Grants per year
Personal profile
Education/Academic qualification
Cell & Molecular Biology, PhD, University of Nice, France
… → 2011
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Dive into the research topics where Dina Simkin is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
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Grants
- 5 Finished
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Investigating Divergent Disease Severity in Human Neuronal Models of KCNQ2-Related Developmental and Epilepsy Disorders
Simkin, D. (PD/PI), Simkin, D. (PD/PI), Kiskinis, E. (Co-Investigator) & Kiskinis, E. (Co-Investigator)
National Institute of Neurological Disorders and Stroke
12/1/21 → 5/31/24
Project: Research project
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Using patient specific iPSC-derived neurons to identify molecular biomarkers of drug treatment responsiveness in Dravet Syndrome
Kiskinis, E. (PD/PI) & Simkin, D. (Other)
Dravet Syndrome Foundation, Inc.
1/1/17 → 6/30/19
Project: Research project
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Synaptic substrates of age-dependent memory deficits
Disterhoft, J. F. (PD/PI), Oh, M. M. (Co-Investigator) & Simkin, D. (Other)
5/15/16 → 8/31/22
Project: Research project
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Developing Stem Cell Models to Study Dravet Syndrome
Kiskinis, E. (PD/PI) & Simkin, D. (Other)
Northwestern Memorial Hospital
1/1/16 → 12/31/16
Project: Research project
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PDR-051: Dina Simkin
Disterhoft, J. F. (Subproject PI) & Simkin, D. (Other)
Searle Funds at The Chicago Community Trust
1/1/11 → 12/31/17
Project: Research project
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Excitatory Dysfunction Drives Network and Calcium Handling Deficits in 16p11.2 Duplication Schizophrenia Induced Pluripotent Stem Cell–Derived Neurons
Parnell, E., Culotta, L., Forrest, M. P., Jalloul, H. A., Eckman, B. L., Loizzo, D. D., Horan, K. K. E., Dos Santos, M., Piguel, N. H., Tai, D. J. C., Zhang, H., Gertler, T. S., Simkin, D., Sanders, A. R., Talkowski, M. E., Gejman, P. V., Kiskinis, E., Duan, J. & Penzes, P., Jul 15 2023, In: Biological psychiatry. 94, 2, p. 153-163 11 p.Research output: Contribution to journal › Article › peer-review
Open Access10 Scopus citations -
Rescue of neuropsychiatric phenotypes in a mouse model of 16p11.2 duplication syndrome by genetic correction of an epilepsy network hub
Forrest, M. P., Dos Santos, M., Piguel, N. H., Wang, Y. Z., Hawkins, N. A., Bagchi, V. A., Dionisio, L. E., Yoon, S., Simkin, D., Martin-de-Saavedra, M. D., Gao, R., Horan, K. E., George, A. L., LeDoux, M. S., Kearney, J. A., Savas, J. N. & Penzes, P., Dec 2023, In: Nature communications. 14, 1, 825.Research output: Contribution to journal › Article › peer-review
Open Access9 Scopus citations -
Homozygous might be hemizygous: CRISPR/Cas9 editing in iPSCs results in detrimental on-target defects that escape standard quality controls
Simkin, D., Papakis, V., Bustos, B. I., Ambrosi, C. M., Ryan, S. J., Baru, V., Williams, L. A., Dempsey, G. T., McManus, O. B., Landers, J. E., Lubbe, S. J., George, A. L. & Kiskinis, E., Apr 12 2022, In: Stem cell reports. 17, 4, p. 993-1008 16 p.Research output: Contribution to journal › Article › peer-review
Open Access29 Scopus citations -
‘Channeling’ therapeutic discovery for epileptic encephalopathy through iPSC technologies
Simkin, D., Ambrosi, C., Marshall, K. A., Williams, L. A., Eisenberg, J., Gharib, M., Dempsey, G. T., George, A. L., McManus, O. B. & Kiskinis, E., May 2022, In: Trends in Pharmacological Sciences. 43, 5, p. 392-405 14 p.Research output: Contribution to journal › Review article › peer-review
Open Access10 Scopus citations -
Cognitive aging is associated with redistribution of synaptic weights in the hippocampus
Buss, E. W., Corbett, N. J., Roberts, J. G., Ybarra, N., Musial, T. F., Simkin, D., Molina-Campos, E., Oh, K. J., Nielsen, L. L., Ayala, G. D., Mullen, S. A., Farooqi, A. K., D’Souza, G. X., Hill, C. L., Bean, L. A., Rogalsky, A. E., Russo, M. L., Curlik, D. M., Antion, M. D. & Weiss, C. & 4 others, , Feb 23 2021, In: Proceedings of the National Academy of Sciences of the United States of America. 118, 8, e1921481118.Research output: Contribution to journal › Article › peer-review
Open Access27 Scopus citations