Research Output per year
Personal profile
Certifications and Licenses
| 2000 | Residency, Massachusetts General Hospital and Brigham and Women’s Hospital, Harvard Medical School |
| 2002 | Fellowship, Massachusetts General Hospital and Brigham and Women’s Hospital, Harvard Medical School |
| Neurology |
Keywords
- Gene Regulation
- Neurology
- Neuroscience
- Neurogenetics
- Alzheimer's Disease
- Aging
- Movement Disorders
- Parkinson’s disease
Fingerprint Fingerprint is based on mining the text of the persons scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.
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Network
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Research Output 1993 2017
Dopamine oxidation mediates a human-specific cascade of mitochondrial and lysosomal dysfunction in Parkinson's disease.
Burbulla, L. F., Song, P., Mazzulli, J. R., Zampese, E., Wong, Y. C., Jeon, S., Santos, D. P., Blanz, J., Obermaier, C., Strojny, C., Savas, J., Kiskinis, E., Zhuang, X., Kruger, R., Surmeier, J. D. & Krainc, D. 2017 In : Science.Research output: Contribution to journal › Article
Lysosomal Proteins as a Therapeutic Target in Neurodegeneration
Mc Donald, J. M. & Krainc, D. Jan 14 2017 In : Annual Review of Medicine. 68, p. 445-458 14 p.Research output: Contribution to journal › Review article
Lysosomal Storage Diseases
Neurodegenerative Diseases
Proteins
Supravalvular Aortic Stenosis
Submandibular Gland
3
Citations
The Parkinson's disease-linked protein TMEM230 is required for Rab8a-mediated secretory vesicle trafficking and retromer trafficking
Kim, M. J., Deng, H. X., Wong, Y. C., Siddique, T. & Krainc, D. Feb 15 2017 In : Human Molecular Genetics. 26, 4, p. 729-741 13 p.Research output: Contribution to journal › Article
Secretory Vesicles
Parkinson Disease
Proteins
Genes
Autophagy
4
Citations
α-synuclein toxicity in neurodegeneration: Mechanism and therapeutic strategies
Wong, Y. C. & Krainc, D. Feb 7 2017 In : Nature Medicine. 23, 2, p. 1-13 13 p.Research output: Contribution to journal › Review article
alpha-Synuclein
Supravalvular Aortic Stenosis
Parkinson Disease
Acrodermatitis
Multiple System Atrophy
14
Citations
Activation of β-glucocerebrosidase reduces pathological α-synuclein and restores lysosomal function in Parkinson’s patient midbrain neurons
Mazzulli, J. R., Zunke, F., Tsunemi, T., Toker, N. J., Jeon, S., Burbulla, L. F., Patnaik, S., Sidransky, E., Marugan, J. J., Sue, C. M. & Krainc, D. Jul 20 2016 In : Journal of Neuroscience. 36, 29, p. 7693-7706 14 p.Research output: Contribution to journal › Article
Glucosylceramidase
alpha-Synuclein
Mesencephalon
Neurons
Parkinson Disease