Grants per year
Personal profile
Research Interests
Dr. Chadwick is Irene Heinz Given and John LaPorte Given Chair in Pediatrics, Director of the Section of Pediatric, Adolescent and Maternal HIV Infection and attending physician in Pediatric Infectious Diseases at the Ann & Robert H. Lurie Children's Hospital of Chicago. She is Professor of Pediatrics at Northwestern Feinberg School of Medicine. She joined the Northwestern faculty in 1985 after completing her pediatric residency and fellowship in Pediatric Infectious Diseases at Children's Memorial Hospital at the McGaw Medical Center of Northwestern University.
Dr. Chadwick's research career has been focused on the field of Pediatric HIV/AIDS. As a member of the NIH-funded International Maternal Pediatric Adolescent AIDS Clinical Trial (IMPAACT) network, she is chairperson of domestic and international protocols investigating the pharmacokinetics, pharmacogenomics and efficacy of new antiretroviral agents and approaches to therapy and early intensive therapy to achieve remission in HIV-infected infants, and Vice-Chair of the Cure Research Agenda Committee. She serves as Co-Principal Investigator of the NIH-funded Pediatric HIV/AIDS Cohort Study (PHACS), a prospective longitudinal cohort study investigating the long-term effects of HIV infection and antiretroviral medications in mother/infant pairs and young adults who were born with HIV or perinatally exposed to HIV. This prospective longitudinal study follows >3000 newborns, young children, adolescents, young adults. She chairs the American Academy of Pediatrics Committee on Pediatric AIDS, and is a member of the U.S. Dept of Health and Human Services Panel on Antiretroviral Therapy and Medical Management of Children Living with HIV.
I am a Pediatric Infectious Diseases Specialist who cares for infants, children and adolescents living with or exposed to HIV infection. As the primary pediatric consultant to the 24/7 Illinois Perinatal HIV Hotline, I advise obstetric and pediatric providers on the management of perinatally HIV-exposed newborns. In response to the growth of Pediatric AIDS in international settings, I have traveled to several African nations to train physicians about prevention of mother to child transmission of HIV and the management of antiretroviral therapy for children and adolescents living with HIV.
Certifications and Licenses
Pediatrics | |
Pediatric Infectious Diseases |
Training Experience
1982 | Residency, Northwestern University, McGaw Medical Center (Children’s Memorial Hospital) |
1985 | Fellowship, Northwestern University, McGaw Medical Center (Children’s Memorial Hospital) |
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
MD, Medicine, University of Virginia
… → 1979
Research interests keywords
- AIDS
- Infectious Diseases
- Medical Education
- Pediatrics
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Collaborations and top research areas from the last five years
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Clinical Trials Units for NIAID Networks, HIV Centers for Underrepresented Populations in Research (HIV CURE) CTU
Chadwick, E. (PD/PI), Muller, W. J. (PD/PI) & Simons, L. K. (PD/PI)
University of California at San Diego, National Institute of Allergy and Infectious Diseases
12/1/17 → 11/30/27
Project: Research project
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UM1AI068632-14: IMPAACT Network LOC, Protocol Funds COVID-19 Bridge Funding
Chadwick, E. (PD/PI)
Johns Hopkins University, National Institute of Allergy and Infectious Diseases
3/16/20 → 6/16/20
Project: Research project
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UM1AI068632-14: IMPAACT 2026, Pharmacokinetic Properties of Antiretroviral, Anti-Tuberculosis, and Hormonal Contraceptive Drugs during Pregnancy and Postpartum (Cost Reimburseable)
Chadwick, E. (PD/PI)
Johns Hopkins University, National Institute of Allergy and Infectious Diseases
12/1/19 → 11/30/20
Project: Research project
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PSTO 18: IMPAACT 2019 - Phase I/II Study of the Pharmacokinetics, Safety, and Tolerability of Abacavir/Dolutegravir/Lamivudine Dispersible and Immediate Release Tablets in HIV-1-Infected Children Less than 12 Years of Age (Per Patient Reimbursement)
Chadwick, E. (PD/PI)
Johns Hopkins University, ViiV Healthcare
10/1/19 → 6/29/24
Project: Research project
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Population Centered Health Homes (PCHH) - CDC STD
Chadwick, E. (PD/PI)
Chicago Department of Public Health, Centers for Disease Control
9/1/19 → 12/30/20
Project: Research project
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Association of Fatty Acid Signatures with HIV Viremia in Pregnancy
for the Pediatric HIV/AIDS Cohort Study (PHACS), Apr 1 2024, In: AIDS research and human retroviruses. 40, 4, p. 257-267 11 p.Research output: Contribution to journal › Article › peer-review
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Factors associated with internalized HIV-related stigma among biological mothers living with HIV enrolled in a US cohort study
Davtyan, M., Kacanek, D., Lee, J., Berman, C., Chadwick, E. G., Smith, R., Salomon, L. & Frederick, T., 2024, In: AIDS Care - Psychological and Socio-Medical Aspects of AIDS/HIV. 36, 2, p. 220-226 7 p.Research output: Contribution to journal › Article › peer-review
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First-trimester exposure to newer antiretroviral agents and congenital anomalies in a US cohort
Fung, K., Hernandez-Diaz, S., Zash, R., Chadwick, E. G., Van Dyke, R. B., Broadwell, C., Jao, J., Powis, K., Yee, L. M. & Williams, P. L., Sep 1 2024, In: AIDS. 38, 11, p. 1686-1695 10 p.Research output: Contribution to journal › Article › peer-review
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HIV-1 reservoir size after neonatal antiretroviral therapy and the potential to evaluate antiretroviral-therapy-free remission (IMPAACT P1115): a phase 1/2 proof-of-concept study
Persaud, D., Bryson, Y., Nelson, B. S., Tierney, C., Cotton, M. F., Coletti, A., Jao, J., Spector, S. A., Mirochnick, M., Capparelli, E. V., Costello, D., Szewczyk, J., Nicodimus, N., Stranix-Chibanda, L., Kekitiinwa, A. R., Korutaro, V., Reding, C., Carrington, M. N., Majji, S. & Yin, D. E. & 2 others, , Jan 2024, In: The Lancet HIV. 11, 1, p. e20-e30Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
Dolutegravir in Pregnancy as Compared With Current HIV Regimens in the United States
Patel, K., Huo, Y., Jao, J., Powis, K. M., Williams, P. L., Kacanek, D., Yee, L. M., Chadwick, E. G., Shiau, S., Jacobson, D. L., Brummel, S. S., Sultan-Beyer, L., Kahlert, C. R., Zash, R. & Seage, G. R., Feb 1 2023, In: Obstetrical and Gynecological Survey. 78, 2, p. 94-96 3 p.Research output: Contribution to journal › Comment/debate › peer-review