Eileen H Bigio

  • 22820 Citations
1989 …2020

Research output per year

If you made any changes in Pure these will be visible here soon.

Research Output

Filter
Article
1989

Disseminated cytomegalovirus infection presenting with acalculous cholecystitis and acute pancreatitis

Bigio, E. H. & Haque, A. K., Jan 1 1989, In : Archives of Pathology and Laboratory Medicine. 113, 11, p. 1287-1289 3 p.

Research output: Contribution to journalArticle

15 Scopus citations
1990

Identification of Campylobacter pylori by endoscopic brush cytology

Schnadig, V. J., Bigio, E. H., Gourley, W. K., Stewart, G. D., Newton, G. A. & Shabot, J. M., Jan 1 1990, In : Diagnostic cytopathology. 6, 4, p. 227-234 8 p.

Research output: Contribution to journalArticle

13 Scopus citations
1993

Brain blood flow in the dementias: SPECT with histopathologic correlation

Bonte, F. J., Tintner, R., Weiner, M. F., Bigio, E. H. & White, C. L., Feb 1993, In : Radiology. 186, 2, p. 361-365 5 p.

Research output: Contribution to journalArticle

54 Scopus citations
1994

Anomalous binding of radiolabeled oligonucleotide probes to plaques and tangles in Alzheimer disease hippocampus

Pardue, S., White, C. L., Bigio, E. H. & Morrison-Bogorad, M., May 1994, In : Molecular and Chemical Neuropathology. 22, 1, p. 1-24 24 p.

Research output: Contribution to journalArticle

6 Scopus citations
1997

Brain blood flow in the dementias: SPECT with histopathologic correlation in 54 patients

Bonte, F. J., Weiner, M. F., Bigio, E. H. & White, C. L., Jan 1 1997, In : Radiology. 202, 3, p. 793-797 5 p.

Research output: Contribution to journalArticle

83 Scopus citations

Frequency of unilateral and bilateral mesial temporal sclerosis in primary and secondary epilepsy: A forensic autopsy study

Rushing, E. J., Barnard, J. J., Bigio, E. H., Eagan, K. P. & White, C. L., Dec 1 1997, In : American Journal of Forensic Medicine and Pathology. 18, 4, p. 335-341 7 p.

Research output: Contribution to journalArticle

9 Scopus citations
1998

Dementia associated with cortical dysplasia

Bigio, E. H., Fontaine, C. S., Anas Dababo, M., Prahlow, J. A., Chason, D. P., Weiner, M. F. & White, C. L., Feb 27 1998, In : Acta Neuropathologica. 95, 2, p. 193-198 6 p.

Research output: Contribution to journalArticle

3 Scopus citations

Evidence for regulated expression of neuropeptide Y gene by rat and human cultured astrocytes

Barnea, A., Aguila-Mansilla, N., Bigio, E. H., Carolyn Worby, W. & Roberts, J., Sep 25 1998, In : Regulatory Peptides. 75-76, p. 293-300 8 p.

Research output: Contribution to journalArticle

20 Scopus citations

Neocortical synapse density and braak stage in the lewy body variant of Alzheimer disease: A comparison with classic Alzheimer disease and normal aging

Brown, D. F., Risser, R. C., Bigio, E. H., Tripp, P., Stiegler, A., Welch, E., Eagan, K. P., Hladik, C. L. & White, C. L., Jan 1 1998, In : Journal of Neuropathology and Experimental Neurology. 57, 10, p. 955-960 6 p.

Research output: Contribution to journalArticle

63 Scopus citations

Neuropathologic evidence that the lewy body variant of Alzheimer disease represents coexistence of Alzheimer disease and idiopathic Parkinson disease

Brown, D. F., Dababo, M. A., Bigio, E. H., Risser, R. C., Eagan, K. P., Hladik, C. L. & White, C. L., Jan 1998, In : Journal of neuropathology and experimental neurology. 57, 1, p. 39-46 8 p.

Research output: Contribution to journalArticle

Open Access
56 Scopus citations

Primary epithelioid hemangioendothelioma of the clivus

Rushing, E. J., White, J. A., D' Alise, M. D., Chason, D. P., White, C. L. & Bigio, E. H., Mar 1 1998, In : Clinical Neuropathology. 17, 2, p. 110-114 5 p.

Research output: Contribution to journalArticle

23 Scopus citations

Response

Brown, D. F., Bigio, E. H. & White, C. L., Jan 1 1998, In : Journal of Neuropathology and Experimental Neurology. 57, 5, 1 p.

Research output: Contribution to journalArticle

The wide spectrum of myofibrillar myopathy suggests a multifactorial etiology and pathogenesis

Amato, A. A., Kagan-Hallet, K., Jackson, C. E., Lampkin, S., Wolfe, G. I., Ferrante, M., Bigio, E. H. & Barohn, R. J., Jan 1 1998, In : Neurology. 51, 6, p. 1646-1655 10 p.

Research output: Contribution to journalArticle

44 Scopus citations
1999

Association of an extended haplotype in the tau gene with progressive supranuclear palsy

Baker, M., Litvan, I., Houlden, H., Adamson, J., Dickson, D., Perez-Tur, J., Hardy, J., Lynch, T., Bigio, E. & Hutton, M., 1999, In : Human molecular genetics. 8, 4, p. 711-715 5 p.

Research output: Contribution to journalArticle

621 Scopus citations

Progressive supranuclear palsy with dementia: Cortical pathology

Bigio, E. H., Brown, D. F. & White, C. L., Apr 1999, In : Journal of neuropathology and experimental neurology. 58, 4, p. 359-364 6 p.

Research output: Contribution to journalArticle

62 Scopus citations

Radiation change versus recurrent astrocytoma: Diagnostic utility of the proliferation index?

Bigio, E. H., Colvin, S. M., Mickey, B. E., White, C. L. & Rushing, E. J., Apr 16 1999, In : Journal of Neuro-Oncology. 41, 1, p. 55-63 9 p.

Research output: Contribution to journalArticle

8 Scopus citations
2000

Glutamate transporter EAAT2 splice variants occur not only in ALS, but also in AD and controls

Honig, L. S., Chambliss, D. D., Bigio, E. H., Carroll, S. L. & Elliott, J. L., Oct 24 2000, In : Neurology. 55, 8, p. 1082-1088 7 p.

Research output: Contribution to journalArticle

85 Scopus citations

Neurophysiologic and neuroradiologic features of intractable epilepsy after traumatic brain injury in adults

Diaz-Arrastia, R., Agostini, M. A., Frol, A. B., Mickey, B., Fleckenstein, J., Bigio, E. & Van Ness, P. C., 2000, In : Archives of Neurology. 57, 11, p. 1611-1616 6 p.

Research output: Contribution to journalArticle

90 Scopus citations
2001

Contribution of asymmetric synapse loss to lateralizing clinical deficits in frontotemporal dementias

Lipton, A. M., Munro Cullum, C., Satumtira, S., Sontag, E., Hynan, L. S., White, C. L. & Bigio, E. H., 2001, In : Archives of Neurology. 58, 8, p. 1233-1239 7 p.

Research output: Contribution to journalArticle

45 Scopus citations

Cortical synapse loss in progressive supranuclear palsy

Bigio, E. H., Vono, M. B., Satumtira, S., Adamson, J., Sontag, E., Hynan, L. S., White, C. L., Baker, M. & Hutton, M., May 2001, In : Journal of neuropathology and experimental neurology. 60, 5, p. 403-410 8 p.

Research output: Contribution to journalArticle

31 Scopus citations

Corticobasal degeneration and progressive supranuclear palsy share a common tau haplotype

Houlden, H., Baker, M., Morris, H. R., MacDonald, N., Pickering-Brown, S., Adamson, J., Lees, A. J., Rossor, M. N., Quinn, N. P., Kertesz, A., Khan, M. N., Hardy, J., Lantos, P. L., St. George-Hyslop, P., Munoz, D. G., Mann, D., Lang, A. E., Bergeron, C., Bigio, E. H., Litvan, I. & 4 others, Bhatia, K. P., Dickson, D., Wood, N. W. & Hutton, M., Jun 26 2001, In : Neurology. 56, 12, p. 1702-1706 5 p.

Research output: Contribution to journalArticle

324 Scopus citations

Frontal lobe dementia with novel tauopathy: Sporadic multiple system tauopathy with dementia

Bigio, E. H., Lipton, A. M., Yen, S. H., Hutton, M. L., Baker, M., Nacharaju, P., White, C. L., Davies, P., Lin, W. & Dickson, D. W., 2001, In : Journal of neuropathology and experimental neurology. 60, 4, p. 328-341 14 p.

Research output: Contribution to journalArticle

66 Scopus citations
2002

Analysis of tau haplotypes in Pick's disease

Morris, H. R., Baker, M., Yasojima, K., Houlden, H., Khan, M. N., Wood, N. W., Hardy, J., Grossman, M., Trojanowski, J., Revesz, T., Bigio, E. H., Bergeron, C., Janssen, J. C., McGeer, P. L., Rossor, M. N., Lees, A. J., Lantos, P. L. & Hutton, M., Aug 13 2002, In : Neurology. 59, 3, p. 443-445 3 p.

Research output: Contribution to journalArticle

37 Scopus citations

Neurocysticercosis

Oeberst, J. L., Barnard, J. J., Bigio, E. H. & Prahlow, J. A., Mar 25 2002, In : American Journal of Forensic Medicine and Pathology. 23, 1, p. 31-35 5 p.

Research output: Contribution to journalArticle

7 Scopus citations

Synapse loss is greater in presenile than senile onset alzheimer disease: Implications for the cognitive reserve hypothesis

Bigio, E. H., Hynan, L. S., Sontag, E., Satumtira, S. & White, C. L., 2002, In : Neuropathology and Applied Neurobiology. 28, 3, p. 218-227 10 p.

Research output: Contribution to journalArticle

66 Scopus citations
2003

Can Alzheimer's Disease and Dementias with Lewy Bodies Be Distinguished Clinically?

Weiner, M. F., Hynan, L. S., Parikh, B., Zaki, N., White, C. L., Bigio, E. H., Lipton, A. M., Martin-Cook, K., Svetlik, D. A., Cullum, C. M., Vobach, S. & Rosenberg, R. N., Dec 1 2003, In : Journal of Geriatric Psychiatry and Neurology. 16, 4, p. 245-250 6 p.

Research output: Contribution to journalArticle

37 Scopus citations

Cognitive impairment, frontotemporal dementia, and the motor neuron diseases

Strong, M. J., Lomen-Hoerth, C., Caselli, R. J., Bigio, E. H. & Yang, W., Jul 1 2003, In : Annals of neurology. 54, SUPPL. 5, p. S20-S23

Research output: Contribution to journalArticle

96 Scopus citations

Frontotemporal and motor neurone degeneration with neurofilament inclusion bodies: Additional evidence for overlap between FTD and ALS

Bigio, E. H., Lipton, A. M., White, C. L., Dickson, D. W. & Hirano, A., Jun 2003, In : Neuropathology and Applied Neurobiology. 29, 3, p. 239-253 15 p.

Research output: Contribution to journalArticle

93 Scopus citations

Synapse loss may be a minor contributor to decreased regional cerebral blood flow in Alzheimer disease

Bigio, E. H., Reisch, J. S., White, C. L., Satumtira, S., Sontag, E. & Bonte, F. J., 2003, In : Dementia and Geriatric Cognitive Disorders. 15, 2, p. 72-78 7 p.

Research output: Contribution to journalArticle

2 Scopus citations
2004

Clinical and neuropathologic variation in neuronal intermediate filament inclusion disease

Cairns, N. J., Grossman, M., Arnold, S. E., Burn, D. J., Jaros, E., Perry, R. H., Duyckaerts, C., Stankoff, B., Pillon, B., Skullerud, K., Cruz-Sanchez, F. F., Bigio, E. H., Mackenzie, I. R. A., Gearing, M., Juncos, J. L., Glass, J. D., Yokoo, H., Nakazato, Y., Mosaheb, S., Thorpe, J. R. & 3 others, Uryu, K., Lee, V. M. Y. & Trojanowski, J. Q., Oct 26 2004, In : Neurology. 63, 8, p. 1376-1384 9 p.

Research output: Contribution to journalArticle

137 Scopus citations

Frontotemporal lobar degeneration with motor neuron disease-type inclusions predominates in 76 cases of frontotemporal degeneration

Lipton, A. M., White, C. L. & Bigio, E. H., Nov 1 2004, In : Acta Neuropathologica. 108, 5, p. 379-385 7 p.

Research output: Contribution to journalArticle

159 Scopus citations

Lateralization on neuroimaging does not differentiate frontotemporal lobar degeneration from Alzheimer's disease

Lipton, A. M., Benavides, R., Hynan, L. S., Bonte, F. J., Harris, T. S., White, C. L. & Bigio, E. H., Jun 15 2004, In : Dementia and Geriatric Cognitive Disorders. 17, 4, p. 324-327 4 p.

Research output: Contribution to journalArticle

7 Scopus citations

Most cases of dementia with hippocampal sclerosis may represent frontotemporal dementia

Hatanpaa, K. J., Blass, D. M., Pletnikova, O., Crain, B. J., Bigio, E. H., Hedreen, J. C., White, C. L. & Troncoso, J. C., Aug 10 2004, In : Neurology. 63, 3, p. 538-542 5 p.

Research output: Contribution to journalArticle

67 Scopus citations
36 Scopus citations

Synaptic targeting by Alzheimer's-related amyloid β oligomers

Lacor, P. N., Buniel, M. C., Chang, L., Fernandez, S. J., Gong, Y., Viola, K. L., Lambert, M. P., Velasco, P. T., Bigio, E. H., Finch, C. E., Krafft, G. A. & Klein, W. L., Nov 10 2004, In : Journal of Neuroscience. 24, 45, p. 10191-10200 10 p.

Research output: Contribution to journalArticle

779 Scopus citations

Tau epitope display in progressive supranuclear palsy and corticobasal degeneration

Berry, R. W., Sweet, A. P., Clark, F. A., Lagalwar, S., Lapin, B. R., Wang, T., Topgi, S., Guillozet-Bongaarts, A. L., Cochran, E. J., Bigio, E. H. & Binder, L. I., May 1 2004, In : Journal of Neurocytology. 33, 3, p. 287-295 9 p.

Research output: Contribution to journalArticle

31 Scopus citations

α-Internexin aggregates are abundant in neuronal intermediate filament inclusion disease (NIFID) but rare in other neurodegenerative diseases

Cairns, N. J., Uryu, K., Bigio, E. H., Mackenzie, I. R. A., Gearing, M., Duyckaerts, C., Yokoo, H., Nakazato, Y., Jaros, E., Perry, R. H., Arnold, S. E., Lee, V. M. Y. & Trojanowski, J. Q., Sep 1 2004, In : Acta Neuropathologica. 108, 3, p. 213-223 11 p.

Research output: Contribution to journalArticle

44 Scopus citations

α-internexin is present in the pathological inclusions of neuronal intermediate filament inclusion disease

Cairns, N. J., Zhukareva, V., Uryu, K., Zhang, B., Bigio, E., Mackenzie, I. R. A., Gearing, M., Duyckaerts, C., Yokoo, H., Nakazato, Y., Jaros, E., Perry, R. H., Lee, V. M. Y. & Trojanowski, J. Q., Jun 2004, In : American Journal of Pathology. 164, 6, p. 2153-2161 9 p.

Research output: Contribution to journalArticle

101 Scopus citations
2005

Neuronal intranuclear inclusions are ultrastructurally and immunologically distinct from cytoplasmic inclusions of neuronal intermediate filament inclusion disease

Mosaheb, S., Thorpe, J. R., Hashemzadeh-Bonehi, L., Bigio, E. H., Gearing, M. & Cairns, N. J., Oct 1 2005, In : Acta Neuropathologica. 110, 4, p. 360-368 9 p.

Research output: Contribution to journalArticle

17 Scopus citations

Tau truncation during neurofibrillary tangle evolution in Alzheimer's disease

Guillozet-Bongaarts, A. L., Garcia-Sierra, F., Reynolds, M. R., Horowitz, P. M., Fu, Y., Wang, T., Cahill, M. E., Bigio, E. H., Berry, R. W. & Binder, L. I., Jul 2005, In : Neurobiology of Aging. 26, 7, p. 1015-1022 8 p.

Research output: Contribution to journalArticle

172 Scopus citations
2006

An immunohistochemical study of cases of sporadic and inherited frontotemporal lobar degeneration using 3R- and 4R-specific tau monoclonal antibodies

de Silva, R., Lashley, T., Strand, C., Shiarli, A. M., Shi, J., Tian, J., Bailey, K. L., Davies, P., Bigio, E. H., Arima, K., Iseki, E., Murayama, S., Kretzschmar, H., Neumann, M., Lippa, C., Halliday, G., MacKenzie, J., Ravid, R., Dickson, D., Wszolek, Z. & 6 others, Iwatsubo, T., Pickering-Brown, S. M., Holton, J., Lees, A., Revesz, T. & Mann, D. M. A., Apr 2006, In : Acta Neuropathologica. 111, 4, p. 329-340 12 p.

Research output: Contribution to journalArticle

73 Scopus citations

Comparison of extent of tau pathology in patients with frontotemporal dementia with Parkinsonism linked to chromosome 17 (FTDP-17), frontotemporal lobar degeneration with Pick bodies and early onset Alzheimer's disease

Shiarli, A. M., Jennings, R., Shi, J., Bailey, K., Davidson, Y., Tian, J., Bigio, E. H., Ghetti, B., Murrell, J. R., Delisle, M. B., Mirra, S., Crain, B., Zolo, P., Arima, K., Iseki, E., Murayama, S., Kretzschmar, H., Neumann, M., Lippa, C., Halliday, G. & 8 others, MacKenzie, J., Khan, N., Ravid, R., Dickson, D., Wszolek, Z., Iwatsubo, T., Pickering-Brown, S. M. & Mann, D. M. A., Aug 2006, In : Neuropathology and Applied Neurobiology. 32, 4, p. 374-387 14 p.

Research output: Contribution to journalArticle

22 Scopus citations

Conversion to the amyotrophic lateral sclerosis phenotype is associated with intermolecular linked insoluble aggregates of SOD1 in mitochondria

Deng, H. X., Shi, Y., Furukawa, Y., Zhai, H., Fu, R., Liu, E., Gorrie, G. H., Khan, M. S., Hung, W. Y., Bigio, E. H., Lukas, T., Dal Canto, M. C., O'Halloran, T. V. & Siddique, T., May 2 2006, In : Proceedings of the National Academy of Sciences of the United States of America. 103, 18, p. 7142-7147 6 p.

Research output: Contribution to journalArticle

323 Scopus citations

Mutation analysis of patients with neuronal intermediate filament inclusion disease (NIFID)

Momeni, P., Cairns, N. J., Perry, R. H., Bigio, E. H., Gearing, M., Singleton, A. B. & Hardy, J., May 2006, In : Neurobiology of Aging. 27, 5, p. 778.e1-778.e6

Research output: Contribution to journalArticle

22 Scopus citations

Mutations in progranulin are a major cause of ubiquitin-positive frontotemporal lobar degeneration

Gass, J., Cannon, A., Mackenzie, I. R., Boeve, B., Baker, M., Adamson, J., Crook, R., Melquist, S., Kuntz, K., Petersen, R., Josephs, K., Pickering-Brown, S. M., Graff-Radford, N., Uitti, R., Dickson, D., Wszolek, Z., Gonzalez, J., Beach, T. G., Bigio, E., Johnson, N. & 10 others, Weintraub, S., Mesulam, M., White, C. L., Woodruff, B., Caselli, R., Hsiung, G. Y., Feldman, H., Knopman, D., Hutton, M. & Rademakers, R., Oct 15 2006, In : Human molecular genetics. 15, 20, p. 2988-3001 14 p.

Research output: Contribution to journalArticle

435 Scopus citations

Tau nitration occurs at tyrosine 29 in the fibrillar lesions of Alzheimer's disease and other tauopathies

Reynolds, M. R., Reyes, J. F., Fu, Y., Bigio, E. H., Guillozet-Bongaarts, A. L., Berry, R. W. & Binder, L. I., Oct 18 2006, In : Journal of Neuroscience. 26, 42, p. 10636-10645 10 p.

Research output: Contribution to journalArticle

96 Scopus citations

Tc-99m HMPAO SPECT in the differential diagnosis of the dementias with histopathologic confirmation

Bonte, F. J., Harris, T. S., Hynan, L. S., Bigio, E. H. & White, C. L., Jul 2006, In : Clinical nuclear medicine. 31, 7, p. 376-378 3 p.

Research output: Contribution to journalArticle

35 Scopus citations

West Nile virus encephalomyelitis with polio-like paralysis & nigral degeneration

Schafernak, K. T. & Bigio, E. H., Nov 2006, In : Canadian Journal of Neurological Sciences. 33, 4, p. 407-410 4 p.

Research output: Contribution to journalArticle

Open Access
12 Scopus citations
2007

Clinicopathologic correlation in PGRN mutations

Davion, S., Johnson, N., Weintraub, S., Mesulam, M-M., Engberg, A., Mishra, M., Baker, M., Adamson, J., Hutton, M., Rademakers, R. & Bigio, E. H., Jan 1 2007, In : Neurology. 69, 11, p. 1113-1121 9 p.

Research output: Contribution to journalArticle

45 Scopus citations

Gene expression analysis of frontotemporal lobar degeneration of the motor neuron disease type with ubiquitinated inclusions

Mishra, M., Paunesku, T., Woloschak, G. E., Siddique, T., Zhu, L., Lin, S., Greco, K. & Bigio, E. H., Jul 1 2007, In : Acta Neuropathologica. 114, 1, p. 81-94 14 p.

Research output: Contribution to journalArticle

58 Scopus citations