Grants per year
Personal profile
Research Interests
Dr. Beauchamp's research has focused on developing drugs for non-traditional targets through inhibiting protein-protein interactions in order to affect cellular function and target cancer cells. Current work is investigating novel interactors with mTORC components in order to developing novel therapeutic strategies that target the mTOR pathways in myeloid leukemias.
Education/Academic qualification
PhD, Georgetown University
… → 2010
Research interests
- Biochemistry: Proteins
- Blood Cancer (leukemia and lymphomas)
- Cancer Biology
- Drug Discovery
- Signal Transduction
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Network
Grants
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Targeting Novel Protein Complexes for the Treatment of Acute Myeloid Leukemia
Altman, J. K., Beauchamp, E. M., Eklund, E. A. & Platanias, L. C.
6/1/19 → 5/31/24
Project: Research project
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VA IPA for Elspeth Beauchamp
Beauchamp, E. M. & Platanias, L. C.
10/1/15 → 7/31/19
Project: Research project
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Research Output
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Discovery of novel Mnk inhibitors using mutation-based induced-fit virtual high-throughput screening
Mishra, R. K., Clutter, M. R., Blyth, G. T., Kosciuczuk, E. M., Blackburn, A. Z., Beauchamp, E. M., Schiltz, G. E. & Platanias, L. C., Oct 1 2019, In: Chemical Biology and Drug Design. 94, 4, p. 1813-1823 11 p.Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
Identification and targeting of novel CDK9 complexes in acute myeloid leukemia
Beauchamp, E. M., Abedin, S. M., Radecki, S. G., Fischietti, M., Arslan, A. DI., Blyth, G. T., Yang, A., Lantz, C., Nelson, A., Goo, Y. A., Akpan, I., Eklund, E. A., Frankfurt, O., Fish, E. N., Thomas, P. M., Altman, J. K. & Platanias, L. C., 2019, In: Blood. 133, 11, p. 1171-1185 15 p.Research output: Contribution to journal › Article › peer-review
10 Scopus citations -
Inhibitory effects of SEL201 in acute myeloid leukemia
Kosciuczuk, E. M., Kar, A. K., Blyth, G. T., Fischietti, M., Abedin, S., Mina, A. A., Siliezar, R., Rzymski, T., Brzozka, K., Eklund, E. A., Beauchamp, E. M., Eckerdt, F., Saleiro, D. & Platanias, L. C., 2019, In: Oncotarget. 10, 67, p. 7112-7121 10 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Pharmacological mTOR targeting enhances the antineoplastic effects of selective PI3Kα inhibition in medulloblastoma
Eckerdt, F., Clymer, J., Bell, J. B., Beauchamp, E. M., Blyth, G. T., Goldman, S. & Platanias, L. C., Dec 1 2019, In: Scientific reports. 9, 1, 12822.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Potent antineoplastic effects of combined PI3Kα-MNK inhibition in medulloblastoma
Eckerdt, F., Bell, J. B., Beauchamp, E. M., Clymer, J., Blyth, G. T., Kosciuczuk, E. M., Ma, Q., Chen, D. Z., Horbinski, C., Goldman, S., Munshi, H. G., Hashizume, R. & Platanias, L. C., Jun 1 2019, In: Molecular Cancer Research. 17, 6, p. 1305-1315 11 p.Research output: Contribution to journal › Article › peer-review
3 Scopus citations