Grants per year
Personal profile
Research Interests
Professor Joester’s research group is driven by the desire to understand not only the design, i.e. the structure and functional organization of biominerals, but also their integrated synthesis. On a cellular level, these two, design and its execution, are inextricably linked. Their highly interdisciplinary approach reflects this complexity and rests on both the engineering of biomaterials synthesis in cell culture and the biologically inspired synthetic (re)construction of artificial mineralizing systems. In this way, they hope to find ways to create new materials of functional and architectural sophistication that rival that of biominerals.
Following their recent discovery of a highly soluble Mg-rich intergranular film in vertebrate tooth enamel, they embarked on an investigation into its role in tooth decay and bioinspired approaches to prevent caries. Research in the Joester group therefore includes (bio)synthesis, functional properties, and degradation of biominerals.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Chemistry, PhD, Swiss Federal Institute of Technology Zurich
Chemistry, MSc, Swiss Federal Institute of Technology Zurich
Chemistry and Pharmacy, BA, University of Tübingen
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Collaborations and top research areas from the last five years
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Bioengineering Single Crystal Growth
Joester, D. (PD/PI) & Alvares, K. (Co-PD/PI)
7/15/24 → 6/30/28
Project: Research project
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Biofilm Elimination and Caries Prevention using Multifunctional Nanocatalysts
Joester, D. (PD/PI) & Joester, D. (PD/PI)
University of Pennsylvania, National Institute of Dental and Craniofacial Research
9/1/23 → 8/31/25
Project: Research project
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Enamel atlas: systems-level amelogenesis tools at multiple scales
Joester, D. (PD/PI), Joester, D. (PD/PI), Alvares, K. (Co-Investigator), Alvares, K. (Co-Investigator), Stock, S. R. (Co-Investigator) & Stock, S. R. (Co-Investigator)
University of California, San Francisco, National Institute of Dental and Craniofacial Research
8/1/21 → 7/31/24
Project: Research project
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Unlocking the Cryo-Domain: Bio-Cryo-Tomography from Micro to Atomic Scale
Joester, D. (PD/PI)
2/1/21 → 3/31/23
Project: Research project
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SR SEQUESTRATION AND MINERALIZATION IN ACANTHAREA
Joester, D. (PD/PI), Joester, D. (PD/PI), Alvares, K. (Co-PD/PI) & Alvares, K. (Co-PD/PI)
5/20/20 → 11/19/24
Project: Research project
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Characterization of mineralized tissues by atom probe tomography
Zhao, X. & Joester, D., Jan 28 2025, In: Journal of Materials Research. 40, 2, p. 141-152 12 p.Research output: Contribution to journal › Review article › peer-review
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Adapting neural networks for rapid segmentation of mineralized tissues in mouse jaws
Cooley, V., Suwandi, E., Stock, S. R. & Joester, D., 2024, Developments in X-Ray Tomography XV. Muller, B. & Wang, G. (eds.). SPIE, 131520V. (Proceedings of SPIE - The International Society for Optical Engineering; vol. 13152).Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
1 Scopus citations -
Adult dental epithelial stem cell-derived organoids deposit hydroxylapatite biomineral
Kim, H. Y., Cooley, V., Kim, E. J., Li, S., Lee, J. M., Sheyfer, D., Liu, W., Klein, O. D., Joester, D. & Jung, H. S., Dec 2023, In: International Journal of Oral Science. 15, 1, 55.Research output: Contribution to journal › Article › peer-review
Open Access9 Scopus citations -
Iron oxide nanozymes stabilize stannous fluoride for targeted biofilm killing and synergistic oral disease prevention
Huang, Y., Liu, Y., Pandey, N. K., Shah, S., Simon-Soro, A., Hsu, J. C., Ren, Z., Xiang, Z., Kim, D., Ito, T., Oh, M. J., Buckley, C., Alawi, F., Li, Y., Smeets, P. J. M., Boyer, S., Zhao, X., Joester, D., Zero, D. T. & Cormode, D. P. & 1 others, , Dec 2023, In: Nature communications. 14, 1, 6087.Research output: Contribution to journal › Article › peer-review
29 Scopus citations -
Multi-scale characterization of Developmental Defects of Enamel and their clinical significance for diagnosis and treatment
Houari, S., DeRocher, K., Thuy, T. T., Coradin, T., Srot, V., van Aken, P. A., Lecoq, H., Sauvage, T., Balan, E., Aufort, J., Calemme, M., Roubier, N., Bosco, J., Jedeon, K., Berdal, A., Joester, D. & Babajko, S., Oct 1 2023, In: Acta Biomaterialia. 169, p. 155-167 13 p.Research output: Contribution to journal › Article › peer-review
Open Access11 Scopus citations
Datasets
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CCDC 245959: Experimental Crystal Structure Determination
Joester, D. (Creator), Gramlich, V. (Creator) & Diederich, F. (Creator), Cambridge Crystallographic Data Centre, 2005
DOI: 10.5517/cc87y5l, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/cc87y5l&sid=DataCite
Dataset
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CCDC 245960: Experimental Crystal Structure Determination
Joester, D. (Creator), Gramlich, V. (Creator) & Diederich, F. (Creator), Cambridge Crystallographic Data Centre, 2005
DOI: 10.5517/cc87y6m, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/cc87y6m&sid=DataCite
Dataset