Grants per year
Personal profile
Research Interests
Dr. Beauchamp's research has focused on developing drugs for non-traditional targets through inhibiting protein-protein interactions in order to affect cellular function and target cancer cells. Current work is investigating novel interactors with mTORC components in order to developing novel therapeutic strategies that target the mTOR pathways in myeloid leukemias.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
PhD, Tumor Biology, Georgetown University
… → 2010
Research interests keywords
- Biochemistry: Proteins
- Blood Cancer (leukemia and lymphomas)
- Cancer Biology
- Drug Discovery
- Signal Transduction
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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VA IPA Elspeth Beauchamp
Platanias, L. C. (PD/PI), Platanias, L. C. (PD/PI), Beauchamp, E. M. (Other) & Beauchamp, E. M. (Other)
7/1/24 → 9/30/25
Project: Research project
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Targeting Novel Protein Complexes for the Treatment of Acute Myeloid Leukemia
Platanias, L. C. (PD/PI), Platanias, L. C. (PD/PI), Platanias, L. C. (PD/PI), Beauchamp, E. M. (Co-Investigator), Beauchamp, E. M. (Co-Investigator), Beauchamp, E. M. (Co-Investigator), Eklund, E. A. (Co-Investigator), Eklund, E. A. (Co-Investigator), Eklund, E. A. (Co-Investigator), Altman, J. K. (Other), Altman, J. K. (Other) & Altman, J. K. (Other)
6/1/19 → 5/31/25
Project: Research project
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VA IPA for Elspeth Beauchamp
Platanias, L. C. (PD/PI) & Beauchamp, E. M. (Other)
10/1/15 → 7/31/19
Project: Research project
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Elspeth Beauchamp IPA
Platanias, L. C. (PD/PI) & Beauchamp, E. M. (Other)
11/1/13 → 9/30/16
Project: Research project
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Discovery of Potent and Selective MNK Kinase Inhibitors for the Treatment of Leukemia
Vagadia, P. P., Izquierdo-Ferrer, J., Mazewski, C., Blyth, G., Beauchamp, E. M., Clutter, M. R., Stern, C. L., Mishra, R. K., Nahotko, D., Small, S., Eckerdt, F., Platanias, L. C. & Schiltz, G. E., Mar 13 2025, In: Journal of Medicinal Chemistry. 68, 5, p. 5824-5844 21 p.Research output: Contribution to journal › Article › peer-review
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Targeting CHAF1B Enhances IFN Activity against Myeloproliferative Neoplasm Cells
Saleiro, D., Kosciuczuk, E. M., Fischietti, M., Perez, R. E., Yang, G. S., Eckerdt, F., Beauchamp, E. M., Hou, Y., Wang, Q., Weinberg, R. S., Fish, E. N., Yue, F., Hoffman, R. & Platanias, L. C., May 2023, In: Cancer Research Communications. 3, 5, p. 943-951 9 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Discovery of a signaling feedback circuit that defines interferon responses in myeloproliferative neoplasms
Saleiro, D., Wen, J. Q., Kosciuczuk, E. M., Eckerdt, F., Beauchamp, E. M., Oku, C. V., Blyth, G. T., Fischietti, M., Ilut, L., Colamonici, M., Palivos, W., Atsaves, P. A., Tan, D., Kocherginsky, M., Weinberg, R. S., Fish, E. N., Crispino, J. D., Hoffman, R. & Platanias, L. C., Dec 2022, In: Nature communications. 13, 1, 1750.Research output: Contribution to journal › Article › peer-review
Open Access16 Scopus citations -
SLFN11 Negatively Regulates Noncanonical NFκB Signaling to Promote Glioblastoma Progression
Fischietti, M., Eckerdt, F., Perez, R. E., Guillen Magaña, J. N., Mazewski, C., Ho, S., Gonzalez, C., Streich, L. D., Beauchamp, E. M., Heimberger, A. B., Baran, A. H., Yue, F., James, C. D. & Platanias, L. C., 2022, In: Cancer Research Communications. 2, 9, p. 966-978 13 p.Research output: Contribution to journal › Article › peer-review
4 Scopus citations -
Inhibitory effects of Tomivosertib in acute myeloid leukemia
Suarez, M., Blyth, G. T., Mina, A. A., Kosciuczuk, E. M., Dolniak, B., Dinner, S., Altman, J. K., Eklund, E. A., Saleiro, D., Beauchamp, E. M. & Platanias, L. C., May 11 2021, In: Oncotarget. 12, 10, p. 955-966 12 p.Research output: Contribution to journal › Article › peer-review
Open Access9 Scopus citations