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Edward Benjamin Thorp

  • 2404 Citations
20042023
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Personal profile

Research Interests

Cell and Molecular Immunology and Cardiovascular Disease.

Cardiovascular and Transplant Immunology

Translational Science

Training Experience

2008Postdoctoral Fellowship, Columbia University

Education/Academic qualification

PhD, Loyola University-Chicago

… → 2004

Research interests

  • Cardiovascular Diseases
  • Immunology

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  • 4 Similar Profiles
Macrophages Medicine & Life Sciences
Atherosclerosis Medicine & Life Sciences
Phagocytes Medicine & Life Sciences
Necrosis Medicine & Life Sciences
Myocardial Infarction Medicine & Life Sciences
Phagocytosis Medicine & Life Sciences
Apoptosis Medicine & Life Sciences
Inflammation Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Grants 2011 2023

Efferocytosis-Directed Inflammation Resolution and Repair in the Hypoxic Heart

Thorp, E. B.

National Heart, Lung, and Blood Institute

12/20/19 → 11/30/23

Project: Research project

5-laser 30-parameter FACSymphony-S6 SORP Cell Sorter from BD Biosciences

Abecassis, M. M., Bharat, A., Budinger, G. S., D'Aquila, R. T., Hope, T. J., Kato, A., Le Poole, I. C., Lesniak, M. S., Luo, X., Misharin, A., Perlman, H. R., Schleimer, R. P., Singer, B., Swaminathan, S., Sznajder, J. I., Tetreault, M., Thorp, E. B. & Wunderink, R. G.

Office of the Director, National Institutes of Health

8/8/19 → 8/7/20

Project: Research project

S 6
Lasers
Translational Medical Research
Health
Therapeutics

Elucidating the Roles of Resident Cardiac Macrophages in Post-Infarction Reperfusion Injury (Predoctoral Fellowship for Shang Yang Chen)

Thorp, E. B. & Winter, D. R.

American Heart Association

3/1/19 → 12/31/20

Project: Research project

Reperfusion Injury
Infarction
Macrophages
Myocardial Reperfusion Injury
Myocardial Infarction

Modeling concurrent cytomegalovirus infection and transplantation tolerance

Thorp, E. B.

Duke University, National Institute of Allergy and Infectious Diseases

3/1/19 → 2/29/20

Project: Research project

Myeloid HIFs in cardiac transplantation vasculopathy

Luo, X. & Thorp, E. B.

American Heart Association

7/1/18 → 6/30/21

Project: Research project

Heart Transplantation
Allografts
Immunosuppression
Immune System
Transplantation Tolerance

Research Output 2004 2019

3 Citations (Scopus)

A clinically relevant murine model unmasks a “two-hit” mechanism for reactivation and dissemination of cytomegalovirus after kidney transplant

Zhang, Z. J., Qiu, L., Yan, S., Wang, J. J., Thomas, P. M., Kandpal, M., Zhao, L., Iovane, A., Liu, X., Thorp, E. B., Chen, Q. C., Hummel, M. A., Kanwar, Y. S. & Abecassis, M. M., Jan 1 2019, In : American Journal of Transplantation. 19, 9, p. 2421-2433 13 p.

Research output: Contribution to journal › Article

Muromegalovirus
Cytomegalovirus
Immunosuppression
Transplants
Kidney
1 Citation (Scopus)

Cardio-omentopexy Reduces Cardiac Fibrosis and Heart Failure After Experimental Pressure Overload

Wang, J., Zhang, Q. J., Pirolli, T. J., Liu, Z. P., Powell, L. S., Thorp, E. B., Jessen, M. & Forbess, J. M., May 2019, In : Annals of Thoracic Surgery. 107, 5, p. 1448-1455 8 p.

Research output: Contribution to journal › Article

Left Ventricular Hypertrophy
Fibrosis
Heart Failure
Pressure
Thoracotomy

Dietary Saturated Fat Promotes Arrhythmia by Activating NOX2 (NADPH Oxidase 2)

Joseph, L. C., Avula, U. M. R., Wan, E. Y., Reyes, M. V., Lakkadi, K. R., Subramanyam, P., Nakanishi, K., Homma, S., Muchir, A., Pajvani, U. B., Thorp, E. B., Reiken, S. R., Marks, A. R., Colecraft, H. M. & Morrow, J. P., Nov 1 2019, In : Circulation. Arrhythmia and electrophysiology. 12, 11, p. e007573

Research output: Contribution to journal › Article

NADPH Oxidase
Dietary Fats
High Fat Diet
Cardiac Arrhythmias
Calcium-Calmodulin-Dependent Protein Kinases
14 Citations (Scopus)

Efferocytosis Fuels Requirements of Fatty Acid Oxidation and the Electron Transport Chain to Polarize Macrophages for Tissue Repair

Zhang, S., Weinberg, S., DeBerge, M., Gainullina, A., Schipma, M. J., Kinchen, J. M., Ben-Sahra, I., Gius, D. R., Yvan-Charvet, L., Chandel, N., Schumacker, P. T. & Thorp, E. B., Feb 5 2019, In : Cell Metabolism. 29, 2, p. 443-456.e5

Research output: Contribution to journal › Article

Electron Transport
Fatty Acids
Macrophages
Interleukin-10
NAD

Genome-wide differential expression profiling of lncRNAs and mRNAs associated with early diabetic cardiomyopathy

Pant, T., Dhanasekaran, A., Bai, X., Zhao, M., Thorp, E. B., Forbess, J. M., Bosnjak, Z. J. & Ge, Z. D., Dec 1 2019, In : Scientific reports. 9, 1, 15345.

Research output: Contribution to journal › Article

Open Access
Diabetic Cardiomyopathies
Long Noncoding RNA
Genome
Messenger RNA
Cardiomegaly