Grants per year
Personal profile
Research Interests
I am interested in the causes and treatment of heart failure in children, both congenital and acquired--this includes myocarditis, Single ventricle patients and all types of cardiomyopathy. I believe we can make significant improvements in the long term outcomes of young patients with cardiomyopathy, in terms of their quality of life, and survival. As the medical director of transplant/heart failure, I am committed to studying the clinical aspects of pediatric heart transplantation, particularly in improving the late outcomes that impact on survival, such as allograft vasculopathy and late rejection. In addition, i am interested in the succesful transition of adolescents/young adults to adult centers. I have a long standing interest in Kawasaki Disease, which overlaps with my research interest in coronary abnornailties in transplanted patients and in congenital coronary anomalies.
Certifications and Licenses
Pediatrics | |
Pediatric Cardiology |
Training Experience
1986 | Residency, Northwestern University, McGaw Medical Center (Children’s Memorial Hospital) |
1988 | Fellowship, Children's Hospital of Pittsburgh |
Education/Academic qualification
Medicine, MD, Northwestern University
… → 1983
Research interests keywords
- Cardiomyopathy
- Congenital Heart Disease
- Heart Transplantation
- Pediatric Cardiology
- Sudden Cardiac Death
- Transplant Pathology
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Collaborations and top research areas from the last five years
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Comprehensive Cardiac Structure-Function Analysis in Heart Transplantation
Carr, J. (PD/PI), Carr, J. (PD/PI), Markl, M. (PD/PI), Markl, M. (PD/PI), Elbaz, M. (Co-Investigator), Elbaz, M. (Co-Investigator), Ghafourian, K. (Co-Investigator), Ghafourian, K. (Co-Investigator), Lee, D. C. (Co-Investigator), Lee, D. C. (Co-Investigator), Lin, K. (Co-Investigator), Lomasney, J. W. (Co-Investigator), Lomasney, J. W. (Co-Investigator), Ragin, A. (Co-Investigator), Ragin, A. (Co-Investigator), Rigolin, V. H. (Co-Investigator), Rigolin, V. H. (Co-Investigator), Thomas, J. D. (Co-Investigator), Thomas, J. D. (Co-Investigator), Vorovich, E. E. (Co-Investigator), Vorovich, E. E. (Co-Investigator), Yancy, C. W. (Co-Investigator), Yancy, C. W. (Co-Investigator), Pahl, E. (Other) & Pahl, E. (Other)
National Heart, Lung, and Blood Institute
7/1/21 → 4/30/26
Project: Research project
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Multicenter Randomized Trial of Everolimus in Pediatric Heart Transplantation
Pahl, E. (PD/PI)
Children's Hospital Boston, Department of Defense
9/15/17 → 9/14/22
Project: Research project
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Multicenter Randomized Trial of Everolimus in Pediatric Heart Transplantation
Pahl, E. (PD/PI)
Children's Hospital Boston, Department of Defense
9/15/17 → 9/14/22
Project: Research project
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Multicenter Randomized Trial of Everolimus in Pediatric Heart Transplantation
Pahl, E. (PD/PI)
Children's Hospital Boston, Department of Defense
9/15/17 → 9/14/22
Project: Research project
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Quantitative Detection of Circulating Donor-Specific DNA in Heart Transplant Recipients
Pahl, E. (PD/PI)
4/4/17 → 3/31/20
Project: Research project
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Cardiac imaging and biomarkers for assessing myocardial fibrosis in children with hypertrophic cardiomyopathy
Kirmani, S., Woodard, P. K., Shi, L., Hamza, T. H., Canter, C. E., Colan, S. D., Pahl, E., Towbin, J. A., Webber, S. A., Rossano, J. W., Everitt, M. D., Molina, K. M., Kantor, P. F., Jefferies, J. L., Feingold, B., Addonizio, L. J., Ware, S. M., Chung, W. K., Ballweg, J. A. & Lee, T. M. & 8 others, , Oct 2023, In: American heart journal. 264, p. 153-162 10 p.Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
Cardiac Remodeling in Subclinical Hypertrophic Cardiomyopathy The VANISH Randomized Clinical Trial
Valsartan for Attenuating Disease Evolution in Early Sarcomeric Hypertrophic Cardiomyopathy (VANISH) Investigators, Nov 8 2023, In: JAMA cardiology. 8, 11, p. 1083-1089 7 p.Research output: Contribution to journal › Article › peer-review
9 Scopus citations -
Donor-specific antibodies after heart transplantation for Fontan-associated protein-losing enteropathy
Magnetta, D. A., Hoch, V. L., Pinelli, D., Monge, M., Pahl, E. & Thrush, P. T., Aug 2023, In: Pediatric transplantation. 27, 5, e14458.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
The teammate trial: Study design and rationale tacrolimus and everolimus against tacrolimus and MMF in pediatric heart transplantation using the major adverse transplant event (MATE) score
Almond, C. S., Sleeper, L. A., Rossano, J. W., Bock, M. J., Pahl, E., Auerbach, S., Lal, A., Hollander, S. A., Miyamoto, S. D., Castleberry, C., Lee, J., Barkoff, L. M., Gonzales, S., Klein, G. & Daly, K. P., Jun 2023, In: American heart journal. 260, p. 100-112 13 p.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
Transforming Growth Factor-β Analysis of the VANISH Trial Cohort
Kim, Y., Mastali, M., Van Eyk, J. E., Orav, E. J., Vissing, C. R., Day, S. M., Axelsson Raja, A., Russell, M. W., Zahka, K., Lever, H. M., Pereira, A. C., Murphy, A. M., Canter, C., Bach, R. G., Wheeler, M. T., Rossano, J. W., Owens, A. T., Bundgaard, H., Benson, L. & Mestroni, L. & 12 others, , Apr 1 2023, In: Circulation: Heart Failure. 16, 4, p. E010314Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations
Datasets
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Cardiovascular health in pediatric heart transplant patients
Bogle, C. (Creator), Marma Perak, A. (Creator), Wilkens, S. J. (Creator), Aljiffry, A. (Creator), Rychlik, K. (Creator), Costello, J. M. (Creator), Lloyd-Jones, D. M. (Creator) & Pahl, E. (Creator), figshare, 2022
DOI: 10.6084/m9.figshare.c.5927619, https://springernature.figshare.com/collections/Cardiovascular_health_in_pediatric_heart_transplant_patients/5927619
Dataset