• 885 Citations
20042024

Research output per year

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Research Output

  • 885 Citations
  • 14 Article
  • 5 Review article
  • 2 Comment/debate
  • 2 Short survey
2019

Computational model demonstrates that Ndc80-associated proteins strengthen kinetochore-microtubule attachments in metaphase

Campbell, S., Amin, M. A., Varma, D. & Bidone, T. C., Nov 1 2019, In : Cytoskeleton. 76, 11-12, p. 549-561 13 p.

Research output: Contribution to journalArticle

2 Scopus citations

Mapping the kinetochore MAP functions required for stabilizing microtubule attachments to chromosomes during metaphase

Amin, M. A., Agarwal, S. & Varma, D., Jun 1 2019, In : Cytoskeleton. 76, 6, p. 398-412 15 p.

Research output: Contribution to journalReview article

1 Scopus citations
2018

Antagonism between the dynein and Ndc80 complexes at kinetochores controls the stability of kinetochore-microtubule attachments during mitosis

Amin, M. A., McKenney, R. J. & Varma, D., Jan 1 2018, In : Journal of Biological Chemistry. 293, 16, p. 5755-5765 11 p.

Research output: Contribution to journalArticle

2 Scopus citations

Cdt1 stabilizes kinetochore-microtubule attachments via an Aurora B kinase-dependent mechanism

Agarwal, S., Smith, K. P., Zhou, Y., Suzuki, A., McKenney, R. J. & Varma, D., Oct 1 2018, In : The Journal of cell biology. 217, 10, p. 3446-3463 18 p.

Research output: Contribution to journalArticle

Open Access
5 Scopus citations

Cell Division: The Unattached Kinetochore Wears an Expansive RZZ Coat

Suzuki, A. & Varma, D., Nov 5 2018, In : Current Biology. 28, 21, p. R1250-R1252

Research output: Contribution to journalShort survey

2017
1 Scopus citations

Targeting mitotic pathways for endocrine-related cancer therapeutics

Agarwal, S. & Varma, D., Sep 1 2017, In : Endocrine-related cancer. 24, 9, p. T65-T82

Research output: Contribution to journalReview article

2 Scopus citations
2015

CDK1-dependent inhibition of the E3 ubiquitin ligase CRL4CDT2 ensures robust transition from S phase to mitosis

Rizzardi, L. F., Coleman, K. E., Varma, D., Matson, J. P., Oh, S. & Cook, J. G., Jan 2 2015, In : Journal of Biological Chemistry. 290, 1, p. 556-567 12 p.

Research output: Contribution to journalArticle

21 Scopus citations

Cell division: Molecular pathways for KMN kinetochore recruitment

Afreen, S. & Varma, D., Apr 20 2015, In : Current Biology. 25, 8, p. R332-R335 11848.

Research output: Contribution to journalShort survey

1 Scopus citations

Sequential replication-coupled destruction at G1/S ensures genome stability

Coleman, K. E., Grant, G. D., Haggerty, R. A., Brantley, K., Shibata, E., Workman, B. D., Dutta, A., Varma, D., Purvis, J. E. & Cook, J. G., Aug 15 2015, In : Genes and Development. 29, 16, p. 1734-1746 13 p.

Research output: Contribution to journalArticle

25 Scopus citations

The RZZ complex requires the N-terminus of KNL1 to mediate optimal Mad1 kinetochore localization in human cells

Calda, G. V., Lynch, T. R., Anderson, R., Afreen, S., Varma, D. & De Luca, J. G., Nov 2015, In : Open Biology. 5, 11, 150160.

Research output: Contribution to journalArticle

26 Scopus citations
2014

How the SAC gets the axe: Integrating kinetochore microtubule attachments with spindle assembly checkpoint signaling

Agarwal, S. & Varma, D., Aug 3 2014, In : BioArchitecture. 5, 1-2, p. 1-12 12 p.

Research output: Contribution to journalArticle

1 Scopus citations
2013

Spindle assembly checkpoint proteins are positioned close to core microtubule attachment sites at kinetochores

Varma, D., Wan, X., Cheerambathur, D., Gassmann, R., Suzuki, A., Lawrimore, J., Desai, A. & Salmon, E. D., Sep 20 2013, In : Journal of Cell Biology. 202, 5, p. 735-746 12 p.

Research output: Contribution to journalArticle

41 Scopus citations
2012

Recruitment of the human Cdt1 replication licensing protein by the loop domain of Hec1 is required for stable kinetochore-microtubule attachment

Varma, D., Chandrasekaran, S., Sundin, L. J. R., Reidy, K. T., Wan, X., Chasse, D. A. D., Nevis, K. R., Deluca, J. G., Salmon, E. D. & Cook, J. G., Jun 1 2012, In : Nature Cell Biology. 14, 6, p. 593-603 11 p.

Research output: Contribution to journalArticle

51 Scopus citations

The KMN protein network - Chief conductors of the kinetochore orchestra

Varma, D. & Salmon, E. D., Dec 15 2012, In : Journal of cell science. 125, 24, p. 5927-5936 10 p.

Research output: Contribution to journalComment/debate

64 Scopus citations
2010

Development and application of in vivo molecular traps reveals that dynein light chain occupancy differentially affects dynein-mediated processes

Varma, D., Dawn, A., Ghosh-Roy, A., Weil, S. J., Ori-McKenney, K. M., Zhao, Y., Keen, J., Vallee, R. B. & Williams, J. C., Feb 23 2010, In : Proceedings of the National Academy of Sciences of the United States of America. 107, 8, p. 3493-3498 6 p.

Research output: Contribution to journalArticle

20 Scopus citations

Emerging functions of force-producing kinetochore motors

Mao, Y., Varma, D. & Vallee, R., Feb 15 2010, In : Cell Cycle. 9, 4, p. 715-719 5 p.

Research output: Contribution to journalReview article

15 Scopus citations

Removal of Spindly from microtubule-attached kinetochores controls spindle checkpoint silencing in human cells

Gassmann, R., Holland, A. J., Varma, D., Wan, X., Çivril, F., Cleveland, D. W., Oegema, K., Salmon, E. D. & Desai, A., May 1 2010, In : Genes and Development. 24, 9, p. 957-971 15 p.

Research output: Contribution to journalArticle

114 Scopus citations
2008

Direct role of dynein motor in stable kinetochore-microtubule attachment, orientation, and alignment

Varma, D., Monzo, P., Stehman, S. A. & Vallee, R. B., Sep 22 2008, In : Journal of Cell Biology. 182, 6, p. 1045-1054 10 p.

Research output: Contribution to journalArticle

74 Scopus citations
2006

Role of the kinetochore/cell cycle checkpoint protein ZW10 in interphase cytoplasmic dynein function

Varma, D., Dujardin, D. L., Stehman, S. A. & Vallee, R. B., Feb 27 2006, In : Journal of Cell Biology. 172, 5, p. 655-662 8 p.

Research output: Contribution to journalArticle

51 Scopus citations

ZW10 function in mitotic checkpoint control, dynein targeting and membrane trafficking: Is dynein the unifying theme?

Vallee, R. B., Varma, D. & Dujardin, D. L., Nov 1 2006, In : Cell Cycle. 5, 21, p. 2447-2451 5 p.

Research output: Contribution to journalReview article

34 Scopus citations
2004

Dynein: An Ancient Motor Protein Involved in Multiple Modes of Transport

Vallee, R. B., Williams, J. C., Varma, D. & Barnhart, L. E., Feb 5 2004, In : Journal of Neurobiology. 58, 2, p. 189-200 12 p.

Research output: Contribution to journalReview article

334 Scopus citations