Eileen H Bigio

  • 22951 Citations
1989 …2020

Research output per year

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Research Output

Article

A152T tau allele causes neurodegeneration that can be ameliorated in a zebrafish model by autophagy induction

Lopez, A., Lee, S. E., Wojta, K., Ramos, E. M., Klein, E., Chen, J., Boxer, A. L., Gorno-Tempini, M. L., Geschwind, D. H., Schlotawa, L., Ogryzko, N. V., Bigio, E. H., Rogalski, E., Weintraub, S., Mesulam, M. M., Fleming, A., Coppola, G., Miller, B. L., Rubinsztein, D. C., Agosta, F. & 31 others, Alberici, A., Babacan-Yildiz, G., Bennett, D. A., Bilguvar, K., Borroni, B., Caglayan, A. O., Combarros, O., Comi, G., Cortés, E. P., Ferrer, I., Genç, Ş., Gunel, M., Gylys, K. H., Indakoetxea, B., Karageorgiou, C. E., Karydas, A., Kilic, U., De Munain, A. L., Magnani, G., Mahley, R. W., Boneschi, F. M., Martinez, J., Mazzeo, S., Moreno, F., Padovani, A., Papatriantafyllou, J., Rogaeva, E., Sanchez-Juan, P., Santangelo, R., Small, G. W. & Tauopathy Genetics Consortium, Apr 1 2017, In : Brain. 140, 4, p. 1128-1146 19 p.

Research output: Contribution to journalArticle

36 Scopus citations

A case of globular glial tauopathy presenting clinically as Alzheimer disease

SantaCruz, K. S., Rottunda, S. J., Meints, J. P., Bearer, E. L., Bigio, E. H. & McCarten, J. R., Mar 6 2015, In : Alzheimer Disease and Associated Disorders. 29, 1, p. 82-84 3 p.

Research output: Contribution to journalArticle

5 Scopus citations

Activated microglia in cortical white matter across cognitive aging trajectories

Gefen, T., Kim, G., Bolbolan, K., Geoly, A., Ohm, D., Oboudiyat, C., Shahidehpour, R., Rademaker, A., Weintraub, S., Bigio, E. H., Marsel Mesulam, M., Rogalski, E. & Geula, C., 2019, In : Frontiers in Aging Neuroscience. 11, MAY, 94.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Activation of HIPK2 Promotes ER Stress-Mediated Neurodegeneration in Amyotrophic Lateral Sclerosis

Lee, S., Shang, Y., Redmond, S. A., Urisman, A., Tang, A. A., Li, K. H., Burlingame, A. L., Pak, R. A., Jovičić, A., Gitler, A. D., Wang, J., Gray, N. S., Seeley, W. W., Siddique, T., Bigio, E. H., Lee, V. M. Y., Trojanowski, J. Q., Chan, J. R. & Huang, E. J., Jul 6 2016, In : Neuron. 91, 1, p. 41-55 15 p.

Research output: Contribution to journalArticle

41 Scopus citations

Adult polyglucosan body disease with GBE1 haploinsufficiency and concomitant frontotemporal lobar degeneration

Bit-Ivan, E. N., Lee, K. H., Gitelman, D., Weintraub, S., Mesulam, M., Rademakers, R., Isaacs, A. M., Hatanpaa, K. J., White, C. L., Mao, Q., Akman, O., Dimauro, S. & Bigio, E. H., Oct 1 2014, In : Neuropathology and Applied Neurobiology. 40, 6, p. 778-782 5 p.

Research output: Contribution to journalArticle

4 Scopus citations

Age at symptom onset and death and disease duration in genetic frontotemporal dementia: an international retrospective cohort study

Moore, K. M., Nicholas, J., Grossman, M., McMillan, C. T., Irwin, D. J., Massimo, L., Van Deerlin, V. M., Warren, J. D., Fox, N. C., Rossor, M. N., Mead, S., Bocchetta, M., Boeve, B. F., Knopman, D. S., Graff-Radford, N. R., Forsberg, L. K., Rademakers, R., Wszolek, Z. K., van Swieten, J. C., Jiskoot, L. C. & 151 others, Meeter, L. H., Dopper, E. GP., Papma, J. M., Snowden, J. S., Saxon, J., Jones, M., Pickering-Brown, S., Le Ber, I., Camuzat, A., Brice, A., Caroppo, P., Ghidoni, R., Pievani, M., Benussi, L., Binetti, G., Dickerson, B. C., Lucente, D., Krivensky, S., Graff, C., Öijerstedt, L., Fallström, M., Thonberg, H., Ghoshal, N., Morris, J. C., Borroni, B., Benussi, A., Padovani, A., Galimberti, D., Scarpini, E., Fumagalli, G. G., Mackenzie, I. R., Hsiung, G. Y. R., Sengdy, P., Boxer, A. L., Rosen, H., Taylor, J. B., Synofzik, M., Wilke, C., Sulzer, P., Hodges, J. R., Halliday, G., Kwok, J., Sanchez-Valle, R., Lladó, A., Borrego-Ecija, S., Santana, I., Almeida, M. R., Tábuas-Pereira, M., Moreno, F., Barandiaran, M., Indakoetxea, B., Levin, J., Danek, A., Rowe, J. B., Cope, T. E., Otto, M., Anderl-Straub, S., de Mendonça, A., Maruta, C., Masellis, M., Black, S. E., Couratier, P., Lautrette, G., Huey, E. D., Sorbi, S., Nacmias, B., Laforce, R., Tremblay, M. P. L., Vandenberghe, R., Damme, P. V., Rogalski, E. J., Weintraub, S., Gerhard, A., Onyike, C. U., Ducharme, S., Papageorgiou, S. G., Ng, A. S. L., Brodtmann, A., Finger, E., Guerreiro, R., Bras, J., Rohrer, J. D., Heller, C., Convery, R. S., Woollacott, I. OC., Shafei, R. M., Graff-Radford, J., Jones, D. T., Dheel, C. M., Savica, R., Lapid, M. I., Baker, M., Fields, J. A., Gavrilova, R., Domoto-Reilly, K., Poos, J. M., Van der Ende, E. L., Panman, J. L., Donker Kaat, L., Seelaar, H., Richardson, A., Frisoni, G., Mega, A., Fostinelli, S., Chiang, H. H., Alberici, A., Arighi, A., Fenoglio, C., Heuer, H., Miller, B., Karydas, A., Fong, J., João Leitão, M., Santiago, B., Duro, D., Ferreira, C., Gabilondo, A., De Arriba, M., Tainta, M., Zulaica, M., Ferreira, C., Semler, E., Ludolph, A., Landwehrmeyer, B., Volk, A. E., Miltenberger, G., Verdelho, A., Afonso, S., Tartaglia, M. C., Freedman, M., Rogaeva, E., Ferrari, C., Piaceri, I., Bessi, V., Lombardi, G., St-Onge, F., Doré, M. C., Bruffaerts, R., Vandenbulcke, M., Van den Stock, J., Mesulam, M. M., Bigio, E., Koros, C., Papatriantafyllou, J., Kroupis, C., Stefanis, L., Shoesmith, C., Robertson, E., Coppola, G., Da Silva Ramos, E. M. & Geschwind, D., Feb 2020, In : The Lancet Neurology. 19, 2, p. 145-156 12 p.

Research output: Contribution to journalArticle

Open Access
12 Scopus citations

Aging-related tau astrogliopathy (ARTAG): harmonized evaluation strategy

Kovacs, G. G., Ferrer, I., Grinberg, L. T., Alafuzoff, I., Attems, J., Budka, H., Cairns, N. J., Crary, J. F., Duyckaerts, C., Ghetti, B., Halliday, G. M., Ironside, J. W., Love, S., Mackenzie, I. R., Munoz, D. G., Murray, M. E., Nelson, P. T., Takahashi, H., Trojanowski, J. Q., Ansorge, O. & 52 others, Arzberger, T., Baborie, A., Beach, T. G., Bieniek, K. F., Bigio, E. H., Bodi, I., Dugger, B. N., Feany, M., Gelpi, E., Gentleman, S. M., Giaccone, G., Hatanpaa, K. J., Heale, R., Hof, P. R., Hofer, M., Hortobágyi, T., Jellinger, K., Jicha, G. A., Ince, P., Kofler, J., Kövari, E., Kril, J. J., Mann, D. M., Matej, R., McKee, A. C., McLean, C., Milenkovic, I., Montine, T. J., Murayama, S., Lee, E. B., Rahimi, J., Rodriguez, R. D., Rozemüller, A., Schneider, J. A., Schultz, C., Seeley, W., Seilhean, D., Smith, C., Tagliavini, F., Takao, M., Thal, D. R., Toledo, J. B., Tolnay, M., Troncoso, J. C., Vinters, H. V., Weis, S., Wharton, S. B., White, C. L., Wisniewski, T., Woulfe, J. M., Yamada, M. & Dickson, D. W., Jan 1 2016, In : Acta Neuropathologica. 131, 1, p. 87-102 16 p.

Research output: Contribution to journalArticle

180 Scopus citations

A highly sensitive sandwich ELISA to detect CSF progranulin: A potential biomarker for CNS disorders

Li, Y., Wang, D., Li, Y., Zhu, J., Zhao, J., Deng, Y., Rogalski, E. J., Bigio, E. H., Rademaker, A. W., Xia, H. & Mao, Q., Jan 1 2019, In : Journal of neuropathology and experimental neurology. 78, 5, p. 406-415 10 p.

Research output: Contribution to journalArticle

1 Scopus citations

Alterations of Ca 2+ -responsive proteins within cholinergic neurons in aging and Alzheimer's disease

Riascos, D., Nicholas, A., Samaeekia, R., Yukhananov, R., Mesulam, M-M., Bigio, E. H., Weintraub, S., Guo, L. & Geula, C., Jun 1 2014, In : Neurobiology of Aging. 35, 6, p. 1325-1333 9 p.

Research output: Contribution to journalArticle

18 Scopus citations

Alzheimer and frontotemporal pathology in subsets of primary progressive aphasia

Mesulam, M., Wicklund, A., Johnson, N., Rogalski, E., Léger, G. C., Rademaker, A., Weintraub, S. & Bigio, E. H., Jun 2008, In : Annals of neurology. 63, 6, p. 709-719 11 p.

Research output: Contribution to journalArticle

350 Scopus citations

Alzheimer's disease risk polymorphisms regulate gene expression in the ZCWPW1 and the CELF1 loci

Alzheimer's Disease Genetics Consortium (ADGC), Feb 2016, In : PloS one. 11, 2, e0148717.

Research output: Contribution to journalArticle

37 Scopus citations

Alzheimer's disease-type neuronal tau hyperphosphorylation induced by Aβ oligomers

De Felice, F. G., Wu, D., Lambert, M. P., Fernandez, S. J., Velasco, P. T., Lacor, P. N., Bigio, E. H., Jerecic, J., Acton, P. J., Shughrue, P. J., Chen-Dodson, E., Kinney, G. G. & Klein, W. L., Sep 1 2008, In : Neurobiology of Aging. 29, 9, p. 1334-1347 14 p.

Research output: Contribution to journalArticle

294 Scopus citations

An ALS-associated mutation affecting TDP-43 enhances protein aggregation, fibril formation and neurotoxicity

Guo, W., Chen, Y., Zhou, X., Kar, A., Ray, P., Chen, X., Rao, E. J., Yang, M., Ye, H., Zhu, L., Liu, J., Xu, M., Yang, Y., Wang, C., Zhang, D., Bigio, E. H., Mesulam, M., Shen, Y., Xu, Q., Fushimi, K. & 1 others, Wu, J. Y., Jul 1 2011, In : Nature Structural and Molecular Biology. 18, 7, p. 822-831 10 p.

Research output: Contribution to journalArticle

179 Scopus citations

An ALS-mutant TDP-43 neurotoxic peptide adopts an anti-parallel β-structure and induces TDP-43 redistribution

Zhu, L., Xu, M., Yang, M., Yang, Y., Li, Y., Deng, J., Ruan, L., Liu, J., Du, S., Liu, X., Feng, W., Fushimi, K., Bigio, E. H., Mesulam, M-M., Wang, C. & Wu, J., Dec 20 2014, In : Human molecular genetics. 23, 25, p. 6863-6877 15 p.

Research output: Contribution to journalArticle

29 Scopus citations

Analysis of tau haplotypes in Pick's disease

Morris, H. R., Baker, M., Yasojima, K., Houlden, H., Khan, M. N., Wood, N. W., Hardy, J., Grossman, M., Trojanowski, J., Revesz, T., Bigio, E. H., Bergeron, C., Janssen, J. C., McGeer, P. L., Rossor, M. N., Lees, A. J., Lantos, P. L. & Hutton, M., Aug 13 2002, In : Neurology. 59, 3, p. 443-445 3 p.

Research output: Contribution to journalArticle

37 Scopus citations

An immunohistochemical study of cases of sporadic and inherited frontotemporal lobar degeneration using 3R- and 4R-specific tau monoclonal antibodies

de Silva, R., Lashley, T., Strand, C., Shiarli, A. M., Shi, J., Tian, J., Bailey, K. L., Davies, P., Bigio, E. H., Arima, K., Iseki, E., Murayama, S., Kretzschmar, H., Neumann, M., Lippa, C., Halliday, G., MacKenzie, J., Ravid, R., Dickson, D., Wszolek, Z. & 6 others, Iwatsubo, T., Pickering-Brown, S. M., Holton, J., Lees, A., Revesz, T. & Mann, D. M. A., Apr 2006, In : Acta Neuropathologica. 111, 4, p. 329-340 12 p.

Research output: Contribution to journalArticle

73 Scopus citations

Anomalous binding of radiolabeled oligonucleotide probes to plaques and tangles in Alzheimer disease hippocampus

Pardue, S., White, C. L., Bigio, E. H. & Morrison-Bogorad, M., May 1994, In : Molecular and Chemical Neuropathology. 22, 1, p. 1-24 24 p.

Research output: Contribution to journalArticle

6 Scopus citations

A novel Alzheimer disease locus located near the gene encoding tau protein

Jun, G., Ibrahim-Verbaas, C. A., Vronskaya, M., Lambert, J. C., Chung, J., Naj, A. C., Kunkle, B. W., Wang, L. S., Bis, J. C., Bellenguez, C., Harold, D., Lunetta, K. L., Destefano, A. L., Grenier-Boley, B., Sims, R., Beecham, G. W., Smith, A. V., Chouraki, V., Hamilton-Nelson, K. L., Ikram, M. A. & 30 others, Fievet, N., Denning, N., Martin, E. R., Schmidt, H., Kamatani, Y., Dunstan, M. L., Valladares, O., Laza, A. R., Zelenika, D., Ramirez, A., Foroud, T. M., Choi, S. H., Boland, A., Becker, T., Kukull, W. A., Van Der Lee, S. J., Pasquier, F., Cruchaga, C., Beekly, D., Fitzpatrick, A. L., Hanon, O., Gill, M., Barber, R., Gudnason, V., Campion, D., Love, S., Bennett, D. A., Amin, N., Berr, C. & Tsolaki, M., Jan 1 2016, In : Molecular Psychiatry. 21, 1, p. 108-117 10 p.

Research output: Contribution to journalArticle

95 Scopus citations

A novel GRN mutation (GRN c.708+6-+9delTGAG) in frontotemporal lobar degeneration with TDP-43-positive inclusions: Clinicopathologic report of 6 cases

Bit-Ivan, E. N., Suh, E., Shim, H. S., Weintraub, S., Hyman, B. T., Arnold, S. E., McCarty-Wood, E., Van Deerlin, V. M., Schneider, J. A., Trojanowski, J. Q., Frosch, M. P., Baker, M. C., Rademakers, R., Mesulam, M. & Bigio, E. H., May 2014, In : Journal of neuropathology and experimental neurology. 73, 5, p. 467-473 7 p.

Research output: Contribution to journalArticle

6 Scopus citations
1 Scopus citations

Aphasic variant of Alzheimer disease

Rogalski, E., Sridhar, J., Rader, B., Martersteck, A., Chen, K., Cobia, D., Thompson, C. K., Weintraub, S., Bigio, E. H. & Mesulam, M. M., Sep 27 2016, In : Neurology. 87, 13, p. 1337-1343 7 p.

Research output: Contribution to journalArticle

24 Scopus citations

Apical dendrite degeneration, a novel cellular pathology for Betz cells in ALS

Genç, B., Jara, J. H., Lagrimas, A. K. B., Pytel, P., Roos, R. P., Mesulam, M-M., Geula, C., Bigio, E. H. & Ozdinler, P. H., Feb 6 2017, In : Scientific reports. 7, 41765.

Research output: Contribution to journalArticle

25 Scopus citations

ApoE E4 is a Susceptibility Factor in Amnestic but Not Aphasic Dementias

Rogalski, E. J., Rademaker, A., Harrison, T. M., Helenowski, I., Johnson, N., Bigio, E., Mishra, M., Weintraub, S. & Mesulam, M. M., Apr 2011, In : Alzheimer Disease and Associated Disorders. 25, 2, p. 159-163 5 p.

Research output: Contribution to journalArticle

29 Scopus citations

APOE is a correlate of phenotypic heterogeneity in Alzheimer disease in a national cohort

Weintraub, S., Teylan, M., Rader, B., Chan, K. C. G., Bollenbeck, M., Kukull, W. A., Coventry, C., Rogalski, E., Bigio, E. & Mesulam, M. M., Feb 11 2020, In : Neurology. 94, 6, p. e607-e612

Research output: Contribution to journalArticle

4 Scopus citations

Assessment of the genetic variance of late-onset Alzheimer's disease

Alzheimer's Disease Genetics Consortium (ADGC), May 1 2016, In : Neurobiology of Aging. 41, p. 200.e13-200.e20

Research output: Contribution to journalArticle

Open Access
27 Scopus citations

Association between the prevalence of learning disabilities and primary progressive aphasia

Rogalski, E. J., Rademaker, A., Wieneke, C., Bigio, E. H., Weintraub, S. & Mesulam, M. M., Dec 1 2014, In : JAMA Neurology. 71, 12, p. 1576-1577 2 p.

Research output: Contribution to journalArticle

10 Scopus citations

Association of an extended haplotype in the tau gene with progressive supranuclear palsy

Baker, M., Litvan, I., Houlden, H., Adamson, J., Dickson, D., Perez-Tur, J., Hardy, J., Lynch, T., Bigio, E. & Hutton, M., 1999, In : Human molecular genetics. 8, 4, p. 711-715 5 p.

Research output: Contribution to journalArticle

622 Scopus citations

Association of GSK3B with Alzheimer disease and frontotemporal dementia

Schaffer, B. A. J., Bertram, L., Miller, B. L., Mullin, K., Weintraub, S., Johnson, N., Bigio, E. H., Mesulam, M., Wiedau-Pazos, M., Jackson, G. R., Cummings, J. L., Cantor, R. M., Levey, A. I., Tanzi, R. E. & Geschwind, D. H., Oct 2008, In : Archives of Neurology. 65, 10, p. 1368-1374 7 p.

Research output: Contribution to journalArticle

71 Scopus citations

Association of long runs of homozygosity with Alzheimer disease among African American individuals

Ghani, M., Reitz, C., Cheng, R., Vardarajan, B. N., Jun, G., Sato, C., Naj, A., Rajbhandary, R., Wang, L. S., Valladares, O., Lin, C. F., Larson, E. B., Graff-Radford, N. R., Evans, D., De Jager, P. L., Crane, P. K., Buxbaum, J. D., Murrell, J. R., Raj, T., Ertekin-Taner, N. & 153 others, Logue, M., Baldwin, C. T., Green, R. C., Barnes, L. L., Cantwell, L. B., Fallin, M. D., Go, R. C. P., Griffith, P. A., Obisesan, T. O., Manly, J. J., Lunetta, K. L., Kamboh, M. I., Lopez, O. L., Bennett, D. A., Hendrie, H., Hall, K. S., Goate, A. M., Byrd, G. S., Kukull, W. A., Foroud, T. M., Haines, J. L., Farrer, L. A., Pericak-Vance, M. A., Lee, J. H., Schellenberg, G. D., St. George-Hyslop, P., Mayeux, R., Rogaeva, E., Albert, M. S., Albin, R. L., Apostolova, L. G., Arnold, S. E., Barber, R., Barmada, M. M., Beach, T. G., Beecham, G. W., Beekly, D., Bigio, E. H., Bird, T. D., Blacker, D., Boeve, B. F., Bowen, J. D., Boxer, A., Burke, J. R., Cai, G., Cairns, N. J., Cao, C., Carlson, C. S., Carney, R. M., Carroll, S. L., Chui, H. C., Clark, D. G., Cribbs, D. H., Crocco, E. A., Cruchaga, C., DeCarli, C., DeKosky, S. T., Demirci, F. Y., Dick, M., Faber, K. M., Fallon, K. B., Ferris, S., Frosch, M. P., Galasko, D. R., Ganguli, M., Gearing, M., Geschwind, D. H., Ghetti, B., Gilbert, J. R., Gilman, S., Glass, J. D., Growdon, J. H., Hakonarson, H., Hamilton, R. L., Hamilton-Nelson, K. L., Haroutunian, V., Harrell, L. E., Honig, L. S., Hulette, C. M., Hyman, B. T., Jarvik, G. P., Jicha, G. A., Jin, L. W., Karydas, A., Kauwe, J. S. K., Kaye, J. A., Kim, R., Koo, E. H., Kowall, N. W., Kramer, J. H., Kramer, P., LaFerla, F. M., Lah, J. J., Lang-Walker, R., Leverenz, J. B., Levey, A. I., Li, G., Lieberman, A. P., Lyketsos, C. G., Mack, W. J., Marson, D. C., Martiniuk, F., Mash, D. C., Masliah, E., McCormick, W. C., McCurry, S. M., McDavid, A. N., McKee, A. C., Mesulam, M., Miller, B. L., Miller, C. A., Miller, J. W., Montine, T. J., Morris, J. C., Olichney, J. M., Parisi, J. E., Peskind, E., Petersen, R. C., Pierce, A., Poon, W. W., Potter, H., Quinn, J. F., Raj, A., Raskind, M., Reiman, E. M., Reisberg, B., Ringman, J. M., Roberson, E. D., Sano, M., Saykin, A. J., Schneider, J. A., Schneider, L. S., Seeley, W. W., Smith, A. G., Sonnen, J. A., Spina, S., Stern, R. A., Tanzi, R. E., Trojanowski, J. Q., Troncoso, J. C., Tsuang, D. W., Van Deerlin, V. M., Van Eldik, L. J., Vinters, H. V., Vonsattel, J. P., Weintraub, S., Welsh-Bohmer, K. A., Williamson, J., Woltjer, R. L., Wright, C. B., Younkin, S. G., Yu, C. E. & Yu, L., Nov 2015, In : JAMA Neurology. 72, 11, p. 1313-1323 11 p.

Research output: Contribution to journalArticle

18 Scopus citations

Associations between Potentially Modifiable Risk Factors and Alzheimer Disease: A Mendelian Randomization Study

Alzheimer’s Disease Genetics Consortium, The GERAD1 Consortium & EPIC-InterAct Consortium, Jun 1 2015, In : PLoS medicine. 12, 6, e1001841.

Research output: Contribution to journalArticle

74 Scopus citations

Associations of MAP2K3 gene variants with superior memory in SuperAgers

for the Alzheimer's Disease Neuroimaging Initiative, May 29 2018, In : Frontiers in Aging Neuroscience. 10, MAY, 155.

Research output: Contribution to journalArticle

6 Scopus citations

Asymmetric pathology in primary progressive aphasia with progranulin mutations and TDP inclusions

Kim, G., Ahmadian, S. S., Peterson, M., Parton, Z., Memon, R., Weintraub, S., Rademaker, A., Bigio, E., Mesulam, M. M. & Geula, C., Feb 16 2016, In : Neurology. 86, 7, p. 627-636 10 p.

Research output: Contribution to journalArticle

17 Scopus citations

Asymmetric TDP-43 distribution in primary progressive aphasia with progranulin mutation

Gliebus, G., Bigio, E. H., Gasho, K., Mishra, M., Caplan, D., Mesulam, M. M. & Geula, C., May 18 2010, In : Neurology. 74, 20, p. 1607-1610 4 p.

Research output: Contribution to journalArticle

20 Scopus citations

Asymmetric TDP pathology in primary progressive aphasia with right hemisphere language dominance

Kim, G., Vahedi, S., Gefen, T., Weintraub, S., Bigio, E. H., Mesulam, M. M. & Geula, C., Jan 30 2018, In : Neurology. 90, 5, p. e396-e403

Research output: Contribution to journalArticle

5 Scopus citations

Asymmetry and heterogeneity of Alzheimer's and frontotemporal pathology in primary progressive aphasia

Mesulam, M. M., Weintraub, S., Rogalski, E. J., Wieneke, C., Geula, C. & Bigio, E. H., Apr 2014, In : Brain. 137, 4, p. 1176-1192 17 p.

Research output: Contribution to journalArticle

161 Scopus citations

Ataxin-2 as potential disease modifier in C9ORF72 expansion carriers

van Blitterswijk, M., Mullen, B., Heckman, M. G., Baker, M. C., DeJesus-Hernandez, M., Brown, P. H., Murray, M. E., Hsiung, G. Y. R., Stewart, H., Karydas, A. M., Finger, E., Kertesz, A., Bigio, E. H., Weintraub, S., Mesulam, M., Hatanpaa, K. J., White, C. L., Neumann, M., Strong, M. J., Beach, T. G. & 17 others, Wszolek, Z. K., Lippa, C., Caselli, R., Petrucelli, L., Josephs, K. A., Parisi, J. E., Knopman, D. S., Petersen, R. C., Mackenzie, I. R., Seeley, W. W., Grinberg, L. T., Miller, B. L., Boylan, K. B., Graff-Radford, N. R., Boeve, B. F., Dickson, D. W. & Rademakers, R., Oct 2014, In : Neurobiology of Aging. 35, 10, p. 2421.e13-2421.e17

Research output: Contribution to journalArticle

61 Scopus citations

Ataxin-2 repeat-length variation and neurodegeneration

Ross, O. A., Rutherford, N. J., Baker, M., Soto-Ortolaza, A. I., Carrasquillo, M. M., DeJesus-Hernandez, M., Adamson, J., Li, M., Volkening, K., Finger, E., Seeley, W. W., Hatanpaa, K. J., Lomen-Hoerth, C., Kertesz, A., Bigio, E. H., Lippa, C., Woodruff, B. K., Knopman, D. S., White, C. L., Van Gerpen, J. A. & 13 others, Meschia, J. F., Mackenzie, I. R., Boylan, K., Boeve, B. F., Miller, B. L., Strong, M. J., Uitti, R. J., Younkin, S. G., Graff-Radford, N. R., Petersen, R. C., Wszolek, Z. K., Dickson, D. W. & Rademakers, R., Aug 2011, In : Human molecular genetics. 20, 16, p. 3207-3212 6 p.

Research output: Contribution to journalArticle

116 Scopus citations
4 Scopus citations

Brain blood flow in the dementias: SPECT with histopathologic correlation

Bonte, F. J., Tintner, R., Weiner, M. F., Bigio, E. H. & White, C. L., Feb 1993, In : Radiology. 186, 2, p. 361-365 5 p.

Research output: Contribution to journalArticle

54 Scopus citations

Brain blood flow in the dementias: SPECT with histopathologic correlation in 54 patients

Bonte, F. J., Weiner, M. F., Bigio, E. H. & White, C. L., Jan 1 1997, In : Radiology. 202, 3, p. 793-797 5 p.

Research output: Contribution to journalArticle

83 Scopus citations

C9ORF72 repeat expansions in cases with previously identified pathogenic mutations

Van Blitterswijk, M., Baker, M. C., Hernandez, M., Ghidoni, R., Benussi, L., Finger, E., Hsiung, G. Y. R., Kelley, B. J., Murray, M. E., Rutherford, N. J., Brown, P. E., Ravenscroft, T., Mullen, B., Ash, P. E. A., Bieniek, K. F., Hatanpaa, K. J., Karydas, A., Wood, E. M. C., Coppola, G., Bigio, E. H. & 22 others, Lippa, C., Strong, M. J., Beach, T. G., Knopman, D. S., Huey, E. D., Mesulam, M., Bird, T., White, C. L., Kertesz, A., Geschwind, D. H., Van Deerlin, V. M., Petersen, R. C., Binetti, G., Miller, B. L., Petrucelli, L., Wszolek, Z. K., Boylan, K. B., Graff-Radford, N. R., MacKenzie, I. R., Boeve, B. F., Dickson, D. W. & Rademakers, R., Oct 8 2013, In : Neurology. 81, 15, p. 1332-1341 10 p.

Research output: Contribution to journalArticle

66 Scopus citations

Calbindin-D28K, parvalbumin, and calretinin in young and aged human locus coeruleus

Lamerand, S., Shahidehpour, R., Ayala, I., Gefen, T., Mesulam, M. M., Bigio, E. & Geula, C., Oct 2020, In : Neurobiology of Aging. 94, p. 243-249 7 p.

Research output: Contribution to journalArticle

Calpain-mediated tau cleavage: A mechanism leading to neurodegeneration shared by multiple tauopathies

Ferreira, A. & Bigio, E. H., Jul 2011, In : Molecular Medicine. 17, 7-8, p. 676-685 10 p.

Research output: Contribution to journalArticle

62 Scopus citations

Can Alzheimer's Disease and Dementias with Lewy Bodies Be Distinguished Clinically?

Weiner, M. F., Hynan, L. S., Parikh, B., Zaki, N., White, C. L., Bigio, E. H., Lipton, A. M., Martin-Cook, K., Svetlik, D. A., Cullum, C. M., Vobach, S. & Rosenberg, R. N., Dec 1 2003, In : Journal of Geriatric Psychiatry and Neurology. 16, 4, p. 245-250 6 p.

Research output: Contribution to journalArticle

37 Scopus citations

Cerebrospinal fluid markers detect Alzheimer's disease in nonamnestic dementia

Oboudiyat, C., Gefen, T., Varelas, E., Weintraub, S., Rogalski, E., Bigio, E. H. & Mesulam, M. M., May 2017, In : Alzheimer's and Dementia. 13, 5, p. 598-601 4 p.

Research output: Contribution to journalArticle

4 Scopus citations

Clinical and cortical decline in the aphasic variant of Alzheimer's disease

Rogalski, E. J., Sridhar, J., Martersteck, A., Rader, B., Cobia, D. J., Arora, A. K., Fought, A. J., Bigio, E. H., Weintraub, S., Mesulam, M. M. & Rademaker, A., Apr 2019, In : Alzheimer's and Dementia. 15, 4, p. 543-552 10 p.

Research output: Contribution to journalArticle

Clinical and neuropathological features of ALS/FTD with TIA1 mutations

Hirsch-Reinshagen, V., Pottier, C., Nicholson, A. M., Baker, M., Hsiung, G. Y. R., Krieger, C., Sengdy, P., Boylan, K. B., Dickson, D. W., Mesulam, M., Weintraub, S., Bigio, E., Zinman, L., Keith, J., Rogaeva, E., Zivkovic, S. A., Lacomis, D., Taylor, J. P., Rademakers, R. & Mackenzie, I. R. A., Dec 7 2017, In : Acta Neuropathologica Communications. 5, 1, p. 96 1 p.

Research output: Contribution to journalArticle

15 Scopus citations

Clinical and neuropathologic variation in neuronal intermediate filament inclusion disease

Cairns, N. J., Grossman, M., Arnold, S. E., Burn, D. J., Jaros, E., Perry, R. H., Duyckaerts, C., Stankoff, B., Pillon, B., Skullerud, K., Cruz-Sanchez, F. F., Bigio, E. H., Mackenzie, I. R. A., Gearing, M., Juncos, J. L., Glass, J. D., Yokoo, H., Nakazato, Y., Mosaheb, S., Thorpe, J. R. & 3 others, Uryu, K., Lee, V. M. Y. & Trojanowski, J. Q., Oct 26 2004, In : Neurology. 63, 8, p. 1376-1384 9 p.

Research output: Contribution to journalArticle

137 Scopus citations

Clinically concordant variations of Alzheimer pathology in aphasic versus amnestic dementia

Gefen, T., Gasho, K., Rademaker, A., Lalehzari, M., Weintraub, S., Rogalski, E., Wieneke, C., Bigio, E., Geula, C. & Mesulam, M. M., May 2012, In : Brain. 135, 5, p. 1554-1565 12 p.

Research output: Contribution to journalArticle

81 Scopus citations

Clinicopathologic correlation in PGRN mutations

Davion, S., Johnson, N., Weintraub, S., Mesulam, M-M., Engberg, A., Mishra, M., Baker, M., Adamson, J., Hutton, M., Rademakers, R. & Bigio, E. H., Jan 1 2007, In : Neurology. 69, 11, p. 1113-1121 9 p.

Research output: Contribution to journalArticle

45 Scopus citations