Grants per year
Personal profile
Research Interests
My interest is in the study of the biology of the alveolar epithelium as well as the mechanisms that regulate sodium transport in alveolar epithelial cells. I am also interested in studying the mechanisms by which some respiratory diseases are accompanied of muscle dysfunction and the possible role that microRNAs play in it.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
PhD, Pharmacy, University of La Laguna
… → 1996
Research interests keywords
- Cell Biology
- Chronic Obstructive Pulmonary Disease (COPD)
- Cytoskeleton
- Gene Regulation
- Infectious Diseases: Viral
- Pharmacology
- Respiratory Diseases
- Viral Pathogenesis
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Project 1
Bharat, A. (PD/PI), Avella Patino, D. M. (Co-Investigator), Budinger, G. S. (Co-Investigator), Lecuona, E. (Co-Investigator) & Yang, W. (Other)
National Heart, Lung, and Blood Institute
9/17/24 → 7/31/29
Project: Research project
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Core C: Mouse and Technology Core
Abdala-Valencia, H. (Co-Investigator), Lecuona, E. (Co-Investigator), Wu, Q. (Co-Investigator) & Ridge, K. M. (Other)
National Heart, Lung, and Blood Institute
9/17/24 → 7/31/29
Project: Research project
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Donor nonclassical monocytes mediate primary graft dysfunction and remote organ injury following lung transplant surgery
Bharat, A. (PD/PI), Budinger, G. S. (PD/PI), Lecuona, E. (Co-Investigator), Wu, Q. (Co-Investigator) & Yan, Y. (Co-Investigator)
National Heart, Lung, and Blood Institute
1/20/24 → 12/31/28
Project: Research project
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Role of spleen educated monocytes in mediating ischemia-reperfusion injury followinglung transplant surgery
Bharat, A. (PD/PI), Budinger, G. S. (PD/PI), Lecuona, E. (Co-Investigator), Misharin, A. (Co-Investigator) & Yan, Y. (Co-Investigator)
National Heart, Lung, and Blood Institute
7/15/23 → 3/31/27
Project: Research project
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Pathogenesis of lung injury mediated by lung-restricted antibodies
Bharat, A. (PD/PI), Budinger, G. S. (PD/PI), Avella Patino, D. M. (Co-Investigator), Avella Patino, D. M. (Co-Investigator), Lecuona, E. (Co-Investigator), Misharin, A. (Co-Investigator) & Yan, Y. (Co-Investigator)
National Heart, Lung, and Blood Institute
7/15/23 → 3/31/27
Project: Research project
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Inducible CCR2+ nonclassical monocytes mediate the regression of cancer metastasis
Liu, X., Ren, Z., Tan, C., Núñez-Santana, F. L., Kelly, M. E., Yan, Y., Sun, H., Abdala-Valencia, H., Yang, W., Wu, Q., Toyoda, T., Milisav, M., Casalino-Matsuda, S. M., Lecuona, E., Cerier, E. J., Heung, L. J., Abazeed, M. E., Perlman, H., Gao, R. & Chandel, N. S. & 2 others, , Nov 15 2024, In: Journal of Clinical Investigation. 134, 22, e179527.Research output: Contribution to journal › Article › peer-review
Open Access -
The role of lung-restricted autoantibodies in the development of primary and chronic graft dysfunction
Yang, W., Lecuona, E., Wu, Q., Liu, X., Sun, H., Alam, H., Nadig, S. N. & Bharat, A., 2023, In: Frontiers in Transplantation. 2, 1237671.Research output: Contribution to journal › Review article › peer-review
Open Access -
CD11b suppresses TLR activation of nonclassical monocytes to reduce primary graft dysfunction after lung transplantation
Querrey, M., Chiu, S., Lecuona, E., Wu, Q., Sun, H., Anderson, M., Kelly, M., Ravi, S., Misharin, A. V., Kreisel, D., Bharat, A. & Budinger, G. R. S., Jul 15 2022, In: Journal of Clinical Investigation. 132, 14, e157262.Research output: Contribution to journal › Article › peer-review
Open Access17 Scopus citations -
IL-1β–dependent extravasation of preexisting lung-restricted autoantibodies during lung transplantation activates complement and mediates primary graft dysfunction
Yang, W., Cerier, E. J., Núñez-Santana, F. L., Wu, Q., Yan, Y., Kurihara, C., Liu, X., Yeldandi, A., Khurram, N., Avella-Patino, D., Sun, H., Budinger, G. R. S., Kreisel, D., Mohanakumar, T., Lecuona, E. & Bharat, A., Oct 17 2022, In: Journal of Clinical Investigation. 132, 20, e157975.Research output: Contribution to journal › Article › peer-review
Open Access8 Scopus citations -
Necroptosis triggers spatially restricted neutrophil-mediated vascular damage during lung ischemia reperfusion injury
Li, W., Terada, Y., Tyurina, Y. Y., Tyurin, V. A., Bery, A. I., Gauthier, J. M., Higashikubo, R., Tong, A. Y., Zhou, D., Nunez-Santana, F., Lecuona, E., Hassan, A., Hashimoto, K., Scozzi, D., Puri, V., Nava, R. G., Krupnick, A. S., Lavine, K. J., Gelman, A. E. & Miller, M. J. & 3 others, , Mar 8 2022, In: Proceedings of the National Academy of Sciences of the United States of America. 119, 10, e2111537119.Research output: Contribution to journal › Article › peer-review
Open Access35 Scopus citations