Personal profile

Certifications and Licenses

2000Residency, Massachusetts General Hospital and Brigham and Women’s Hospital, Harvard Medical School
2002Fellowship, Massachusetts General Hospital and Brigham and Women’s Hospital, Harvard Medical School
Neurology

Keywords

  • Gene Regulation
  • Neurology
  • Neuroscience
  • Neurogenetics
  • Alzheimer's Disease
  • Aging
  • Movement Disorders
  • Parkinson’s disease

Fingerprint Fingerprint is based on mining the text of the person's scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

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Research Output 1993 2017

1 Citations

Analysis of blood-based gene expression in idiopathic Parkinson disease

Shamir, R. , Klein, C. , Amar, D. , Vollstedt, E. J. , Bonin, M. , Usenovic, M. , Wong, Y. C. , Maver, A. , Poths, S. , Safer, H. , Corvol, J. C. , Lesage, S. , Lavi, O. , Deuschl, G. , Kuhlenbaeumer, G. , Pawlack, H. , Ulitsky, I. , Kasten, M. , Riess, O. , Brice, A. & 2 others Peterlin, B. & Krainc, D. Oct 17 2017 In : Neurology. 89, 16, p. 1676-1683 8 p.

Research output: Research - peer-reviewArticle

Parkinson Disease
Gene Expression
Genes
Area Under Curve
Down-Regulation
1 Citations

A PDE10A de novo mutation causes childhood-onset chorea with diurnal fluctuations

Esposito, S., Carecchio, M., Tonduti, D., Saletti, V., Panteghini, C., Chiapparini, L., Zorzi, G., Pantaleoni, C., Garavaglia, B., Krainc, D., Lubbe, S. J., Nardocci, N. & Mencacci, N. E. Nov 1 2017 In : Movement Disorders. 32, 11, p. 1646-1647 2 p.

Research output: Research - peer-reviewLetter

Dopamine oxidation mediates a human-specific cascade of mitochondrial and lysosomal dysfunction in Parkinson's disease.

Burbulla, L. F., Song, P., Mazzulli, J. R., Zampese, E., Wong, Y. C., Jeon, S., Santos, D. P., Blanz, J., Obermaier, C., Strojny, C., Savas, J., Kiskinis, E., Zhuang, X., Kruger, R., Surmeier, J. D. & Krainc, D. 2017 In : Science.

Research output: ResearchArticle

8 Citations

Dopamine oxidation mediates mitochondrial and lysosomal dysfunction in Parkinson’s disease

Burbulla, L. F., Song, P., Mazzulli, J. R., Zampese, E., Wong, Y. C., Jeon, S., Santos, D. P., Blanz, J., Obermaier, C. D., Strojny, C., Savas, J. N., Kiskinis, E., Zhuang, X., Krüger, R., Surmeier, D. J. & Krainc, D. Sep 22 2017 In : Science. 357, 6357, p. 1255-1261 7 p.

Research output: Research - peer-reviewArticle

Parkinson Disease
Dopamine
Neurons
Synucleins
Glucosylceramidase

Lysosomal integral membrane protein-2 as a phospholipid receptor revealed by biophysical and cellular studies

Conrad, K. S., Cheng, T. W., Ysselstein, D., Heybrock, S., Hoth, L. R., Chrunyk, B. A., Am Ende, C. W., Krainc, D., Schwake, M., Saftig, P., Liu, S., Qiu, X. & Ehlers, M. D. Dec 1 2017 In : Nature Communications. 8, 1, 1908

Research output: Research - peer-reviewArticle

Lysosome-Associated Membrane Glycoproteins
Glucosylceramidase
Phosphatidylserines
Phosphatidylcholines
Phospholipids