Donna G Brickner

  • 776 Citations
19972019

Research output per year

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Personal profile

Research Interests

DNA and proteins are non-randomly localized within the nucleus of the cell.  Professor Brickner's lab studies how cells control the position of genes within the nucleus, and how gene positioning affects gene expression.  When genes are activated or repressed, their position in the nucleus often changes.  The lab has identified DNA "zip codes" in the promoters of genes that control their positioning, transcription and, through an epigenetic mechanism, chromatin structure.

Education/Academic qualification

Biology/Biological Sciences, PhD, University of Michigan

… → 1999

Biology/Biological Sciences, BA, University of California, Santa Barbara

… → 1991

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Grants

Research Output

  • 776 Citations
  • 16 Article
  • 1 Chapter
  • 1 Comment/debate
  • 1 Review article

The Role of Transcription Factors and Nuclear Pore Proteins in Controlling the Spatial Organization of the Yeast Genome

Brickner, D. G., Randise-Hinchliff, C., Corbin, M. L., Liang, J. M., Kim, S., Sump, B., D'Urso, A., Kim, S. H., Satomura, A., Schmit, H., Coukos, R., Hwang, S., Watson, R. & Brickner, J. H., Jun 17 2019, In : Developmental Cell. 49, 6, p. 936-947.e4

Research output: Contribution to journalArticle

  • 5 Scopus citations

    The dynamic three-dimensional organization of the diploid yeast genome

    Kim, S., Liachko, I., Brickner, D. G., Cook, K., Noble, W. S., Brickner, J. H., Shendure, J. & Dunham, M. J., May 24 2017, In : eLife. 6, e23623.

    Research output: Contribution to journalArticle

  • 16 Scopus citations

    The dynamic three-dimensional organization of the diploid yeast genome

    Kim, S., Liachko, I., Brickner, D. G., Cook, K., Noble, W. S., Brickner, J. H., Shendure, J. & Dunham, M. J., May 24 2017, In : eLife. 6

    Research output: Contribution to journalArticle

  • 4 Scopus citations

    Strategies to regulate transcription factor-mediated gene positioning and interchromosomal clustering at the nuclear periphery

    Randise-Hinchliff, C., Coukos, R., Sood, V., Sumner, M. C., Zdraljevic, S., Sholl, L. M., Brickner, D. G., Ahmed, S., Watchmaker, L. & Brickner, J. H., Mar 16 2016, In : Journal of Cell Biology. 212, 6, p. 633-646 14 p.

    Research output: Contribution to journalArticle

  • 23 Scopus citations

    Subnuclear positioning and interchromosomal clustering of the GAL1-10 locus are controlled by separable, interdependent mechanisms

    Brickner, D. G., Sood, V., Tutucci, E., Coukos, R., Viets, K., Singer, R. H. & Brickner, J. H., Oct 1 2016, In : Molecular biology of the cell. 27, 19, p. 2980-2993 14 p.

    Research output: Contribution to journalArticle

  • 20 Scopus citations