Grants per year
Personal profile
Research Interests
Dr. Dorothy Sit is an Associate Professor at Northwestern University Feinberg School of Medicine. Dr. Sit’s main clinical research focus is on the development of treatments for women with mood disorders. Dr. Sit’s clinical work is devoted to the care of women with major mood disorders during the childbearing years including pre-conception planning, pregnancy and postpartum. With NIMH grant support, Dr. Sit recently completed a clinical trial confirming the efficacy of bright light therapy for bipolar depression and discovered that light therapy at midday versus an inactive placebo comparator induced a potent antidepressant response in depressed bipolar patients. She presented the findings at the 2016 Annual Meeting of the Society for Light Treatment and Biological Rhythms and abstracts at the American Psychiatric Association 168th Annual Meeting and the Society for Biological Psychiatry, 70th Annual Scientific Meeting. Given the robust effects, Dr. Sit is developing new research studies to investigate putative neural and visual biomarkers of response with support from NARSAD (Brain and Behavioral Research Foundation), and to explore the potential brain-related mechanisms underlying therapeutic light. As a clinician-educator, Dr. Sit serves on the women’s mental health fellowship curriculum committee and provides lectures and training for residents and fellows on the diagnosis, risks/benefit assessment and clinical management of women with depression, bipolar disorder or schizophrenia during pregnancy and postpartum. Dr. Sit serves on the Scientific Advisory Committee for the not-for-profit Center for Environmental Therapeutics and as Vice-President for the Society for Light Treatment and Biological Rhythms. She also provides peer reviews of manuscripts being considered for publication in major journals including the American Journal of Psychiatry and others.
Training Experience
1994 | Residency, University of Toronto, Canada |
2001 | Residency, University of Massachusetts Medical Center |
2002 | Fellowship, University of Massachusetts Medical Center |
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
MD, Medicine, University of Toronto
… → 1992
Research interests keywords
- Bipolar Disorder
- Depression
- Psychiatry
- Women's Health / Women's Reproductive Health
Fingerprint
- 1 Similar Profiles
Collaborations and top research areas from the last five years
Grants
- 1 Finished
-
Light Therapy for Adolescent Depression: A Scoping Review
Ballard, R., Parkhurst, J., Julian, K., Pasetes, L. N., Fawcett, A., Li, A., Goel, N. & Sit, D. K., 2023, (Accepted/In press) In: Current psychiatry reports.Research output: Contribution to journal › Review article › peer-review
-
A comparison of symptoms of bipolar and unipolar depression in postpartum women
Clark, C. T., Sit, D. K., Zumpf, K. B., Ciolino, J. D., Yang, A., Fisher, S. D. & Wisner, K. L., Apr 15 2022, In: Journal of Affective Disorders. 303, p. 82-90 9 p.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
C-Reactive protein concentrations in reproductive-aged women with major mood disorders
Torres, E., Zumpf, K. B., Ciolino, J. D., Clark, C. T., Sit, D. K., Miller, E. S. & Wisner, K. L., Jun 2022, In: Archives of Women's Mental Health. 25, 3, p. 577-584 8 p.Research output: Contribution to journal › Article › peer-review
-
Fact-checking chronotherapeutic research: Commentary on Bisdounis, et al. (2022)
Sit, D., Wu, J. C. & Gottlieb, J. F., Jun 2022, In: Neuroscience and Biobehavioral Reviews. 137, 104673.Research output: Contribution to journal › Comment/debate › peer-review
-
Trajectories of Depressive and Anxiety Symptoms Across Pregnancy and Postpartum in Selective Serotonin Reuptake Inhibitor-Treated Women
Mesches, G. A., Ciolino, J. D., Stika, C. S., Sit, D. K. Y., Zumpf, K., Fisher, S. D., Clark, C. T., George, A. L., Avram, M. J., Rasmussen-Torvik, L. J., Erickson, D. L., Caritis, S., Fischer, D., Venkataramanan, R., Costantine, M., West, H., Welch, E., Clark, S., Wisner, K. L. & Gollan, J. K., Jun 1 2022, In: Psychiatric Research and Clinical Practice. 4, 2, p. 32-41 10 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations
Datasets
-
Supplemental Material, S5 - Light Therapy for Patients With Bipolar Depression: Systematic Review and Meta-Analysis of Randomized Controlled Trials
Lam, R. W. (Creator), Teng, M. Y. (Creator), Jung, Y. (Creator), Evans, V. C. (Creator), Gottlieb, J. F. (Creator), Chakrabarty, T. (Creator), Michalak, E. E. (Creator), Murphy, J. K. (Creator), Yatham, L. N. (Creator) & Sit, D. (Creator), SAGE Journals, 2019
DOI: 10.25384/sage.11365547, https://sage.figshare.com/articles/Supplemental_Material_S5_-_Light_Therapy_for_Patients_With_Bipolar_Depression_Systematic_Review_and_Meta-Analysis_of_Randomized_Controlled_Trials/11365547
Dataset
-
Supplemental Material, S4 - Light Therapy for Patients With Bipolar Depression: Systematic Review and Meta-Analysis of Randomized Controlled Trials
Lam, R. W. (Creator), Teng, M. Y. (Creator), Jung, Y. (Creator), Evans, V. C. (Creator), Gottlieb, J. F. (Creator), Chakrabarty, T. (Creator), Michalak, E. E. (Creator), Murphy, J. K. (Creator), Yatham, L. N. (Creator) & Sit, D. (Creator), SAGE Journals, 2019
DOI: 10.25384/sage.11365541, https://sage.figshare.com/articles/Supplemental_Material_S4_-_Light_Therapy_for_Patients_With_Bipolar_Depression_Systematic_Review_and_Meta-Analysis_of_Randomized_Controlled_Trials/11365541
Dataset
-
Supplemental Material, S1 - Light Therapy for Patients With Bipolar Depression: Systematic Review and Meta-Analysis of Randomized Controlled Trials
Lam, R. W. (Creator), Teng, M. Y. (Creator), Jung, Y. (Creator), Evans, V. C. (Creator), Gottlieb, J. F. (Creator), Chakrabarty, T. (Creator), Michalak, E. E. (Creator), Murphy, J. K. (Creator), Yatham, L. N. (Creator) & Sit, D. (Creator), SAGE Journals, 2019
DOI: 10.25384/sage.11365517, https://sage.figshare.com/articles/Supplemental_Material_S1_-_Light_Therapy_for_Patients_With_Bipolar_Depression_Systematic_Review_and_Meta-Analysis_of_Randomized_Controlled_Trials/11365517
Dataset
-
Supplemental Material, S10 - Light Therapy for Patients With Bipolar Depression: Systematic Review and Meta-Analysis of Randomized Controlled Trials
Lam, R. W. (Creator), Teng, M. Y. (Creator), Jung, Y. (Creator), Evans, V. C. (Creator), Gottlieb, J. F. (Creator), Chakrabarty, T. (Creator), Michalak, E. E. (Creator), Murphy, J. K. (Creator), Yatham, L. N. (Creator) & Sit, D. (Creator), SAGE Journals, 2019
DOI: 10.25384/sage.11365520, https://sage.figshare.com/articles/Supplemental_Material_S10_-_Light_Therapy_for_Patients_With_Bipolar_Depression_Systematic_Review_and_Meta-Analysis_of_Randomized_Controlled_Trials/11365520
Dataset
-
Supplemental Material, S11 - Light Therapy for Patients With Bipolar Depression: Systematic Review and Meta-Analysis of Randomized Controlled Trials
Lam, R. W. (Creator), Teng, M. Y. (Creator), Jung, Y. (Creator), Evans, V. C. (Creator), Gottlieb, J. F. (Creator), Chakrabarty, T. (Creator), Michalak, E. E. (Creator), Murphy, J. K. (Creator), Yatham, L. N. (Creator) & Sit, D. (Creator), SAGE Journals, 2019
DOI: 10.25384/sage.11365523, https://sage.figshare.com/articles/Supplemental_Material_S11_-_Light_Therapy_for_Patients_With_Bipolar_Depression_Systematic_Review_and_Meta-Analysis_of_Randomized_Controlled_Trials/11365523
Dataset