Elizabeth M McNally

  • 12249 Citations
1983 …2024
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Research Output 1983 2020

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Review article
2019

Better living through peptide-conjugated chemistry: Next-generation antisense oligonucleotides

McNally, E. M. & Leverson, B. D., Nov 1 2019, In : Journal of Clinical Investigation. 129, 11, p. 4570-4571 2 p.

Research output: Contribution to journalReview article

Cell-Penetrating Peptides
Neuromuscular Diseases
Antisense Oligonucleotides
Spinal Muscular Atrophy
Myotonic Dystrophy
2018
2 Citations (Scopus)

Gene Editing and Gene-Based Therapeutics for Cardiomyopathies

Ohiri, J. C. & McNally, E. M., Apr 1 2018, In : Heart Failure Clinics. 14, 2, p. 179-188 10 p.

Research output: Contribution to journalReview article

Cardiomyopathies
Genes
Mutation
Duchenne Muscular Dystrophy
Antisense Oligonucleotides
5 Citations (Scopus)

Non-Glycanated Biglycan and LTBP4: Leveraging the extracellular matrix for Duchenne Muscular Dystrophy therapeutics

Fallon, J. R. & McNally, E. M., Aug 2018, In : Matrix Biology. 68-69, p. 616-627 12 p.

Research output: Contribution to journalReview article

Biglycan
Duchenne Muscular Dystrophy
Extracellular Matrix
Carrier Proteins
Dystrophin
2017
102 Citations (Scopus)

Dilated cardiomyopathy: Genetic determinants and mechanisms

McNally, E. M. & Mestroni, L., Sep 1 2017, In : Circulation research. 121, 7, p. 731-748 18 p.

Research output: Contribution to journalReview article

Dilated Cardiomyopathy
Genetic Testing
Cardiac Arrhythmias
Cardiomyopathies
Genes
16 Citations (Scopus)

Muscle cell communication in development and repair

Demonbreun, A. R. & McNally, E. M., Jun 1 2017, In : Current Opinion in Pharmacology. 34, p. 7-14 8 p.

Research output: Contribution to journalReview article

Cell Communication
Muscle Cells
Exosomes
Regeneration
Muscles
12 Citations (Scopus)

Outside in: The matrix as a modifier of muscular dystrophy

Quattrocelli, M., Spencer, M. J. & McNally, E. M., Mar 1 2017, In : Biochimica et Biophysica Acta - Molecular Cell Research. 1864, 3, p. 572-579 8 p.

Research output: Contribution to journalReview article

Muscular Dystrophies
Muscles
Regeneration
Mutation
Osteopontin
2016
13 Citations (Scopus)

Questions and Answers about Myostatin, GDF11, and the Aging Heart

McNally, E. M., Jan 8 2016, In : Circulation research. 118, 1, p. 6-8 3 p.

Research output: Contribution to journalReview article

Growth Differentiation Factors
Myostatin
Bone Morphogenetic Proteins
Cardiomegaly
2 Citations (Scopus)
Antisense Oligonucleotides
Exons
Lamin Type A
Protein Array Analysis
Inborn Genetic Diseases
2015
19 Citations (Scopus)

Membrane fusion in muscle development and repair

Demonbreun, A. R., Biersmith, B. H. & McNally, E. M., Sep 1 2015, In : Seminars in Cell and Developmental Biology. 45, p. 48-56 9 p.

Research output: Contribution to journalReview article

Membrane Fusion
Muscle Development
Myoblasts
Skeletal Muscle Fibers
Muscles
16 Citations (Scopus)

Modifier genes and their effect on Duchenne muscular dystrophy

Vo, A. H. & McNally, E. M., Oct 1 2015, In : Current Opinion in Neurology. 28, 5, p. 528-534 7 p.

Research output: Contribution to journalReview article

Modifier Genes
Duchenne Muscular Dystrophy
Muscular Dystrophies
Gene Expression Profiling
Carrier Proteins
6 Citations (Scopus)

New approaches to establish genetic causality

McNally, E. M. & George Jr, A. L., Oct 1 2015, In : Trends in Cardiovascular Medicine. 25, 7, p. 646-652 7 p.

Research output: Contribution to journalReview article

Causality
Avalanches
Genetic Testing
Genomics
Heart Diseases
46 Citations (Scopus)

The genetic landscape of cardiomyopathy and its role in heart failure

McNally, E. M., Barefield, D. Y. & Puckelwartz, M. J., Feb 3 2015, In : Cell Metabolism. 21, 2, p. 174-182 9 p.

Research output: Contribution to journalReview article

Cardiomyopathies
Heart Failure
Connectin
Mutation
Hypertrophic Cardiomyopathy
2014
4 Citations (Scopus)

Dynamin 2 the rescue for centronuclear myopathy

Demonbreun, A. R. & McNally, E. M., Mar 3 2014, In : Journal of Clinical Investigation. 124, 3, p. 976-978 3 p.

Research output: Contribution to journalReview article

Dynamin II
Congenital Structural Myopathies
Muscles
Mutation
Muscular Diseases
12 Citations (Scopus)

Genetic modifiers for neuromuscular diseases

Lamar, K. M. & McNally, E. M., Jan 1 2014, In : Journal of neuromuscular diseases. 1, 1, p. 3-13 11 p.

Research output: Contribution to journalReview article

Neuromuscular Diseases
Modifier Genes
Muscular Dystrophies
Genetic Association Studies
Animal Models
9 Citations (Scopus)

Genetic profiling for risk reduction in human cardiovascular disease

Puckelwartz, M. J. & McNally, E. M., Mar 2014, In : Genes. 5, 1, p. 214-234 21 p.

Research output: Contribution to journalReview article

Risk Reduction Behavior
Cardiomyopathies
Cardiovascular Diseases
Heart Failure
Genome
4 Citations (Scopus)

Two strikes and you're out: Gene-gene mutation interactions in HCM

Dorn, G. W. & McNally, E. M., Jul 7 2014, In : Circulation research. 115, 2, p. 208-210 3 p.

Research output: Contribution to journalReview article

Familial Hypertrophic Cardiomyopathy
Cardiac Myosins
Myosin Heavy Chains
Missense Mutation
Amino Acid Substitution
2013
226 Citations (Scopus)

Genetic mutations and mechanisms in dilated cardiomyopathy

McNally, E. M., Golbus, J. R. & Puckelwartz, M. J., Jan 2 2013, In : Journal of Clinical Investigation. 123, 1, p. 19-26 8 p.

Research output: Contribution to journalReview article

Dilated Cardiomyopathy
Mutation
Hypertrophic Cardiomyopathy
Genes
Heart Failure
23 Citations (Scopus)

Modifying muscular dystrophy through transforming growth factor-β

Ceco, E. & McNally, E. M., Sep 1 2013, In : FEBS Journal. 280, 17, p. 4198-4209 12 p.

Research output: Contribution to journalReview article

Muscular Dystrophies
Transforming Growth Factors
Muscle
Muscles
Modifier Genes
2012
42 Citations (Scopus)

Genetic Pathways of Vascular Calcification

Hofmann Bowman, M. A. & McNally, E. M., May 1 2012, In : Trends in Cardiovascular Medicine. 22, 4, p. 93-98 6 p.

Research output: Contribution to journalReview article

Vascular Calcification
Mutation
Phosphates
Inflammation
S100 Proteins
4 Citations (Scopus)
Cardiomyopathies
Muscular Dystrophies
Myocardium
Muscle Weakness
Skeletal Muscle
2011
29 Citations (Scopus)

Mechanisms and management of the heart in myotonic dystrophy

McNally, E. M. & Sparano, D., Jul 1 2011, In : Heart. 97, 13, p. 1094-1100 7 p.

Research output: Contribution to journalReview article

Cardiovascular Agents
Myotonic Dystrophy
Chromosome Aberrations
Young Adult
Heart Diseases
7 Citations (Scopus)

The emerging genetic landscape underlying cardiac conduction system function

Arnolds, D. E., Chu, A., Mcnally, E. M., Nobrega, M. A. & Moskowitz, I. P., Jun 1 2011, In : Birth Defects Research Part A - Clinical and Molecular Teratology. 91, 6, p. 578-585 8 p.

Research output: Contribution to journalReview article

Genome-Wide Association Study
Information Systems
Diptera
Heart Diseases
Electrocardiography
2010
69 Citations (Scopus)

Cardiac assessment in duchenne and becker muscular dystrophies

Romfh, A. & McNally, E. M., Dec 1 2010, In : Current Heart Failure Reports. 7, 4, p. 212-218 7 p.

Research output: Contribution to journalReview article

Duchenne Muscular Dystrophy
Dystrophin
Muscular Dystrophies
Cardiomyopathies
Guidelines
82 Citations (Scopus)

The genetics of dilated cardiomyopathy

Dellefave, L. & McNally, E. M., May 1 2010, In : Current opinion in cardiology. 25, 3, p. 198-204 7 p.

Research output: Contribution to journalReview article

Dilated Cardiomyopathy
Genetic Testing
Genes
Cardiomyopathies
Mutation
2009
179 Citations (Scopus)

Mechanisms of muscle degeneration, regeneration, and repair in the muscular dystrophies

Wallace, G. Q. & McNally, E. M., Mar 1 2009, In : Annual Review of Physiology. 71, p. 37-57 21 p.

Research output: Contribution to journalReview article

Muscular Dystrophies
Regeneration
Muscles
Gene Components
Inborn Genetic Diseases
24 Citations (Scopus)

Sarcomere Mutations in Cardiogenesis and Ventricular Noncompaction

McNally, E. & Dellefave, L., Jan 1 2009, In : Trends in Cardiovascular Medicine. 19, 1, p. 17-21 5 p.

Research output: Contribution to journalReview article

Sarcomeres
Mutation
Genes
Cardiomyopathies
Heart Failure
2007
8 Citations (Scopus)

Cardiomyopathy in neuromuscular disorders

Dellefave, L. M. & McNally, E. M., Nov 1 2007, In : Progress in Pediatric cardiology. 24, 1, p. 35-46 12 p.

Research output: Contribution to journalReview article

Cardiomyopathies
Skeletal Muscle
Sarcoglycanopathies
Myocardium
Friedreich Ataxia
59 Citations (Scopus)

Consequences of Disrupting the Dystrophin-Sarcoglycan Complex in Cardiac and Skeletal Myopathy

Heydemann, A. & McNally, E. M., Feb 1 2007, In : Trends in Cardiovascular Medicine. 17, 2, p. 55-59 5 p.

Research output: Contribution to journalReview article

Sarcoglycans
Dystrophin
Muscular Diseases
Cell Membrane
Sarcomeres
17 Citations (Scopus)

Genetic modifiers of muscular dystrophy: Implications for therapy

Heydemann, A., Doherty, K. R. & McNally, E. M., Feb 1 2007, In : Biochimica et Biophysica Acta - Molecular Basis of Disease. 1772, 2, p. 216-228 13 p.

Research output: Contribution to journalReview article

Muscular Dystrophies
Mutation
Therapeutics
Genes
Phenotype
50 Citations (Scopus)

Processing and assembly of the dystrophin glycoprotein complex

Allikian, M. J. & McNally, E. M., Mar 1 2007, In : Traffic. 8, 3, p. 177-183 7 p.

Research output: Contribution to journalReview article

Dystrophin
Muscle
Sarcolemma
Glycoproteins
Processing
2005
7 Citations (Scopus)

The interaction of coronary tone and cardiac fibrosis

Wheeler, M. T. & McNally, E. M., May 2005, In : Current atherosclerosis reports. 7, 3, p. 219-226 8 p.

Research output: Contribution to journalReview article

Blood Vessels
Fibrosis
Myofibroblasts
Fibroblasts
Myocardium
22 Citations (Scopus)

Therapy insight: Cardiovascular complications associated with muscular dystrophies

McNally, E. M. & MacLeod, H., Jun 1 2005, In : Nature Clinical Practice Cardiovascular Medicine. 2, 6, p. 301-308 8 p.

Research output: Contribution to journalReview article

Muscular Dystrophies
Skeletal Muscle
Therapeutics
Cardiomyopathies
Cardiac Myocytes
2004
46 Citations (Scopus)

Powerful genes - Myostatin regulation of human muscle mass

McNally, E. M., Jun 24 2004, In : New England Journal of Medicine. 350, 26, p. 2642-2644 3 p.

Research output: Contribution to journalReview article

Myostatin
Muscular Diseases
Transforming Growth Factor beta
Hypertrophy
Substance-Related Disorders
312 Citations (Scopus)

The Dystrophin Glycoprotein Complex: Signaling Strength and Integrity for the Sarcolemma

Lapidos, K. A., Kakkar, R. & McNally, E. M., Apr 30 2004, In : Circulation research. 94, 8, p. 1023-1031 9 p.

Research output: Contribution to journalReview article

Sarcolemma
Dystrophin
Glycoproteins
Membranes
Skeletal Muscle
2003
21 Citations (Scopus)

Cytoskeletal defects in cardiomyopathy

McNally, E., Allikian, M., Wheeler, M. T., Mislow, J. M. & Heydemann, A., Mar 1 2003, In : Journal of Molecular and Cellular Cardiology. 35, 3, p. 231-241 11 p.

Research output: Contribution to journalReview article

Cardiomyopathies
Muscle Cells
Proteins
Sarcomeres
Cytoskeletal Proteins
35 Citations (Scopus)

Sarcoglycans in vascular smooth and striated muscle

Wheeler, M. T. & McNally, E. M., Aug 2003, In : Trends in Cardiovascular Medicine. 13, 6, p. 238-243 6 p.

Research output: Contribution to journalReview article

Sarcoglycans
Striated Muscle
Vascular Smooth Muscle
Cardiomyopathies
Spasm
2001
17 Citations (Scopus)

Cardiomyopathy in animal models of muscular dystrophy

Heydemann, A., Wheeler, M. T. & McNally, E. M., Jun 11 2001, In : Current opinion in cardiology. 16, 3, p. 211-217 7 p.

Research output: Contribution to journalReview article

Animal Muscular Dystrophy
Muscular Dystrophies
Cardiomyopathies
Myocardium
Animal Models
1996
68 Citations (Scopus)

Beyond dystrophin: Current progress in the muscular dystrophies

Bönnemann, C. G., McNally, E. M. & Kunkel, L. M., Jan 1 1996, In : Current Opinion in Pediatrics. 8, 6, p. 569-582 14 p.

Research output: Contribution to journalReview article

Dystrophin
Muscular Dystrophies
Walker-Warburg Syndrome
Laminin
Sarcoglycans
1989
9 Citations (Scopus)

Bacterial expression of eukaryotic contractile proteins

Leinwand, L. A., Sohn, R., Frankel, S. A., Goodwin, E. B. & McNally, E. M., Jan 1 1989, In : Cell motility and the cytoskeleton. 14, 1, p. 3-11 9 p.

Research output: Contribution to journalReview article

Contractile Proteins
Genetic Vectors
Myosins
Recombinant Proteins
Actins