Elias Gounaris

  • 1184 Citations
1982 …2019

Research output per year

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Research Output

  • 1184 Citations
  • 25 Article
  • 2 Review article
  • 1 Chapter
  • 1 Comment/debate
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Article
2018

Validation of near infrared fluorescence (NIRF) probes in vivo with dual laser NIRF endoscope

Shrivastav, M., Gounaris, E., Khan, M. W., Ko, J., Ryu, S. H., Bogyo, M., Larson, A., Barret, T. A. & Bentrem, D. J., Nov 2018, In : PloS one. 13, 11, e0206568.

Research output: Contribution to journalArticle

2 Scopus citations
2017

Epithelial TNF receptor signaling promotes mucosal repair in inflammatory bowel disease

Bradford, E. M., Ryu, S. H., Singh, A. P., Lee, G., Goretsky, T., Sinh, P., Williams, D. B., Cloud, A. L., Gounaris, E., Patel, V., Lamping, O. F., Lynch, E. B., Moyer, M. P., De Plaen, I. G., Shealy, D. J., Yang, G. Y. & Barrett, T. A., Sep 1 2017, In : Journal of Immunology. 199, 5, p. 1886-1897 12 p.

Research output: Contribution to journalArticle

28 Scopus citations
2016

Near-infrared fluorescence endoscopy to detect dysplastic lesions in the mouse colon

Gounaris, E., Ishihara, Y., Shrivastrav, M., Bentrem, D. & Barrett, T. A., Jan 1 2016, In : Methods in Molecular Biology. 1422, p. 137-147 11 p.

Research output: Contribution to journalArticle

5 Scopus citations
2015

Ablation of 5-lipoxygenase mitigates pancreatic lesion development

Knab, L. M., Schultz, M., Principe, D. R., Mascarinas, W. E., Gounaris, E., Munshi, H. G., Grippo, P. J. & Bentrem, D. J., Apr 1 2015, In : Journal of Surgical Research. 194, 2, p. 481-487 7 p.

Research output: Contribution to journalArticle

11 Scopus citations

Zileuton, 5-lipoxygenase inhibitor, acts as a chemopreventive agent in intestinal polyposis, by modulating polyp and systemic inflammation

Gounaris, E., Heiferman, M. J., Heiferman, J. R., Shrivastav, M., Vitello, D., Blatner, N. R., Knab, L. M., Phillips, J. D., Cheon, E. C., Grippo, P. J., Khazaie, K., Munshi, H. G. & Bentrem, D. J., Mar 6 2015, In : PloS one. 10, 3, e0121402.

Research output: Contribution to journalArticle

24 Scopus citations
2014

Autophagy is a survival mechanism of acute myelogenous leukemia precursors during dual mTORC2/mTORC1 targeting

Altman, J. K., Szilard, A., Goussetis, D. J., Sassano, A., Colamonici, M., Gounaris, E., Frankfurt, O., Giles, F. J., Eklund, E. A., Beauchamp, E. M. & Platanias, L. C., May 1 2014, In : Clinical Cancer Research. 20, 9, p. 2400-2409 10 p.

Research output: Contribution to journalArticle

46 Scopus citations
2013

BCR-ABL1-induced leukemogenesis and autophagic targeting by arsenic trioxide

Goussetis, D. J., Gounaris, E. & Platanias, L. C., Jan 2013, In : Autophagy. 9, 1, p. 93-94 2 p.

Research output: Contribution to journalArticle

11 Scopus citations

PI3K/AKT signaling is essential for communication between tissue-infiltrating mast cells, macrophages, and epithelial cells in colitis-induced cancer

Khan, M. W., Keshavarzian, A., Gounaris, E., Melson, J. E., Cheon, E. C., Blatner, N. R., Chen, Z. E., Tsai, F. N., Lee, G., Ryu, H., Barrett, T. A., Bentrem, D. J., Beckhove, P. & Khazaie, K., May 1 2013, In : Clinical Cancer Research. 19, 9, p. 2342-2354 13 p.

Research output: Contribution to journalArticle

38 Scopus citations
2012

Autophagic degradation of the BCR-ABL oncoprotein and generation of antileukemic responses by arsenic trioxide

Goussetis, D. J., Gounaris, E., Wu, E. J., Vakana, E., Sharma, B., Bogyo, M., Altman, J. K. & Platanias, L. C., Oct 25 2012, In : Blood. 120, 17, p. 3555-3562 8 p.

Research output: Contribution to journalArticle

83 Scopus citations

Modulating intestinal immune responses by lipoteichoic acid-deficient Lactobacillus acidophilus

Khan, M. W., Zadeh, M., Bere, P., Gounaris, E., Owen, J., Klaenhammer, T. & Mohamadzadeh, M., Feb 1 2012, In : Immunotherapy. 4, 2, p. 151-161 11 p.

Research output: Contribution to journalArticle

17 Scopus citations

Tpl2 ablation promotes intestinal inflammation and tumorigenesis in Apcmin mice by inhibiting IL-10 secretion and regulatory T-cell generation

Serebrennikova, O. B., Tsatsanis, C., Mao, C., Gounaris, E., Ren, W., Siracusa, L. D., Eliopoulos, A. G., Khazaie, K. & Tsichlis, P. N., May 1 2012, In : Proceedings of the National Academy of Sciences of the United States of America. 109, 18, p. E1082-E1091

Research output: Contribution to journalArticle

36 Scopus citations
2011

Mast cell 5-lipoxygenase activity promotes intestinal polyposis in APC Δ468 mice

Cheon, E. C., Khazaie, K., Khan, M. W., Strouch, M. J., Krantz, S. B., Phillips, J., Blatner, N. R., Hix, L. M., Zhang, M., Dennis, K. L., Salabat, M. R., Heiferman, M., Grippo, P. J., Munshi, H. G., Gounaris, E. & Bentrem, D. J., Mar 1 2011, In : Cancer Research. 71, 5, p. 1627-1636 10 p.

Research output: Contribution to journalArticle

55 Scopus citations

The significant role of mast cells in cancer

Khazaie, K., Blatner, N. R., Khan, M. W., Gounari, F., Gounaris, E., Dennis, K., Bonertz, A., Tsai, F. N., Strouch, M. J., Cheon, E., Phillips, J. D., Beckhove, P. & Bentrem, D. J., Mar 2011, In : Cancer and Metastasis Reviews. 30, 1, p. 45-60 16 p.

Research output: Contribution to journalArticle

129 Scopus citations
2010

Crosstalk between mast cells and pancreatic cancer cells contributes to pancreatic tumor progression

Strouch, M. J., Cheon, E. C., Salabat, M. R., Krantz, S. B., Gounaris, E., Melstrom, L. G., Dangi-Garimella, S., Wang, E., Munshi, H. G., Khazaie, K. & Bentrem, D. J., Apr 15 2010, In : Clinical Cancer Research. 16, 8, p. 2257-2265 9 p.

Research output: Contribution to journalArticle

113 Scopus citations
2009

T-regulatory cells shift from a protective anti-inflammatory to a cancer-promoting proinflammatory phenotype in polyposis

Gounaris, E., Blatner, N. R., Dennis, K., Magnusson, F., Gurish, M. F., Strom, T. B., Beckhove, P., Gounari, F. & Khazaie, K., Jul 1 2009, In : Cancer Research. 69, 13, p. 5490-5497 8 p.

Research output: Contribution to journalArticle

130 Scopus citations
2008

Live imaging of cysteine-cathepsin activity reveals dynamics of focal inflammation, angiogenesis, and polyp growth

Gounaris, E., Tung, C. H., Restaino, C., Maehr, R., Kohler, R., Joyce, J. A., Plough, H. L., Barrett, T. A., Weissleder, R. & Khazaie, K., Aug 13 2008, In : PloS one. 3, 8, e2916.

Research output: Contribution to journalArticle

85 Scopus citations
2007

Mast cells are an essential hematopoietic component for polyp development

Gounaris, E., Erdman, S. E., Restaino, C., Gurish, M. F., Friend, D. S., Gounari, F., Lee, D. M., Zhang, G., Glickman, J. N., Shin, K., Rao, V. P., Poutahidis, T., Weissleder, R., McNagny, K. M. & Khazaie, K., Dec 11 2007, In : Proceedings of the National Academy of Sciences of the United States of America. 104, 50, p. 19977-19982 6 p.

Research output: Contribution to journalArticle

189 Scopus citations
2005

Loss of adenomatous polyposis coli gene function disrupts thymic development

Gounari, F., Chang, R., Cowan, J., Guo, Z., Dose, M., Gounaris, E. & Khazaie, K., Aug 1 2005, In : Nature Immunology. 6, 8, p. 800-809 10 p.

Research output: Contribution to journalArticle

79 Scopus citations
2004
19 Scopus citations

Metabolism of 2-phenylethylamine and phenylacetaldehyde by precision-cut guinea pig fresh liver slices

Panoutsopoulos, G. I., Kouretas, D., Gounaris, E. G. & Beedham, C., Jan 1 2004, In : European Journal of Drug Metabolism and Pharmacokinetics. 29, 2, p. 111-118 8 p.

Research output: Contribution to journalArticle

21 Scopus citations
1994

Purification and kinetic properties of phosphofructokinase from Rana ridibunda erythrocytes

Kaloyianni, M., Kotinis, K. & Gounaris, E. G., Jan 1 1994, In : Comparative Biochemistry and Physiology -- Part B: Biochemistry and. 107, 3, p. 479-487 9 p.

Research output: Contribution to journalArticle

2 Scopus citations
1991

Mechanisms responsible for the limited lifespan and immortal phenotypes in cultured mammalian cells

Rosenberger, R. F., Gounaris, E. & Kolettas, E., Feb 7 1991, In : Journal of Theoretical Biology. 148, 3, p. 383-392 10 p.

Research output: Contribution to journalArticle

17 Scopus citations
1990

Biochemical and physiological responses of Tetrahymena pyriformis during adaptation to high glycerol concentrations

Gounaris, E. G., Bardopoulou, H. & Kotinis, K. K., Oct 15 1990, In : Microbiologica. 13, 3, p. 239-246 8 p.

Research output: Contribution to journalArticle

Physiological response of Tetrahymena pyriformis during adaptation to elevated external salinity

Gounaris, E. G. & Kotinis, K. K., Apr 9 1990, In : Microbiologica. 13, 1, p. 73-76 4 p.

Research output: Contribution to journalArticle

1 Scopus citations
1982

Separation and partial characterization of the nucleolytic activities of mouse liver ribosomes.

Gounaris, E. G. & Georgatsos, J. G., Dec 1 1982, In : Progress in Clinical and Biological Research. 102 Pt C, p. 153-162 10 p.

Research output: Contribution to journalArticle

2 Scopus citations