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Personal profile

Research Interests

I am a neuroscientist and Associate Professor of Psychiatry and Behavioral Sciences at Northwestern University’s Feinberg School of Medicine. I currently serve as Associate Director of the Mesulam Center for Cognitive Neurology and Alzheimer Disease and as Imaging Core Leader of our NIA-funded Alzheimer’s Disease Center. My research falls under the broad umbrella of aging and dementia and uses a multimodal approach to investigate two aging perspectives: primary progressive aphasia (PPA) in which neurodegenerative disease invades the language network and SuperAging in which individuals are seemingly resistant to the deleterious changes in memory associated with “normal” or more typical cognitive aging. I receive research support from the National Institutes of Health and other philanthropic sources. My investigations assist in defining the clinical and anatomical features of different dementia syndromes over the course of disease as well as identifying genetic and other risk factors. My lab uses advanced neuroimaging techniques including tau and amyloid PET as well as MRI. I also develop educational programs, support groups, and person-centered intervention programs for families and individuals living with dementia. We are currently running a clinical trial investigating the effectiveness of Communication Bridge, a telemedicine person-centered intervention to maximize quality of life for individuals with dementia.

Education/Academic qualification

PhD, Northwestern University

… → 2007

Research interests

  • Aging
  • Alzheimer's Disease
  • Dementia
  • Frontotemporal Dementia
  • Magnetic Resonance Imaging (MRI)
  • Molecular Imaging
  • Neurology
  • Neuroscience
  • Primary Progressive Aphasia
  • Quantitative MRI
  • Structural and Functional Neuroimaging

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  • Accumulation of neurofibrillary tangles and activated microglia is associated with lower neuron densities in the aphasic variant of Alzheimer’s disease

    Ohm, D. T., Fought, A. J., Martersteck, A., Coventry, C., Sridhar, J., Gefen, T. D., Weintraub, S., Bigio, E., Mesulam, M. M., Rogalski, E. & Geula, C., 2020, (Accepted/In press) In: Brain Pathology.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    1 Scopus citations
  • Age at symptom onset and death and disease duration in genetic frontotemporal dementia: an international retrospective cohort study

    Moore, K. M., Nicholas, J., Grossman, M., McMillan, C. T., Irwin, D. J., Massimo, L., Van Deerlin, V. M., Warren, J. D., Fox, N. C., Rossor, M. N., Mead, S., Bocchetta, M., Boeve, B. F., Knopman, D. S., Graff-Radford, N. R., Forsberg, L. K., Rademakers, R., Wszolek, Z. K., van Swieten, J. C., Jiskoot, L. C. & 151 others, Meeter, L. H., Dopper, E. GP., Papma, J. M., Snowden, J. S., Saxon, J., Jones, M., Pickering-Brown, S., Le Ber, I., Camuzat, A., Brice, A., Caroppo, P., Ghidoni, R., Pievani, M., Benussi, L., Binetti, G., Dickerson, B. C., Lucente, D., Krivensky, S., Graff, C., Öijerstedt, L., Fallström, M., Thonberg, H., Ghoshal, N., Morris, J. C., Borroni, B., Benussi, A., Padovani, A., Galimberti, D., Scarpini, E., Fumagalli, G. G., Mackenzie, I. R., Hsiung, G. Y. R., Sengdy, P., Boxer, A. L., Rosen, H., Taylor, J. B., Synofzik, M., Wilke, C., Sulzer, P., Hodges, J. R., Halliday, G., Kwok, J., Sanchez-Valle, R., Lladó, A., Borrego-Ecija, S., Santana, I., Almeida, M. R., Tábuas-Pereira, M., Moreno, F., Barandiaran, M., Indakoetxea, B., Levin, J., Danek, A., Rowe, J. B., Cope, T. E., Otto, M., Anderl-Straub, S., de Mendonça, A., Maruta, C., Masellis, M., Black, S. E., Couratier, P., Lautrette, G., Huey, E. D., Sorbi, S., Nacmias, B., Laforce, R., Tremblay, M. P. L., Vandenberghe, R., Damme, P. V., Rogalski, E. J., Weintraub, S., Gerhard, A., Onyike, C. U., Ducharme, S., Papageorgiou, S. G., Ng, A. S. L., Brodtmann, A., Finger, E., Guerreiro, R., Bras, J., Rohrer, J. D., Heller, C., Convery, R. S., Woollacott, I. OC., Shafei, R. M., Graff-Radford, J., Jones, D. T., Dheel, C. M., Savica, R., Lapid, M. I., Baker, M., Fields, J. A., Gavrilova, R., Domoto-Reilly, K., Poos, J. M., Van der Ende, E. L., Panman, J. L., Donker Kaat, L., Seelaar, H., Richardson, A., Frisoni, G., Mega, A., Fostinelli, S., Chiang, H. H., Alberici, A., Arighi, A., Fenoglio, C., Heuer, H., Miller, B., Karydas, A., Fong, J., João Leitão, M., Santiago, B., Duro, D., Ferreira, C., Gabilondo, A., De Arriba, M., Tainta, M., Zulaica, M., Ferreira, C., Semler, E., Ludolph, A., Landwehrmeyer, B., Volk, A. E., Miltenberger, G., Verdelho, A., Afonso, S., Tartaglia, M. C., Freedman, M., Rogaeva, E., Ferrari, C., Piaceri, I., Bessi, V., Lombardi, G., St-Onge, F., Doré, M. C., Bruffaerts, R., Vandenbulcke, M., Van den Stock, J., Mesulam, M. M., Bigio, E., Koros, C., Papatriantafyllou, J., Kroupis, C., Stefanis, L., Shoesmith, C., Robertson, E., Coppola, G., Da Silva Ramos, E. M. & Geschwind, D., Feb 2020, In: The Lancet Neurology. 19, 2, p. 145-156 12 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    20 Scopus citations
  • Anatomical evidence of an indirect pathway for word repetition

    Forkel, S. J., Rogalski, E., Drossinos Sancho, N., D'Anna, L., Luque Laguna, P., Sridhar, J., Dell'Acqua, F., Weintraub, S., Thompson, C., Mesulam, M. M. & Catani, M., Feb 11 2020, In: Neurology. 94, 6, p. e594-e606

    Research output: Contribution to journalArticlepeer-review

    Open Access
    4 Scopus citations
  • APOE is a correlate of phenotypic heterogeneity in Alzheimer disease in a national cohort

    Weintraub, S., Teylan, M., Rader, B., Chan, K. C. G., Bollenbeck, M., Kukull, W. A., Coventry, C., Rogalski, E., Bigio, E. & Mesulam, M. M., Feb 11 2020, In: Neurology. 94, 6, p. e607-e612

    Research output: Contribution to journalArticlepeer-review

    5 Scopus citations
  • Assessment of executive function declines in presymptomatic and mildly symptomatic familial frontotemporal dementia: NIH-EXAMINER as a potential clinical trial endpoint

    ARTFL/LEFFTDS consortium, Jan 1 2020, In: Alzheimer's and Dementia. 16, 1, p. 11-21 11 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    3 Scopus citations
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