnosis
Scholtens, D. M. & Scholtens, D. M.
Massachusetts General Hospital, National Institute of Child Health and Human Development
6/15/22 → 5/31/27
Project: Research project
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Association of a large-for-gestational-age infant and maternal prediabetes mellitus and diabetes mellitus 10 to 14 years after delivery in the Hyperglycemia and Adverse Pregnancy Outcome Follow-up Study
Venkatesh, K. K., Grobman, W. A., Wu, J., Catalano, P., Landon, M., Scholtens, D., Lowe, W. L. & Khan, S. S., Jun 2023, In: American journal of obstetrics and gynecology. 228, 6, p. 756-758.e3Research output: Contribution to journal › Letter › peer-review
Open Access1 Scopus citations -
Association of Maternal Metabolites and Metabolite Networks with Newborn Outcomes in a Multi-Ancestry Cohort
Gleason, B., Kuang, A., Bain, J. R., Muehlbauer, M. J., Ilkayeva, O. R., Scholtens, D. M. & Lowe, W. L., Apr 2023, In: Metabolites. 13, 4, 505.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Author Correction: Genetic effects on the timing of parturition and links to fetal birth weight (Nature Genetics, (2023), 55, 4, (559-567), 10.1038/s41588-023-01343-9)
Early Growth Genetics Consortium, Estonian Biobank Research Team & Danish Blood Donor Study Genomic Consortium, Jul 2023, In: Nature Genetics. 55, 7, p. 1250 1 p.Research output: Contribution to journal › Comment/debate › peer-review
Open Access -
Determining venous thromboembolism risk in patients with adult-type diffuse glioma
Burdett, K. B., Unruh, D., Drumm, M., Steffens, A., Lamano, J., Judkins, J., Schwartz, M., Javier, R., Amidei, C., Lipp, E. S., Peters, K. B., Lai, A., Eldred, B. S. C., Heimberger, A. B., McCortney, K., Scholtens, D. M. & Horbinski, C., Mar 16 2023, In: Blood. 141, 11, p. 1322-1336 15 p.Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
Docetaxel targets aggressive methylation profiles and serves as a radiosensitizer in high-risk meningiomas
Youngblood, M. W., Tran, A. N., Wang, W., An, S., Scholtens, D., Zhang, L., O'Shea, K., Pokorny, J. L., Magill, S. T., Sachdev, S., Lukas, R. V., Ahmed, A., Unruh, D., Walshon, J., McCortney, K., Wang, Y., Baran, A., Sahm, F., Aldape, K., Chandler, J. P., & 3 others, Mar 14 2023, In: Neuro-oncology. 25, 3, p. 508-519 12 p.Research output: Contribution to journal › Article › peer-review
2 Scopus citations
Datasets
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Synuclein-γ (SNCG) expression in ovarian cancer is associated with high-risk clinicopathologic disease
Strohl, A. (Creator), Mori, K. (Creator), Akers, S. (Creator), Bshara, W. (Contributor), Buttin, B. (Creator), Frederick, P. J. (Creator), Helenowski, I. B. (Creator), Morrison, C. D. (Creator), Odunsi, K. (Contributor), Schink, J. C. (Creator), Scholtens, D. M. (Creator), Wei, J. (Creator), Kim, J. J. (Contributor), Wiam, B. (Contributor) & Kunle, O. (Contributor), figshare, 2016
DOI: 10.6084/m9.figshare.c.3621737.v1, https://figshare.com/collections/Synuclein-_SNCG_expression_in_ovarian_cancer_is_associated_with_high-risk_clinicopathologic_disease/3621737/1
Dataset
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Additional file 5: Table S2. of Transversions have larger regulatory effects than transitions
Guo, C. (Creator), McDowell, I. C. (Creator), Nodzenski, M. (Creator), Scholtens, D. M. (Creator), Allen, A. S. (Creator), Lowe Jr, W. L. (Creator), Reddy, T. E. (Creator) & Scholtens, D. (Creator), figshare, 2017
DOI: 10.6084/m9.figshare.c.3784286_d5, https://springernature.figshare.com/articles/dataset/Additional_file_5_Table_S2_of_Transversions_have_larger_regulatory_effects_than_transitions/5027114
Dataset
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Research data supporting "Associations between a Fetal Imprinted Gene Allele Score and Late Pregnancy Maternal Glucose Concentrations"
Petry, C. J. (Contributor), Mooslehner, K. (Contributor), Prentice, P. (Contributor), Hayes, M. G. (Contributor), Nodzenski, M. (Contributor), Scholtens, D. M. (Contributor), Hughes, I. A. (Contributor), Acerini, C. L. (Contributor), Ong, K. K. (Contributor), Lowe Jr, W. L. (Contributor) & Dunger, D. B. (Contributor), Apollo Cambridge, Mar 28 2017
DOI: 10.17863/cam.8579, https://www.repository.cam.ac.uk/1810/263266
Dataset
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Transversions have larger regulatory effects than transitions
Guo, C. (Creator), McDowell, I. C. (Creator), Nodzenski, M. (Creator), Scholtens, D. M. (Creator), Allen, A. S. (Creator), Lowe Jr, W. L. (Creator), Reddy, T. E. (Creator) & Scholtens, D. (Creator), figshare, 2017
DOI: 10.6084/m9.figshare.c.3784286.v1, https://figshare.com/collections/Transversions_have_larger_regulatory_effects_than_transitions/3784286/1
Dataset
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Additional file 3: of Mixture model normalization for non-targeted gas chromatography/mass spectrometry metabolomics data
Reisetter, A. C. (Creator), Muehlbauer, M. J. (Creator), Bain, J. R. (Creator), Nodzenski, M. (Creator), Stevens, R. D. (Creator), Ilkayeva, O. (Creator), Metzger, B. E. (Creator), Newgard, C. B. (Creator), Lowe Jr, W. L. (Creator), Scholtens, D. M. (Creator), Bain, J. (Creator), Stevens, R. (Creator), Metzger, B. (Creator) & Scholtens, D. (Creator), figshare, 2017
DOI: 10.6084/m9.figshare.c.3681940_d4, https://springernature.figshare.com/articles/dataset/Additional_file_3_of_Mixture_model_normalization_for_non-targeted_gas_chromatography_mass_spectrometry_metabolomics_data/4615867
Dataset