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Ellen Chadwick

  • Professor, Pediatrics
  • Susan B. DePree Founders' Board Professor in Pediatric Adolescent and Maternal HIV Infection, Pediatrics
  • 3079 Citations
1983 …2020

Research output per year

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Personal profile

Research Interests

Dr. Chadwick is Irene Heinz Given and John LaPorte Given Chair in Pediatrics, Director of the Section of Pediatric, Adolescent and Maternal HIV Infection and attending physician in Pediatric Infectious Diseases at the Ann & Robert H. Lurie Children's Hospital of Chicago. She is Professor of Pediatrics at Northwestern Feinberg School of Medicine. She joined the Northwestern faculty in 1985 after completing her pediatric residency and fellowship in Pediatric Infectious Diseases at Children's Memorial Hospital at the McGaw Medical Center of Northwestern University.

Dr. Chadwick's research career has been focused on the field of Pediatric HIV/AIDS. As a member of the NIH-funded International Maternal Pediatric Adolescent AIDS Clinical Trial (IMPAACT) network, she is chairperson of domestic and international protocols investigating the pharmacokinetics, pharmacogenomics and efficacy of new antiretroviral agents and approaches to therapy and early intensive therapy to achieve remission in HIV-infected infants, and Vice-Chair of the Cure Research Agenda Committee. She serves as Co-Principal Investigator of the NIH-funded Pediatric HIV/AIDS Cohort Study (PHACS), a prospective longitudinal cohort study investigating the long-term effects of HIV infection and antiretroviral medications in mother/infant pairs and young adults who were born with HIV or perinatally exposed to HIV. This prospective longitudinal study follows >3000 newborns, young children, adolescents, young adults. She chairs the American Academy of Pediatrics Committee on Pediatric AIDS, and is a member of the U.S. Dept of Health and Human Services Panel on Antiretroviral Therapy and Medical Management of Children Living with HIV.

I am a Pediatric Infectious Diseases Specialist who cares for infants, children and adolescents living with or exposed to HIV infection. As the primary pediatric consultant to the 24/7 Illinois Perinatal HIV Hotline, I advise obstetric and pediatric providers on the management of perinatally HIV-exposed newborns. In response to the growth of Pediatric AIDS in international settings, I have traveled to several African nations to train physicians about prevention of mother to child transmission of HIV and the management of antiretroviral therapy for children and adolescents living with HIV.

Certifications and Licenses

Pediatrics
Pediatric Infectious Diseases

Training Experience

1982Residency, Northwestern University, McGaw Medical Center (Children’s Memorial Hospital)
1985Fellowship, Northwestern University, McGaw Medical Center (Children’s Memorial Hospital)

Education/Academic qualification

MD, University of Virginia

… → 1979

Research interests

  • AIDS
  • Infectious Diseases
  • Medical Education
  • Pediatrics

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Grants

Population Centered Health Homes (PCHH)

Chadwick, E. & Garofalo, R.

Chicago Department of Public Health, None

9/1/19 → 2/28/24

Project: Research project

PSTO 16: IMPAACT 2017 - Phase I/II Study of the Safety, Acceptability, Tolerability, and Pharmacokinetics of Oral and Long-Acting Injectable Cabotegravir and Long-Acting Injectable Rilpivirine in Virologically Suppressed HIV-Infected Children and Adolesce

Chadwick, E.

Johns Hopkins University

1/1/19 → 12/30/22

Project: Research project

Cardiac Toxicity in Perinatally HIV-infected Adolescents and Young Adults, a Longitudinal Study

Chadwick, E.

University of Buffalo, National Heart, Lung, and Blood Institute

11/27/18 → 5/31/21

Project: Research project

Cardiac Toxicity in Perinatally HIV-infected Adolescents and Young Adults, a Longitudinal Study

Chadwick, E.

University of Buffalo, National Heart, Lung, and Blood Institute

11/27/18 → 5/31/21

Project: Research project

Pediatric HIV/AIDS Cohort Study (PHACS) Data and Operations Center (DOC): PH200 AMP

Chadwick, E.

Harvard University, National Institute of Child Health and Human Development

9/9/15 → 7/31/20

Project: Research project

Research Output

Association of maternal antiretroviral use with microcephaly in children who are HIV-exposed but uninfected (SMARTT): a prospective cohort study

Williams, P. L., Yildirim, C., Chadwick, E. G., Van Dyke, R. B., Smith, R., Correia, K. F., DiPerna, A., Seage, G. R., Hazra, R. & Crowell, C. S., Jan 2020, In : The Lancet HIV. 7, 1, p. e49-e58

Research output: Contribution to journal › Article

    • 2 Scopus citations

    Association of Virologic Failure and Nonnucleoside Reverse Transcriptase Inhibitor Resistance Found in Antiretroviral-Naive Children Infected With Human Immunodeficiency Virus and Given Efavirenz-Based Treatment

    Higa, N., Pelz, A., Birch, D., Beck, I. A., Sils, T., Samson, P., Bwakura-Dangarembizi, M., Bolton-Moore, C., Capparelli, E., Chadwick, E. & Frenkel, L. M., Apr 30 2020, In : Journal of the Pediatric Infectious Diseases Society. 9, 2, p. 261-264 4 p.

    Research output: Contribution to journal › Article

    • Birth Prevalence of Congenital Cytomegalovirus Infection in HIV-Exposed Uninfected Children in the Era of Combination Antiretroviral Therapy

    Purswani, M. U., Russell, J. S., Dietrich, M., Malee, K., Spector, S. A., Williams, P. L., Frederick, T., Burchett, S., Redmond, S., Hoffman, H. J., Torre, P., Lee, S., Rice, M. L., Yao, T. J., Chadwick, E., Sanders, M. A., Hunter, S., Shearer, W., Paul, M., McMullen-Jackson, C. & 57 others, Eser-Jose, R., Harris, L., Baig, M. M., Villegas, A., Gaye-Robinson, L., Cooley, J. D., Blood, J., Garvie, P., Borkowsky, W., Deygoo, S., Lewis, J., Dieudonne, A., Bettica, L., Johnson, J., Surowiec, K., Knapp, K., Allison, K., Wilkins, M., Russell-Bell, J., Rosario, N., Angeli-Nieves, L., Olivera, V., Kohlhoff, S., Dennie, A., Kaye, J., Van Dyke, R., Craig, K., Sirois, P., Hutto, C., Hickman, P., Marullo, D., Figueroa, V., Loughran, M., Nichols, S., McFarland, E., Barr, E., Kwon, C., Glenny, C., Rathore, M., Stowers, K., Mahmoudi, S., Maraqa, N., Almira, R., Hayani, K., Richardson, L., Smith, R., Miller, A., Scott, G., Mogollon, M., Fernandez, G., Cuadra, A., Davtyan, M., Vinas, J., Morales-Avendano, G., Rodriguez, Z. M., Torres, L. & Scalley, N., Jan 2020, In : Journal of Pediatrics. 216, p. 82-87.e2

    Research output: Contribution to journal › Article

    • Outcomes of second-line antiretroviral therapy among children living with HIV: a global cohort analysis

    The Collaborative Initiative for Paediatric HIV Education and Research (CIPHER) Global Cohort Collaboration, Apr 1 2020, In : Journal of the International AIDS Society. 23, 4, e25477.

    Research output: Contribution to journal › Article

    Open Access

    • Antiretroviral Prescribing Practices Among Pregnant Women Living With HIV in the United States, 2008-2017

    Pediatric HIV/AIDS Cohort Study (PHACS), Dec 2 2019, In : JAMA network open. 2, 12, p. e1917669

    Research output: Contribution to journal › Article

    Open Access