Grants per year
Personal profile
Research Interests
Dr. Chadwick is Irene Heinz Given and John LaPorte Given Chair in Pediatrics, Director of the Section of Pediatric, Adolescent and Maternal HIV Infection and attending physician in Pediatric Infectious Diseases at the Ann & Robert H. Lurie Children's Hospital of Chicago. She is Professor of Pediatrics at Northwestern Feinberg School of Medicine. She joined the Northwestern faculty in 1985 after completing her pediatric residency and fellowship in Pediatric Infectious Diseases at Children's Memorial Hospital at the McGaw Medical Center of Northwestern University.
Dr. Chadwick's research career has been focused on the field of Pediatric HIV/AIDS. As a member of the NIH-funded International Maternal Pediatric Adolescent AIDS Clinical Trial (IMPAACT) network, she is chairperson of domestic and international protocols investigating the pharmacokinetics, pharmacogenomics and efficacy of new antiretroviral agents and approaches to therapy and early intensive therapy to achieve remission in HIV-infected infants, and Vice-Chair of the Cure Research Agenda Committee. She serves as Co-Principal Investigator of the NIH-funded Pediatric HIV/AIDS Cohort Study (PHACS), a prospective longitudinal cohort study investigating the long-term effects of HIV infection and antiretroviral medications in mother/infant pairs and young adults who were born with HIV or perinatally exposed to HIV. This prospective longitudinal study follows >3000 newborns, young children, adolescents, young adults. She chairs the American Academy of Pediatrics Committee on Pediatric AIDS, and is a member of the U.S. Dept of Health and Human Services Panel on Antiretroviral Therapy and Medical Management of Children Living with HIV.
I am a Pediatric Infectious Diseases Specialist who cares for infants, children and adolescents living with or exposed to HIV infection. As the primary pediatric consultant to the 24/7 Illinois Perinatal HIV Hotline, I advise obstetric and pediatric providers on the management of perinatally HIV-exposed newborns. In response to the growth of Pediatric AIDS in international settings, I have traveled to several African nations to train physicians about prevention of mother to child transmission of HIV and the management of antiretroviral therapy for children and adolescents living with HIV.
Certifications and Licenses
Pediatrics | |
Pediatric Infectious Diseases |
Training Experience
1982 | Residency, Northwestern University, McGaw Medical Center (Children’s Memorial Hospital) |
1985 | Fellowship, Northwestern University, McGaw Medical Center (Children’s Memorial Hospital) |
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
MD, University of Virginia
… → 1979
Research interests
- AIDS
- Infectious Diseases
- Medical Education
- Pediatrics
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Network
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PSTO 18: IMPAACT 2019 - Phase I/II Study of the Pharmacokinetics, Safety, and Tolerability of Abacavir/Dolutegravir/Lamivudine Dispersible and Immediate Release Tablets in HIV-1-Infected Children Less than 12 Years of Age (Per Patient Reimbursement)
Johns Hopkins University, ViiV Healthcare
10/1/19 → 6/29/24
Project: Research project
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Population Centered Health Homes (PCHH)
Chicago Department of Public Health, Health Resources and Services Administration
9/1/19 → 2/28/24
Project: Research project
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Population Centered Health Homes (PCHH)
Chicago Department of Public Health, Health Resources and Services Administration
9/1/19 → 2/28/24
Project: Research project
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PSTO 16: IMPAACT 2017 - Phase I/II Study of the Safety, Acceptability, Tolerability, and Pharmacokinetics of Oral and Long-Acting Injectable Cabotegravir and Long-Acting Injectable Rilpivirine in Virologically Suppressed HIV-Infected Children and Adolesce
Johns Hopkins University, ViiV Healthcare
1/1/19 → 12/30/22
Project: Research project
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UM1AI068632-14: IMPAACT Network LOC, Protocol Funds COVID-19 Bridge Funding
Johns Hopkins University, National Institute of Allergy and Infectious Diseases
3/16/20 → 6/16/20
Project: Research project
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Adolescents and Young Adults: The Pediatrician's Role in HIV Testing and Pre- and Postexposure HIV Prophylaxis
Committee on Pediatric Aids, Jan 1 2022, In: Pediatrics. 149, 1, e2021055207.Research output: Contribution to journal › Article › peer-review
Open Access -
Growth patterns of uninfected children born to women living with perinatally versus nonperinatally acquired HIV
the Pediatric HIV/AIDS Cohort Study (PHACS), Mar 15 2022, In: AIDS. 36, 4, p. 593-603 11 p.Research output: Contribution to journal › Article › peer-review
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Impact of CYP2B6 genotype, tuberculosis therapy, and formulation on efavirenz pharmacokinetics in infants and children under 40 months of age
Nikanjam, M., Tran, L., Chadwick, E. G., Bwakura-Dangarembizi, M., Moore, C. B., Samson, P., Spector, S. A., Chakhtoura, N., Jean-Philippe, P., Frenkel, L., Zimmer, B., Benns, A., Libous, J. & Capparelli, E. V., Mar 15 2022, In: AIDS. 36, 4, p. 525-532 8 p.Research output: Contribution to journal › Article › peer-review
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In-utero exposure to zidovudine-containing antiretroviral therapy and clonal hematopoiesis in HIV-exposed uninfected newborns
Lin, S. H., Wang, Y., Hartley, S. W., Karyadi, D. M., Lee, O. W., Zhu, B., Zhou, W., Brown, D. W., Beilstein-Wedel, E., Hazra, R., Kacanek, D., Chadwick, E. G., Marsit, C. J., Poirier, M. C., Brummel, S. S., Chanock, S. J., Engels, E. A. & MacHiela, M. J., Aug 1 2021, In: AIDS. 35, 10, p. 1525-1535 11 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Marijuana, Opioid, and Alcohol Use among Pregnant and Postpartum Individuals Living with HIV in the US
Yee, L. M., Kacanek, D., Brightwell, C., Haddad, L. B., Jao, J., Powis, K. M., Yao, T. J., Barr, E., Broadwell, C., Siminski, S., Seage, G. R. & Chadwick, E. G., Dec 2 2021, In: JAMA network open. 4, 12, e2137162.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations