Grants per year
Personal profile
Research Interests
Dr. Beauchamp's research has focused on developing drugs for non-traditional targets through inhibiting protein-protein interactions in order to affect cellular function and target cancer cells. Current work is investigating novel interactors with mTORC components in order to developing novel therapeutic strategies that target the mTOR pathways in myeloid leukemias.
Education/Academic qualification
PhD, Georgetown University
… → 2010
Research interests
- Biochemistry: Proteins
- Blood Cancer (leukemia and lymphomas)
- Cancer Biology
- Drug Discovery
- Signal Transduction
Fingerprint Dive into the research topics where Elspeth Morrison Beauchamp is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
- 11 Similar Profiles
Acute Myeloid Leukemia
Medicine & Life Sciences
Medulloblastoma
Medicine & Life Sciences
Ewing's Sarcoma
Medicine & Life Sciences
Sirolimus
Medicine & Life Sciences
Phosphatidylinositol 3-Kinases
Medicine & Life Sciences
Phosphotransferases
Medicine & Life Sciences
Antineoplastic Agents
Medicine & Life Sciences
Neoplasms
Medicine & Life Sciences
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Grants 2013 2024
Targeting Novel Protein Complexes for the Treatment of Acute Myeloid Leukemia
Altman, J. K., Beauchamp, E. M., Eklund, E. A. & Platanias, L. C.
6/1/19 → 5/31/24
Project: Research project
Cyclin-Dependent Kinase 9
Protein Transport
Acute Myeloid Leukemia
Protein Biosynthesis
Heterografts
VA IPA for Elspeth Beauchamp
Beauchamp, E. M. & Platanias, L. C.
10/1/15 → 7/31/19
Project: Research project
Job Description
Immunoblotting
Transfection
Molecular Biology
Phosphotransferases
Research Output 2008 2019
1
Citation
(Scopus)
Identification and targeting of novel CDK9 complexes in acute myeloid leukemia
Beauchamp, E. M., Abedin, S. M., Radecki, S. G., Fischietti, M., Arslan, A. DI., Blyth, G. T., Yang, A., Lantz, C., Nelson, A., Goo, Y. A., Akpan, I., Eklund, E. A., Frankfurt, O., Fish, E. N., Thomas, P. M., Altman, J. K. & Platanias, L. C., Jan 1 2019, In : Blood. 133, 11, p. 1171-1185 15 p.Research output: Contribution to journal › Article
Cyclin-Dependent Kinase 9
Sirolimus
Acute Myeloid Leukemia
Cytoplasm
Chemical activation
Pharmacological mTOR targeting enhances the antineoplastic effects of selective PI3Kα inhibition in medulloblastoma
Eckerdt, F. D., Clymer, J., Bell, J. B., Beauchamp, E. M., Blyth, G. T., Goldman, S. & Platanias, L. C., Dec 1 2019, In : Scientific reports. 9, 1, 12822.Research output: Contribution to journal › Article
Open Access
Medulloblastoma
Phosphatidylinositol 3-Kinases
Antineoplastic Agents
Pharmacology
Neoplastic Stem Cells
1
Citation
(Scopus)
Potent antineoplastic effects of combined PI3Kα-MNK inhibition in medulloblastoma
Eckerdt, F. D., Bell, J. B., Beauchamp, E. M., Clymer, J., Blyth, G. T., Kosciuczuk, E. M., Ma, Q., Chen, D. Z., Horbinski, C. M., Goldman, S., Munshi, H. G., Hashizume, R. & Platanias, L. C., Jun 1 2019, In : Molecular Cancer Research. 17, 6, p. 1305-1315 11 p.Research output: Contribution to journal › Article
Medulloblastoma
Mitogen-Activated Protein Kinase Kinases
Phosphatidylinositol 3-Kinases
Antineoplastic Agents
Neoplastic Stem Cells
8
Citations
(Scopus)
Differential response of glioma stem cells to arsenic trioxide therapy is regulated by MNK1 and mRNA translation
Bell, J. B., Eckerdt, F., Dhruv, H. D., Finlay, D., Peng, S., Kim, S., Kroczynska, B., Beauchamp, E. M., Alley, K., Clymer, J., Goldman, S., Cheng, S. Y., James, C. D., Nakano, I., Horbinski, C., Mazar, A. P., Vuori, K., Kumthekar, P., Raizer, J., Berens, M. E. & 1 others, , Jan 1 2018, In : Molecular Cancer Research. 16, 1, p. 32-46 15 p.Research output: Contribution to journal › Article
MAP Kinase Kinase 1
Protein Biosynthesis
Glioma
Stem Cells
Glioblastoma
14
Citations
(Scopus)
Merestinib blocks Mnk kinase activity in acute myeloid leukemia progenitors and exhibits antileukemic effects in vitro and in vivo
Kosciuczuk, E. M., Nora Vaz Saleiro, D., Kroczynska, B., Beauchamp, E. M., Eckerdt, F. D., Blyth, G. T., Abedin, S. M., Giles, F. J., Altman, J. K. & Platanias, L. C., Jul 21 2016, In : Blood. 128, 3, p. 410-414 5 p.Research output: Contribution to journal › Article
Eukaryotic Initiation Factors
Acute Myeloid Leukemia
Phosphorylation
Phosphotransferases
Eukaryotic Initiation Factor-4E