Edwin Smith

  • 4531 Citations
19982021
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Personal profile

Education/Academic qualification

PhD, SUNY - Stony Brook

… → 1998

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Grants 2016 2021

Histone Code
Leukemia
Neoplasms
Genes
Positive Transcriptional Elongation Factor B

Research Output 1998 2019

  • 4531 Citations
  • 36 Article
  • 7 Review article
  • 2 Comment/debate
  • 2 Short survey

Correction to: Aberrant activation of non-coding RNA targets of transcriptional elongation complexes contributes to TDP-43 toxicity (Nature Communications, (2018), 9, 1, (4406), 10.1038/s41467-018-06543-0)

Chung, C. Y., Berson, A., Kennerdell, J. R., Sartoris, A., Unger, T., Porta, S., Kim, H. J., Smith, E., Shilatifard, A., Van Deerlin, V., Lee, V. M. Y., Chen-Plotkin, A. & Bonini, N. M., Dec 1 2019, In : Nature communications. 10, 1, 555.

Research output: Contribution to journalComment/debate

document markup languages
neurology
Untranslated RNA
HTML
Neurology
3 Citations (Scopus)

Aberrant activation of non-coding RNA targets of transcriptional elongation complexes contributes to TDP-43 toxicity

Chung, C. Y., Berson, A., Kennerdell, J. R., Sartoris, A., Unger, T., Porta, S., Kim, H. J., Smith, E., Shilatifard, A., Van Deerlin, V., Lee, V. M. Y., Chen-Plotkin, A. & Bonini, N. M., Dec 1 2018, In : Nature communications. 9, 1, 4406.

Research output: Contribution to journalArticle

Frontotemporal Dementia
Untranslated RNA
toxicity
elongation
Toxicity
3 Citations (Scopus)

An Mll4/COMPASS-Lsd1 epigenetic axis governs enhancer function and pluripotency transition in embryonic stem cells

Cao, K., Collings, C. K., Morgan, M. A., Marshall, S. A., Rendleman, E. J., Ozark, P. A., Smith, E. & Shilatifard, A., Jan 1 2018, In : Science Advances. 4, 1, eaap8747.

Research output: Contribution to journalArticle

Embryonic Stem Cells
Epigenomics
Chromatin
Developmental Genes
Co-Repressor Proteins
12 Citations (Scopus)

Born to run: Control of transcription elongation by RNA polymerase II

Chen, F. X., Smith, E. & Shilatifard, A., Jul 1 2018, In : Nature Reviews Molecular Cell Biology. 19, 7, p. 464-478 15 p.

Research output: Contribution to journalReview article

RNA Polymerase II
Peptide Elongation Factors
Poly(ADP-ribose) Polymerases
Genetic Promoter Regions
Genes
15 Citations (Scopus)

Resetting the epigenetic balance of Polycomb and COMPASS function at enhancers for cancer therapy

Wang, L., Zhao, Z., Ozark, P. A., Fantini, D., Marshall, S. A., Rendleman, E. J., Cozzolino, K. A., Louis, N., He, X., Morgan, M. A., Takahashi, Y., Collings, C. K., Smith, E., Ntziachristos, P., Savas, J. N., Zou, L., Hashizume, R., Meeks, J. J. & Shilatifard, A., Jun 1 2018, In : Nature Medicine. 24, 6, p. 758-769 12 p.

Research output: Contribution to journalArticle

Epigenomics
Tumors
Methyltransferases
Histones
Mutation