Edward Matthew Schaeffer

  • 7512 Citations
19992020

Research output per year

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Research Output

2020

A novel immunocompetent model of metastatic prostate cancer-induced bone pain

Liu, Z., Murphy, S. F., Huang, J., Zhao, L., Hall, C. C., Schaeffer, A. J., Schaeffer, E. M. & Thumbikat, P., Jul 1 2020, In : Prostate. 80, 10, p. 782-794 13 p.

Research output: Contribution to journalArticle

Association between inflammatory bowel disease and prostate cancer: A large-scale, prospective, population-based study

Meyers, T. J., Weiner, A. B., Graff, R. E., Desai, A. S., Cooley, L. F., Catalona, W. J., Hanauer, S. B., Wu, J. D., Schaeffer, E. M., Abdulkadir, S. A., Kundu, S. D. & Witte, J. S., 2020, (Accepted/In press) In : International Journal of Cancer.

Research output: Contribution to journalArticle

Association of Presalvage Radiotherapy PSA Levels after Prostatectomy with Outcomes of Long-Term Antiandrogen Therapy in Men with Prostate Cancer

Dess, R. T., Sun, Y., Jackson, W. C., Jairath, N. K., Kishan, A. U., Wallington, D. G., Mahal, B. A., Stish, B. J., Zumsteg, Z. S., Den, R. B., Hall, W. A., Gharzai, L. A., Jaworski, E. M., Reichert, Z. R., Morgan, T. M., Mehra, R., Schaeffer, E. M., Sartor, O., Nguyen, P. L., Lee, W. R. & 11 others, Rosenthal, S. A., Michalski, J. M., Schipper, M. J., Dignam, J. J., Pisansky, T. M., Zietman, A. L., Sandler, H. M., Efstathiou, J. A., Feng, F. Y., Shipley, W. U. & Spratt, D. E., May 2020, In : JAMA Oncology. 6, 5, p. 735-743 9 p.

Research output: Contribution to journalArticle

1 Scopus citations

CDKN1B Deletions are Associated with Metastasis in African American Men with Clinically Localized, Surgically Treated Prostate Cancer

Faisal, F. A., Murali, S., Kaur, H., Vidotto, T., Guedes, L. B., Salles, D. C., Kothari, V., Tosoian, J. J., Han, S., Hovelson, D. H., Hu, K., Spratt, D. E., Baras, A. S., Tomlins, S. A., Schaeffer, E. M. & Lotan, T. L., Jun 1 2020, In : Clinical Cancer Research. 26, 11, p. 2595-2602 8 p.

Research output: Contribution to journalArticle

Open Access

Changes in prostate-specific antigen at the time of prostate cancer diagnosis after Medicaid expansion in young men

Weiner, A. B., Vo, A. X., Desai, A. S., Hu, J. C., Spratt, D. E. & Schaeffer, E. M., Jul 15 2020, In : Cancer. 126, 14, p. 3229-3236 8 p.

Research output: Contribution to journalArticle

Genomic and clinical characterization of stromal infiltration markers in prostate cancer

Mahal, B. A., Alshalalfa, M., Zhao, S. G., Beltran, H., Chen, W. S., Chipidza, F., Davicioni, E., Karnes, R. J., Ku, S. Y., Lotan, T. L., Muralidhar, V., Rebbeck, T. R., Schaeffer, E. M., Spratt, D. E., Feng, F. Y. & Nguyen, P. L., Apr 1 2020, In : Cancer. 126, 7, p. 1407-1412 6 p.

Research output: Contribution to journalArticle

1 Scopus citations

Multidisciplinary total eradication therapy (TET) in men with newly diagnosed oligometastatic prostate cancer

Reyes, D. K., Rowe, S. P., Schaeffer, E. M., Allaf, M. E., Ross, A. E., Pavlovich, C. P., Deville, C., Tran, P. T. & Pienta, K. J., Jul 1 2020, In : Medical Oncology. 37, 7, 60.

Research output: Contribution to journalArticle

Open Access

Neuroendocrine differentiation in usual-type prostatic adenocarcinoma: Molecular characterization and clinical significance

Kaur, H., Samarska, I., Lu, J., Faisal, F., Maughan, B. L., Murali, S., Asrani, K., Alshalalfa, M., Antonarakis, E. S., Epstein, J. I., Joshu, C. E., Schaeffer, E. M., Mosquera, J. M. & Lotan, T. L., Sep 1 2020, In : Prostate. 80, 12, p. 1012-1023 12 p.

Research output: Contribution to journalArticle

Performance of clinicopathologic models in men with high risk localized prostate cancer: impact of a 22-gene genomic classifier

Tosoian, J. J., Birer, S. R., Jeffrey Karnes, R., Zhang, J., Davicioni, E., Klein, E. E., Freedland, S. J., Weinmann, S., Trock, B. J., Dess, R. T., Zhao, S. G., Jackson, W. C., Yamoah, K., Pra, A. D., Mahal, B. A., Morgan, T. M., Mehra, R., Kaffenberger, S., Salami, S. S., Kane, C. & 7 others, Pollack, A., Den, R. B., Berlin, A., Schaeffer, E. M., Nguyen, P. L., Feng, F. Y. & Spratt, D. E., 2020, (Accepted/In press) In : Prostate Cancer and Prostatic Diseases.

Research output: Contribution to journalArticle

Re: An Implementation Guide to Reducing Overtreatment of Asymptomatic Bacteriuria

Schaeffer, E. M., Feb 1 2020, In : The Journal of urology. 203, 2, 1 p.

Research output: Contribution to journalComment/debate

Re: Premenopausal Women with Recurrent Urinary Tract Infections Have Lower Quality of Life

Schaeffer, E. M., Jan 1 2020, In : The Journal of urology. 203, 1, p. 11-12 2 p.

Research output: Contribution to journalComment/debate

Risk Factors for Infection after Prostate Biopsy in the United States

Shoag, J. E., Gaffney, C., Pantuck, M., Sun, T., Gorin, M., Schaeffer, E., Sedrakyan, A., Vickers, A. & Hu, J., Apr 2020, In : Urology. 138, p. 113-118 6 p.

Research output: Contribution to journalArticle

1 Scopus citations

T-Cell Infiltration and Adaptive Treg Resistance in Response to Androgen Deprivation With or Without Vaccination in Localized Prostate Cancer

Obradovic, A. Z., Dallos, M. C., Zahurak, M. L., Partin, A. W., Schaeffer, E. M., Ross, A. E., Allaf, M. E., Nirschl, T. R., Liu, D., Chapman, C. G., O'Neal, T., Cao, H., Durham, J. N., Guner, G., Baena-Del Valle, J. A., Ertunc, O., De Marzo, A. M., Antonarakis, E. S. & Drake, C. G., Jul 1 2020, In : Clinical cancer research : an official journal of the American Association for Cancer Research. 26, 13, p. 3182-3192 11 p.

Research output: Contribution to journalArticle

1 Scopus citations

United States trends in active surveillance or watchful waiting across patient socioeconomic status from 2010 to 2015

Butler, S. S., Loeb, S., Cole, A. P., Zaslowe-Dude, C., Muralidhar, V., Kim, D. W., Schaeffer, E. M., Trinh, Q. D., Nguyen, P. L. & Mahal, B. A., Mar 1 2020, In : Prostate Cancer and Prostatic Diseases. 23, 1, p. 179-183 5 p.

Research output: Contribution to journalArticle

1 Scopus citations
2019

A comparative effectiveness analysis of the PBCG vs. PCPT risks calculators in a multi-ethnic cohort

Carbunaru, S., Nettey, O. S., Gogana, P., Helenowski, I. B., Jovanovic, B., Ruden, M., Hollowell, C. M. P., Sharifi, R., Kittles, R. A., Schaeffer, E., Gann, P. & Murphy, A. B., Nov 27 2019, In : BMC Urology. 19, 1, 121.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

African American Specific Gene Panel Predictive of Poor Prostate Cancer Outcome

Echevarria, M. I., Awasthi, S., Cheng, C. H., Berglund, A. E., Rounbehler, R. J., Gerke, T. A., Takhar, M., Davicioni, E., Klein, E. A., Freedland, S. J., Ross, A. E., Schaeffer, E. M., Den, R. B., Cleveland, J. L., Park, J. Y., Rayford, W. & Yamoah, K., Aug 1 2019, In : Journal of Urology. 202, 2, p. 247-255 9 p.

Research output: Contribution to journalArticle

Open Access

A mouse model of prostate cancer bone metastasis in a syngeneic immunocompetent host

Simons, B. W., Kothari, V., Benzon, B., Ghabili, K., Hughes, R., Zarif, J., Ross, A. E., Hurley, P. J. & Schaeffer, E. M., Jan 1 2019, In : Oncotarget. 10, 64, p. 6845-6854 10 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Association of Black Race with Prostate Cancer-Specific and Other-Cause Mortality

Dess, R. T., Hartman, H. E., Mahal, B. A., Soni, P. D., Jackson, W. C., Cooperberg, M. R., Amling, C. L., Aronson, W. J., Kane, C. J., Terris, M. K., Zumsteg, Z. S., Butler, S., Osborne, J. R., Morgan, T. M., Mehra, R., Salami, S. S., Kishan, A. U., Wang, C., Schaeffer, E. M., Roach, M. & 10 others, Pisansky, T. M., Shipley, W. U., Freedland, S. J., Sandler, H. M., Halabi, S., Feng, F. Y., Dignam, J. J., Nguyen, P. L., Schipper, M. J. & Spratt, D. E., Jul 2019, In : JAMA Oncology. 5, 7, p. 975-983 9 p.

Research output: Contribution to journalArticle

40 Scopus citations

Biologic significance of magnetic resonance imaging invisibility in localized prostate cancer

Salami, S. S., Kaplan, J. B., Nallandhighal, S., Takhar, M., Tosoian, J. J., Lee, M., Yoon, J., Hovelson, D. H., Plouffe, K. R., Kaffenberger, S. D., Schaeffer, E. M., Karnes, R. J., Lotan, T. L., Morgan, T. M., George, A. K., Montgomery, J. S., Davenport, M. S., You, S., Tomlins, S. A., Curci, N. E. & 4 others, Kim, H. L., Spratt, D. E., Udager, A. M. & Palapattu, G. S., Jan 1 2019, In : JCO Precision Oncology. 3

Research output: Contribution to journalArticle

Characterization of transcriptomic signature of primary prostate cancer analogous to prostatic small cell neuroendocrine carcinoma

Alshalalfa, M., Liu, Y., Wyatt, A. W., Gibb, E. A., Tsai, H. K., Erho, N., Lehrer, J., Takhar, M., Ramnarine, V. R., Collins, C. C., Den, R. B., Schaeffer, E. M., Davicioni, E., Lotan, T. L. & Bismar, T. A., Dec 15 2019, In : International Journal of Cancer. 145, 12, p. 3453-3461 9 p.

Research output: Contribution to journalArticle

Open Access
5 Scopus citations

Current recommendations for prostate cancer genetic testing: NCCN prostate guideline

Mohler, J. L., Higano, C. S., Schaeffer, E. M. & Cheng, H. H., Oct 1 2019, In : The Canadian journal of urology. 26, 5S2, p. 34-37 4 p.

Research output: Contribution to journalArticle

Definitive and sustained increase in prostate cancer metastases in the United States

Patel, N. A., Sedrakyan, A., Bianco, F., Etzioni, R., Gorin, M. A., Hsu, W. C., Mao, J., Nguyen, P. L., Schaeffer, E., Shoag, J., Vickers, A. & Hu, J. C., Dec 2019, In : Urologic Oncology: Seminars and Original Investigations. 37, 12, p. 988-990 3 p.

Research output: Contribution to journalArticle

1 Scopus citations

Distinct transcriptional repertoire of the androgen receptor in ETS fusion-negative prostate cancer

Berglund, A. E., Rounbehler, R. J., Gerke, T., Awasthi, S., Cheng, C. H., Takhar, M., Davicioni, E., Alshalalfa, M., Erho, N., Klein, E. A., Freedland, S. J., Ross, A. E., Schaeffer, E. M., Trock, B. J., Den, R. B., Cleveland, J. L., Park, J. Y., Dhillon, J. & Yamoah, K., May 1 2019, In : Prostate Cancer and Prostatic Diseases. 22, 2, p. 292-302 11 p.

Research output: Contribution to journalArticle

1 Scopus citations

DNA-dependent protein kinase drives prostate cancer progression through transcriptional regulation of the Wnt signaling pathway

Kothari, V., Goodwin, J. F., Zhao, S. G., Drake, J. M., Yin, Y., Chang, S. L., Evans, J. R., Wilder-Romans, K., Gabbara, K., Dylgjeri, E., Chou, J., Sun, G., Tomlins, S. A., Mehra, R., Hege, K., Filvaroff, E. H., Schaeffer, E. M., Karnes, R. J., Quigley, D. A., Rathkopf, D. E. & 9 others, He, H. H., Speers, C., Spratt, D. E., Gilbert, L. A., Ashworth, A., Chinnaiyan, A. M., Raj, G. V., Knudsen, K. E. & Feng, F. Y., Sep 15 2019, In : Clinical Cancer Research. 25, 18, p. 5608-5622 15 p.

Research output: Contribution to journalArticle

5 Scopus citations

Editorial comment

Schaeffer, E. M., May 1 2019, In : Journal of Urology. 201, 5, p. 839-840 2 p.

Research output: Contribution to journalComment/debate

Editorial comment

Schaeffer, E. M., Jan 1 2019, In : Journal of Urology. 201, 1, 1 p.

Research output: Contribution to journalComment/debate

Editorial comment

Schaeffer, E. M., May 1 2019, In : Journal of Urology. 201, 5, 1 p.

Research output: Contribution to journalComment/debate

Editorial comment

Schaeffer, E. M., Jan 1 2019, In : Journal of Urology. 201, 1, p. 10-11 2 p.

Research output: Contribution to journalComment/debate

Germline and somatic mutations in prostate cancer for the clinician

Cheng, H. H., Sokolova, A. O., Schaeffer, E. M., Small, E. J. & Higano, C. S., Jan 1 2019, In : JNCCN Journal of the National Comprehensive Cancer Network. 17, 5, p. 515-521 7 p.

Research output: Contribution to journalReview article

5 Scopus citations

High-fat diet fuels prostate cancer progression by rewiring the metabolome and amplifying the MYC program

Labbé, D. P., Zadra, G., Yang, M., Reyes, J. M., Lin, C. Y., Cacciatore, S., Ebot, E. M., Creech, A. L., Giunchi, F., Fiorentino, M., Elfandy, H., Syamala, S., Karoly, E. D., Alshalalfa, M., Erho, N., Ross, A., Schaeffer, E. M., Gibb, E. A., Takhar, M., Den, R. B. & 14 others, Lehrer, J., Karnes, R. J., Freedland, S. J., Davicioni, E., Spratt, D. E., Ellis, L., Jaffe, J. D., DʼAmico, A. V., Kantoff, P. W., Bradner, J. E., Mucci, L. A., Chavarro, J. E., Loda, M. & Brown, M., Dec 1 2019, In : Nature communications. 10, 1, 4358.

Research output: Contribution to journalArticle

Open Access
5 Scopus citations

Inflammatory Bowel Disease and the Risk of Prostate Cancer

Burns, J. A., Weiner, A. B., Catalona, W. J., Li, E. V., Schaeffer, E. M., Hanauer, S. B., Strong, S., Burns, J., Hussain, M. H. A. & Kundu, S. D., May 2019, In : European urology. 75, 5, p. 846-852 7 p.

Research output: Contribution to journalArticle

9 Scopus citations

MP68-10 HOXB13 EXPRESSION AND ITS ROLE IN PROSTATE CANCER PROGRESSION AND NEUROENDOCRINE DIFFERENTIATION

Faisal, F., Alshalalfa, M., Davicioni, E., Karnes, R. J., Isaacs, W., Lotan, T. & Schaeffer, E., Apr 1 2019, In : The Journal of urology. 201, p. e979

Research output: Contribution to journalArticle

Open Access

National practice patterns for lymph node irradiation in 197,000 men receiving external beam radiotherapy for localized prostate cancer

Weiner, A. B., Ko, O. S., Zhu, A., Spratt, D. E., Hu, J. C. & Schaeffer, E. M., Jun 2019, In : Urologic Oncology: Seminars and Original Investigations. 37, 6, p. 353.e1-353.e8

Research output: Contribution to journalArticle

1 Scopus citations

Outcomes of very high-risk prostate cancer after radical prostatectomy: Validation study from 3 centers

Sundi, D., Tosoian, J. J., Nyame, Y. A., Alam, R., Achim, M., Reichard, C. A., Li, J., Wilkins, L., Schwen, Z., Han, M., Davis, J. W., Klein, E. A., Schaeffer, E. M., Stephenson, A. J., Ross, A. E. & Chapin, B. F., Feb 1 2019, In : Cancer. 125, 3, p. 391-397 7 p.

Research output: Contribution to journalArticle

12 Scopus citations

Prostate cancer, version 2.2019

Mohler, J. L., Antonarakis, E. S., Armstrong, A. J., D'Amico, A. V., Davis, B. J., Dorff, T., Eastham, J. A., Enke, C. A., Farrington, T. A., Higano, C. S., Horwitz, E. M., Hurwitz, M., Ippolito, J. E., Kane, C. J., Kuettel, M. R., Lang, J. M., McKenney, J., Netto, G., Penson, D. F., Plimack, E. R. & 13 others, Pow-Sang, J. M., Pugh, T. J., Richey, S., Roach, M., Rosenfeld, S., Schaeffer, E., Shabsigh, A., Small, E. J., Spratt, D. E., Srinivas, S., Tward, J., Shead, D. A. & Freedman-Cass, D. A., Jan 1 2019, In : JNCCN Journal of the National Comprehensive Cancer Network. 17, 5, p. 479-505 27 p.

Research output: Contribution to journalArticle

Open Access
129 Scopus citations

Prostate cancer in sexual minorities and the influence of HIV status

Amarasekera, C., Wong, V., Yura, E., Manjunath, A., Schaeffer, E. & Kundu, S., Jul 1 2019, In : Nature Reviews Urology. 16, 7, p. 404-421 18 p.

Research output: Contribution to journalReview article

2 Scopus citations

Re: Does Size Matter? Measured and Modeled Effects of Suprapubic Catheter Size on Urinary Flow

Schaeffer, E. M., Feb 1 2019, In : Journal of Urology. 201, 2, 1 p.

Research output: Contribution to journalComment/debate

Re: Continuous Low-Dose Antibiotic Prophylaxis for Adults with Repeated Urinary Tract Infections (AnTIC): A Randomised, Open-Label Trial

Schaeffer, E. M., Fisher, H., Oluboyede, Y., Chadwick, T., Abdel-Fattah, M., Brennand, C., Fader, M., Harrison, S., Hilton, P., Larcombe, J., Little, P., McClurg, D., McColl, E., N'Dow, J., Ternent, L., Thiruchelvam, N., Timoney, A., Vale, L., Walton, K., Von Wilamowitz-Moellendorff, A. & 3 others, Wilkinson, J., Wood, R. & Pickard, R., Aug 1 2019, In : Journal of Urology. 202, 2, 1 p.

Research output: Contribution to journalComment/debate

Re: Once-Daily Plazomicin for Complicated Urinary Tract Infections

Schaeffer, E. M., Oct 1 2019, In : The Journal of urology. 202, 4, p. 641-642 2 p.

Research output: Contribution to journalComment/debate