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Personal profile

Research Interests

Use quantitative and molecular genetics to understand the polymorphisms that underlie multigenic traits of medical, ecological, and evolutionary importance. In addition to genetics, we use new sequencing technologies, high-throughput phenotyping assays, and other genomic tools to determine the molecular mechanisms for how genetic variation causes phenotypic differences. We have broad research interests, including responses to microbial and chemical stresses, drug sensitivities, and aging-related processes.

Education/Academic qualification

PhD, Massachusetts Institute of Technology

… → 2008

Fingerprint Dive into the research topics where Erik Christian Andersen is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 1 Similar Profiles
Caenorhabditis elegans Medicine & Life Sciences
Quantitative Trait Loci Medicine & Life Sciences
Genes Medicine & Life Sciences
Mutation Medicine & Life Sciences
Benzimidazoles Medicine & Life Sciences
Spindle Apparatus Medicine & Life Sciences
Pharmaceutical Preparations Medicine & Life Sciences
Alleles Medicine & Life Sciences

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Grants 2011 2024

Caenorhabditis
Caenorhabditis elegans
genome
Nematoda
neurophysiology
Caenorhabditis elegans
phenotypic plasticity
genes
plastics
Nematoda
natural selection
mutation
Biological Sciences
genetic variation
Caenorhabditis elegans

Research Output 2001 2019

  • 1633 Citations
  • 35 Article
  • 3 Review article

A Novel Gene Underlies Bleomycin-Response Variation in Caenorhabditis elegans

Brady, S. C., Zdraljevic, S., Bisaga, K. W., Tanny, R. E., Cook, D. E., Lee, D., Wang, Y. & Andersen, E. C., Aug 1 2019, In : Genetics. 212, 4, p. 1453-1468 16 p.

Research output: Contribution to journalArticle

Open Access
Bleomycin
Caenorhabditis elegans
Genes
Clustered Regularly Interspaced Short Palindromic Repeats
Chromosome Mapping
1 Citation (Scopus)

Natural variation in C. elegans arsenic toxicity is explained by differences in branched chain amino acid metabolism

Zdraljevic, S., Fox, B. W., Strand, C., Panda, O., Tenjo, F. J., Brady, S. C., Crombie, T. A., Doench, J. G., Schroeder, F. C. & Andersen, E. C., Apr 8 2019, In : eLife. 8

Research output: Contribution to journalArticle

Open Access
Branched Chain Amino Acids
Arsenic
Metabolism
Toxicity
3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide)
5 Citations (Scopus)

Discovery of genomic intervals that underlie nematode responses to benzimidazoles

Zamanian, M., Cook, D. E., Zdraljevic, S., Brady, S. C., Lee, D., Lee, J. & Andersen, E. C., Mar 30 2018, In : PLoS Neglected Tropical Diseases. 12, 3, e0006368.

Research output: Contribution to journalArticle

Benzimidazoles
Quantitative Trait Loci
Anthelmintics
Caenorhabditis elegans
Communicable Disease Control
2 Citations (Scopus)

Extreme allelic heterogeneity at a Caenorhabditis elegans beta-tubulin locus explains natural resistance to benzimidazoles

Hahnel, S. R., Zdraljevic, S., Rodriguez, B. C., Zhao, Y., McGrath, P. T. & Andersen, E. C., Oct 1 2018, In : PLoS pathogens. 14, 10, e1007226.

Research output: Contribution to journalArticle

Benzimidazoles
Caenorhabditis elegans
Tubulin
Innate Immunity
Albendazole
2 Citations (Scopus)

Shared genomic regions underlie natural variation in diverse toxin responses

Evans, K. S., Brady, S. C., Bloom, J. S., Tanny, R. E., Cook, D. E., Giuliani, S. E., Hippleheuser, S. W., Zamanian, M. & Andersen, E. C., Dec 1 2018, In : Genetics. 210, 4, p. 1509-1525 17 p.

Research output: Contribution to journalArticle

Quantitative Trait Loci
Genetic Loci
Chromosome Mapping
Caenorhabditis elegans
Heavy Metals