Elizabeth Thomas Bartom

  • 1158 Citations
20002020

Research output per year

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Research Output

Article

6mer seed toxicity in tumor suppressive microRNAs

Gao, Q. Q., Putzbach, W. E., Murmann, A. E., Chen, S., Sarshad, A. A., Peter, J. M., Bartom, E. T., Hafner, M. & Peter, M. E., Dec 1 2018, In : Nature communications. 9, 1, 4504.

Research output: Contribution to journalArticle

4 Scopus citations

6mer Seed Toxicity in Viral microRNAs

Murmann, A. E., Bartom, E. T., Schipma, M. J., Vilker, J., Chen, S. & Peter, M. E., Feb 21 2020, In : iScience. 23, 2, 100737.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

A Carcinogen-induced mouse model recapitulates the molecular alterations of human muscle invasive bladder cancer

Fantini, D., Glaser, A. P., Rimar, K. J., Wang, Y., Schipma, M., Varghese, N., Rademaker, A., Behdad, A., Yellapa, A., Yu, Y., Sze, C. C. L., Wang, L., Zhao, Z., Crawford, S. E., Hu, D., Licht, J. D., Collings, C. K., Bartom, E., Theodorescu, D., Shilatifard, A. & 1 others, Meeks, J. J., Apr 1 2018, In : Oncogene. 37, 14, p. 1911-1925 15 p.

Research output: Contribution to journalArticle

26 Scopus citations

A CHAF1B-Dependent Molecular Switch in Hematopoiesis and Leukemia Pathogenesis

Volk, A., Liang, K., Suraneni, P., Li, X., Zhao, J., Bulic, M., Marshall, S., Pulakanti, K., Malinge, S., Taub, J., Ge, Y., Rao, S., Bartom, E., Shilatifard, A. & Crispino, J. D., Nov 12 2018, In : Cancer Cell. 34, 5, p. 707-723.e7

Research output: Contribution to journalArticle

11 Scopus citations

Annotating large genomes with exact word matches

Healy, J., Thomas, E. E., Schwartz, J. T. & Wigler, M., Oct 1 2003, In : Genome research. 13, 10, p. 2306-2315 10 p.

Research output: Contribution to journalArticle

53 Scopus citations

Cancer-Associated IDH1 Promotes Growth and Resistance to Targeted Therapies in the Absence of Mutation

Calvert, A. E., Chalastanis, A., Wu, Y., Hurley, L. A., Kouri, F., Bi, Y., Kachman, M., May, J. L., Bartom, E. T., Hua, Y., Mishra, R. K., Schiltz, G. E., Dubrovskyi, O., Mazar, A. P., Peter, M. E., Zheng, H., James, C. D., Burant, C. F., Chandel, N., Davuluri, R. V. & 2 others, Horbinski, C. M. & Stegh, A. H., May 30 2017, In : Cell reports. 19, 9, p. 1858-1873 16 p.

Research output: Contribution to journalArticle

43 Scopus citations

CD95/fas ligand mRNA is toxic to cells

Putzbach, W., Haluck-Kangas, A., Gao, Q. Q., Sarshad, A. A., Bartom, E. T., Stults, A., Qadir, A. S., Hafner, M. & Peter, M. E., Oct 2018, In : eLife. 7, e38621.

Research output: Contribution to journalArticle

4 Scopus citations

Comparison of the genome sequences of "Candidatus portiera aleyrodidarum" primary endosymbionts of the whitefly bemisia tabaci B and Q biotypes

Jiang, Z. F., Xia, F., Johnson, K. W., Brown, C. D., Bartom, E., Tuteja, J. H., Stevens, R., Grossman, R. L., Brumin, M., White, K. P. & Ghanim, M., Mar 1 2013, In : Applied and Environmental Microbiology. 79, 5, p. 1757-1759 3 p.

Research output: Contribution to journalArticle

18 Scopus citations

Cutting edge: Lymphomyeloid-primed progenitor cell fates are controlled by the transcription factor TAL1

De Pooter, R. F., Dias, S., Chowdhury, M., Bartom, E. T., Okoreeh, M. K., Sigvardsson, M. & Kee, B. L., May 15 2019, In : Journal of Immunology. 202, 10, p. 2837-2842 6 p.

Research output: Contribution to journalArticle

CUX1 is a haploinsufficient tumor suppressor gene on chromosome 7 frequently inactivated in acute myeloid leukemia

McNerney, M. E., Brown, C. D., Wang, X., Bartom, E. T., Karmakar, S., Bandlamudi, C., Yu, S., Ko, J., Sandall, B. P., Stricker, T., Anastasi, J., Grossman, R. L., Cunningham, J. M., Le Beau, M. M. & White, K. P., Feb 7 2013, In : Blood. 121, 6, p. 975-983 9 p.

Research output: Contribution to journalArticle

85 Scopus citations

Distribution of short paired duplications in mammalian genomes

Thomas, E. E., Srebro, N., Sebat, J., Navin, N., Healy, J., Mishra, B. & Wigler, M., Jul 13 2004, In : Proceedings of the National Academy of Sciences of the United States of America. 101, 28, p. 10349-10354 6 p.

Research output: Contribution to journalArticle

22 Scopus citations

Epigenetic repression of the Igk locus by STAT5-mediated recruitment of the histone methyltransferase Ezh2

Mandal, M., Powers, S. E., Maienschein-Cline, M., Bartom, E. T., Hamel, K. M., Kee, B. L., Dinner, A. R. & Clark, M. R., Dec 1 2011, In : Nature Immunology. 12, 12, p. 1212-1220 9 p.

Research output: Contribution to journalArticle

115 Scopus citations

Exploring the characteristics of sequence elements in proximal promoters of human genes

Bina, M., Wyss, P., Ren, W., Szpankowski, W., Thomas, E., Randhawa, R., Reddy, S., John, P. M., Pares-Matos, E. I., Stein, A., Xu, H. & Lazarus, S. A., Dec 1 2004, In : Genomics. 84, 6, p. 929-940 12 p.

Research output: Contribution to journalArticle

16 Scopus citations

ExScalibur: A high-performance cloud-enabled suite for whole exome germline and somatic mutation identification

Bao, R., Hernandez, K., Huang, L., Kang, W., Bartom, E., Onel, K., Volchenboum, S. & Andrade, J., Aug 13 2015, In : PloS one. 10, 8, e0135800.

Research output: Contribution to journalArticle

6 Scopus citations

EZH2 regulates the developmental timing of effectors of the pre-Antigen receptor checkpoints

Jacobsen, J. A., Woodard, J., Mandal, M., Clark, M. R., Bartom, E. T., Sigvardsson, M. & Kee, B. L., Jun 15 2017, In : Journal of Immunology. 198, 12, p. 4682-4691 10 p.

Research output: Contribution to journalArticle

10 Scopus citations

Ezh2 represses transcription of innate lymphoid genes in B lymphocyte progenitors and maintains the B-2 cell fate

Jacobsen, J. A., Bartom, E. T., Sigvardsson, M. & Kee, B. L., Apr 1 2020, In : Journal of Immunology. 204, 7, p. 1760-1769 10 p.

Research output: Contribution to journalArticle

Genetic pathways leading to therapy-related myeloid neoplasms

Stoddart, A., McNerney, M. E., Bartom, E., Bergerson, R., Young, D. J., Qian, Z., Wang, J., Fernald, A. A., Davis, E. M., Larson, R. A., White, K. P. & Le Beau, M. M., Jan 1 2011, In : Mediterranean Journal of Hematology and Infectious Diseases. 3, 1, e2011019.

Research output: Contribution to journalArticle

11 Scopus citations

Histone H3K4 monomethylation catalyzed by Trr and mammalian COMPASS-like proteins at enhancers is dispensable for development and viability

Rickels, R., Herz, H. M., Sze, C. C., Cao, K., Morgan, M. A., Collings, C. K., Gause, M., Takahashi, Y. H., Wang, L., Rendleman, E. J., Marshall, S. A., Krueger, A., Bartom, E. T., Piunti, A., Smith, E. R., Abshiru, N. A., Kelleher, N. L., Dorsett, D. & Shilatifard, A., Nov 1 2017, In : Nature Genetics. 49, 11, p. 1647-1653 7 p.

Research output: Contribution to journalArticle

41 Scopus citations

MAGPIE/EGRET annotation of the 2.9-mb Drosophila melanogaster Adh region

Gaasterland, T., Sczyrba, A., Thomas, E., Aytekin-Kurban, G., Gordon, P. & Sensen, C. W., Apr 1 2000, In : Genome research. 10, 4, p. 502-510 9 p.

Research output: Contribution to journalArticle

19 Scopus citations

Many si/shRNAs can kill cancer cells by targeting multiple survival genes through an off-target mechanism

Putzbach, W., Gao, Q. Q., Patel, M., Van Dongen, S., Haluck-Kangas, A., Sarshad, A. A., Bartom, E. T., Kim, K. Y. A., Scholtens, D. M., Hafner, M., Zhao, J. C., Murmann, A. E. & Peter, M. E., Oct 24 2017, In : eLife. 6, e29702.

Research output: Contribution to journalArticle

17 Scopus citations

Monocyte-derived alveolar macrophages drive lung fibrosis and persist in the lung over the life span

Misharin, A. V., Morales-Nebreda, L., Reyfman, P. A., Cuda, C. M., Walter, J. M., McQuattie-Pimentel, A. C., Chen, C. I., Anekalla, K. R., Joshi, N., Williams, K. J. N., Abdala-Valencia, H., Yacoub, T. J., Chi, M., Chiu, S., Gonzalez-Gonzalez, F. J., Gates, K., Lam, A. P., Nicholson, T. T., Homan, P. J., Soberanes, S. & 23 others, Dominguez, S., Morgan, V. K., Saber, R., Shaffer, A., Hinchcliff, M., Marshall, S. A., Bharat, A., Berdnikovs, S., Bhorade, S. M., Bartom, E. T., Morimoto, R. I., Balch, W. E., Sznajder, J. I., Chandel, N. S., Mutlu, G. M., Jain, M., Gottardi, C. J., Singer, B. D., Ridge, K. M., Bagheri, N., Shilatifard, A., Budinger, G. R. S. & Perlman, H., Aug 1 2017, In : Journal of Experimental Medicine. 214, 8, p. 2387-2404 18 p.

Research output: Contribution to journalArticle

185 Scopus citations

Not All H3K4 Methylations Are Created Equal: Mll2/COMPASS Dependency in Primordial Germ Cell Specification

Hu, D., Gao, X., Cao, K., Morgan, M. A., Mas, G., Smith, E. R., Volk, A. G., Bartom, E. T., Crispino, J. D., Di Croce, L. & Shilatifard, A., Feb 2 2017, In : Molecular cell. 65, 3, p. 460-475.e6

Research output: Contribution to journalArticle

33 Scopus citations

PROBER: Oligonucleotide FISH probe design software

Navin, N., Grubor, V., Hicks, J., Leibu, E., Thomas, E., Troge, J., Riggs, M., Lundin, P., Månér, S., Sebat, J., Zetterberg, A. & Wigler, M., Oct 1 2006, In : Bioinformatics. 22, 19, p. 2437-2438 2 p.

Research output: Contribution to journalArticle

21 Scopus citations

RACK1 evolved species-specific multifunctionality in translational control through sequence plasticity within a loop domain

Rollins, M. G., Jha, S., Bartom, E. T. & Walsh, D., Jun 1 2019, In : Journal of cell science. 132, 12, jcs228908.

Research output: Contribution to journalArticle

Open Access

Regulation of MLL/COMPASS stability through its proteolytic cleavage by taspase1 as a possible approach for clinical therapy of leukemia

Zhao, Z., Wang, L., Volk, A. G., Birch, N. W., Stoltz, K. L., Bartom, E. T., Marshall, S. A., Rendleman, E. J., Nestler, C. M., Shilati, J., Schiltz, G. E., Crispino, J. D. & Shilatifard, A., Jan 1 2019, In : Genes and Development. 33, 1-2, p. 61-74 14 p.

Research output: Contribution to journalArticle

7 Scopus citations

Regulation of the imprinted Dlk1-Dio3 locus by allele-specific enhancer activity

Luo, Z., Lin, C., Woodfin, A. R., Bartom, E. T., Gao, X., Smith, E. R. & Shilatifard, A., Jan 1 2016, In : Genes and Development. 30, 1, p. 92-101 10 p.

Research output: Contribution to journalArticle

25 Scopus citations

SET1A/COMPASS and shadow enhancers in the regulation of homeotic gene expression

Cao, K., Collings, C. K., Marshall, S. A., Morgan, M. A., Rendleman, E. J., Wang, L., Sze, C. C., Sun, T., Bartom, E. T. & Shilatifard, A., Apr 15 2017, In : Genes and Development. 31, 8, p. 787-801 15 p.

Research output: Contribution to journalArticle

19 Scopus citations

Small interfering RNAs based on huntingtin trinucleotide repeats are highly toxic to cancer cells

Murmann, A. E., Gao, Q. Q., Putzbach, W. E., Patel, M., Bartom, E. T., Law, C. Y., Bridgeman, B., Chen, S., Mcmahon, K. M., Thaxton, C. S. & Peter, M. E., Mar 2018, In : EMBO Reports. 19, 3, e45336.

Research output: Contribution to journalArticle

11 Scopus citations

Tenascin-C expression contributes to pediatric brainstem glioma tumor phenotype and represents a novel biomarker of disease

Qi, J., Esfahani, D. R., Huang, T., Ozark, P., Bartom, E., Hashizume, R., Bonner, E. R., An, S., Horbinski, C. M., James, C. D. & Saratsis, A. M., May 15 2019, In : Acta Neuropathologica Communications. 7, 1, 75.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations
Open Access
10 Scopus citations

The microsatellites of Escherichia coli: Rapidly evolving repetitive DNAs in a non-pathogenic prokaryote

Metzgar, D., Thomas, E., Davis, C., Field, D. & Wills, C., Jan 30 2001, In : Molecular Microbiology. 39, 1, p. 183-190 8 p.

Research output: Contribution to journalArticle

32 Scopus citations

The Oncogenic Kaposi's Sarcoma-Associated Herpesvirus Encodes a Mimic of the Tumor-Suppressive miR-15/16 miRNA Family

Morrison, K., Manzano, M., Chung, K., Schipma, M. J., Bartom, E. T. & Gottwein, E., Dec 3 2019, In : Cell reports. 29, 10, p. 2961-2969.e6

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Therapeutic Targeting of MLL Degradation Pathways in MLL-Rearranged Leukemia

Liang, K., Volk, A. G., Haug, J. S., Marshall, S. A., Woodfin, A. R., Bartom, E. T., Gilmore, J. M., Florens, L., Washburn, M. P., Sullivan, K. D., Espinosa, J. M., Cannova, J., Zhang, J., Smith, E. R., Crispino, J. D. & Shilatifard, A., Jan 12 2017, In : Cell. 168, 1-2, p. 59-72.e13

Research output: Contribution to journalArticle

46 Scopus citations

Therapeutic targeting of polycomb and BET bromodomain proteins in diffuse intrinsic pontine gliomas

Piunti, A., Hashizume, R., Morgan, M. A., Bartom, E. T., Horbinski, C. M., Marshall, S. A., Rendleman, E. J., Ma, Q., Takahashi, Y. H., Woodfin, A. R., Misharin, A. V., Abshiru, N. A., Lulla, R. R., Saratsis, A. M., Kelleher, N. L., James, C. D. & Shilatifard, A., Apr 1 2017, In : Nature Medicine. 23, 4, p. 493-500 8 p.

Research output: Contribution to journalArticle

114 Scopus citations

Transcriptional Profiling of Synovial Macrophages Using Minimally Invasive Ultrasound-Guided Synovial Biopsies in Rheumatoid Arthritis

Mandelin, A. M., Homan, P. J., Shaffer, A. M., Cuda, C. M., Dominguez, S. T., Bacalao, E., Carns, M., Hinchcliff, M., Lee, J., Aren, K., Thakrar, A., Montgomery, A. B., Bridges, S. L., Bathon, J. M., Atkinson, J. P., Fox, D. A., Matteson, E. L., Buckley, C. D., Pitzalis, C., Parks, D. & 16 others, Hughes, L. B., Geraldino-Pardilla, L., Ike, R., Phillips, K., Wright, K., Filer, A., Kelly, S., Ruderman, E. M., Morgan, V., Abdala-Valencia, H., Misharin, A. V., Budinger, G. S., Bartom, E. T., Pope, R. M., Perlman, H. & Winter, D. R., Jun 2018, In : Arthritis and Rheumatology. 70, 6, p. 841-854 14 p.

Research output: Contribution to journalArticle

18 Scopus citations

Translatome analyses capture of opposing tissuespecific brassinosteroid signals orchestrating root meristem differentiation

Vragović, K., Selaa, A., Friedlander-Shani, L., Fridman, Y., Hacham, Y., Holland, N., Bartom, E., Mockler, T. C. & Savaldi-Goldstein, S., Jan 20 2015, In : Proceedings of the National Academy of Sciences of the United States of America. 112, 3, p. 923-928 6 p.

Research output: Contribution to journalArticle

57 Scopus citations

USP7 cooperates with NOTch1 to drive the oncogenic transcriptional program in T-cell leukemia

Jin, Q., Martinez, C. A., Arcipowski, K. M., Zhu, Y., Gutierrez-Diaz, B. T., Wang, K. K., Johnson, M. R., Volk, A. G., Wang, F., Wu, J., Grove, C., Wang, H., Sokirniy, I., Thomas, P. M., Goo, Y. A., Abshiru, N. A., Hijiya, N., Peirs, S., Vandamme, N., Berx, G. & 27 others, Goosens, S., Marshall, S. A., Rendleman, E. J., Takahashi, Y. H., Wang, L., Rawat, R., Bartom, E. T., Collings, C. K., Van Vlierberghe, P., Strikoudis, A., Kelly, S., Ueberheide, B., Mantis, C., Kandela, I., Bourquin, J. P., Bornhauser, B., Serafin, V., Bresolin, S., Paganin, M., Accordi, B., Basso, G., Kelleher, N. L., Weinstock, J., Kumar, S., Crispino, J. D., Shilatifard, A. & Ntziachristos, P., Jan 1 2019, In : Clinical Cancer Research. 25, 1, p. 222-239 18 p.

Research output: Contribution to journalArticle

Open Access
14 Scopus citations

ZNF598 Plays Distinct Roles in Interferon-Stimulated Gene Expression and Poxvirus Protein Synthesis

DiGiuseppe, S., Rollins, M. G., Bartom, E. T. & Walsh, D., May 1 2018, In : Cell reports. 23, 5, p. 1249-1258 10 p.

Research output: Contribution to journalArticle

5 Scopus citations

β-Catenin/Tcf7l2–dependent transcriptional regulation of GLUT1 gene expression by Zic family proteins in colon cancer

Zhao, Z., Wang, L., Bartom, E., Marshall, S., Rendleman, E., Ryan, C., Shilati, A., Savas, J., Chandel, N. & Shilatifard, A., Jul 31 2019, In : Science Advances. 5, 7, eaax0698.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations
Chapter

Constitutive Expression

Bartom, E., Feb 27 2013, Brenner's Encyclopedia of Genetics: Second Edition. Elsevier Inc, 1 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Multiplicity of Infection

Abedon, S. T. & Bartom, E., Feb 27 2013, Brenner's Encyclopedia of Genetics: Second Edition. Elsevier Inc, p. 509-510 2 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Plaques

Abedon, S. T. & Bartom, E., Feb 27 2013, Brenner's Encyclopedia of Genetics: Second Edition. Elsevier Inc, p. 356-357 2 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations

Quantitation of cell type-specific responses to brassinosteroid by deep sequencing of polysome-associated polyadenylated RNA

Vragović, K., Bartom, E. & Savaldi-Goldstein, S., Jan 1 2017, Methods in Molecular Biology. Humana Press Inc., p. 81-102 22 p. (Methods in Molecular Biology; vol. 1564).

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Scopus citations

Rolling Circle Replication

Bartom, E., Feb 27 2013, Brenner's Encyclopedia of Genetics: Second Edition. Elsevier Inc, 1 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Start, Stop Codons

Bartom, E., Feb 27 2013, Brenner's Encyclopedia of Genetics: Second Edition. Elsevier Inc, p. 556 1 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Temperate Phage

Bartom, E., Feb 27 2013, Brenner's Encyclopedia of Genetics: Second Edition. Elsevier Inc, p. 44 1 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Theta Replication

Bartom, E., Feb 27 2013, Brenner's Encyclopedia of Genetics: Second Edition. Elsevier Inc, p. 66 1 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Comment/debate

Genome sequences of the primary endosymbiont "Candidatus portiera aleyrodidarum" in the whitefly Bemisia tabaci B and Q biotypes

Jiang, Z. F., Xia, F., Johnson, K. W., Bartom, E., Tuteja, J. H., Stevens, R., Grossman, R. L., Brumin, M., White, K. P. & Ghanim, M., Dec 1 2012, In : Journal of bacteriology. 194, 23, p. 6678-6679 2 p.

Research output: Contribution to journalComment/debate

17 Scopus citations

Transcriptomic signatures decode Th17 cell pathogenicity

Reyfman, P. A., Bartom, E. T. & Singer, B. D., Sep 1 2016, In : Cellular and Molecular Immunology. 13, 5, p. 557-559 3 p.

Research output: Contribution to journalComment/debate

Letter

Retroviral insertional mutagenesis identifies the del(5q) genes, CXXC5, TIFAB and ETF1, as well as the wnt pathway, as potential targets in del(5q) myeloid neoplasms

Stoddart, A., Qian, Z., Fernald, A. A., Bergerson, R. J., Wang, J., Karrison, T., Anastasi, J., Bartom, E. T., Sarver, A. L., McNerney, M. E., Largaespada, D. A. & Le Beau, M. M., May 31 2016, In : Haematologica. 101, 6, p. e232-e236

Research output: Contribution to journalLetter

6 Scopus citations