Deyu Fang

  • 4092 Citations
19992023
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Personal profile

Education/Academic qualification

PhD, Gunma University School of Medicine

… → 2000

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  • 9 Similar Profiles
T-Lymphocytes Medicine & Life Sciences
Ubiquitin-Protein Ligases Medicine & Life Sciences
T-cells Chemical Compounds
Ubiquitination Medicine & Life Sciences
Ubiquitin Medicine & Life Sciences
Sirtuin 1 Medicine & Life Sciences
Chemical activation Chemical Compounds
Histone Deacetylase 1 Medicine & Life Sciences

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Grants 2009 2023

Ubiquitin
Peptide Hydrolases
Immunotherapy
Therapeutics
Immunity
Immunity
Neoplasms
Regulatory T-Lymphocytes
Immunosuppressive Agents
Tumor Microenvironment
Immunity
Neoplasms
Tumor Microenvironment
Myeloid Cells
Cell Differentiation
Arthritis
Rheumatoid Arthritis
Macrophages
Dendritic Cells
Autoantibodies
Histone Code
Antipsychotic Agents
Histone Deacetylase Inhibitors
Drug-Related Side Effects and Adverse Reactions
Epigenomics

Research Output 1999 2019

  • 4092 Citations
  • 89 Article
  • 8 Review article
  • 1 Editorial

A novel recombinant peptide INSR-IgG4Fc (Yiminsu) restores insulin sensitivity in experimental insulin resistance models

Wang, J., Shi, Z., Zou, T., Zou, M. X., Yang, H. X., Zhang, C. P., Xiang, D. B., Lin, L. M., Liu, H. Y., Fang, D. & Liao, D. F., Jan 1 2019, In : Biomedicine and Pharmacotherapy. 109, p. 1276-1286 11 p.

Research output: Contribution to journalArticle

Type 2 Diabetes Mellitus
Insulin Resistance
Palmitic Acid
Insulin
High Fat Diet

ER-associated ubiquitin ligase HRD1 programs liver metabolism by targeting multiple metabolic enzymes

Wei, J., Yuan, Y., Chen, L., Xu, Y., Zhang, Y., Wang, Y., Yang, Y., Bien, C., Diebold, L., Yang, Y., Gao, B., Jin, C., Melo-Cardenas, J., Chandel, N., Zhang, D. D., Pan, H., Zhang, K., Wang, J., He, F. & Fang, D., Dec 1 2018, In : Nature communications. 9, 1, 3659.

Research output: Contribution to journalArticle

Hydroxymethylglutaryl CoA Reductases
metabolism
Ligases
Ubiquitin
liver
1 Citations

Farnesoid X receptor signaling activates the hepatic X-box binding protein 1 pathway in vitro and in mice

Liu, X., Guo, G. L., Kong, B., Hilburn, D. B., Hubchak, S. C., Park, S., LeCuyer, B., Hsieh, A., Wang, L., Fang, D. & Green, R., Jul 1 2018, In : Hepatology. 68, 1, p. 304-316 13 p.

Research output: Contribution to journalArticle

Inositol
Bile Acids and Salts
Liver
Cholestyramine Resin
Unfolded Protein Response
1 Citations

HRD1-ERAD controls production of the hepatokine FGF21 through CREBH polyubiquitination

Wei, J., Chen, L., Li, F., Yuan, Y., Wang, Y., Xia, W., Zhang, Y., Xu, Y., Yang, Z., Gao, B., Jin, C., Melo-Cardenas, J., Green, R., Pan, H., Wang, J., He, F., Zhang, K. & Fang, D., Nov 15 2018, In : EMBO Journal. 37, 22, e98942.

Research output: Contribution to journalArticle

Endoplasmic Reticulum-Associated Degradation
Production control
Proteolysis
Degradation
Liver
2 Citations

IRE1 prevents hepatic steatosis by processing and promoting the degradation of select microRNAs

Wang, J. M., Qiu, Y., Yang, Z., Kim, H., Qian, Q., Sun, Q., Zhang, C., Yin, L., Fang, D., Back, S. H., Kaufman, R. J., Yang, L. & Zhang, K., May 15 2018, In : Science Signaling. 11, 530, eaao4617.

Research output: Contribution to journalArticle

Inositol
MicroRNAs
Liver
Enzymes
Endoribonucleases