Calculated based on number of publications stored in Pure and citations from Scopus
Calculated based on number of publications stored in Pure and citations from Scopus
Calculated based on number of publications stored in Pure and citations from Scopus
1988 …2024

Research activity per year

Search results

  • 2024

    A GNAI1 Pathogenic Variant in a Case with GNAO1-Isolated Dystonia: A Modifier of Disease Severity?

    Monje, M. H. G., Blackburn, J. S., Kinsley, L., Krainc, D. & Mencacci, N. E., 2024, (Accepted/In press) In: Movement Disorders.

    Research output: Contribution to journalLetterpeer-review

    Open Access
  • Alterations in Blood Methylome as Potential Epigenetic Biomarker in Sporadic Parkinson's Disease

    Gonzalez-Latapi, P., Bustos, B., Dong, S., Lubbe, S., Simuni, T. & Krainc, D., 2024, (Accepted/In press) In: Annals of neurology.

    Research output: Contribution to journalArticlepeer-review

    Open Access
  • Cell biology of Parkinson's disease: Mechanisms of synaptic, lysosomal, and mitochondrial dysfunction

    Brooker, S. M., Naylor, G. E. & Krainc, D., Apr 2024, In: Current opinion in neurobiology. 85, 102841.

    Research output: Contribution to journalReview articlepeer-review

    3 Scopus citations
  • De novo FRMD5 Missense Variants in Patients with Childhood-Onset Ataxia, Prominent Nystagmus, and Seizures

    Keller Sarmiento, I. J., Bustos, B. I., Blackburn, J., Hac, N. E. F., Ruzhnikov, M., Monroe, M., Levy, R. J., Kinsley, L., Li, M., Silani, V., Lubbe, S. J., Krainc, D. & Mencacci, N. E., 2024, (Accepted/In press) In: Movement Disorders.

    Research output: Contribution to journalArticlepeer-review

    Open Access
  • Fostering Academia-Industry Partnerships to Facilitate Therapeutic Discoveries in Neurology: The Role of ANA as a Catalyst

    Ross, M. E., Krainc, D., Guo, M., Mouradian, M. M. & Ratan, R. R., May 2024, In: Annals of neurology. 95, 5, p. 825-826 2 p.

    Research output: Contribution to journalComment/debatepeer-review

  • Inhibition of cysteine protease cathepsin L increases the level and activity of lysosomal glucocerebrosidase

    Kim, M. J., Kim, S., Reinheckel, T. & Krainc, D., 2024, In: JCI Insight. 9, 3, e169594.

    Research output: Contribution to journalArticlepeer-review

    Open Access
  • Key genes and convergent pathogenic mechanisms in Parkinson disease

    Coukos, R. & Krainc, D., 2024, (Accepted/In press) In: Nature Reviews Neuroscience.

    Research output: Contribution to journalReview articlepeer-review

  • Open Access
  • VPS13C regulates phospho-Rab10-mediated lysosomal function in human dopaminergic neurons

    Schrӧder, L. F., Peng, W., Gao, G., Wong, C. H. Y., Schwake, M. & Krainc, D., May 6 2024, In: The Journal of cell biology. 223, 5

    Research output: Contribution to journalArticlepeer-review

    Open Access
    1 Scopus citations
  • 2023

    Expanding the spectrum of KCNJ6-related disorders: Milder phenotype with pathological startle responses

    van Midden, V. M., Kinsley, L., Fraint, A., Krainc, D. & Mencacci, N. E., Jan 2023, In: Clinical genetics. 103, 1, p. 103-108 6 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    1 Scopus citations
  • Extracellular transportation of α-synuclein by HLA class II molecules

    Ozono, T., Kimura, Y., Suenaga, T., Beck, G., Jinno, J., Aguirre, C., Ikenaka, K., Krainc, D., Mochizuki, H. & Arase, H., Feb 12 2023, In: Biochemical and Biophysical Research Communications. 644, p. 25-33 9 p.

    Research output: Contribution to journalArticlepeer-review

    3 Scopus citations
  • Genome-wide contribution of common short-tandem repeats to Parkinson’s disease genetic risk

    International Parkinson's Disease Genomics Consortium (IPDGC), Jan 1 2023, In: Brain. 146, 1, p. 65-74 10 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    11 Scopus citations
  • Investigation of Shared Genetic Risk Factors Between Parkinson's Disease and Cancers

    the Comprehensive Unbiased Risk Factor Assessment for Genetics and Environment in Parkinson's Disease (Courage-PD) consortium & the EPITHYR consortium, Apr 2023, In: Movement Disorders. 38, 4, p. 604-615 12 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    5 Scopus citations
  • Mechanisms of Glucocerebrosidase Dysfunction in Parkinson's Disease: Mechanisms of GBA1-PD

    Chatterjee, D. & Krainc, D., Jun 15 2023, In: Journal of Molecular Biology. 435, 12, 168023.

    Research output: Contribution to journalReview articlepeer-review

    Open Access
    5 Scopus citations
  • Misregulation of mitochondria lysosome contact dynamics in Charcot Marie Tooth Type 2B disease Rab7 mutant sensory peripheral neurons

    Wong, Y. C., Jayaraj, N. D., Belton, T. B., Shum, G. C., Ball, H. E., Ren, D., Tadenev, A. L. D., Krainc, D., Burgess, R. W. & Menichella, D. M., 2023, In: Proceedings of the National Academy of Sciences of the United States of America. 120, 44, e2313010120.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    2 Scopus citations
  • Octopamine metabolically reprograms astrocytes to confer neuroprotection against α-synuclein

    Shum, A., Zaichick, S., McElroy, G. S., Alessandro, K. D., Alasady, M. J., Novakovic, M., Peng, W., Grebenik, E. A., Chung, D., Flanagan, M. E., Smith, R., Morales, A., Stumpf, L., McGrath, K., Krainc, D., Mendillo, M. L., Prakriya, M., Chandel, N. S. & Caraveo, G., Apr 25 2023, In: Proceedings of the National Academy of Sciences of the United States of America. 120, 17, e2217396120.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    3 Scopus citations
  • Parkin regulates amino acid homeostasis at mitochondria-lysosome (M/L) contact sites in Parkinson’s disease

    Peng, W., Schröder, L. F., Song, P., Wong, Y. C. & Krainc, D., Jul 21 2023, In: Science Advances. 9, 29, eadh3347.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    11 Scopus citations
  • Parkinson's disease-linked parkin mutation disrupts recycling of synaptic vesicles in human dopaminergic neurons

    Song, P., Peng, W., Sauve, V., Fakih, R., Xie, Z., Ysselstein, D., Krainc, T., Wong, Y. C., Mencacci, N. E., Savas, J. N., Surmeier, D. J., Gehring, K. & Krainc, D., Dec 6 2023, In: Neuron. 111, 23, p. 3775-3788.e7

    Research output: Contribution to journalArticlepeer-review

    5 Scopus citations
  • Shifting the trajectory of therapeutic development for neurological and psychiatric disorders

    Krainc, D., Martin, W. J., Casey, B., Jensen, F. E., Tishkoff, S., Potter, W. Z. & Hyman, S. E., Nov 1 2023, In: Science translational medicine. 15, 720, eadg4775.

    Research output: Contribution to journalArticlepeer-review

  • Variants in ATP5F1B are associated with dominantly inherited dystonia

    Nasca, A., Mencacci, N. E., Invernizzi, F., Zech, M., Keller Sarmiento, I. J., Legati, A., Frascarelli, C., Bustos, B. I., Romito, L. M., Krainc, D., Winkelmann, J., Carecchio, M., Nardocci, N., Zorzi, G., Prokisch, H., Lubbe, S. J., Garavaglia, B. & Ghezzi, D., Jul 1 2023, In: Brain. 146, 7, p. 2730-2738 9 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    1 Scopus citations
  • 2022

    Dairy Intake and Parkinson's Disease: A Mendelian Randomization Study

    and the Comprehensive Unbiased Risk Factor Assessment for Genetics and Environment in Parkinson's Disease (Courage-PD) Consortium, Apr 2022, In: Movement Disorders. 37, 4, p. 857-864 8 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    12 Scopus citations
  • Dysregulation of organelle membrane contact sites in neurological diseases

    Kim, S., Coukos, R., Gao, F. & Krainc, D., Aug 3 2022, In: Neuron. 110, 15, p. 2386-2408 23 p.

    Research output: Contribution to journalReview articlepeer-review

    Open Access
    12 Scopus citations
  • Gene-based burden analysis of damaging private variants in PRKN, PARK7 and PINK1 in Parkinson's disease cohorts of European descent

    Hu, J., Waters, C. H., Spiegelman, D., Fon, E. A., Yu, E., Asayesh, F., Krohn, L., Saini, P., Alcalay, R. N., Hassin-Baer, S., Gan-Or, Z., Krainc, D., Zhang, B. R., Bustos, B. I. & Lubbe, S. J., Nov 2022, In: Neurobiology of Aging. 119, p. 136-138 3 p.

    Research output: Contribution to journalArticlepeer-review

  • Genome-wide Association and Meta-analysis of Age at Onset in Parkinson Disease: Evidence from the COURAGE-PD Consortium

    Grover, S., Sreelatha, A. A. K., Pihlstrom, L., Domenighetti, C., Schulte, C., Sugier, P. E., Radivojkov-Blagojevic, M., Lichtner, P., Mohamed, O., Portugal, B., Landoulsi, Z., May, P., Bobbili, D., Edsall, C., Bartusch, F., Hanussek, M., Krüger, J., Hernandez, D. G., Blauwendraat, C., Mellick, G. D., & 63 othersZimprich, A., Pirker, W., Tan, M., Rogaeva, E., Lang, A., Koks, S., Taba, P., Lesage, S., Brice, A., Corvol, J. C., Chartier-Harlin, M. C., Mutez, E., Brockmann, K., Deutschländer, A. B., Hadjigeorgiou, G. M., Dardiotis, E., Stefanis, L., Simitsi, A. M., Valente, E. M., Petrucci, S., Straniero, L., Zecchinelli, A., Pezzoli, G., Brighina, L., Ferrarese, C., Annesi, G., Quattrone, A., Gagliardi, M., Burbulla, L. F., Matsuo, H., Kawamura, Y., Hattori, N., Nishioka, K., Chung, S. J., Kim, Y. J., Pavelka, L., Van De Warrenburg, B. P. C., Bloem, B. R., Singleton, A. B., Aasly, J., Toft, M., Guedes, L. C., Ferreira, J. J., Bardien, S., Carr, J., Tolosa, E., Ezquerra, M., Pastor, P., Diez-Fairen, M., Wirdefeldt, K., Pedersen, N. L., Ran, C., Belin, A. C., Puschmann, A., Hellberg, C., Clarke, C. E., Morrison, K. E., Krainc, D., Farrer, M. J., Kruger, R., Elbaz, A., Gasser, T. & Sharma, M., Aug 16 2022, In: Neurology. 99, 7, p. E698-E710

    Research output: Contribution to journalArticlepeer-review

    Open Access
    19 Scopus citations
  • Lysosomal ceramides regulate cathepsin B-mediated processing of saposin C and glucocerebrosidase activity

    Kim, M. J., Jeong, H. & Krainc, D., Jul 15 2022, In: Human molecular genetics. 31, 14, p. 2424-2437 14 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    8 Scopus citations
  • Mendelian Randomisation Study of Smoking, Alcohol, and Coffee Drinking in Relation to Parkinson's Disease

    Domenighetti, C., Sugier, P. E., Sreelatha, A. A. K., Schulte, C., Grover, S., Mohamed, O., Portugal, B., May, P., Bobbili, D. R., Radivojkov-Blagojevic, M., Lichtner, P., Singleton, A. B., Hernandez, D. G., Edsall, C., Mellick, G. D., Zimprich, A., Pirker, W., Rogaeva, E., Lang, A. E., Koks, S., & 59 othersTaba, P., Lesage, S., Brice, A., Corvol, J. C., Chartier-Harlin, M. C., Mutez, E., Brockmann, K., Deutschländer, A. B., Hadjigeorgiou, G. M., Dardiotis, E., Stefanis, L., Simitsi, A. M., Valente, E. M., Petrucci, S., Duga, S., Straniero, L., Zecchinelli, A., Pezzoli, G., Brighina, L., Ferrarese, C., Annesi, G., Quattrone, A., Gagliardi, M., Matsuo, H., Kawamura, Y., Hattori, N., Nishioka, K., Chung, S. J., Kim, Y. J., Kolber, P., Van De Warrenburg, B. P. C., Bloem, B. R., Aasly, J., Toft, M., Pihlstrøm, L., Guedes, L. C., Ferreira, J. J., Bardien, S., Carr, J., Tolosa, E., Ezquerra, M., Pastor, P., Diez-Fairen, M., Wirdefeldt, K., Pedersen, N. L., Ran, C., Belin, A. C., Puschmann, A., Hellberg, C., Clarke, C. E., Morrison, K. E., Tan, M., Krainc, D., Burbulla, L. F., Farrer, M. J., Krüger, R., Gasser, T., Sharma, M. & Elbaz, A., 2022, In: Journal of Parkinson's disease. 12, 1, p. 267-282 16 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    17 Scopus citations
  • Mid51/Fis1 mitochondrial oligomerization complex drives lysosomal untethering and network dynamics

    Wong, Y. C., Kim, S., Cisneros, J., Molakal, C. G., Song, P., Lubbe, S. J. & Krainc, D., Oct 3 2022, In: Journal of Cell Biology. 221, 10, e202206140.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    10 Scopus citations
  • Novel bi-allelic FBXO7 variants in a family with early-onset typical Parkinson's disease

    Keller Sarmiento, I. J., Afshari, M., Kinsley, L., Silani, V., Akhtar, R. S., Simuni, T., Lubbe, S. J., Krainc, D. & Mencacci, N. E., Nov 2022, In: Parkinsonism and Related Disorders. 104, p. 88-90 3 p.

    Research output: Contribution to journalLetterpeer-review

    2 Scopus citations
  • Novel THAP1 missense variant with incomplete penetrance in a case of generalized young onset dystonia showing good response to deep brain stimulation

    Keller Sarmiento, I. J., Fraint, A., Kinsley, L., Akhtar, R. S., Silani, V., Lubbe, S. J., Krainc, D. & Mencacci, N. E., Dec 2022, In: Parkinsonism and Related Disorders. 105, p. 7-8 2 p.

    Research output: Contribution to journalLetterpeer-review

  • Polygenic Resilience Modulates the Penetrance of Parkinson Disease Genetic Risk Factors

    International Parkinson's Disease Genomics Consortium; Comprehensive Unbiased Risk Factor Assessment for Genetics and Environment in Parkinson's Disease Consortium, Aug 2022, In: Annals of neurology. 92, 2, p. 270-278 9 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    10 Scopus citations
  • The Interaction between HLA-DRB1 and Smoking in Parkinson's Disease Revisited

    Comprehensive Unbiased Risk Factor Assessment for Genetics and Environment in Parkinson's Disease (Courage-PD) Consortium, 2022, (Accepted/In press) In: Movement Disorders.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    4 Scopus citations
  • 2021

    Assessing the relationship between monoallelic PRKN mutations and Parkinson's risk

    Lubbe, S. J., Bustos, B. I., Hu, J., Krainc, D., Joseph, T., Hehir, J., Tan, M., Zhang, W., Escott-Price, V., Williams, N. M., Blauwendraat, C., Singleton, A. B. & Morris, H. R., Jan 1 2021, In: Human molecular genetics. 30, 1, p. 78-86 9 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    30 Scopus citations
  • Biallelic variants in TSPOAP1, encoding the active-zone protein RIMBP1, cause autosomal recessive dystonia

    Mencacci, N. E., Brockmann, M. M., Dai, J., Pajusalu, S., Atasu, B., Campos, J., Pino, G., Gonzalez-Latapi, P., Patzke, C., Schwake, M., Tucci, A., Pittman, A., Simon-Sanchez, J., Carvill, G. L., Balint, B., Wiethoff, S., Warner, T. T., Papandreou, A., Soo, A., Rein, R., & 15 othersKadastik-Eerme, L., Puusepp, S., Reinson, K., Tomberg, T., Hanagasi, H., Gasser, T., Bhatia, K. P., Kurian, M. A., Lohmann, E., Õunap, K., Rosenmund, C., Südhof, T. C., Wood, N. W., Krainc, D. & Acuna, C., Apr 1 2021, In: Journal of Clinical Investigation. 131, 7, e140625.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    15 Scopus citations
  • Direct targeting of wild-type glucocerebrosidase by antipsychotic quetiapine improves pathogenic phenotypes in Parkinson’s disease models

    Burbulla, L. F., Zheng, J., Song, P., Jiang, W., Johnson, M. E., Brundin, P. & Krainc, D., Oct 8 2021, In: JCI Insight. 6, 19, e148649.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    7 Scopus citations
  • Dominant mutations in MIEF1 affect mitochondrial dynamics and cause a singular late onset optic neuropathy

    Charif, M., Wong, Y. C., Kim, S., Guichet, A., Vignal, C., Zanlonghi, X., Bensaid, P., Procaccio, V., Bonneau, D., Amati-Bonneau, P., Reynier, P., Krainc, D. & Lenaers, G., Dec 2021, In: Molecular neurodegeneration. 16, 1, 12.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    14 Scopus citations
  • Dysregulation of mitochondria-lysosome contacts by GBA1 dysfunction in dopaminergic neuronal models of Parkinson’s disease

    Kim, S., Wong, Y. C., Gao, F. & Krainc, D., Dec 1 2021, In: Nature communications. 12, 1, 1807.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    97 Scopus citations
  • Evaluation of Strategies for Measuring Lysosomal Glucocerebrosidase Activity

    Ysselstein, D., Young, T. J., Nguyen, M., Padmanabhan, S., Hirst, W. D., Dzamko, N. & Krainc, D., Dec 2021, In: Movement Disorders. 36, 12, p. 2719-2730 12 p.

    Research output: Contribution to journalReview articlepeer-review

    Open Access
    21 Scopus citations
  • Glucocerebrosidase dysfunction in neurodegenerative disease

    Brooker, S. M. & Krainc, D., Dec 2021, In: Essays in Biochemistry. 65, 7, p. 873-883 11 p.

    Research output: Contribution to journalReview articlepeer-review

    4 Scopus citations
  • Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1

    Klionsky, D. J., Abdel-Aziz, A. K., Abdelfatah, S., Abdellatif, M., Abdoli, A., Abel, S., Abeliovich, H., Abildgaard, M. H., Abudu, Y. P., Acevedo-Arozena, A., Adamopoulos, I. E., Adeli, K., Adolph, T. E., Adornetto, A., Aflaki, E., Agam, G., Agarwal, A., Aggarwal, B. B., Agnello, M., Agostinis, P., & 2,909 othersAgrewala, J. N., Agrotis, A., Aguilar, P. V., Ahmad, S. T., Ahmed, Z. M., Ahumada-Castro, U., Aits, S., Aizawa, S., Akkoc, Y., Akoumianaki, T., Akpinar, H. A., Al-Abd, A. M., Al-Akra, L., Al-Gharaibeh, A., Alaoui-Jamali, M. A., Alberti, S., Alcocer-Gómez, E., Alessandri, C., Ali, M., Alim Al-Bari, M. A., Aliwaini, S., Alizadeh, J., Almacellas, E., Almasan, A., Alonso, A., Alonso, G. D., Altan-Bonnet, N., Altieri, D. C., Álvarez, É. M. C., Alves, S., Alves da Costa, C., Alzaharna, M. M., Amadio, M., Amantini, C., Amaral, C., Ambrosio, S., Amer, A. O., Ammanathan, V., An, Z., Andersen, S. U., Andrabi, S. A., Andrade-Silva, M., Andres, A. M., Angelini, S., Ann, D., Anozie, U. C., Ansari, M. Y., Antas, P., Antebi, A., Antón, Z., Anwar, T., Apetoh, L., Apostolova, N., Araki, T., Araki, Y., Arasaki, K., Araújo, W. L., Araya, J., Arden, C., Arévalo, M. A., Arguelles, S., Arias, E., Arikkath, J., Arimoto, H., Ariosa, A. R., Armstrong-James, D., Arnauné-Pelloquin, L., Aroca, A., Arroyo, D. S., Arsov, I., Artero, R., Asaro, D. M. L., Aschner, M., Ashrafizadeh, M., Ashur-Fabian, O., Atanasov, A. G., Au, A. K., Auberger, P., Auner, H. W., Aurelian, L., Autelli, R., Avagliano, L., Ávalos, Y., Aveic, S., Aveleira, C. A., Avin-Wittenberg, T., Aydin, Y., Ayton, S., Ayyadevara, S., Azzopardi, M., Baba, M., Backer, J. M., Backues, S. K., Bae, D. H., Bae, O. N., Bae, S. H., Baehrecke, E. H., Baek, A., Baek, S. H., Baek, S. H., Bagetta, G., Bagniewska-Zadworna, A., Bai, H., Bai, J., Bai, X., Bai, Y., Bairagi, N., Baksi, S., Balbi, T., Baldari, C. T., Balduini, W., Ballabio, A., Ballester, M., Balazadeh, S., Balzan, R., Bandopadhyay, R., Banerjee, S., Banerjee, S., Bánréti, Á., Bao, Y., Baptista, M. S., Baracca, A., Barbati, C., Bargiela, A., Barilà, D., Barlow, P. G., Barmada, S. J., Barreiro, E., Barreto, G. E., Bartek, J., Bartel, B., Bartolome, A., Barve, G. R., Basagoudanavar, S. H., Bassham, D. C., Bast, R. C., Basu, A., Batoko, H., Batten, I., Baulieu, E. E., Baumgarner, B. L., Bayry, J., Beale, R., Beau, I., Beaumatin, F., Bechara, L. R. G., Beck, G. R., Beers, M. F., Begun, J., Behrends, C., Behrens, G. M. N., Bei, R., Bejarano, E., Bel, S., Behl, C., Belaid, A., Belgareh-Touzé, N., Bellarosa, C., Belleudi, F., Belló Pérez, M., Bello-Morales, R., Beltran, J. S. D. O., Beltran, S., Benbrook, D. M., Bendorius, M., Benitez, B. A., Benito-Cuesta, I., Bensalem, J., Berchtold, M. W., Berezowska, S., Bergamaschi, D., Bergami, M., Bergmann, A., Berliocchi, L., Berlioz-Torrent, C., Bernard, A., Berthoux, L., Besirli, C. G., Besteiro, S., Betin, V. M., Beyaert, R., Bezbradica, J. S., Bhaskar, K., Bhatia-Kissova, I., Bhattacharya, R., Bhattacharya, S., Bhattacharyya, S., Bhuiyan, M. S., Bhutia, S. K., Bi, L., Bi, X., Biden, T. J., Bijian, K., Billes, V. A., Binart, N., Bincoletto, C., Birgisdottir, A. B., Bjorkoy, G., Blanco, G., Blas-Garcia, A., Blasiak, J., Blomgran, R., Blomgren, K., Blum, J. S., Boada-Romero, E., Boban, M., Boesze-Battaglia, K., Boeuf, P., Boland, B., Bomont, P., Bonaldo, P., Bonam, S. R., Bonfili, L., Bonifacino, J. S., Boone, B. A., Bootman, M. D., Bordi, M., Borner, C., Bornhauser, B. C., Borthakur, G., Bosch, J., Bose, S., Botana, L. M., Botas, J., Boulanger, C. M., Boulton, M. E., Bourdenx, M., Bourgeois, B., Bourke, N. M., Bousquet, G., Boya, P., Bozhkov, P. V., Bozi, L. H. M., Bozkurt, T. O., Brackney, D. E., Brandts, C. H., Braun, R. J., Braus, G. H., Bravo-Sagua, R., Bravo-San Pedro, J. M., Brest, P., Bringer, M. A., Briones-Herrera, A., Broaddus, V. C., Brodersen, P., Brodsky, J. L., Brody, S. L., Bronson, P. G., Bronstein, J. M., Brown, C. N., Brown, R. E., Brum, P. C., Brumell, J. H., Brunetti-Pierri, N., Bruno, D., Bryson-Richardson, R. J., Bucci, C., Buchrieser, C., Bueno, M., Buitrago-Molina, L. E., Buraschi, S., Buch, S., Buchan, J. R., Buckingham, E. M., Budak, H., Budini, M., Bultynck, G., Burada, F., Burgoyne, J. R., Burón, M. I., Bustos, V., Büttner, S., Butturini, E., Byrd, A., Cabas, I., Cabrera-Benitez, S., Cadwell, K., Cai, J., Cai, L., Cai, Q., Cairó, M., Calbet, J. A., Caldwell, G. A., Caldwell, K. A., Call, J. A., Calvani, R., Calvo, A. C., Calvo-Rubio Barrera, M., Camara, N. O. S., Camonis, J. H., Camougrand, N., Campanella, M., Campbell, E. M., Campbell-Valois, F. X., Campello, S., Campesi, I., Campos, J. C., Camuzard, O., Cancino, J., Candido de Almeida, D., Canesi, L., Caniggia, I., Canonico, B., Cantí, C., Cao, B., Caraglia, M., Caramés, B., Carchman, E. 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    Research output: Contribution to journalReview articlepeer-review

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    1336 Scopus citations
  • Heterozygous GBA D490V and ATP13a2 mutations do not exacerbate pathological α-synuclein spread in the prodromal preformed fibrils model in young mice

    Johnson, M. E., Bergkvist, L., Stetzik, L., Steiner, J. A., Meyerdirk, L., Schulz, E., Wolfrum, E., Luk, K. C., Wesson, D. W., Krainc, D. & Brundin, P., Nov 2021, In: Neurobiology of Disease. 159, 105513.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    11 Scopus citations
  • Identification of ASCL1 as a determinant for human iPSC-derived dopaminergic neurons

    Earley, A. M., Burbulla, L. F., Krainc, D. & Awatramani, R., Dec 2021, In: Scientific reports. 11, 1, 22257.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    4 Scopus citations
  • MED27 Variants Cause Developmental Delay, Dystonia, and Cerebellar Hypoplasia

    Meng, L., Isohanni, P., Shao, Y., Graham, B. H., Hickey, S. E., Brooks, S., Suomalainen, A., Joset, P., Steindl, K., Rauch, A., Hackenberg, A., High, F. A., Armstrong-Javors, A., Mencacci, N. E., Gonzàlez-Latapi, P., Kamel, W. A., Al-Hashel, J. Y., Bustos, B. I., Hernandez, A. V., Krainc, D., & 25 othersLubbe, S. J., Van Esch, H., De Luca, C., Ballon, K., Ravelli, C., Burglen, L., Qebibo, L., Calame, D. G., Mitani, T., Marafi, D., Pehlivan, D., Saadi, N. W., Sahin, Y., Maroofian, R., Efthymiou, S., Houlden, H., Maqbool, S., Rahman, F., Gu, S., Posey, J. E., Lupski, J. R., Hunter, J. V., Wangler, M. F., Carroll, C. J. & Yang, Y., Apr 2021, In: Annals of neurology. 89, 4, p. 828-833 6 p.

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    Open Access
    15 Scopus citations
  • Modeling Brain Pathology of Niemann-Pick Disease Type C Using Patient-Derived Neurons

    Burbulla, L. F., Mc Donald, J. M., Valdez, C., Gao, F., Bigio, E. H. & Krainc, D., Apr 2021, In: Movement Disorders. 36, 4, p. 1022-1027 6 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    3 Scopus citations
  • Replication assessment of NUS1 variants in Parkinson's disease

    International Parkinson's Disease Genomics Consortium (IPDGC), May 2021, In: Neurobiology of Aging. 101, p. 300.e1-300.e3

    Research output: Contribution to journalArticlepeer-review

    4 Scopus citations
  • 2020

    A patient-based model of RNA mis-splicing uncovers treatment targets in Parkinson's disease

    Boussaad, I., Obermaier, C. D., Hanss, Z., Bobbili, D. R., Bolognin, S., Glaab, E., Wolynska, K., Weisschuh, N., De Conti, L., May, C., Giesert, F., Grossmann, D., Lambert, A., Kirchen, S., Biryukov, M., Burbulla, L. F., Massart, F., Bohler, J., Cruciani, G., Schmid, B., & 14 othersKurz-Drexler, A., May, P., Duga, S., Klein, C., Schwamborn, J. C., Marcus, K., Woitalla, D., Weisenhorn, D. M. V., Wurst, W., Baralle, M., Krainc, D., Gasser, T., Wissinger, B. & Krüger, R., Sep 2020, In: Science translational medicine. 12, 560, eaau3960.

    Research output: Contribution to journalArticlepeer-review

    19 Scopus citations
  • Astrocytes protect human dopaminergic neurons from α-synuclein accumulation and propagation

    Tsunemi, T., Ishiguro, Y., Yoroisaka, A., Valdez, C., Miyamoto, K., Ishikawa, K., Saiki, S., Akamatsu, W., Hattori, N. & Krainc, D., Nov 4 2020, In: Journal of Neuroscience. 40, 45, p. 8618-8628 11 p.

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    54 Scopus citations
  • Author Correction: Dopamine metabolism by a monoamine oxidase mitochondrial shuttle activates the electron transport chain (Nature Neuroscience, (2020), 23, 1, (15-20), 10.1038/s41593-019-0556-3)

    Graves, S. M., Xie, Z., Stout, K. A., Zampese, E., Burbulla, L. F., Shih, J. C., Kondapalli, J., Patriarchi, T., Tian, L., Brichta, L., Greengard, P., Krainc, D., Schumacker, P. T. & Surmeier, D. J., Feb 1 2020, In: Nature neuroscience. 23, 2, p. 293 1 p.

    Research output: Contribution to journalComment/debatepeer-review

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    2 Scopus citations
  • Dopamine metabolism by a monoamine oxidase mitochondrial shuttle activates the electron transport chain

    Graves, S. M., Xie, Z., Stout, K. A., Zampese, E., Burbulla, L. F., Shih, J. C., Kondapalli, J., Patriarchi, T., Tian, L., Brichta, L., Greengard, P., Krainc, D., Schumacker, P. T. & Surmeier, D. J., Jan 1 2020, In: Nature neuroscience. 23, 1, p. 15-20 6 p.

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    89 Scopus citations
  • Gelator Length Precisely Tunes Supramolecular Hydrogel Stiffness and Neuronal Phenotype in 3D Culture

    Godbe, J. M., Freeman, R., Burbulla, L. F., Lewis, J., Krainc, D. & Stupp, S. I., Feb 10 2020, In: ACS Biomaterials Science and Engineering. 6, 2, p. 1196-1207 12 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    32 Scopus citations
  • Mitochondria-lysosome contacts regulate mitochondrial Ca2+ dynamics via lysosomal TRPML1

    Peng, W., Wong, Y. C. & Krainc, D., Aug 11 2020, In: Proceedings of the National Academy of Sciences of the United States of America. 117, 32, p. 19266-19275 10 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    155 Scopus citations