Elspeth Morrison Beauchamp

Research Assistant Professor, Medicine, Hematology Oncology Division

Emaile-beauchamp@northwestern.edu

Source: Scopus

Research activity per year

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Personal profile

Research Interests

Dr. Beauchamp's research has focused on developing drugs for non-traditional targets through inhibiting protein-protein interactions in order to affect cellular function and target cancer cells. Current work is investigating novel interactors with mTORC components in order to developing novel therapeutic strategies that target the mTOR pathways in myeloid leukemias.

Education/Academic qualification

PhD, Georgetown University

… → 2010

Research interests

Biochemistry: Proteins
Blood Cancer (leukemia and lymphomas)
Cancer Biology
Drug Discovery
Signal Transduction

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1 Active
2 Finished

Targeting Novel Protein Complexes for the Treatment of Acute Myeloid Leukemia
Altman, J. K., Beauchamp, E. M., Eklund, E. A. & Platanias, L. C.
National Cancer Institute
6/1/19 → 5/31/24
Project: Research project
VA IPA for Elspeth Beauchamp
Beauchamp, E. M. & Platanias, L. C.
Jesse Brown VA Medical Center
10/1/15 → 7/31/19
Project: Research project
Elspeth Beauchamp IPA
Beauchamp, E. M. & Platanias, L. C.
Jesse Brown VA Medical Center
11/1/13 → 9/30/16
Project: Research project

1067 Citations
23 Article
2 Comment/debate
1 Chapter
1 Review article

Discovery of novel Mnk inhibitors using mutation-based induced-fit virtual high-throughput screening
Mishra, R. K., Clutter, M. R., Blyth, G. T., Kosciuczuk, E. M., Blackburn, A. Z., Beauchamp, E. M., Schiltz, G. E. & Platanias, L. C., Oct 1 2019, In: Chemical Biology and Drug Design. 94, 4, p. 1813-1823 11 p.
Research output: Contribution to journal › Article › peer-review
2 Scopus citations
Identification and targeting of novel CDK9 complexes in acute myeloid leukemia
Beauchamp, E. M., Abedin, S. M., Radecki, S. G., Fischietti, M., Arslan, A. DI., Blyth, G. T., Yang, A., Lantz, C., Nelson, A., Goo, Y. A., Akpan, I., Eklund, E. A., Frankfurt, O., Fish, E. N., Thomas, P. M., Altman, J. K. & Platanias, L. C., 2019, In: Blood. 133, 11, p. 1171-1185 15 p.
Research output: Contribution to journal › Article › peer-review
10 Scopus citations
Inhibitory effects of SEL201 in acute myeloid leukemia
Kosciuczuk, E. M., Kar, A. K., Blyth, G. T., Fischietti, M., Abedin, S., Mina, A. A., Siliezar, R., Rzymski, T., Brzozka, K., Eklund, E. A., Beauchamp, E. M., Eckerdt, F., Saleiro, D. & Platanias, L. C., 2019, In: Oncotarget. 10, 67, p. 7112-7121 10 p.
Research output: Contribution to journal › Article › peer-review

Open Access
2 Scopus citations
Pharmacological mTOR targeting enhances the antineoplastic effects of selective PI3Kα inhibition in medulloblastoma
Eckerdt, F., Clymer, J., Bell, J. B., Beauchamp, E. M., Blyth, G. T., Goldman, S. & Platanias, L. C., Dec 1 2019, In: Scientific reports. 9, 1, 12822.
Research output: Contribution to journal › Article › peer-review

Open Access
2 Scopus citations
Potent antineoplastic effects of combined PI3Kα-MNK inhibition in medulloblastoma
Eckerdt, F., Bell, J. B., Beauchamp, E. M., Clymer, J., Blyth, G. T., Kosciuczuk, E. M., Ma, Q., Chen, D. Z., Horbinski, C., Goldman, S., Munshi, H. G., Hashizume, R. & Platanias, L. C., Jun 1 2019, In: Molecular Cancer Research. 17, 6, p. 1305-1315 11 p.
Research output: Contribution to journal › Article › peer-review
3 Scopus citations