Deyu Fang

  • 4286 Citations
19992023
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Personal profile

Education/Academic qualification

PhD, Gunma University School of Medicine

… → 2000

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  • 10 Similar Profiles
Ubiquitin-Protein Ligases Medicine & Life Sciences
T-Lymphocytes Medicine & Life Sciences
T-cells Chemical Compounds
Ubiquitination Medicine & Life Sciences
Ubiquitin Medicine & Life Sciences
Sirtuin 1 Medicine & Life Sciences
Chemical activation Chemical Compounds
Histone Deacetylase 1 Medicine & Life Sciences

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Grants 2009 2023

Immunity
Neoplasms
Regulatory T-Lymphocytes
Immunosuppressive Agents
Tumor Microenvironment
Ubiquitin
Peptide Hydrolases
Immunotherapy
Therapeutics
Immunity
Immunity
Neoplasms
Tumor Microenvironment
Myeloid Cells
Cell Differentiation
Arthritis
Rheumatoid Arthritis
Macrophages
Dendritic Cells
Autoantibodies
Histone Code
Antipsychotic Agents
Histone Deacetylase Inhibitors
Drug-Related Side Effects and Adverse Reactions
Epigenomics

Research Output 1999 2019

  • 4286 Citations
  • 91 Article
  • 8 Review article
  • 1 Editorial

A novel recombinant peptide INSR-IgG4Fc (Yiminsu) restores insulin sensitivity in experimental insulin resistance models

Wang, J., Shi, Z., Zou, T., Zou, M. X., Yang, H. X., Zhang, C. P., Xiang, D. B., Lin, L. M., Liu, H. Y., Fang, D. & Liao, D. F., Jan 1 2019, In : Biomedicine and Pharmacotherapy. 109, p. 1276-1286 11 p.

Research output: Contribution to journalArticle

Insulin Resistance
Palmitic Acid
Insulin
High Fat Diet
Peptides

CD73 expression on effector T cells sustained by TGF-β facilitates tumor resistance to anti-4-1BB/CD137 therapy

Chen, S., Fan, J., Zhang, M., Qin, L., Dominguez, D., Long, A., Wang, G., Ma, R., Li, H., Zhang, Y., Fang, D., Sosman, J. A. & Zhang, B., Dec 1 2019, In : Nature communications. 10, 1, 150.

Research output: Contribution to journalArticle

effectors
T-cells
Tumors
therapy
tumors

The E3 ligase Hrd1 stabilizes Tregs by antagonizing inflammatory cytokine-induced ER stress response

Xu, Y., Melo-Cardenas, J., Zhang, Y., Gau, I., Wei, J., Montauti, E., Zhang, Y., Gao, B., Jin, H., Sun, Z., Lee, S. M. & Fang, D., Mar 7 2019, In : JCI insight. 4, 5

Research output: Contribution to journalArticle

Endoribonucleases
Ubiquitin-Protein Ligases
p38 Mitogen-Activated Protein Kinases
Small Intestine
Weight Loss

ER-associated ubiquitin ligase HRD1 programs liver metabolism by targeting multiple metabolic enzymes

Wei, J., Yuan, Y., Chen, L., Xu, Y., Zhang, Y., Wang, Y., Yang, Y., Bien, C., Diebold, L., Yang, Y., Gao, B., Jin, C., Melo-Cardenas, J., Chandel, N., Zhang, D. D., Pan, H., Zhang, K., Wang, J., He, F. & Fang, D., Dec 1 2018, In : Nature communications. 9, 1, 3659.

Research output: Contribution to journalArticle

Hydroxymethylglutaryl CoA Reductases
metabolism
Ligases
Ubiquitin
liver
2 Citations (Scopus)

Farnesoid X receptor signaling activates the hepatic X-box binding protein 1 pathway in vitro and in mice

Liu, X., Guo, G. L., Kong, B., Hilburn, D. B., Hubchak, S. C., Park, S., LeCuyer, B., Hsieh, A., Wang, L., Fang, D. & Green, R., Jul 1 2018, In : Hepatology. 68, 1, p. 304-316 13 p.

Research output: Contribution to journalArticle

Inositol
Bile Acids and Salts
Liver
Cholestyramine Resin
Unfolded Protein Response