Eileen H Bigio

  • 22951 Citations
1989 …2020

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2016

Activation of HIPK2 Promotes ER Stress-Mediated Neurodegeneration in Amyotrophic Lateral Sclerosis

Lee, S., Shang, Y., Redmond, S. A., Urisman, A., Tang, A. A., Li, K. H., Burlingame, A. L., Pak, R. A., Jovičić, A., Gitler, A. D., Wang, J., Gray, N. S., Seeley, W. W., Siddique, T., Bigio, E. H., Lee, V. M. Y., Trojanowski, J. Q., Chan, J. R. & Huang, E. J., Jul 6 2016, In : Neuron. 91, 1, p. 41-55 15 p.

Research output: Contribution to journalArticle

41 Scopus citations

Aging-related tau astrogliopathy (ARTAG): harmonized evaluation strategy

Kovacs, G. G., Ferrer, I., Grinberg, L. T., Alafuzoff, I., Attems, J., Budka, H., Cairns, N. J., Crary, J. F., Duyckaerts, C., Ghetti, B., Halliday, G. M., Ironside, J. W., Love, S., Mackenzie, I. R., Munoz, D. G., Murray, M. E., Nelson, P. T., Takahashi, H., Trojanowski, J. Q., Ansorge, O. & 52 others, Arzberger, T., Baborie, A., Beach, T. G., Bieniek, K. F., Bigio, E. H., Bodi, I., Dugger, B. N., Feany, M., Gelpi, E., Gentleman, S. M., Giaccone, G., Hatanpaa, K. J., Heale, R., Hof, P. R., Hofer, M., Hortobágyi, T., Jellinger, K., Jicha, G. A., Ince, P., Kofler, J., Kövari, E., Kril, J. J., Mann, D. M., Matej, R., McKee, A. C., McLean, C., Milenkovic, I., Montine, T. J., Murayama, S., Lee, E. B., Rahimi, J., Rodriguez, R. D., Rozemüller, A., Schneider, J. A., Schultz, C., Seeley, W., Seilhean, D., Smith, C., Tagliavini, F., Takao, M., Thal, D. R., Toledo, J. B., Tolnay, M., Troncoso, J. C., Vinters, H. V., Weis, S., Wharton, S. B., White, C. L., Wisniewski, T., Woulfe, J. M., Yamada, M. & Dickson, D. W., Jan 1 2016, In : Acta Neuropathologica. 131, 1, p. 87-102 16 p.

Research output: Contribution to journalArticle

180 Scopus citations

Alzheimer's disease risk polymorphisms regulate gene expression in the ZCWPW1 and the CELF1 loci

Alzheimer's Disease Genetics Consortium (ADGC), Feb 2016, In : PloS one. 11, 2, e0148717.

Research output: Contribution to journalArticle

37 Scopus citations

A novel Alzheimer disease locus located near the gene encoding tau protein

Jun, G., Ibrahim-Verbaas, C. A., Vronskaya, M., Lambert, J. C., Chung, J., Naj, A. C., Kunkle, B. W., Wang, L. S., Bis, J. C., Bellenguez, C., Harold, D., Lunetta, K. L., Destefano, A. L., Grenier-Boley, B., Sims, R., Beecham, G. W., Smith, A. V., Chouraki, V., Hamilton-Nelson, K. L., Ikram, M. A. & 30 others, Fievet, N., Denning, N., Martin, E. R., Schmidt, H., Kamatani, Y., Dunstan, M. L., Valladares, O., Laza, A. R., Zelenika, D., Ramirez, A., Foroud, T. M., Choi, S. H., Boland, A., Becker, T., Kukull, W. A., Van Der Lee, S. J., Pasquier, F., Cruchaga, C., Beekly, D., Fitzpatrick, A. L., Hanon, O., Gill, M., Barber, R., Gudnason, V., Campion, D., Love, S., Bennett, D. A., Amin, N., Berr, C. & Tsolaki, M., Jan 1 2016, In : Molecular Psychiatry. 21, 1, p. 108-117 10 p.

Research output: Contribution to journalArticle

95 Scopus citations

Aphasic variant of Alzheimer disease

Rogalski, E., Sridhar, J., Rader, B., Martersteck, A., Chen, K., Cobia, D., Thompson, C. K., Weintraub, S., Bigio, E. H. & Mesulam, M. M., Sep 27 2016, In : Neurology. 87, 13, p. 1337-1343 7 p.

Research output: Contribution to journalArticle

24 Scopus citations

Assessment of the genetic variance of late-onset Alzheimer's disease

Alzheimer's Disease Genetics Consortium (ADGC), May 1 2016, In : Neurobiology of Aging. 41, p. 200.e13-200.e20

Research output: Contribution to journalArticle

Open Access
27 Scopus citations

Asymmetric pathology in primary progressive aphasia with progranulin mutations and TDP inclusions

Kim, G., Ahmadian, S. S., Peterson, M., Parton, Z., Memon, R., Weintraub, S., Rademaker, A., Bigio, E., Mesulam, M. M. & Geula, C., Feb 16 2016, In : Neurology. 86, 7, p. 627-636 10 p.

Research output: Contribution to journalArticle

17 Scopus citations

Multisite assessment of NIA-AA guidelines for the neuropathologic evaluation of Alzheimer's disease

Montine, T. J., Monsell, S. E., Beach, T. G., Bigio, E. H., Bu, Y., Cairns, N. J., Frosch, M., Henriksen, J., Kofler, J., Kukull, W. A., Lee, E. B., Nelson, P. T., Schantz, A. M., Schneider, J. A., Sonnen, J. A., Trojanowski, J. Q., Vinters, H. V., Zhou, X. H. & Hyman, B. T., Feb 1 2016, In : Alzheimer's and Dementia. 12, 2, p. 164-169 6 p.

Research output: Contribution to journalArticle

39 Scopus citations

Neuropathologic associations of learning and memory in primary progressive aphasia

Kielb, S., Cook, A., Wieneke, C., Rademaker, A., Bigio, E. H., Mesulam, M. M., Rogalski, E. & Weintraub, S., Jul 2016, In : JAMA Neurology. 73, 7, p. 846-852 7 p.

Research output: Contribution to journalArticle

6 Scopus citations

Neuropathology of autosomal dominant Alzheimer disease in the national Alzheimer coordinating center database

Ringman, J. M., Monsell, S., Ng, D. W., Zhou, Y., Nguyen, A., Coppola, G., Van Berlo, V., Mendez, M. F., Tung, S., Weintraub, S., Mesulam, M. M., Bigio, E. H., Gitelman, D. R., Fisher-Hubbard, A. O., Albin, R. L. & Vinters, H. V., Jan 1 2016, In : Journal of neuropathology and experimental neurology. 75, 3, p. 284-290 7 p.

Research output: Contribution to journalArticle

29 Scopus citations

Postmortem Adult Human Microglia Proliferate in Culture to High Passage and Maintain Their Response to Amyloid-β

Guo, L., Rezvanian, A., Kukreja, L., Hoveydai, R., Bigio, E. H., Mesulam, M. M., El Khoury, J. & Geula, C., 2016, In : Journal of Alzheimer's Disease. 54, 3, p. 1157-1167 11 p.

Research output: Contribution to journalArticle

2 Scopus citations

Progranulin Deficiency Promotes Circuit-Specific Synaptic Pruning by Microglia via Complement Activation

Lui, H., Zhang, J., Makinson, S. R., Cahill, M. K., Kelley, K. W., Huang, H. Y., Shang, Y., Oldham, M. C., Martens, L. H., Gao, F., Coppola, G., Sloan, S. A., Hsieh, C. L., Kim, C. C., Bigio, E. H., Weintraub, S., Mesulam, M. M., Rademakers, R., MacKenzie, I. R., Seeley, W. W. & 8 others, Karydas, A., Miller, B. L., Borroni, B., Ghidoni, R., Farese, R. V., Paz, J. T., Barres, B. A. & Huang, E. J., May 5 2016, In : Cell. 165, 4, p. 921-935 15 p.

Research output: Contribution to journalArticle

244 Scopus citations

Stillbirth: Correlations between brain injury and placental pathology

Ernst, L. M., Bit-Ivan, E. N., Miller, E. S., Minturn, L., Bigio, E. H. & Weese-Mayer, D. E., May 1 2016, In : Pediatric and Developmental Pathology. 19, 3, p. 237-243 7 p.

Research output: Contribution to journalArticle

6 Scopus citations
2015

A case of globular glial tauopathy presenting clinically as Alzheimer disease

SantaCruz, K. S., Rottunda, S. J., Meints, J. P., Bearer, E. L., Bigio, E. H. & McCarten, J. R., Mar 6 2015, In : Alzheimer Disease and Associated Disorders. 29, 1, p. 82-84 3 p.

Research output: Contribution to journalArticle

5 Scopus citations

Association of long runs of homozygosity with Alzheimer disease among African American individuals

Ghani, M., Reitz, C., Cheng, R., Vardarajan, B. N., Jun, G., Sato, C., Naj, A., Rajbhandary, R., Wang, L. S., Valladares, O., Lin, C. F., Larson, E. B., Graff-Radford, N. R., Evans, D., De Jager, P. L., Crane, P. K., Buxbaum, J. D., Murrell, J. R., Raj, T., Ertekin-Taner, N. & 153 others, Logue, M., Baldwin, C. T., Green, R. C., Barnes, L. L., Cantwell, L. B., Fallin, M. D., Go, R. C. P., Griffith, P. A., Obisesan, T. O., Manly, J. J., Lunetta, K. L., Kamboh, M. I., Lopez, O. L., Bennett, D. A., Hendrie, H., Hall, K. S., Goate, A. M., Byrd, G. S., Kukull, W. A., Foroud, T. M., Haines, J. L., Farrer, L. A., Pericak-Vance, M. A., Lee, J. H., Schellenberg, G. D., St. George-Hyslop, P., Mayeux, R., Rogaeva, E., Albert, M. S., Albin, R. L., Apostolova, L. G., Arnold, S. E., Barber, R., Barmada, M. M., Beach, T. G., Beecham, G. W., Beekly, D., Bigio, E. H., Bird, T. D., Blacker, D., Boeve, B. F., Bowen, J. D., Boxer, A., Burke, J. R., Cai, G., Cairns, N. J., Cao, C., Carlson, C. S., Carney, R. M., Carroll, S. L., Chui, H. C., Clark, D. G., Cribbs, D. H., Crocco, E. A., Cruchaga, C., DeCarli, C., DeKosky, S. T., Demirci, F. Y., Dick, M., Faber, K. M., Fallon, K. B., Ferris, S., Frosch, M. P., Galasko, D. R., Ganguli, M., Gearing, M., Geschwind, D. H., Ghetti, B., Gilbert, J. R., Gilman, S., Glass, J. D., Growdon, J. H., Hakonarson, H., Hamilton, R. L., Hamilton-Nelson, K. L., Haroutunian, V., Harrell, L. E., Honig, L. S., Hulette, C. M., Hyman, B. T., Jarvik, G. P., Jicha, G. A., Jin, L. W., Karydas, A., Kauwe, J. S. K., Kaye, J. A., Kim, R., Koo, E. H., Kowall, N. W., Kramer, J. H., Kramer, P., LaFerla, F. M., Lah, J. J., Lang-Walker, R., Leverenz, J. B., Levey, A. I., Li, G., Lieberman, A. P., Lyketsos, C. G., Mack, W. J., Marson, D. C., Martiniuk, F., Mash, D. C., Masliah, E., McCormick, W. C., McCurry, S. M., McDavid, A. N., McKee, A. C., Mesulam, M., Miller, B. L., Miller, C. A., Miller, J. W., Montine, T. J., Morris, J. C., Olichney, J. M., Parisi, J. E., Peskind, E., Petersen, R. C., Pierce, A., Poon, W. W., Potter, H., Quinn, J. F., Raj, A., Raskind, M., Reiman, E. M., Reisberg, B., Ringman, J. M., Roberson, E. D., Sano, M., Saykin, A. J., Schneider, J. A., Schneider, L. S., Seeley, W. W., Smith, A. G., Sonnen, J. A., Spina, S., Stern, R. A., Tanzi, R. E., Trojanowski, J. Q., Troncoso, J. C., Tsuang, D. W., Van Deerlin, V. M., Van Eldik, L. J., Vinters, H. V., Vonsattel, J. P., Weintraub, S., Welsh-Bohmer, K. A., Williamson, J., Woltjer, R. L., Wright, C. B., Younkin, S. G., Yu, C. E. & Yu, L., Nov 2015, In : JAMA Neurology. 72, 11, p. 1313-1323 11 p.

Research output: Contribution to journalArticle

18 Scopus citations

Associations between Potentially Modifiable Risk Factors and Alzheimer Disease: A Mendelian Randomization Study

Alzheimer’s Disease Genetics Consortium, The GERAD1 Consortium & EPIC-InterAct Consortium, Jun 1 2015, In : PLoS medicine. 12, 6, e1001841.

Research output: Contribution to journalArticle

74 Scopus citations

FUS Interacts with HSP60 to Promote Mitochondrial Damage

Deng, J., Yang, M., Chen, Y., Chen, X., Liu, J., Sun, S., Cheng, H., Li, Y., Bigio, E. H., Mesulam, M., Xu, Q., Du, S., Fushimi, K., Zhu, L. & Wu, J. Y., 2015, In : PLoS genetics. 11, 9, e1005357.

Research output: Contribution to journalArticle

61 Scopus citations

Genetically predicted body mass index and Alzheimer's disease-related phenotypes in three large samples: Mendelian randomization analyses

Adult Changes in Thought Study Investigators, Religious Orders Study/Memory and Aging Project Investigators & Alzheimer's Disease Genetics Consortium, Dec 1 2015, In : Alzheimer's and Dementia. 11, 12, p. 1439-1451 13 p.

Research output: Contribution to journalArticle

23 Scopus citations

Loss of calbindin-D28K is associated with the full range of tangle pathology within basal forebrain cholinergic neurons in Alzheimer's disease

Ahmadian, S. S., Rezvanian, A., Peterson, M., Weintraub, S., Bigio, E. H., Mesulam, M. M. & Geula, C., Dec 2015, In : Neurobiology of Aging. 36, 12, p. 3163-3170 8 p.

Research output: Contribution to journalArticle

18 Scopus citations

Morphometric and Histologic Substrates of Cingulate Integrity in Elders with Exceptional Memory Capacity

Gefen, T., Peterson, M., Papastefan, S. T., Martersteck, A., Whitney, K., Rademaker, A., Bigio, E. H., Weintraub, S., Rogalski, E., Mesulam, M. M. & Geula, C., Jan 28 2015, In : Journal of Neuroscience. 35, 4, p. 1781-1791 11 p.

Research output: Contribution to journalArticle

52 Scopus citations

Neuronal amyloid-β accumulation within cholinergic basal forebrain in ageing and Alzheimer's disease

Baker-Nigh, A., Vahedi, S., Davis, E. G., Weintraub, S., Bigio, E. H., Klein, W. L. & Geula, C., Jun 1 2015, In : Brain. 138, 6, p. 1722-1737 16 p.

Research output: Contribution to journalArticle

89 Scopus citations

Rarity of the alzheimer disease-protective APP A673T variant in the United States

National Institute on Aging-Late-Onset Alzheimer's Disease (NIA-LOAD) Family Study & Alzheimer's Disease Genetics Consortium, Feb 1 2015, In : JAMA Neurology. 72, 2, p. 209-216 8 p.

Research output: Contribution to journalArticle

21 Scopus citations
2014

Adult polyglucosan body disease with GBE1 haploinsufficiency and concomitant frontotemporal lobar degeneration

Bit-Ivan, E. N., Lee, K. H., Gitelman, D., Weintraub, S., Mesulam, M., Rademakers, R., Isaacs, A. M., Hatanpaa, K. J., White, C. L., Mao, Q., Akman, O., Dimauro, S. & Bigio, E. H., Oct 1 2014, In : Neuropathology and Applied Neurobiology. 40, 6, p. 778-782 5 p.

Research output: Contribution to journalArticle

4 Scopus citations

Alterations of Ca 2+ -responsive proteins within cholinergic neurons in aging and Alzheimer's disease

Riascos, D., Nicholas, A., Samaeekia, R., Yukhananov, R., Mesulam, M-M., Bigio, E. H., Weintraub, S., Guo, L. & Geula, C., Jun 1 2014, In : Neurobiology of Aging. 35, 6, p. 1325-1333 9 p.

Research output: Contribution to journalArticle

18 Scopus citations

An ALS-mutant TDP-43 neurotoxic peptide adopts an anti-parallel β-structure and induces TDP-43 redistribution

Zhu, L., Xu, M., Yang, M., Yang, Y., Li, Y., Deng, J., Ruan, L., Liu, J., Du, S., Liu, X., Feng, W., Fushimi, K., Bigio, E. H., Mesulam, M-M., Wang, C. & Wu, J., Dec 20 2014, In : Human molecular genetics. 23, 25, p. 6863-6877 15 p.

Research output: Contribution to journalArticle

29 Scopus citations

A novel GRN mutation (GRN c.708+6-+9delTGAG) in frontotemporal lobar degeneration with TDP-43-positive inclusions: Clinicopathologic report of 6 cases

Bit-Ivan, E. N., Suh, E., Shim, H. S., Weintraub, S., Hyman, B. T., Arnold, S. E., McCarty-Wood, E., Van Deerlin, V. M., Schneider, J. A., Trojanowski, J. Q., Frosch, M. P., Baker, M. C., Rademakers, R., Mesulam, M. & Bigio, E. H., May 2014, In : Journal of neuropathology and experimental neurology. 73, 5, p. 467-473 7 p.

Research output: Contribution to journalArticle

6 Scopus citations

Association between the prevalence of learning disabilities and primary progressive aphasia

Rogalski, E. J., Rademaker, A., Wieneke, C., Bigio, E. H., Weintraub, S. & Mesulam, M. M., Dec 1 2014, In : JAMA Neurology. 71, 12, p. 1576-1577 2 p.

Research output: Contribution to journalArticle

10 Scopus citations

Asymmetry and heterogeneity of Alzheimer's and frontotemporal pathology in primary progressive aphasia

Mesulam, M. M., Weintraub, S., Rogalski, E. J., Wieneke, C., Geula, C. & Bigio, E. H., Apr 2014, In : Brain. 137, 4, p. 1176-1192 17 p.

Research output: Contribution to journalArticle

161 Scopus citations

Ataxin-2 as potential disease modifier in C9ORF72 expansion carriers

van Blitterswijk, M., Mullen, B., Heckman, M. G., Baker, M. C., DeJesus-Hernandez, M., Brown, P. H., Murray, M. E., Hsiung, G. Y. R., Stewart, H., Karydas, A. M., Finger, E., Kertesz, A., Bigio, E. H., Weintraub, S., Mesulam, M., Hatanpaa, K. J., White, C. L., Neumann, M., Strong, M. J., Beach, T. G. & 17 others, Wszolek, Z. K., Lippa, C., Caselli, R., Petrucelli, L., Josephs, K. A., Parisi, J. E., Knopman, D. S., Petersen, R. C., Mackenzie, I. R., Seeley, W. W., Grinberg, L. T., Miller, B. L., Boylan, K. B., Graff-Radford, N. R., Boeve, B. F., Dickson, D. W. & Rademakers, R., Oct 2014, In : Neurobiology of Aging. 35, 10, p. 2421.e13-2421.e17

Research output: Contribution to journalArticle

61 Scopus citations

Clinicopathologic report of ocular involvement in ALS patients with C9orf72 mutation

Fawzi, A. A., Simonett, J. M., Purta, P., Moss, H. E., Lowry, J. L., Deng, H. X., Siddique, N., Sufit, R., Bigio, E. H., Volpe, N. J. & Siddique, T., Dec 1 2014, In : Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration. 15, 7-8, p. 569-580 12 p.

Research output: Contribution to journalArticle

14 Scopus citations

Dendritic spinopathy in transgenic mice expressing ALS/dementia-linked mutant UBQLN2

Gorrie, G. H., Fecto, F., Radzicki, D., Weiss, C., Shi, Y., Dong, H., Zhai, H., Fu, R., Liu, E., Li, S., Arrat, H., Bigio, E. H., Disterhoft, J. F., Martina, M., Mugnaini, E., Siddique, T., Deng, H. X. & Russell, D. W., Oct 7 2014, In : Proceedings of the National Academy of Sciences of the United States of America. 111, 40, p. 14524-14529 6 p.

Research output: Contribution to journalArticle

32 Scopus citations

Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: A genome-wide association study

Alzheimer Disease Genetics Consortium, Nov 1 2014, In : JAMA Neurology. 71, 11, p. 1394-1404 11 p.

Research output: Contribution to journalArticle

98 Scopus citations

Genetic modifiers in carriers of repeat expansions in the C9ORF72 gene

van Blitterswijk, M., Mullen, B., Wojtas, A., Heckman, M. G., Diehl, N. N., Baker, M. C., DeJesus-Hernandez, M., Brown, P. H., Murray, M. E., Hsiung, G. Y. R., Stewart, H., Karydas, A. M., Finger, E., Kertesz, A., Bigio, E. H., Weintraub, S., Mesulam, M., Hatanpaa, K. J., White, C. L., Neumann, M. & 19 others, Strong, M. J., Beach, T. G., Wszolek, Z. K., Lippa, C., Caselli, R., Petrucelli, L., Josephs, K. A., Parisi, J. E., Knopman, D. S., Petersen, R. C., Mackenzie, I. R., Seeley, W. W., Grinberg, L. T., Miller, B. L., Boylan, K. B., Graff-Radford, N. R., Boeve, B. F., Dickson, D. W. & Rademakers, R., Jan 1 2014, In : Molecular neurodegeneration. 9, 1 p.

Research output: Contribution to journalArticle

41 Scopus citations

Primary age-related tauopathy (PART): a common pathology associated with human aging

Crary, J. F., Trojanowski, J. Q., Schneider, J. A., Abisambra, J. F., Abner, E. L., Alafuzoff, I., Arnold, S. E., Attems, J., Beach, T. G., Bigio, E. H., Cairns, N. J., Dickson, D. W., Gearing, M., Grinberg, L. T., Hof, P. R., Hyman, B. T., Jellinger, K., Jicha, G. A., Kovacs, G. G., Knopman, D. S. & 23 others, Kofler, J., Kukull, W. A., Mackenzie, I. R., Masliah, E., McKee, A., Montine, T. J., Murray, M. E., Neltner, J. H., Santa-Maria, I., Seeley, W. W., Serrano-Pozo, A., Shelanski, M. L., Stein, T., Takao, M., Thal, D. R., Toledo, J. B., Troncoso, J. C., Vonsattel, J. P., White, C. L., Wisniewski, T., Woltjer, R. L., Yamada, M. & Nelson, P. T., Nov 14 2014, In : Acta Neuropathologica. 128, 6, p. 755-766 12 p.

Research output: Contribution to journalArticle

550 Scopus citations

TMEM106B protects C9ORF72 expansion carriers against frontotemporal dementia

Van Blitterswijk, M., Mullen, B., Nicholson, A. M., Bieniek, K. F., Heckman, M. G., Baker, M. C., Dejesus-Hernandez, M., Finch, N. A., Brown, P. H., Murray, M. E., Hsiung, G. Y. R., Stewart, H., Karydas, A. M., Finger, E., Kertesz, A., Bigio, E. H., Weintraub, S., Mesulam, M., Hatanpaa, K. J., White, C. L. & 19 others, Strong, M. J., Beach, T. G., Wszolek, Z. K., Lippa, C., Caselli, R., Petrucelli, L., Josephs, K. A., Parisi, J. E., Knopman, D. S., Petersen, R. C., Mackenzie, I. R., Seeley, W. W., Grinberg, L. T., Miller, B. L., Boylan, K. B., Graff-Radford, N. R., Boeve, B. F., Dickson, D. W. & Rademakers, R., Mar 1 2014, In : Acta Neuropathologica. 127, 3, p. 397-406 10 p.

Research output: Contribution to journalArticle

86 Scopus citations
2013

C9ORF72 repeat expansions in cases with previously identified pathogenic mutations

Van Blitterswijk, M., Baker, M. C., Hernandez, M., Ghidoni, R., Benussi, L., Finger, E., Hsiung, G. Y. R., Kelley, B. J., Murray, M. E., Rutherford, N. J., Brown, P. E., Ravenscroft, T., Mullen, B., Ash, P. E. A., Bieniek, K. F., Hatanpaa, K. J., Karydas, A., Wood, E. M. C., Coppola, G., Bigio, E. H. & 22 others, Lippa, C., Strong, M. J., Beach, T. G., Knopman, D. S., Huey, E. D., Mesulam, M., Bird, T., White, C. L., Kertesz, A., Geschwind, D. H., Van Deerlin, V. M., Petersen, R. C., Binetti, G., Miller, B. L., Petrucelli, L., Wszolek, Z. K., Boylan, K. B., Graff-Radford, N. R., MacKenzie, I. R., Boeve, B. F., Dickson, D. W. & Rademakers, R., Oct 8 2013, In : Neurology. 81, 15, p. 1332-1341 10 p.

Research output: Contribution to journalArticle

66 Scopus citations

Frontotemporal lobar degeneration with TDP-43 proteinopathy and chromosome 9p repeat expansion in C9ORF72: Clinicopathologic correlation

Bigio, E. H., Weintraub, S., Rademakers, R., Baker, M., Ahmadian, S. S., Rademaker, A., Weitner, B. B., Mao, Q., Lee, K. H., Mishra, M., Ganti, R. A. & Mesulam, M. M., Apr 2013, In : Neuropathology. 33, 2, p. 122-133 12 p.

Research output: Contribution to journalArticle

27 Scopus citations

Globular glial tauopathies (GGT): Consensus recommendations

Ahmed, Z., Bigio, E. H., Budka, H., Dickson, D. W., Ferrer, I., Ghetti, B., Giaccone, G., Hatanpaa, K. J., Holton, J. L., Josephs, K. A., Powers, J., Spina, S., Takahashi, H., White, C. L., Revesz, T. & Kovacs, G. G., 2013, In : Acta Neuropathologica. 126, 4, p. 537-544 8 p.

Research output: Contribution to journalArticle

106 Scopus citations

Making the diagnosis of frontotemporal lobar degeneration

Bigio, E. H., Mar 2013, In : Archives of Pathology and Laboratory Medicine. 137, 3, p. 314-325 12 p.

Research output: Contribution to journalArticle

18 Scopus citations

Nuclear carrier and RNA-binding proteins in frontotemporal lobar degeneration associated with fused in sarcoma (FUS) pathological changes

Davidson, Y. S., Robinson, A. C., Hu, Q., Mishra, M., Baborie, A., Jaros, E., Perry, R. H., Cairns, N. J., Richardson, A., Gerhard, A., Neary, D., Snowden, J. S., Bigio, E. H. & Mann, D. M. A., Feb 2013, In : Neuropathology and Applied Neurobiology. 39, 2, p. 157-165 9 p.

Research output: Contribution to journalArticle

20 Scopus citations

Pineal chordoid meningioma complicated by repetitive hemorrhage during pregnancy: Case report and literature review

Lee, K. H., Lall, R. R., Chandler, J. P., Bigio, E. H. & Mao, Q., Apr 1 2013, In : Neuropathology. 33, 2, p. 192-198 7 p.

Research output: Contribution to journalArticle

10 Scopus citations

TREM2 in neurodegeneration: Evidence for association of the p.R47H variant with frontotemporal dementia and Parkinson's disease

Rayaprolu, S., Mullen, B., Baker, M., Lynch, T., Finger, E., Seeley, W. W., Hatanpaa, K. J., Lomen-Hoerth, C., Kertesz, A., Bigio, E. H., Lippa, C., Josephs, K. A., Knopman, D. S., White, C. L., Caselli, R., Mackenzie, I. R., Miller, B. L., Boczarska-Jedynak, M., Opala, G., Krygowska-Wajs, A. & 13 others, Barcikowska, M., Younkin, S. G., Petersen, R. C., Ertekin-Taner, N., Uitti, R. J., Meschia, J. F., Boylan, K. B., Boeve, B. F., Graff-Radford, N. R., Wszolek, Z. K., Dickson, D. W., Rademakers, R. & Ross, O. A., 2013, In : Molecular neurodegeneration. 8, 1, 19.

Research output: Contribution to journalArticle

212 Scopus citations
51 Scopus citations
2012

Clinically concordant variations of Alzheimer pathology in aphasic versus amnestic dementia

Gefen, T., Gasho, K., Rademaker, A., Lalehzari, M., Weintraub, S., Rogalski, E., Wieneke, C., Bigio, E., Geula, C. & Mesulam, M. M., May 2012, In : Brain. 135, 5, p. 1554-1565 12 p.

Research output: Contribution to journalArticle

81 Scopus citations

Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis

Whitcomb, D. C., LaRusch, J., Krasinskas, A. M., Klei, L., Smith, J. P., Brand, R. E., Neoptolemos, J. P., Lerch, M. M., Tector, M., Sandhu, B. S., Guda, N. M., Orlichenko, L., Alkaade, S., Amann, S. T., Anderson, M. A., Baillie, J., Banks, P. A., Conwell, D., Coté, G. A., Cotton, P. B. & 30 others, DiSario, J., Farrer, L. A., Forsmark, C. E., Johnstone, M., Gardner, T. B., Gelrud, A., Greenhalf, W., Haines, J. L., Hartman, D. J., Hawes, R. A., Lawrence, C., Lewis, M., Mayerle, J., Mayeux, R., Melhem, N. M., Money, M. E., Muniraj, T., Papachristou, G. I., Pericak-Vance, M. A., Romagnuolo, J., Schellenberg, G. D., Sherman, S., Simon, P., Singh, V. P., Slivka, A., Stolz, D., Sutton, R., Weiss, F. U., Wilcox, C. M. & Zarnescu, N. O., Dec 2012, In : Nature Genetics. 44, 12, p. 1349-1354 6 p.

Research output: Contribution to journalArticle

168 Scopus citations

Evidence for a role of the rare p.A152T variant in mapt in increasing the risk for FTD-spectrum and Alzheimer's diseases

Coppola, G., Chinnathambi, S., Lee, J. J. Y., Dombroski, B. A., Baker, M. C., Soto-ortolaza, A. I., Lee, S. E., Klein, E., Huang, A. Y., Sears, R., Lane, J. R., Karydas, A. M., Kenet, R. O., Biernat, J., Wang, L. S., Cotman, C. W., Decarli, C. S., Levey, A. I., Ringman, J. M., Mendez, M. F. & 30 others, Chui, H. C., Le ber, I., Brice, A., Lupton, M. K., Preza, E., Lovestone, S., Powell, J., Graff-radford, N., Petersen, R. C., Boeve, B. F., Lippa, C. F., Bigio, E. H., Mackenzie, I., Finger, E., Kertesz, A., Caselli, R. J., Gearing, M., Juncos, J. L., Ghetti, B., Spina, S., Bordelon, Y. M., Tourtellotte, W. W., Frosch, M. P., Vonsattel, J. P. G., Zarow, C., Beach, T. G., Albin, R. L., Lieberman, A. P., Lee, V. M. & Trojanowski, J. Q., Aug 2012, In : Human molecular genetics. 21, 15, p. 3500-3512 13 p.

Research output: Contribution to journalArticle

145 Scopus citations

Length of normal alleles of C9ORF72 GGGGCC repeat do not influence disease phenotype

Rutherford, N. J., Heckman, M. G., DeJesus-Hernandez, M., Baker, M. C., Soto-Ortolaza, A. I., Rayaprolu, S., Stewart, H., Finger, E., Volkening, K., Seeley, W. W., Hatanpaa, K. J., Lomen-Hoerth, C., Kertesz, A., Bigio, E. H., Lippa, C., Knopman, D. S., Kretzschmar, H. A., Neumann, M., Caselli, R. J., White, C. L. & 12 others, Mackenzie, I. R., Petersen, R. C., Strong, M. J., Miller, B. L., Boeve, B. F., Uitti, R. J., Boylan, K. B., Wszolek, Z. K., Graff-Radford, N. R., Dickson, D. W., Ross, O. A. & Rademakers, R., Dec 2012, In : Neurobiology of Aging. 33, 12, p. 2950.e5-2950.e7

Research output: Contribution to journalArticle

67 Scopus citations

Lymphomatosis cerebri presenting with orthostatic hypotension, anorexia, and paraparesis

Keswani, A., Bigio, E. & Grimm, S., Sep 1 2012, In : Journal of Neuro-Oncology. 109, 3, p. 581-586 6 p.

Research output: Contribution to journalArticle

15 Scopus citations

National institute on aging-Alzheimer's association guidelines for the neuropathologic assessment of Alzheimer's disease: A practical approach

Montine, T. J., Phelps, C. H., Beach, T. G., Bigio, E. H., Cairns, N. J., Dickson, D. W., Duyckaerts, C., Frosch, M. P., Masliah, E., Mirra, S. S., Nelson, P. T., Schneider, J. A., Thal, D. R., Trojanowski, J. Q., Vinters, H. V. & Hyman, B. T., Jan 1 2012, In : Acta Neuropathologica. 123, 1, p. 1-11 11 p.

Research output: Contribution to journalArticle

1005 Scopus citations

National Institute on Aging-Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease

Hyman, B. T., Phelps, C. H., Beach, T. G., Bigio, E. H., Cairns, N. J., Carrillo, M. C., Dickson, D. W., Duyckaerts, C., Frosch, M. P., Masliah, E., Mirra, S. S., Nelson, P. T., Schneider, J. A., Thal, D. R., Thies, B., Trojanowski, J. Q., Vinters, H. V. & Montine, T. J., Jan 1 2012, In : Alzheimer's and Dementia. 8, 1, p. 1-13 13 p.

Research output: Contribution to journalArticle

1027 Scopus citations